188 research outputs found
EveTAR: Building a Large-Scale Multi-Task Test Collection over Arabic Tweets
- Author
- Publication venue
- Publication date
- 21/08/2017
- Field of study
This article introduces a new language-independent approach for creating a
large-scale high-quality test collection of tweets that supports multiple
information retrieval (IR) tasks without running a shared-task campaign. The
adopted approach (demonstrated over Arabic tweets) designs the collection
around significant (i.e., popular) events, which enables the development of
topics that represent frequent information needs of Twitter users for which
rich content exists. That inherently facilitates the support of multiple tasks
that generally revolve around events, namely event detection, ad-hoc search,
timeline generation, and real-time summarization. The key highlights of the
approach include diversifying the judgment pool via interactive search and
multiple manually-crafted queries per topic, collecting high-quality
annotations via crowd-workers for relevancy and in-house annotators for
novelty, filtering out low-agreement topics and inaccessible tweets, and
providing multiple subsets of the collection for better availability. Applying
our methodology on Arabic tweets resulted in EveTAR , the first
freely-available tweet test collection for multiple IR tasks. EveTAR includes a
crawl of 355M Arabic tweets and covers 50 significant events for which about
62K tweets were judged with substantial average inter-annotator agreement
(Kappa value of 0.71). We demonstrate the usability of EveTAR by evaluating
existing algorithms in the respective tasks. Results indicate that the new
collection can support reliable ranking of IR systems that is comparable to
similar TREC collections, while providing strong baseline results for future
studies over Arabic tweets
Molecular analysis of the vaginal response to estrogens in the ovariectomized rat and postmenopausal woman
- Author
- A Grey
- A Subramanian
- A Suzuki
- AG Geiser
- AJ Dunbar
- Andrew J Dorner
- Bryan J Peano
- BS Komm
- CM Klinge
- DC Deecher
- DL Wheeler
- ER Levin
- Eugene L Brown
- Ewa Wilson
- H Darwish
- Heather A Harris
- HZ Ke
- J Frasor
- JD Woodruff
- JM Borthwick
- JM Daly
- JS Crabtree
- Judy S Crabtree
- Kathryn Saraf
- KB Adelson
- L Tian
- LA Sorbera
- LA Willhite
- M Cotreau
- Monette M Cotreau
- MR Rubin
- R O'Lone
- Richard C Winneker
- RR Beerli
- S Bauersachs
- SA McCarroll
- Scott A Jelinsky
- Sung E Choe
- T Barrett
- T Wada
- Xiaochun Zhang
- XX Wu
- Publication venue
- BioMed Central
- Publication date
- 01/06/2008
- Field of study
<p>Abstract</p> <p>Background</p> <p>Vaginal atrophy (VA) is the thinning of the vaginal epithelial lining, typically the result of lowered estrogen levels during menopause. Some of the consequences of VA include increased susceptibility to bacterial infection, pain during sexual intercourse, and vaginal burning or itching. Although estrogen treatment is highly effective, alternative therapies are also desired for women who are not candidates for post-menopausal hormone therapy (HT). The ovariectomized (OVX) rat is widely accepted as an appropriate animal model for many estrogen-dependent responses in humans; however, since reproductive biology can vary significantly between mammalian systems, this study examined how well the OVX rat recapitulates human biology.</p> <p>Methods</p> <p>We analyzed 19 vaginal biopsies from human subjects pre and post 3-month 17ÎČ-estradiol treated by expression profiling. Data were compared to transcriptional profiling generated from vaginal samples obtained from ovariectomized rats treated with 17ÎČ-estradiol for 6 hrs, 3 days or 5 days. The level of differential expression between pre- vs. post- estrogen treatment was calculated for each of the human and OVX rat datasets. Probe sets corresponding to orthologous rat and human genes were mapped to each other using NCBI Homologene.</p> <p>Results</p> <p>A positive correlation was observed between the rat and human responses to estrogen. Genes belonging to several biological pathways and GO categories were similarly differentially expressed in rat and human. A large number of the coordinately regulated biological processes are already known to be involved in human VA, such as inflammation, epithelial development, and EGF pathway activation.</p> <p>Conclusion</p> <p>At the transcriptional level, there is evidence of significant overlap of the effects of estrogen treatment between the OVX rat and human VA samples.</p
