449 research outputs found

    Stability of the Scalar Potential and Symmetry Breaking in the Economical 3-3-1 Model

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    A detailed study of the criteria for stability of the scalar potential and the proper electroweak symmetry breaking pattern in the economical 3-3-1 model, is presented. For the analysis we use, and improve, a method previously developed to study the scalar potential in the two-Higgs-doublet extension of the standard model. A new theorem related to the stability of the potential is stated. As a consequence of this study, the consistency of the economical 3-3-1 model emerges.Comment: to be published in EPJ C, 13 page

    Decomposing Noise in Biochemical Signaling Systems Highlights the Role of Protein Degradation

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    AbstractStochasticity is an essential aspect of biochemical processes at the cellular level. We now know that living cells take advantage of stochasticity in some cases and counteract stochastic effects in others. Here we propose a method that allows us to calculate contributions of individual reactions to the total variability of a system’s output. We demonstrate that reactions differ significantly in their relative impact on the total noise and we illustrate the importance of protein degradation on the overall variability for a range of molecular processes and signaling systems. With our flexible and generally applicable noise decomposition method, we are able to shed new, to our knowledge, light on the sources and propagation of noise in biochemical reaction networks; in particular, we are able to show how regulated protein degradation can be employed to reduce the noise in biochemical systems

    Low-energy couplings of QCD from current correlators near the chiral limit

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    We investigate a new numerical procedure to compute fermionic correlation functions at very small quark masses. Large statistical fluctuations, due to the presence of local ``bumps'' in the wave functions associated with the low-lying eigenmodes of the Dirac operator, are reduced by an exact low-mode averaging. To demonstrate the feasibility of the technique, we compute the two-point correlator of the left-handed vector current with Neuberger fermions in the quenched approximation, for lattices with a linear extent of L~1.5 fm, a lattice spacing a~0.09 fm, and quark masses down to the epsilon-regime. By matching the results with the corresponding (quenched) chiral perturbation theory expressions, an estimate of (quenched) low-energy constants can be obtained. We find agreement between the quenched values of F extrapolated from the p-regime and extracted in the epsilon-regime.Comment: 20 pages, 5 figure

    Unconventional magnetic phase diagram of cuprate superconductor La2-xSrxCuO4 at quantum critical point x = 1/9

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    We propose a new magnetic phase diagram of La2-xSrxCuO4 around a quantum critical point x = 1/9 based on field-cooled magnetization measurements and critical fittings. A new phase boundary Tm2(H) is discovered which buries deeply below the first order vortex melting line in the vortex solid phase. The coupling between superconductivity and antiferromagnetism is found to be attractive below Tm2(H) while repulsive above. The attractive coupling between superconducting order and static antiferromagnetic order provides compelling experimental evidence that the antiferromagnetism microscopically coexists and collaborates with the high temperature superconductivity in cuprates.Comment: 17 pages, 4 figure

    The 3-3-1 model with S_4 flavor symmetry

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    We construct a 3-3-1 model based on family symmetry S_4 responsible for the neutrino and quark masses. The tribimaximal neutrino mixing and the diagonal quark mixing have been obtained. The new lepton charge \mathcal{L} related to the ordinary lepton charge L and a SU(3) charge by L=2/\sqrt{3} T_8+\mathcal{L} and the lepton parity P_l=(-)^L known as a residual symmetry of L have been introduced which provide insights in this kind of model. The expected vacuum alignments resulting in potential minimization can origin from appropriate violation terms of S_4 and \mathcal{L}. The smallness of seesaw contributions can be explained from the existence of such terms too. If P_l is not broken by the vacuum values of the scalar fields, there is no mixing between the exotic and the ordinary quarks at the tree level.Comment: 20 pages, revised versio

    Quenched divergences in the deconfined phase of SU(2) gauge theory

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    The spectrum of the overlap Dirac operator in the deconfined phase of quenched gauge theory is known to have three parts: exact zeros arising from topology, small nonzero eigenvalues that result in a non-zero chiral condensate, and the dense bulk of the spectrum, which is separated from the small eigenvalues by a gap. In this paper, we focus on the small nonzero eigenvalues in an SU(2) gauge field background at β=2.4\beta=2.4 and NT=4N_T=4. This low-lying spectrum is computed on four different spatial lattices (12312^3, 14314^3, 16316^3, and 18318^3). As the volume increases, the small eigenvalues become increasingly concentrated near zero in such a way as to strongly suggest that the infinite volume condensate diverges.Comment: 12 pages, 3 figures, version to appear in Physical Review

