3,545 research outputs found
Synthetic Observations of Simulated AGN Jets: X-ray Cavities
Observations of X-ray cavities formed by powerful jets from AGN in galaxy
cluster cores are widely used to estimate the energy output of the AGN. Using
methods commonly applied to observations of clusters, we conduct synthetic
X-ray observations of 3D MHD simulated jet-ICM interactions to test the
reliability of measuring X-ray cavity power. These measurements are derived
from empirical estimates of the enthalpy content of the cavities and their
implicit ages. We explore how such physical factors as jet intermittency and
observational conditions such as orientation of the jets with respect to the
line of sight impact the reliability of observational measurements of cavity
enthalpy and age. An estimate of the errors in these quantities can be made by
directly comparing "observationally" derived values with "actual" values from
the simulations. In our tests, cavity enthalpy derived from observations was
typically within a factor of two of the simulation values. Cavity age and,
therefore, cavity power are sensitive to the accuracy of the estimated
inclination angle of the jets. Cavity age and power estimates within a factor
of two of the actual values are possible given an accurate inclination angle.Comment: 34 pages, 14 figures, accepted for publication in Ap
Three-Dimensional Simulations of Bi-Directed Magnetohydrodynamic Jets Interacting with Cluster Environments
We report on a series of three-dimensional magnetohydrodynamic simulations of
active galactic nucleus (AGN) jet propagation in realistic models of magnetized
galaxy clusters. We are primarily interested in the details of energy transfer
between jets and the intracluster medium (ICM) to help clarify what role such
flows could have in the reheating of cluster cores. Our simulated jets feature
a range of intermittency behaviors, including intermittent jets that
periodically switch on and off and one model jet that shuts down completely,
naturally creating a relic plume. The ICM into which these jets propagate
incorporates tangled magnetic field geometries and density substructure
designed to mimic some likely features of real galaxy clusters. We find that
our jets are characteristically at least 60% efficient at transferring thermal
energy to the ICM. Irreversible heat energy is not uniformly distributed,
however, instead residing preferentially in regions very near the jet/cocoon
boundaries. While intermittency affects the details of how, when, and where
this energy is deposited, all of our models generically fail to heat the
cluster cores uniformly. Both the detailed density structure and nominally weak
magnetic fields in the ICM play interesting roles in perturbing the flows,
particularly when the jets are non-steady. Still, this perturbation is never
sufficient to isotropize the jet energy deposition, suggesting that some other
ingredient is required for AGN jets to successfully reheat cluster cores.Comment: 19 pages, 18 figures, Accepted for publication in the Astrophysical
Journa
MHD Simulations of AGN Jets in a Dynamic Galaxy Cluster Medium
We present a pair of 3-d magnetohydrodynamical simulations of intermittent
jets from a central active galactic nucleus (AGN) in a galaxy cluster extracted
from a high resolution cosmological simulation. The selected cluster was chosen
as an apparently relatively relaxed system, not having undergone a major merger
in almost 7 Gyr. Despite this characterization and history, the intra-cluster
medium (ICM) contains quite active "weather". We explore the effects of this
ICM weather on the morphological evolution of the AGN jets and lobes. The
orientation of the jets is different in the two simulations so that they probe
different aspects of the ICM structure and dynamics. We find that even for this
cluster that can be characterized as relaxed by an observational standard, the
large-scale, bulk ICM motions can significantly distort the jets and lobes.
Synthetic X-ray observations of the simulations show that the jets produce
complex cavity systems, while synthetic radio observations reveal bending of
the jets and lobes similar to wide-angle tail (WAT) radio sources. The jets are
cycled on and off with a 26 Myr period using a 50% duty cycle. This leads to
morphological features similar to those in "double-double" radio galaxies.