Understanding liver regeneration to bring new insights to the mechanisms driving cholangiocarcinoma
- Author
- A Claperon
- A Claperon
- A Gentilini
- A Techasen
- A Techasen
- A Villanueva
- AE Sirica
- AEA Bergquist
- AFV Holczbauer
- AG Cox
- B Glimelius
- B Goeppert
- B Sripa
- BMY Fan
- BS Ding
- C Chuaysri
- C Raggi
- C Subimerb
- CD Fingas
- CK Ong
- CM Weisend
- D Hanahan
- D Malka
- D Yamada
- D Zhou
- DJ Murphy
- E Stocker
- EG Fritcher
- EG Huntzicker
- GA Michelotti
- GK Bonney
- GK Michalopoulos
- H Clevers
- H Hasita
- H Okabe
- H Okabe
- J Milano
- J Valle
- JB Andersen
- JC Mertens
- JM Banales
- K Kajiyama
- K Overturf
- K Yanger
- KP Lee
- L Boulter
- L Planas-Paz
- M Cadamuro
- M Ducreux
- M El Khatib
- M El Khatib
- M Fausther
- M Huch
- M Komuta
- M Lardelli
- M Swiderska-Syn
- MSB Komuta
- N Tokumoto
- P Beatus
- P Marti
- P Wang
- Q Gao
- R Carpentier
- R Espanol-Suner
- RV Guest
- RV Guest
- S Attia
- S Darwish Murad
- S Ohira
- S Rao
- S Sekiya
- S Sekiya
- S Zender
- SJ Bray
- SJ Lubner
- SL Zhou
- T Ikenoue
- T Oda
- T Okusaka
- T Zhan
- TG Bird
- TY Choi
- V Gebbia
- W Loilome
- WR Gordon
- WY Lu
- Y Kim
- YPA Zong
- ZD Burke
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 22/05/2017
- Field of study
Mapping inequalities in exclusive breastfeeding in low- and middle-income countries, 2000â2018
- Author
- Abady GG
- Abd-Allah F
- Abdelalim A
- Abebo ZH
- Abejie AN
- Abosetugn AE
- Abreu LG
- Abrigo MRM
- Abu-Gharbieh E
- Abushouk AI
- Adamu AL
- Adedeji IA
- Adegbosin AE
- Adekanmbi V
- Adetokunboh OO
- Agudelo-Botero M
- Aji B
- Akinyemi OO
- Alamneh AA
- Alanezi FM
- Alanzi TM
- Albright J
- Alcalde-Rabanal JE
- Alemu BW
- Alhassan RK
- Ali BA
- Ali S
- Alinia C
- Alipour V
- Amit AML
- Amugsi DA
- Anbesu EW
- Ancuceanu R
- Anjomshoa M
- Ansari F
- Antonio CAT
- Anvari D
- Arabloo J
- Arora A
- Artanti KD
- Asemahagn MA
- Asmare WN
- Atout MMW
- Ausloos M
- Awoke N
- Ayanore MA
- Aynalem YA
- Ayza MA
- Azene ZN
- Badiye AD
- Baig AA
- Bakkannavar SM
- Banach M
- Banik PC
- Basaleem H
- Bayati M
- Baye BA
- Bedi N
- Belay SA
- Bhagavathula AS
- Bhandari D
- Bhardwaj N
- Bhardwaj P
- Bhattacharjee NV
- Bhutta ZA
- Bijani A
- Birhan TA
- Birihane BM
- Bitew ZW
- Bohlouli S
- Bohluli M
- Bojia HA
- Boloor A
- Brady OJ
- Bragazzi NL
- Brunoni AR
- Budhathoki SS
- Butt ZA
- BĂ€rnighausen TW
- Castaldelli-Maia JM
- Castro F
- Cernigliaro A
- Charan J
- Chatterjee P
- Chatterjee S
- Chattu VK
- Chaturvedi S
- Chowdhury MAK
- Chu D-T
- Collison ML
- Cook AJ
- Cork MA
- Couto RAS
- CĂĄrdenas R
- Dagnew B
- Dai H
- Dandona L
- Dandona R
- Daneshpajouhnejad P
- Darshan BB
- Darwesh AM
- Darwish AH
- Daryani A
- Das JK
- Davis AC
- de Hidru, HD
- Denova-Gutiérrez E
- Deribe K
- Desalew A
- Deshpande A
- Dessie A
- Deuba K
- Dharmaratne SD
- Dhimal M
- Dhungana GP
- Diaz D
- Didarloo A
- Dipeolu IO
- Doan LP
- Donkers KM
- Duko B
- Duraes AR
- Dwyer-Lindgren L
- DĂĄvila-Cervantes CA
- Earl L
- El-Jaafary SI
- Elema TB
- Elhabashy HR
- Faris PS
- Faro A
- Farzadfar F
- Feigin VL
- Feleke BE
- Ferede TY
- Fischer F
- Foigt NA
- Folayan MO
- Franklin RC
- Gad MM
- Gaidhane S
- Gardner WM
- Geberemariyam BS
- Gebregiorgis BG
- Gebremedhin KB
- Gebremichael B
- Ghaffarpasand F
- Gilani SA
- Ginindza TG
- Glagn M
- Golechha M
- Gonfa KB
- Goulart BNG
- Gudi N
- Guido D
- Guled RA
- Guo Y
- Gupta RD
- Hamidi S
- Handiso DW
- Hasaballah AI
- Hassan A
- Hay SI
- Hay SI
- Hayat K
- Hegazy MI
- Heidari B
- Henry NJ
- Herteliu C
- Ho HC
- Hoang CL
- Holla R
- Hon J
- Hosseini M
- Hosseinzadeh M
- Househ M
- Hsairi M
- Hu G
- Huda TM
- Hwang B-F
- Ibitoye SE
- Ilesanmi OS
- Ilic IM
- Ilic MD
- Inbaraj LR
- Iqbal U
- Irvani SSN
- Islam MM
- Iwu CCD
- Iwu CJ
- Jain A
- Janodia MD
- Javaheri T
- John-Akinola YO
- Johnson KB
- Joukar F
- Jozwiak JJ
- Jr
- Kabir A
- Kalankesh LR
- Kalhor R
- Kamath A
- Kamyari N
- Kanchan OT
- Kapoor N
- Karimi SE
- Karyani AK
- Kasaye HK
- Kassahun G
- Kassebaum NJ
- Kayode GA
- Keiyoro PN
- Kelkay B
- Khalid N
- Khan MN
- Khaneghah AM
- Khatab K
- Khater AM
- Khater MM
- Khatib MN
- Kim YJ
- Kimokoti RW
- Kinyoki DK
- Kisa A
- Kisa S
- Kosen S
- Krishan K
