UVB radiation induced effects on cells studied by FTIR spectroscopy

We have made a preliminary analysis of the results about the eVects on tumoral cell line (lymphoid T cell line Jurkat) induced by UVB radiation (dose of 310 mJ/cm^2) with and without a vegetable mixture. In the present study, we have used two techniques: Fourier transform infrared spectroscopy (FTIR) and flow cytometry. FTIR spectroscopy has the potential to provide the identiWcation of the vibrational modes of some of the major compounds (lipid, proteins and nucleic acids) without being invasive in the biomaterials. The second technique has allowed us to perform measurements of cytotoxicity and to assess the percentage of apoptosis. We already studied the induction of apoptotic process in the same cell line by UVB radiation; in particular, we looked for correspondences and correlations between FTIR spetroscopy and flow cytometry data finding three highly probable spectroscopic markers of apoptosis (Pozzi et al. in Radiat Res 168:698-705, 2007). In the present work, the results have shown significant changes in the absorbance and spectral pattern in the wavenumber protein and nucleic acids regions after the treatments

Observation of 15 N + α resonant structures in 19 F using the thick target in inverse kinematics scattering method

The spectroscopy of 19 F is of interest for nuclear astrophysics and nuclear structure. In astrophysics, fluorine and the reactions producing and destroying it play a key role in constraining models of stars in different evolutionary stages, such as the asymptotic giant branch (AGB) stars, responsible of the production of about half of the elements heavier than Fe. In nuclear structure, 19 F has been subject to many investigations aiming at the identification of α and more exotic cluster structures. Also, its spectroscopy is very useful to constrain the nuclear properties of the 19 Ne mirror nucleus. In this work, we report on the measurement of the 15 N − α elastic scattering using the thick target inverse kinematics approach, allowing us to span a very large fluorine excitation energy range ( ∼ 6 –10 MeV). The use of 15 N − α scattering proves very useful to study α clustering in 19 F thanks to the likelihood for populating states with such a structure. Indeed, the R -matrix analysis of the measured differential cross sections shows the occurrence of many candidate α -cluster states of 19 F . It also calls for the redefinition of the spin-parity and widths of a number of 19 F states with respect to what reported in the literature

Observation of Dirac plasmons in a topological insulator

Plasmons are the quantized collective oscillations of electrons in metals and doped semiconductors. The plasmons of ordinary, massive electrons are since a long time basic ingredients of research in plasmonics and in optical metamaterials. Plasmons of massless Dirac electrons were instead recently observed in a purely two-dimensional electron system (2DEG)like graphene, and their properties are promising for new tunable plasmonic metamaterials in the terahertz and the mid-infrared frequency range. Dirac quasi-particles are known to exist also in the two-dimensional electron gas which forms at the surface of topological insulators due to a strong spin-orbit interaction. Therefore,one may look for their collective excitations by using infrared spectroscopy. Here we first report evidence of plasmonic excitations in a topological insulator (Bi2Se3), that was engineered in thin micro-ribbon arrays of different width W and period 2W to select suitable values of the plasmon wavevector k. Their lineshape was found to be extremely robust vs. temperature between 6 and 300 K, as one may expect for the excitations of topological carriers. Moreover, by changing W and measuring in the terahertz range the plasmonic frequency vP vs. k we could show, without using any fitting parameter, that the dispersion curve is in quantitative agreement with that predicted for Dirac plasmons.Comment: 11 pages, 3 figures, published in Nature Nanotechnology (2013

Exploring Holographic General Gauge Mediation

We study models of gauge mediation with strongly coupled hidden sectors, employing a hard wall background as an holographic dual description. The structure of the soft spectrum depends crucially on the boundary conditions one imposes on bulk fields at the IR wall. Generically, vector and fermion correlators have poles at zero momentum, leading to gauge mediation by massive vector messengers and/or generating Dirac gaugino masses. Instead, non-generic choices of boundary conditions let one cover all of GGM parameter space. Enriching the background with R-symmetry breaking scalars, the SSM soft term structure becomes more constrained and similar to previously studied top-down models, while retaining the more analytic control the present bottom-up approach offers.Comment: 28 pages, 4 figures; v2: typos corrected and refs adde

Coupled-Channel Effects in Collisions between Heavy Ions near the Coulomb Barrier