While the jet and ICM magnetic fields are generally too weak in the simulations
to play a major role in the dynamics, Maxwell stresses can still become locally
significant.Comment: 20 pages, 14 figures, accepted for publication in the Astrophysical
Journa
Polymer depletion interaction between two parallel repulsive walls
The depletion interaction between two parallel repulsive walls confining a
dilute solution of long and flexible polymer chains is studied by
field-theoretic methods. Special attention is paid to self-avoidance between
chain monomers relevant for polymers in a good solvent. Our direct approach
avoids the mapping of the actual polymer chains on effective hard or soft
spheres. We compare our results with recent Monte Carlo simulations [A. Milchev
and K. Binder, Eur. Phys. J. B 3, 477 (1998)] and with experimental results for
the depletion interaction between a spherical colloidal particle and a planar
wall in a dilute solution of nonionic polymers [D. Rudhardt, C. Bechinger, and
P. Leiderer, Phys. Rev. Lett. 81, 1330 (1998)].Comment: 17 pages, 3 figures. Final version as publishe
A relationship between AGN jet power and radio power
Using Chandra X-ray and VLA radio data, we investigate the scaling
relationship between jet power, P_jet, and synchrotron luminosity, P_rad. We
expand the sample presented in Birzan et al. (2008) to lower radio power by
incorporating measurements for 21 gEs to determine if the Birzan et al. (2008)
P_jet-P_rad scaling relations are continuous in form and scatter from giant
elliptical galaxies (gEs) up to brightest cluster galaxies (BCGs). We find a
mean scaling relation of P_jet approximately 5.8x10^43 (P_rad/10^40)^(0.70)
erg/s which is continuous over ~6-8 decades in P_jet and P_rad with a scatter
of approximately 0.7 dex. Our mean scaling relationship is consistent with the
model presented in Willott et al. (1999) if the typical fraction of lobe energy
in non-radiating particles to that in relativistic electrons is > 100. We
identify several gEs whose radio luminosities are unusually large for their jet
powers and have radio sources which extend well beyond the densest parts of
their X-ray halos. We suggest that these radio sources are unusually luminous
because they were unable to entrain appreciable amounts of gas.Comment: Accepted for publication in the Astrophysical Journal; 8 pages, 3
color figures, 1 tabl
Influence of long-range correlated surface and near the surface disorder on the process of adsorption of long-flexible polymer chains
The influence of long-range correlated surface and decaying near surface
disorder with quenched defects is studied. We consider a correlation function
for the defects of the form , where and
being the coordinate in the direction perpendicular to the surface and
denotes the distance parallel to the surface. We investigate the process of
adsorption of long-flexible polymer chains with excluded volume interactions on
a "marginal" and attractive wall in the framework of renormalization group
field theoretical approach up to first order of perturbation theory in a double
(,)- expansion (, ) for the
semi-infinite model with the above mentioned type of
surface and near the surface disorder in the limit . In particular we
study two limiting cases. First, we investigate the scenario where the chain's
extension it much larger then . Second, we consider the case where the
chain's extension is of the order of . For both cases we obtained series
for bulk and the whole set of surface critical exponents, characterizing the
process of adsorption of long-flexible polymer chains at the surface. The
polymer linear dimensions parallel and perpendicular to the surface and the
corresponding partition functions as well as the behavior of monomer density
profiles and the fraction of adsorbed monomers at the surface and in the volume
are studied.Comment: 31 pages, 5 figures, 2 table
Measuring the non-thermal pressure in early type galaxy atmospheres: A comparison of X-ray and optical potential profiles in M87 and NGC1399
We compare the gravitational potential profiles of the elliptical galaxies
NGC 4486 (M87) and NGC 1399 (the central galaxy in the Fornax cluster) derived
from X-ray and optical data. This comparison suggests that the combined
contribution of cosmic rays, magnetic fields and micro-turbulence to the
pressure is ~10% of the gas thermal pressure in the cores of NGC 1399 and M87,
although the uncertainties in our model assumptions (e.g., spherical symmetry)
are sufficiently large that the contribution could be consistent with zero. In
the absence of any other form of non-thermal pressure support, these upper
bounds translate into upper limits on the magnetic field of ~10-20 muG at a
distance of 1'-2' from the centers of NGC1399 and M87. We show that these
results are consistent with the current paradigm of cool cluster cores, based
on the assumption that AGN activity regulates the thermal state of the gas by
injecting energy into the intra-cluster medium. The limit of ~10-20% on the
energy density in the form of relativistic protons applies not only to the
current state of the gas, but essentially to the entire history of the
intra-cluster medium, provided that cosmic ray protons evolve adiabatically and
that their spatial diffusion is suppressed.Comment: Accepted for MNRAS. 19 pages; 14 figures; expanded version in
response to comments from the refere
αEβ7 Integrin Identifies Subsets of Pro-Inflammatory Colonic CD4+ T Lymphocytes in Ulcerative Colitis.
Background and Aims
The αEβ7 integrin is crucial for retention of T lymphocytes at mucosal surfaces through its interaction with E-cadherin. Pathogenic or protective functions of these cells during human intestinal inflammation, such as ulcerative colitis [UC], have not previously been defined, with understanding largely derived from animal model data. Defining this phenotype in human samples is important for understanding UC pathogenesis and is of translational importance for therapeutic targeting of αEβ7-E-cadherin interactions.