- Kulkarni V
- Kumar GA
- Kumar M
- Kumar N
- Kumar P
- Kurmi OP
- Kusuma D
- Lad SD
- Lami FH
- Landires I
- Lansingh VC
- Lasrado S
- Lazzar-Atwood A
- Lee PH
- LeGrand KE
- Letourneau ID
- Lewycka S
- Li B
- Li M-C
- Li S
- Liu X
- Local Burden of Disease Exclusive Breastfeeding Collaborators
- Lodha R
- Lopez JCF
- Louie C
- Lu D
- Machado DB
- Mahesh PA
- Maled V
- Maleki S
- Malta DC
- Mamun AA
- Manafi N
- Mansournia MA
- Mapoma CC
- Marczak LB
- Martins-Melo FR
- Matin BK
- Mehndiratta MM
- Mejia-Rodriguez F
- Mekonnen TC
- Mendoza W
- Menezes RG
- Mengesha EW
- Mersha AM
- Miller TR
- Mini GK
- Mirrakhimov EM
- Misra S
- Moghadaszadeh M
- Mohammad DK
- Mohammadian-Hafshejani A
- Mohammed JA
- Mohammed S
- Mokdad AH
- Montero-Zamora PA
- Moradi M
- Moradzadeh R
- Moraga P
- Mosser JF
- Mousavi SM
- Munro SB
- Muriithi MK
- Mustafa G
- Muthupandian S
- Nagaraja SB
- Nagarajan AJ
- Naik G
- Naimzada MD
- Nangia V
- Nascimento BR
- Nayak VC
- Ndejjo R
- Ndwandwe DE
- Negoi I
- Nguefack-Tsague G
- Ngunjiri JW
- Nguyen CT
- Nguyen DN
- Nguyen HLT
- Nigussie SN
- Nigussie TTN
- Nikbakhsh R
- Nnaji CA
- Nunez-Samudio V
- Oancea B
- Oghenetega OB
- Olagunju AT
- Olusanya BO
- Olusanya JO
- Omer MO
- Onwujekwe OE
- Ortega-Altamirano DV
- Osgood-Zimmerman AE
- Otstavnov N
- Otstavnov SS
- Owolabi MO
- Padubidri JR
- Pana A
- Pandey A
- Pandi-Perumal SR
- Pangaribuan HU
- Parsekar SS
- Pasupula DK
- Patel UK
- Pathak A
- Pathak M
- Pattanshetty SM
- Patton GC
- Paulos K
- Pepito VCF
- Pickering BV
- Pinheiro M
- Piwoz EG
- Pokhrel KN
- Pourjafar H
- Prada SI
- Pribadi DRA
- Quintanilla BPA
- Rabiee M
- Rabiee N
- Rahim F
- Rahimzadeh S
- Rahman A
- Rahman MHU
- Rahmani AM
- Rai RK
- Ranabhat CL
- Rao SJ
- Rastogi P
- Rathi P
- Rawaf DL
- Rawaf S
- Rawassizadeh R
- Rawat R
- Rawat R
- Regassa LD
- Rego MAS
- Reiner RC
- Reshmi B
- Rezapour A
- Ribeiro AI
- Rickard J
- Roever L
- Rumisha SF
- Rwegerera GM
- Sagar R
- Sajadi SM
- Salem MR
- Samy AM
- Santric-Milicevic MM
- Saraswathy SYI
- Sarker AR
- Sartorius B
- Sathian B
- Saxena D
- Sbarra AN
- Schaeffer LE
- Schipp MF
- Sengupta D
- Senthilkumaran S
- Sha F
- Shafaat O
- Shaheen AA
- Shaikh MA
- Shalash AS
- Shannawaz M
- Sheikh A
- Shetty BSK
- Shetty RS
- Shibuya K
- Shiferaw WS
- Shin JI
- Silva DAS
- Singh NP
- Singh P
- Singh S
- Sintayehu Y
- Skryabin VY
- Skryabina AA
- Soheili A
- Soltani S
- Sorrie MB
- Spurlock EE
- Steuben KM
- Sudaryanto A
- Sufiyan MB
- Swartz SJ
- Syed ZQ
- Tadesse EG
- Tamiru AT
- Tantawi ME
- Tapak L
- Tareque MI
- Tarigan IU
- Tesema GA
- Tesfay FH
- Teshome A
- Tessema ZT
- Thankappan KR
- Thapar R
- Thomas N
- Topor-Madry R
- Tovani-Palone MR
- Traini E
- Tran BX
- Truong PN
- Tsegaye BTBT
- Ullah I
- Umeokonkwo CD
- Unnikrishnan B
- Upadhyay E
- Uzochukwu BSC
- VanderHeide JD
- Vecchia CL
- Violante FS
- Vo B
- Wado YD
- Waheed Y
- Wamai RG
- Wang F
- Wang Y
- Wang Y-P
- Weaver ND
- Wickramasinghe ND
- Wiens KE
- Wiysonge CS
- Woyczynski L
- Wu A-M
- Wu C
- Yamada T
- Yaya S
- Yeshaneh A
- Yeshaw Y
- Yeshitila YG
- Yilma MT
- Yip P
- Yonemoto N
- Yosef T
- Younis MZ
- Yousuf AY
- Yu C
- Yu Y
- Yuce D
- Zafar S
- Zaidi SS
- Zaki L
- Zaki MES
- Zakzuk J
- Zamanian M
- Zar HJ
- Zastrozhin MS
- Zastrozhina A
- Zelellw DA
- Zhang Y
- Zhang Z-J
- Zhao X-JG
- Zodpey S
- Zuniga YMH
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2021
- Field of study
Exclusive breastfeeding (EBF)-giving infants only breast-milk for the first 6 months of life-is a component of optimal breastfeeding practices effective in preventing child morbidity and mortality. EBF practices are known to vary by population and comparable subnational estimates of prevalence and progress across low- and middle-income countries (LMICs) are required for planning policy and interventions. Here we present a geospatial analysis of EBF prevalence estimates from 2000 to 2018 across 94 LMICs mapped to policy-relevant administrative units (for example, districts), quantify subnational inequalities and their changes over time, and estimate probabilities of meeting the World Health Organization's Global Nutrition Target (WHO GNT) of â„70% EBF prevalence by 2030. While six LMICs are projected to meet the WHO GNT of â„70% EBF prevalence at a national scale, only three are predicted to meet the target in all their district-level units by 2030.This