    In-plane and Out-of-plane Plasma Resonances in Optimally Doped La1.84Sr0.16CuO4

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    We addressed the inconsistency between the electron mass anisotropy ratios determined by the far-infrared experiments and DC conductivity measurements. By eliminating possible sources of error and increasing the sensitivity and resolution in the far-infrared reflectivity measurement on the single crystalline and on the polycrystalline La1.84Sr0.16CuO4, we have unambiguously identified that the source of the mass anisotropy problem is in the estimation of the free electron density involved in the charge transport and superconductivity. In this study we found that only 2.8 % of the total doping-induced charge density is itinerant at optimal doping. Our result not only resolves the mass anisotropy puzzle but also points to a novel electronic structure formed by the rest of the electrons that sets the stage for the high temperature superconductivity

    Quenched chiral logarithms in lattice QCD with exact chiral symmetry

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    We examine quenched chiral logarithms in lattice QCD with overlap Dirac quark. For 100 gauge configurations generated with the Wilson gauge action at β=5.8 \beta = 5.8 on the 83×24 8^3 \times 24 lattice, we compute quenched quark propagators for 12 bare quark masses. The pion decay constant is extracted from the pion propagator, and from which the lattice spacing is determined to be 0.147 fm. The presence of quenched chiral logarithm in the pion mass is confirmed, and its coefficient is determined to be δ=0.203±0.014 \delta = 0.203 \pm 0.014 , in agreement with the theoretical estimate in quenched chiral perturbation theory. Further, we obtain the topological susceptibility of these 100 gauge configurations by measuring the index of the overlap Dirac operator. Using a formula due to exact chiral symmetry, we obtain the η \eta' mass in quenched chiral perturbation theory, mη=(901±64) m_{\eta'} = (901 \pm 64) Mev, and an estimate of δ=0.197±0.027 \delta = 0.197 \pm 0.027 , which is in good agreement with that determined from the pion mass.Comment: 24 pages, 6 EPS figures; v2: some clarifications added, to appear in Physical Review

    Renormalization Group Running of Lepton Mixing Parameters in See-Saw Models with S4S_4 Flavor Symmetry

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    We study the renormalization group running of the tri-bimaximal mixing predicted by the two typical S4S_4 flavor models at leading order. Although the textures of the mass matrices are completely different, the evolution of neutrino mass and mixing parameters is found to display approximately the same pattern. For both normal hierarchy and inverted hierarchy spectrum, the quantum corrections to both atmospheric and reactor neutrino mixing angles are so small that they can be neglected. The evolution of the solar mixing angle θ12\theta_{12} depends on tanβ\tan\beta and neutrino mass spectrum, the deviation from its tri-bimaximal value could be large. Taking into account the renormalization group running effect, the neutrino spectrum is constrained by experimental data on θ12\theta_{12} in addition to the self-consistency conditions of the models, and the inverted hierarchy spectrum is disfavored for large tanβ\tan\beta. The evolution of light-neutrino masses is approximately described by a common scaling factor.Comment: 23 pages, 6figure

    Blocking Effect of an Immuno-Suppressive Agent, Cynarin, on CD28 of T-Cell Receptor

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    Purpose: Cynarin, a potential immunosuppressant that blocks the interaction between the CD28 of T-cell receptor and CD80 of antigen presenting cells, was found in Echinacea purpurea by a new pharmaceutical screening method: After Flowing Through Immobilized Receptor (AFTIR; Dong et al., J Med Chem, 49:1845-1854, 2006). This Echinacea component is the first small molecule that is able to specifically block "signal 2" of T-cell activation. Methods: In this study, we used the AFTIR method to further confirm that cynarin effectively blocked the binding between CD80 of B-cells and CD28 of T-cells, and provide details of its mechanism of action. Results: The experimental results showed that cynarin blocked about 87% of the CD28-dependent "signal 2" pathway of T-cell activation under the condition of one to one ratio of T-cell and B-cell in vitro. Theoretical structure modeling showed that cynarin binds to the "G-pocket" of CD28 (Evans et al., Nat Immunol, 6:271-279, 2005), and thus interrupts the site of interaction between CD28 and CD80. Conclusions: These results confirm both that AFTIR is a promising method for screening selective active compounds from herbal medicine and that cynarin has great potential as an immuno-suppressive agent
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