Methods
αEβ7+ and αEβ7- colonic T cell localization, inflammatory cytokine production and expression of regulatory T cell-associated markers were evaluated in cohorts of control subjects and patients with active UC by immunohistochemistry, flow cytometry and real-time PCR of FACS-purified cell populations.
Results
CD4+αEβ7+ T lymphocytes from both healthy controls and UC patients had lower expression of regulatory T cell-associated genes, including FOXP3, IL-10, CTLA-4 and ICOS in comparison with CD4+αEβ7- T lymphocytes. In UC, CD4+αEβ7+ lymphocytes expressed higher levels of IFNγ and TNFα in comparison with CD4+αEβ7- lymphocytes. Additionally the CD4+αEβ7+ subset was enriched for Th17 cells and the recently described Th17/Th1 subset co-expressing both IL-17A and IFNγ, both of which were found at higher frequencies in UC compared to control.
Conclusion
αEβ7 integrin expression on human colonic CD4+ T cells was associated with increased production of pro-inflammatory Th1, Th17 and Th17/Th1 cytokines, with reduced expression of regulatory T cell-associated markers. These data suggest colonic CD4+αEβ7+ T cells are pro-inflammatory and may play a role in UC pathobiology
Phylogenetic classification of Cordyceps and the clavicipitaceous fungi
Cordyceps, comprising over 400 species, was historically
classified in the Clavicipitaceae, based on cylindrical asci,
thickened ascus apices and filiform ascospores, which often disarticulate into
part-spores. Cordyceps was characterized by the production of
well-developed often stipitate stromata and an ecology as a pathogen of
arthropods and Elaphomyces with infrageneric classifications
emphasizing arrangement of perithecia, ascospore morphology and host
affiliation. To refine the classification of Cordyceps and the
Clavicipitaceae, the phylogenetic relationships of 162 taxa were
estimated based on analyses consisting of five to seven loci, including the
nuclear ribosomal small and large subunits (nrSSU and
nrLSU), the elongation factor 1α (tef1), the largest
and the second largest subunits of RNA polymerase II (rpb1 and
rpb2), β-tubulin (tub), and mitochondrial ATP6
(atp6). Our results strongly support the existence of three
clavicipitaceous clades and reject the monophyly of both Cordyceps
and Clavicipitaceae. Most diagnostic characters used in current
classifications of Cordyceps (e.g., arrangement of perithecia,
ascospore fragmentation, etc.) were not supported as being phylogenetically
informative; the characters that were most consistent with the phylogeny were
texture, pigmentation and morphology of stromata. Therefore, we revise the
taxonomy of Cordyceps and the Clavicipitaceae to be
consistent with the multi-gene phylogeny. The family Cordycipitaceae
is validated based on the type of Cordyceps, C. militaris,
and includes most Cordyceps species that possess brightly coloured,
fleshy stromata. The new family Ophiocordycipitaceae is proposed
based on Ophiocordyceps Petch, which we emend. The majority of
species in this family produce darkly pigmented, tough to pliant stromata that
often possess aperithecial apices. The new genus Elaphocordyceps is
proposed for a subclade of the Ophiocordycipitaceae, which includes
all species of Cordyceps that parasitize the fungal genus
Elaphomyces and some closely related species that parasitize
arthropods. The family Clavicipitaceae s. s. is emended and
includes the core clade of grass symbionts (e.g., Balansia,
Claviceps, Epichloë, etc.), and the entomopathogenic
genus Hypocrella and relatives. In addition, the new genus
Metacordyceps is proposed for Cordyceps species that are
closely related to the grass symbionts in the Clavicipitaceae s.
s. Metacordyceps includes teleomorphs linked to
Metarhizium and other closely related anamorphs. Two new species are
described, and lists of accepted names for species in Cordyceps,
Elaphocordyceps, Metacordyceps and Ophiocordyceps
are provided
The Azimuthal Decorrelation of Jets Widely Separated in Rapidity
This study reports the first measurement of the azimuthal decorrelation
between jets with pseudorapidity separation up to five units. The data were
accumulated using the D{\O}detector during the 1992--1993 collider run of the
Fermilab Tevatron at 1.8 TeV. These results are compared to
next--to--leading order (NLO) QCD predictions and to two leading--log
approximations (LLA) where the leading--log terms are resummed to all orders in
. The final state jets as predicted by NLO QCD
show less azimuthal decorrelation than the data. The parton showering LLA Monte
Carlo {\small HERWIG} describes the data well; an analytical LLA prediction
based on BFKL resummation shows more decorrelation than the data.Comment: 6 pages with 4 figures, all uuencoded and gzippe
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