work was primarily supported by grant no. OPP1132415 from the Bill & Melinda Gates Foundation. Co-authors used by the Bill & Melinda Gates Foundation (E.G.P. and R.R.3) provided feedback on initial maps and drafts of this manuscript. L.G.A. has received support from Coordenação de Aperfeiçoamento de Pessoal de NĂvel Superior, Brasil (CAPES), CĂłdigo de Financiamento 001 and Conselho Nacional de Desenvolvimento CientĂfico e TecnolĂłgico (CNPq) (grant nos. 404710/2018-2 and 310797/2019-5). O.O.Adetokunboh acknowledges the National Research Foundation, Department of Science and Innovation and South African Centre for Epidemiological Modelling and Analysis. M.Ausloos, A.Pana and C.H. are partially supported by a grant from the Romanian National Authority for Scientific Research and Innovation, CNDS-UEFISCDI, project no. PN-III-P4-ID-PCCF-2016-0084. P.C.B. would like to acknowledge the support of F. Alam and A. Hussain. T.W.B. was supported by the Alexander von Humboldt Foundation through the Alexander von Humboldt Professor award, funded by the German Federal Ministry of Education and Research. K.Deribe is supported by the Wellcome Trust (grant no. 201900/Z/16/Z) as part of his international intermediate fellowship. C.H. and A.Pana are partially supported by a grant of the Romanian National Authority for Scientific Research and Innovation, CNDS-UEFISCDI, project no. PN-III-P2-2.1-SOL-2020-2-0351. B.Hwang is partially supported by China Medical University (CMU109-MF-63), Taichung, Taiwan. M.Khan acknowledges Jatiya Kabi Kazi Nazrul Islam University for their support. A.M.K. acknowledges the other collaborators and the corresponding author. Y.K. was supported by the Research Management Centre, Xiamen University Malaysia (grant no. XMUMRF/2020-C6/ITM/0004). K.Krishan is supported by a DST PURSE grant and UGC Centre of Advanced Study (CAS II) awarded to the Department of Anthropology, Panjab University, Chandigarh, India. M.Kumar would like to acknowledge FIC/NIH K43 TW010716-03. I.L. is a member of the Sistema Nacional de InvestigaciĂłn (SNI), which is supported by the SecretarĂa Nacional de Ciencia, TecnologĂa e InnovaciĂłn (SENACYT), PanamĂĄ. M.L. was supported by China Medical University, Taiwan (CMU109-N-22 and CMU109-MF-118). W.M. is currently a programme analyst in Population and Development at the United Nations Population Fund (UNFPA) Country Office in Peru, which does not necessarily endorses this study. D.E.N. acknowledges Cochrane South Africa, South African Medical Research Council. G.C.P. is supported by an NHMRC research fellowship. P.Rathi acknowledges support from Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, India. Ramu Rawat acknowledges the support of the GBD Secretariat for supporting the reviewing and collaboration of this paper. B.R. acknowledges support from Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal. A.Ribeiro was supported by National Funds through FCT, under the programme of âStimulus of Scientific EmploymentâIndividual Supportâ within the contract no. info:eu-repo/grantAgreement/FCT/CEEC IND 2018/CEECIND/02386/2018/CP1538/CT0001/PT. S.Sajadi acknowledges colleagues at Global Burden of Diseases and Local Burden of Disease. A.M.S. acknowledges the support from the Egyptian Fulbright Mission Program. F.S. was supported by the Shenzhen Science and Technology Program (grant no. KQTD20190929172835662). A.Sheikh is supported by Health Data Research UK. B.K.S. acknowledges Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal for all the academic support. B.U. acknowledges support from Manipal Academy of Higher Education, Manipal. C.S.W. is supported by the South African Medical Research Council. Y.Z. was supported by Science and Technology Research Project of Hubei Provincial Department of Education (grant no. Q20201104) and Outstanding Young and Middle-aged Technology Innovation Team Project of Hubei Provincial Department of Education (grant no. T2020003). The funders of the study had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript. The corresponding author had full access to all the data in the study and had final responsibility for the decision to submit for publication. All maps presented in this study are generated by the authors and no permissions are required to publish them
Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries.
