401 research outputs found

    El concepto de masa en la física clásica : aspectos históricos y didácticos

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    Different definitions of mass in classical physics are discussed in basis to their physical representation. The following questions are adressed: a) the quantitas materiae problem, b) dichotomy between inertial and gravitational masses and, c) didactic implications of the different definitíonal modalities

    El debate sobre la masa relativista : el problema definicional y otros aspectos epistemológicos

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    Some epistemological issues concerning the controversy of relativistic mass, including the translation/incommensurability problem, are presented. Properties of classical and relativistic masses and alternative ontological, functional, relational, and operational definitions are compared, including, ab initio, an operational definition of relativistic mass. It is concluded that there are a number of reasons to maintain the concept of relativistic mass in science teaching

    Role of triple fixed combination valsartan, amlodipine and hydrochlorothiazide in controlling blood pressure

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    Hypertension is one of the main risk factors for the development of cardiovascular diseases and the search for new therapeutic strategies aimed at optimizing its control remains an ongoing research and clinical challenge. In recent years, there has been a marked increase in the use of combinations of antihypertensive drugs with complementary mechanisms of action, with the aims of reducing blood pressure levels more rapidly and vigorously than strategies employing monotherapy and improving treatment compliance and adhesion. Therefore, as recommended by the 2009 reappraisal of the European Society of Hypertension/European Society of Cardiology Guidelines, the use of a triple combination that combines a calcium channel blocker, an angiotensin II receptor blocker and a thiazide diuretic seems a reasonable and efficacious combination for the management of hypertensive patients with moderate, high or very high risk. This article reviews the clinical trials carried out with the fixed combination of amlodipine/valsartan/hydrochlorothiazide at the doses recommended for each drug in monotherapy. The data show that this combination achieved greater reductions in mean sitting diastolic and systolic blood pressure than amlodipine, valsartan or hydrochlorothiazide in monotherapy, with favorable pharmacodynamic and pharmacokinetic profiles. The triple combination at high single doses should be used with caution in elderly patients and those with renal or liver failure. Although the tolerability and safety of the triple combination are good, the most-frequently reported adverse effects were peripheral edema, headache and dizziness. Analytical alterations were consistent with the already-known biochemical effects of amlodipine, valsartan or hydrochlorothiazide in monotherapy. In summary, triple-therapy with amlodipine/valsartan/hydrochlorothiazide in a single pill contributes additional advantages to fixed -combinations of two drugs, achieving a greater and more rapid reduction in blood pressure levels in a safe, well-tolerated manner

    Electrocatalysis of neurotransmitter catecholamines by 2,4,6-triphenylpyrylium ion immobilized inside zeolite Y supercages

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    2,4,6-Triphenylpyrylium ions entrapped inside the supercages of Y zeolite exert a remarkable catalytic effect toward the electrochemical oxidation of dopamine and norepinephrine (neurotrasmitter catecholamines) in neutral aqueous media.Domenech Carbo, Antonio, [email protected]

    Primera cita de cabirol, Capreolus capreolus (Linnaeus, 1758) (Artyodactila, Cervidae) per a la provincia d’Alacant

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    Se da a conocer el primer registro de recolonización del corzo, Capreolus capreolus (Linnaeus, 1758), en la provincia Alicante. La especie se ha localizado mediante fototrampeo en una de las comarcas montañosas situadas en el norte y el interior de dicho territorio. Se plantean igualmente las diferentes hipótesis de recolonización de la especie en la zona, siendo la más plausible la reintroducción natural por expansión de las poblaciones provenientes de provincias colindantes.The first record of the roe deer, Capreolus capreolus (Linnaeus, 1758), from the Alicante province is reported. This species was identified by phototrapping in one of the mountainous regions in the north of this area. The various hypotheses of recolonization of the species in the area are considered, the most plausible being natural reintroduction due to expansion of the populations from neighbouring provinces.Es dona a conèixer el primer registre de recolonització del cabirol, Capreolus capreolus (Linnaeus, 1758), a la província d’Alacant. L’espècie s’ha localitzat mitjançant parament fotogràfic en una de les comarques muntanyoses situades al nord i a l’interior del territori esmentat. Es plantegen així mateix les diferents hipòtesis de recolonització de l’espècie a la zona, la més plausible de les quals és la reintroducció natural per expansió de les poblacions provinents de les províncies limítrofes