With the recent availability of state-of-the-art heavy-ion stable and radioactive beams, there has been a renew interest in the investigation of nuclear reactions with heavy ions. I first present the role of inelastic and transfer channel couplings in fusion reactions induced by stable heavy ions. Analysis of experimental fusion cross sections by using standard coupled-channel calculations is discussed. The role of multi-neutron transfer is investigated in the fusion process below the Coulomb barrier by analyzing $^{32}$S+$^{90,96}$Zr as benchmark reactions. The enhancement of fusion cross sections for $^{32}$S+$^{96}$Zr is well reproduced at sub-barrier energies by NTFus code calculations including the coupling of the neutron-transfer channels following the Zagrebaev semi-classical model. Similar effects for $^{40}$Ca+$^{90}$Zr and $^{40}$Ca+$^{96}$Zr fusion excitation functions are found. The breakup coupling in both the elastic scattering and in the fusion process induced by weakly bound stable projectiles is also shown to be crucial. In this lecture, full coupled-channel calculations of the fusion excitation functions are performed by using the breakup coupling for the more neutron-rich reaction and for the more weakly bound projectiles. I clearly demonstrate that Continuum-Discretized Coupled-Channel calculations are capable to reproduce the fusion enhancement from the breakup coupling in $^{6}$Li+$^{59}$Co.Comment: 14 pages. 6 figure

Clinical-pathological study on β-APP, IL-1β, GFAP, NFL, Spectrin II, 8OHdG, TUNEL, miR-21, miR-16, miR-92 expressions to verify DAI-diagnosis, grade and prognosis

Traumatic brain injury (TBI) is one of the most important death and disability cause, involving substantial costs, also in economic terms, when considering the young age of the involved subject. Aim of this paper is to report a series of patients treated at our institutions, to verify neurological results at six months or survival; in fatal cases we searched for βAPP, GFAP, IL-1β, NFL, Spectrin II, TUNEL and miR-21, miR-16, and miR-92 expressions in brain samples, to verify DAI diagnosis and grade as strong predictor of survival and inflammatory response. Concentrations of 8OHdG as measurement of oxidative stress was performed. Immunoreaction of β-APP, IL-1β, GFAP, NFL, Spectrin II and 8OHdG were significantly increased in the TBI group with respect to control group subjects. Cell apoptosis, measured by TUNEL assay, were significantly higher in the study group than control cases. Results indicated that miR-21, miR-92 and miR-16 have a high predictive power in discriminating trauma brain cases from controls and could represent promising biomarkers as strong predictor of survival, and for the diagnosis of postmortem traumatic brain injury

QCD ghost f(T)-gravity model

Within the framework of modified teleparallel gravity, we reconstruct a f(T) model corresponding to the QCD ghost dark energy scenario. For a spatially flat FRW universe containing only the pressureless matter, we obtain the time evolution of the torsion scalar T (or the Hubble parameter). Then, we calculate the effective torsion equation of state parameter of the QCD ghost f(T)-gravity model as well as the deceleration parameter of the universe. Furthermore, we fit the model parameters by using the latest observational data including SNeIa, CMB and BAO data. We also check the viability of our model using a cosmographic analysis approach. Moreover, we investigate the validity of the generalized second law (GSL) of gravitational thermodynamics for our model. Finally, we point out the growth rate of matter density perturbation. We conclude that in QCD ghost f(T)-gravity model, the universe begins a matter dominated phase and approaches a de Sitter regime at late times, as expected. Also this model is consistent with current data, passes the cosmographic test, satisfies the GSL and fits the data of the growth factor well as the LCDM model.Comment: 19 pages, 9 figures, 2 tables. arXiv admin note: substantial text overlap with arXiv:1111.726

Feasibility studies of time-like proton electromagnetic form factors at PANDA at FAIR

Simulation results for future measurements of electromagnetic proton form factors at \PANDA (FAIR) within the PandaRoot software framework are reported. The statistical precision with which the proton form factors can be determined is estimated. The signal channel $\bar p p \to e^+ e^-$ is studied on the basis of two different but consistent procedures. The suppression of the main background channel, $\textit{i.e.}$ $\bar p p \to \pi^+ \pi^-$, is studied. Furthermore, the background versus signal efficiency, statistical and systematical uncertainties on the extracted proton form factors are evaluated using two different procedures. The results are consistent with those of a previous simulation study using an older, simplified framework. However, a slightly better precision is achieved in the PandaRoot study in a large range of momentum transfer, assuming the nominal beam conditions and detector performance

Feasibility studies of the time-like proton electromagnetic form factor measurements with PANDA at FAIR

The possibility of measuring the proton electromagnetic form factors in the time-like region at FAIR with the \PANDA detector is discussed. Detailed simulations on signal efficiency for the annihilation of $\bar p +p$ into a lepton pair as well as for the most important background channels have been performed. It is shown that precision measurements of the differential cross section of the reaction $\bar p +p \to e^++ e^-$ can be obtained in a wide angular and kinematical range. The individual determination of the moduli of the electric and magnetic proton form factors will be possible up to a value of momentum transfer squared of $q^2\simeq 14$ (GeV/c)$^2$. The total $\bar p +p\to e^++e^-$ cross section will be measured up to $q^2\simeq 28$ (GeV/c)$^2$. The results obtained from simulated events are compared to the existing data. Sensitivity to the two photons exchange mechanism is also investigated.Comment: 12 pages, 4 tables, 8 figures Revised, added details on simulations, 4 tables, 9 figure