- Author
- Ab Majid MA
- Ab Rahman AS
- Ab Rahman R
- Abayasinghe C
- Abbott T
- Abdullah NH
- Abdur-Rahman L
- Abeloos J
- Abernethy C
- Abidin UN
- Abrunhosa A
- Absar M
- Adam S
- Adams D
- Adams G
- Adamson M
- Adekola O
- Adelaja Y
- Ademola A
- Adenekan A
- Adenike O
- Adeolu AA
- Adetoye A
- Adewale B
- Adigun T
- Adolfsson A
- Aflori L
- Africander C
- Afshari A
- Agarwal V
- Agodirin O
- Aguero Vera M
- Aguzzoli C
- Ahmad A
- Ahmad N
- Ahmad T
- Ahmad T
- Ahmad Y
- Ahmed A
- Ahmed J
- Ai Y
- Aignatoaie M
- Aimoniotou-Georgiou E
- Akanmu O
- Akerman N
- Akinwale M
- Akring I
- Al 'Amri K
- Al Anizi M
- Al hussaini S
- Al-Soudaine Y
- Aladin H
- Alagbe-Briggs O
- Alaman Laguarda G
- Albaj S
- Alcock D
- Alcock L
- Aldecoa C
- Aldecoa C
- Aleixo FB
- Alexander H
- Alexander M
- Alexander-Sefre F
- Alherz F
- Ali H
- Ali M
- Ali S
- Alias A
- Alias AH
- Alias RLR
- Alit MA
- Allen S
- Allen SJ
- Allison J
- Alloj C
- Allorto NL
- Allsop J
- Almeida W
- Alonso E
- Alphonsus C
- Alvares D
- Alves MJ
- Amador JCB
- Ameer Y
- Amendola CP
- Ami N
- Amstrup-Hansen L
- Anagnou A
- Andersen C
- Anderson C
- Anderson C
- Anderson F
- Anderson P
- Andreadaki E
- Andreou A
- Andreou P
- Andrew A
- Andrews E
- Angermair S
- Angus K
- Anillo V
- Antal O
- Antill P
- Antoniadou E
- Antonina W
- Apagaki E
- Apostolou K
- Applewhaite C
- Aquino LPG
- Ar P
- Arawwawala D
- Ardern D
- Argue R
- Arkalaki E
- Armaganidis A
- Armstrong J
- Armstrong R
- Arnaoutoglou C
- Arnaoutoglou E
- Arnold G
- Arrandale L
- Arrich J
- Arrigo M
- Arshad H
- Arshad MA
- Arumugam S
- Arustei M
- Arvaniti K
- Arya A
- Arya S
- Asimakos A
- Asudo F
- Athanasakis E
- Atiku M
- Attrill E
- Attwood C
- Auer P
- Avidan M
- Avila Sanchez FJ
- Avila EJD
- Avis J
- Awad H
- Axioti E
- Ayyaz H
- Azam UAA
- Azambuja P
- Azevedo C
- Aziz FZ
- Baas P
- Baghirzada L
- Bai H-P
- Bai Y
- Baillie S
- Baines D
- Baio TH
- Bairaktari A
- Baker G
- Baker K-A
- Baker P
- Balain B
- Balaji P
- Balajonda N
- Balanescu A
- Balasubramaniam M
- Baldisserotto S
- Baldwin J
- Baldwin M
- Balfoussia D
- Bali C
- Bandeira ME
- Banerjee R
- Bankewitz C
- Banner-Goodspeed V
- Bao Q
- Barcraft-Barnes H
- Barneto L
- Barnett A
- Baroselli A
- Barraclough J
- Barras J-P
- Barrett S
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- Basanth S
- Batchelor N
- Bateman B
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- Batista HD
- Bauchmuller K
- Bauer M
- Baumgarten G
- Baxter L
- Beaton C
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- Beavis V
- Bechan S
- Bejia T
- Belciu I
- Belda MT
- Bell G
- Bell R
- Bell S
- Bellandi M
- Bello J
- Beloeil H
- Belskiy V
- Ben-Menachem E
- Benavent P
- Benevento A
- Bengeri S
- Bennett C
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- Bennett R
- Bennett V
- Bentley C
- Beretta L
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- Bernard A
- Berntsen E
- Bertram W
- Bester D
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- Bettega F
- Bettinelli A
- Bhardwaj N
- Bhatia K
- Bhula C
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- Bidd H
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- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2016
- Field of study
BACKGROUND: As global initiatives increase patient access to surgical treatments, there remains a need to understand the adverse effects of surgery and define appropriate levels of perioperative care. METHODS: We designed a prospective international 7-day cohort study of outcomes following elective adult inpatient surgery in 27 countries. The primary outcome was in-hospital complications. Secondary outcomes were death following a complication (failure to rescue) and death in hospital. Process measures were admission to critical care immediately after surgery or to treat a complication and duration of hospital stay. A single definition of critical care was used for all countries. RESULTS: A total of 474 hospitals in 19 high-, 7 middle- and 1 low-income country were included in the primary analysis. Data included 44Â 814 patients with a median hospital stay of 4 (range 2-7) days. A total of 7508 patients (16.8%) developed one or more postoperative complication and 207 died (0.5%). The overall mortality among patients who developed complications was 2.8%. Mortality following complications ranged from 2.4% for pulmonary embolism to 43.9% for cardiac arrest. A total of 4360 (9.7%) patients were admitted to a critical care unit as routine immediately after surgery, of whom 2198 (50.4%) developed a complication, with 105 (2.4%) deaths. A total of 1233 patients (16.4%) were admitted to a critical care unit to treat complications, with 119 (9.7%) deaths. Despite lower baseline risk, outcomes were similar in low- and middle-income compared with high-income countries. CONCLUSIONS: Poor patient outcomes are common after inpatient surgery. Global initiatives to increase access to surgical treatments should also address the need for safe perioperative care. STUDY REGISTRATION: ISRCTN5181700
Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study
- Author
- Abantanga FA
- Abatli SJ
- Abbas W
- Abbo O
- Abd Elmenam M
- Abd Razak RB
- Abdelbaqi R
- Abdelhady DS
- Abdelhafez MOM
- Abdelhamid SS
- Abdelmaksoud S
- Abdelmoumen R
- Abdelmutalib F
- Abdul-Mumin A
- Abduljawad FM
- Abdullah F
- Abdulraheem N
- Abdulrahman A
- Abdulsalam MA
- Abdunomonovich DA
- Abib SDCV
- Aboelela A
- Abouheba M
- Abrahamsson K
- Abu Ajwa AE
- Abu Al-saleem HSH
- Abu Alamrain AA
- Abu Bakar AH
- Abu Farha MS
- Abu Jamie N
- Abu Jamie YMK
- Abu Jayyab M
- Abu Mayaleh A
- Abu Shiha E
- Abu Za'nouneh FJ
- Abu-Nejmah F
- Abuajaila A
- Abuattaya AA
- Abubakar AM
- Abueideh A
- Abuhayyeh HA
- Abuhlega MA
- Abukhalaf S
- Abumunshar AA
- Acuna G
- Adams S
- Adamu S
- Adanan MFSBM
- Adawi I
- Adawi S
- Adawy A
- Ade-Ajayi N
- Adegboyega R
- Ademuyiwa A
- Adesanya O
- Adhiwidjaja CF
- Adofo-Ansong N
- Agboola TH
- Agelebe E
- Aguiar AA
- Aguilar FA
- Aguirre-Lopez P
- Agulham MA
- Ahmad H
- Ahmad ZAH
- Ahmed H
- Ahmed MA
- Ajai OT
- Ajao EA
- Ajiboye OS
- Ajrami Y
- Akan ME
- Akhbari M
- Akhter N
- Akova F
- Al Dammagh NM
- Al Hussein S
- Al Massry NA
- Al Quran TM
- Al-Attar HM
- Al-Halbouni L
- Al-Mamun A
- Al-Mayoof AF
- Al-Momani HM
- Al-Mouakeh A
- Al-Rayyes M
- Al-Salhi AA
- Al-Shwaikh SH
- Al-Slaibi I
- Al-Taher RN
- Al-Taher RN
- Al-Tammam H
- Alakaloko F
- Alattas K
- Alberto C
- Albozidi A
- Alcantara E
- Aldirawi MAM
- Alebbini MM
- Alfoghi M
- Algabri HNO
- Alglaib MM
- Alhamid A
- Alhamid A
- Alhassan P
- Ali H
- Ali KO
- Ali L
- Ali M
- Alijla S
- Alijla SS
- Aliwisat AH
- Aljaboo H
- Aljadidi WOFS
- Aljarad Z
- Alkali YS
- Alkareem RMA
- Almada SA
- Almadhoun W
- Almasri M
- Almeida G
- Almengar I
- Almohamady H
- Almosaibli M
- Almusleh TFH
- Alnaeri A
- Alnahhal K
- Alonso V
- Alosta HM
- Alqarajeh F
- Alqor MOI
- Alsaadi NN
- Alsaggaf A
- Alsaied A
- Alser M
- Alser OH
- Alshaikhkhalil HAA
- Alshehri A
- Altamirano PR
- Altaweel A
- Altin M
- Altokhais T
- Altomi M
- Alturki F
- Alva LRC
- Alvarez JR
- Alwadia SMS
- Alwaggaa NA
- Alzamari AAM
- Alzeer AMS
- Alzerei ST
- Alzraikat SH
- Alzubair A
- Alzughayyar TZ
- Amad M
- Amado F
- Amaechi C
- Amah CC
- Amarin JZ
- Amarin M
- Ambriz-Gonzalez G
- Ameh E
- Amoabin AA
- Anatole N
- Anatole NK
- Anaya F
- Anaya WB
- Andrade J
- Andreussi L
- Annajjar MH
- Anntinea J
- Antunes A
- Antunez-Mora A
- Anyomih TTK
- Anzelewicz S
- Appeadu-Mensah W
- Arabiat E
- Arafa MA
- Arafat H
- Aragao L
- Arancibia JAC
- Arar AS
- Arauco J
- Arbab H
- Arboleda J
- Aremo A
- Argomedo MRO
- Arnadottir H
- Arnaud AP
- Arnold M
- Arnoletto LB
- Arrmali S
- Arrmalli LA
- Arshad M
- Arthur F
- Arul S
- Ashour DA
- Ashour YS
- Aslan Y
- Aspirot A
- Assi A
- Assi MAF
- Astudillo M
- Atatri YYM
- Atta A
- Attia AM
- Aucatoma FC
- Augusto MLDS
- Avila DC
- Avile R
- Avolio L
- Awad H
- Aydin E
- Aykut M
- Aziz DAA
- Ba'baa' B
- Badr H
- Baertschiger R
- Bagbio D
- Bah A
- Bai Q
- Bai YZ
- Baistrocchi V
- Baker W
- Ballah AM
- Ballouhey Q
- Balousha AG
- Bamanga A
- Baniowda MAM
- Bao X
- Barauskas V
- Barbosa PR
- Barcelos FZ
- Baron JDJC
- Barreto JJS
- Barros BS
- Baseggio N
- Bashir F
- Bashir MK
- Bataineh ZA
- Batal MM
- Bazozi HM
- Beasley S
- Becker K
- Belesa FDA
- Beloy IC
- Beltran NS
- Ben Enbaya M
- Benaskeur Y-I
- Benavente CM
- Beres A
- Berkova K
- Bernaus M
- Berzanskis M
- Beshtawi DMS
- Besir A
- Bianchin E
- Bibas F
- Biber E
- bin Abdullah MY
- Bin Amjad M
- bin Bujarimin AS
- bin Hassan MR
- Bin Othman MY
- bin Zahari Z
- bin Zarwawi AZ
- Bischoff C
- Blain OE
- Blanc T
- Blanchet EB
- Blazquez-Gomez E
- Blom MD
- Bode C
- Bonnard A
- Boonthai A
- Borbonet D
- Borges CG
- Bouhadiba N
- Bowder A
- Bradshaw K
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- Brahmamdam P
- Bravo MN
- Bravo MRDT
- Brenner NK