    On-line database of voltammetric data of immobilized particles for identifying pigments and minerals in archaeometry, conservation and restoration (ELCHER database)

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    [EN] A web-based database of voltammograms is presented for characterizing artists' pigments and corrosion products of ceramic, stone and metal objects by means of the voltammetry of immobilized particles methodology. Description of the website and the database is provided. Voltammograms are, in most cases, accompanied by scanning electron microphotographs, X-ray spectra, infrared spectra acquired in attenuated total reflectance Fourier transform infrared spectroscopy mode (ATR-FTIR) and diffuse reflectance spectra in the UV-Vis-region. For illustrating the usefulness of the database two case studies involving identification of pigments and a case study describing deterioration of an archaeological metallic object are presented. (C) 2016 Elsevier B.V. All rights reserved.Research was conducted within the "Grupo de analisis cientifico de bienes culturales y patrimoniales y estudios de ciencia de la conservacion" Microcluster of the University of Valencia Excellence Campus. Financial support is gratefully acknowledged from the MINECO Projects CTQ2014-53736-C3-1-P and CTQ2014-53736-C3-2-P which are also supported with ERDF funds. The authors would like to thank to Gonzalo Girones Sarrio manager of GongDisseny Co. by the technical support for building the site structure and the structure of the database, Archbishop of Valencia, Dr. Ignacio Bosch Reig and Dr. Pilar Roig Picazo directors of the intervention project in the Basilica de la Virgen de los Desamparados de Valencia, the conservator Estrella Arcos Von Haartman (Quibla Restaura Company) and City Council Town of Malaga, the Museum of Archaeology of Xativa, its director Angel Velasco and the conservators Isabel Martinez Lazaro and Betlem Martinez for facilitating access to samples as well as Manuel Planes Insausti and Dr Jose Luis Moya Lopez technical supervisors of the Electron Microscopy Service of the Universitat Politecnica de Valencia where were carried out SEM-EDX analyses.Domenech-Carbo, A.; Domenech Carbo, MT.; Valle-Algarra, FM.; Gimeno-Adelantado, J.; Osete Cortina, L.; Bosch-Reig, F. (2016). On-line database of voltammetric data of immobilized particles for identifying pigments and minerals in archaeometry, conservation and restoration (ELCHER database). Analytica Chimica Acta. 927:1-12. https://doi.org/10.1016/j.aca.2016.04.052S11292

    Description of Solid-to-Solid Redox Processes Based on the Voltammetry of Immobilized Particles Methodology: A Logistic Approximation

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    A semiempirical model to describe the voltammetry of nontopotactic solid-to-solid redox processes occurring in the voltammetry of immobilized particles (VIMP) electrochemistry is described. It is applied to the reduction of solid metal compounds to the corresponding metal in contact with suitable electrolytes. The model is based on the assumption that the transferred charge is a logistic function of the applied potential, a situation that applies for reversible redox processes involving strongly adsorbed reactants. The model satisfactorily applies to reproduce linear potential scan curves recorded for graphite electrodes modified with different lead compounds (PbO, PbCl2·2H2O, lead-tin yellow, lead white) in contact with 0.10 M H2SO4 aqueous solution

    On the friction/tangential restitution problem: Independent friction-restitution modeling of sphere rebound with arbitrary spin

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    Most descriptions of collision events introduce coefficients of friction and tangential restitution which vary significantly with the impact angle, in contrast with the independence of the normal coefficient of restitution with this parameter. A redefinition of the coefficients of friction and tangential restitution based on the idea that friction and restitution effects can be treated as being mutually independent, provides a satisfactory description of experimental data using a ‘constant’ restitution coefficient independent on the impact angle. This independent friction-restitution modeling is developed here for the rebound of a homogeneous sphere having an arbitrary spin on a rough massive plane. The reported closure permits the interpretation of experimental data recently reported in literature
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