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- Broch A
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- Bruxel CL
- Bsisu I
- Bucaram E
- Burgos CM
- Burks SS
- Burns K
- Butler M
- Bvulani B
- Caamal LJ
- Cai D
- Calancea C
- Calderon LO
- Calistus N
- Calle CS
- Cama J
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- Camamra K
- Cameron F
- Camp L
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- Caouette-Laberge L
- Carbajal LF
- Carloni ICS
- Carrasco AL
- Carrasco-Ortega C
- Carrillo I
- Casado FT
- Caseb P
- Casquero V
- Castaneda FDMD
- Castillo MN
- Cavaiuolo S
- Cekic B
- Celik M
- Centen SV
- Cepeda R
- Cesur IB
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- Chang J
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- Chaudary AR
- Chaudhry MA
- Chauhan N
- Chen J
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- Chen R
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- Chipalavela RF
- Chipana CLA
- Chiriboga E
- Chiroque CM
- Chitiavi SW
- Chitnis M
- Cho SH
- Choo CSC
- Chukwu I
- Chukwuemeka AL-J
- Chung JH
- Cino EL
- Cletus C
- Coghill G
- Collins N
- Comert HSY
- Contreras CS
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- Cordonnier A
- Cordova KH
- Cornelli F
- Cornwall H
- Corona MQ
- Correa A
- Correa C
- Cortez LFG
- Cosoreanu V
- Costa EC
- Costas-Chavarri A
- Cripovich A
- Cruzado GJS
- Cunningham A
- Cury EK
- Czauderna P
- da Cunha AG
- da Silva EAD
- da Silva JAN
- da Silva KI
- Dagilyte R
- Daher AP
- Dahman NBH
- Dalek NFRA
- Dallegre MB
- Dalloul H
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- Dania B
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- Darwish A
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- de Almeida TL
- de Andrade SO
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- de Fraga JCS
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- De La Cruz RR
- de Oliveira DF
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- Defert C
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- Delforge X
- Dendusic N
- Derbew M
- Derks T
- Deya C
- Deyab A
- Deyl RT
- Di Siervi O
- Dias AIBDS
- Dieudonne L
- Dimatatac DM
- Djordjevic I
- do Nascimento SD
- Dogar S
- Doheim MF
- Dominguez D
- Dominguez MA
- dos Santos CS
- dos Santos MSF
- Dosselman LJ
- Douiri A
- Drah W
- Dube AM
- Duchesne C
- Duggan E
- Dure C
- Ebeido A
- Echegaray MD
- Egbuchulem IK
- Ejinkeonye EC
- Ekenze SO
- Ekwunife OH
- El Tallaa MA
- El-Ghazaly M
- Elassall GMH
- Elayeb A
- Elebute OA
- Elewaily M
- Elfiky M
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- Espinoza PP
- Essa TM
- Essamilghi KAM
- Ezidiegwu US
- Ezomike UO
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- Ferdousi T
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- Ferreira JL
- Ferreira MDSS
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- Gadepalli S
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- Garcia I
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- Garnier H
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- Gavrila B
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- Gee O
- Gerus S
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- Ghorab IA
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- Guinsburg R
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- Hinojosa AS
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- Hussain SR
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- Kayibanda E
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- Quiroz NH
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- Publication venue
- ELSEVIER SCIENCE INC
- Publication date
- 24/07/2021
- Field of study
Background: Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. // Methods: We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung's disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. // Findings: We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung's disease) from 264 hospitals (89 in high-income countries, 166 in middle-income countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36â39) and median bodyweight at presentation was 2·8 kg (2·3â3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in low-income countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; pâ€0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88â4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59â2·79], p<0·0001), sepsis at presentation (1·20 [1·04â1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4â5 vs ASA 1â2, 1·82 [1·40â2·35], p<0·0001; ASA 3 vs ASA 1â2, 1·58, [1·30â1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02â1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41â2·71], p=0·0001; parenteral nutrition 1·35, [1·05â1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47â0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50â0·86], p=0·0024) or percutaneous central line (0·69 [0·48â1·00], p=0·049) were associated with lower mortality. // Interpretation: Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between low-income, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030
Search for strongly interacting massive particles generating trackless jets in proton-proton collisions at s = 13 TeV
- Author
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- Ăsterberg K
- Ăzçelik Ă
- Ć irokĂœ J
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
A search for dark matter in the form of strongly interacting massive particles (SIMPs) using the CMS detector at the LHC is presented. The SIMPs would be produced in pairs that manifest themselves as pairs of jets without tracks. The energy fraction of jets carried by charged particles is used as a key discriminator to suppress efficiently the large multijet background, and the remaining background is estimated directly from data. The search is performed using proton-proton collision data corresponding to an integrated luminosity of 16.1 fb - 1 , collected with the CMS detector in 2016. No significant excess of events is observed above the expected background. For the simplified dark matter model under consideration, SIMPs with masses up to 100 GeV are excluded and further sensitivity is explored towards higher masses
Measurement of the inclusive and differential Higgs boson production cross sections in the decay mode to a pair of Ï Leptons in pp collisions at sqrt[s]=13ââTeV
- Author
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- Aarup Petersen H
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- Zorbilmez C
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- Zumerle G
- Zuo X
- Zuolo D
- Zygala L
- Ălvarez FernĂĄndez A
- Ăzçelik Ă
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2022
- Field of study
Measurements of the inclusive and differential fiducial cross sections of the Higgs boson are presented, using the Ï lepton decay channel. The differential cross sections are measured as functions of the Higgs boson transverse momentum, jet multiplicity, and transverse momentum of the leading jet in the event, if any. The analysis is performed using proton-proton collision data collected with the CMS detector at the LHC at a center-of-mass energy of 13ââTeV and corresponding to an integrated luminosity of 138ââfb^{-1}. These are the first differential measurements of the Higgs boson cross section in the final state of two Ï leptons. In final states with a large jet multiplicity or with a Lorentz-boosted Higgs boson, these measurements constitute a significant improvement over measurements performed in other final states
Search for Higgs Boson Pair Production in the Four b Quark Final State in Proton-Proton Collisions at root s=13 TeV
- Author
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- Zorbilmez C
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- Zuo X
- Zuolo D
- Zygala L
- Ălvarez CR
- Ăzçelik Ă
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Search for invisible decays of the Higgs boson produced via vector boson fusion in proton-proton collisions at root s=13 TeV
- Author
- Aarrestad T
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdelalim A
- Abdullin S
- Abercrombie D
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- Acharya H
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- Yuan L
- Yuan S
- Yuldashev B
- Yumiceva F
- Yzquierdo AP
- Zabi A
- Zacharopoulou A
- Zahid S
- Zaleski S
- Zalewski P
- Zanetti M
- Zarubin A
- Zarucki M
- Zecchinelli A
- Zeinali M
- Zeuner W
- Zghiche A
- Zhang F
- Zhang H
- Zhang J
- Zhang L
- Zhang W
- Zhang Y
- Zhang Z
- Zhao J
- Zhizhin I
- Zhokin A
- Zhu R
- Ziemons T
- Zipper N
- Zoi I
- Zolkapli Z
- Zorbakir I
- Zorbilmez C
- Zotto P
- Zotz A
- Zou D
- Zou R
- Zucchetta A
- Zumerle G
- Zuo X
- Zuolo D
- Zygala L
- Ălvarez CR
- Ăzçelik Ă
- Publication venue
- Publication date
- 01/01/2022
- Field of study
- âŠ