85 research outputs found
Differential Proteomic Analysis of Human Erythroblasts Undergoing Apoptosis Induced by Epo-Withdrawal
- Author
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2012
- Field of study
The availability of Erythropoietin (Epo) is essential for the survival of erythroid progenitors. Here we study the effects of Epo removal on primary human erythroblasts grown from peripheral blood CD34+ cells. The erythroblasts died rapidly from apoptosis, even in the presence of SCF, and within 24 hours of Epo withdrawal 60% of the cells were Annexin V positive. Other classical hallmarks of apoptosis were also observed, including cytochrome c release into the cytosol, loss of mitochondrial membrane potential, Bax translocation to the mitochondria and caspase activation. We adopted a 2D DIGE approach to compare the proteomes of erythroblasts maintained for 12 hours in the presence or absence of Epo. Proteomic comparisons demonstrated significant and reproducible alterations in the abundance of proteins between the two growth conditions, with 18 and 31 proteins exhibiting altered abundance in presence or absence of Epo, respectively. We observed that Epo withdrawal induced the proteolysis of the multi-functional proteins Hsp90 alpha, Hsp90 beta, SET, 14-3-3 beta, 14-3-3 gamma, 14-3-3 epsilon, and RPSA, thereby targeting multiple signaling pathways and cellular processes simultaneously. We also observed that 14 proteins were differentially phosphorylated and confirmed the phosphorylation of the Hsp90 alpha and Hsp90 beta proteolytic fragments in apoptotic cells using Nano LC mass spectrometry. Our analysis of the global changes occurring in the proteome of primary human erythroblasts in response to Epo removal has increased the repertoire of proteins affected by Epo withdrawal and identified proteins whose aberrant regulation may contribute to ineffective erythropoiesis
GIL: a red cell antigen of very high frequency
- Author
- Publication venue
- 'Exeley, Inc.'
- Publication date
- Field of study
Early mortality and primary causes of death in mothers of children with ID or ASD: a retrospective cohort study
- Author
- A Corrice
- A Kouvonen
- A Richdale
- B Baker
- B Petterson
- C Bigby
- C Thiel
- D Lawrence
- D Lawrence
- D Norlin
- E Calle
- E Sen
- Geoff Hammond
- H Bourke-Taylor
- H Eoh
- H Leonard
- H Leonard
- Helen Leonard
- J Caldwell
- J Daniels
- J Daniels
- J Dumas
- J Finsterer
- J Sanders
- J Smith
- Jenny Bourke
- Jenny Fairthorne
- K Anderson
- K Bjartveit
- Katsuaki Suzuki
- L Abbeduto
- M Baker-Ericzén
- M Olsson
- M Polimeni
- M Sawyer
- M Watt
- M Yeargin-Allsopp
- P Black
- Peter Jacoby
- R Hagerman
- R Hodapp
- R Webster
- S Rasmussen
- S Rizk
- Y Chida
- Y Takahashi
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 23/12/2014
- Field of study
INTRODUCTION: Mothers of children with intellectual disability or autism spectrum disorder (ASD) have poorer health than other mothers. Yet no research has explored whether this poorer health is reflected in mortality rates or whether certain causes of death are more likely. We aimed to calculate the hazard ratios for death and for the primary causes of death in mothers of children with intellectual disability or ASD compared to other mothers. METHODS: The study population comprised all mothers of live-born children in Western Australia from 1983-2005. We accessed state-wide databases which enabled us to link socio-demographic details, birth dates, diagnoses of intellectual disability or ASD in the children and dates and causes of death for all mothers who had died prior to 2011. Using Cox Regression with death by any cause and death by each of the three primary causes as the event of interest, we calculated hazard ratios for death for mothers of children intellectual disability or ASD compared to other mothers. RESULTS AND DISCUSSION: During the study period, mothers of children with intellectual disability or ASD had more than twice the risk of death. Mothers of children with intellectual disability were 40% more likely to die of cancer; 150% more likely to die of cardiovascular disease and nearly 200% more likely to die from misadventure than other mothers. Due to small numbers, only hazard ratios for cancer were calculated for mothers of children with ASD. These mothers were about 50% more likely to die from cancer than other mothers. Possible causes and implications of our results are discussed. CONCLUSION: Similar studies, pooling data from registries elsewhere, would improve our understanding of factors increasing the mortality of mothers of children with intellectual disability or ASD. This would allow the implementation of informed services and interventions to improve these mothers' longevity
Transmission of molecularly undetectable circulating parasite clones leads to high infection complexity in mosquitoes post feeding.
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- 05/05/2018
- Field of study
Plasmodium falciparum malaria infections often comprise multiple distinct parasite clones. Few datasets have directly assessed infection complexity in humans and mosquitoes they infect. Examining parasites using molecular tools may provide insights into the selective transmissibility of isolates. Using capillary electrophoresis genotyping and next generation amplicon sequencing, we analysed complexity of parasite infections in human blood and in the midguts of mosquitoes that became infected in membrane feeding experiments using the same blood material in two West African settings. Median numbers of clones in humans and mosquitoes were higher in samples from Burkina Faso (4.5, interquartile range 2-8 for humans; and 2, interquartile range 1-3 for mosquitoes) than in The Gambia (2, interquartile range 1-3 and 1, interquartile range 1-3, for humans and mosquitoes, respectively). Whilst the median number of clones was commonly higher in human blood samples, not all transmitted alleles were detectable in the human peripheral blood. In both study sample sets, additional parasite alleles were identified in mosquitoes compared with the matched human samples (10-88.9% of all clones/feeding assay, n = 73 feeding assays). The results are likely due to preferential amplification of the most abundant clones in peripheral blood but confirm the presence of low density clones that produce transmissible sexual stage parasites
The First Post-Kepler Brightness Dips of KIC 8462852
- Author
- Alonso Roi
- Ammerman Alex
- Armstrong David
- Asensio Ramos A.
- Aznar Carbo Miguel
- Barkaoui K.
- Beatty Thomas G.
- Benkhaldoun Z.
- Benni Paul
- Bentley Rory O.
- Berdyugin Andrei
- Berdyugina Svetlana
- Bergeron Serge
- Bieryla Allyson
- Blain Michaela G.
- Bodman Eva H. L.
- Boucher Anne
- Boyajian Tabetha S.
- Bradley Mark
- Brincat Stephen M.
- Brink Thomas G.
- Briol John
- Brown David J. A.
- Budaj J.
- Burdanov Artem
- Cale B.
- Capetillo Blanco Alicia
- Castillo García R.
- Clark Wendy J.
- Clayton Geoffrey C.
- Clem James L.
- Coker Phillip H.
- Cook Evan M.
- Copperwheat Chris M.
- Cseh B.
- Curtis J. L.
- Cutri R. M.
- Cynamon C. H.
- Daniels Alex J.
- Davenport James R. A.
- de Jaeger Thomas
- De Lorenzo Roberto
- Deeg Hans J.
- Desrosiers Jean-Bruno
- Dolan John
- Dowhos D. J.
- Dubois Franky
- Durkee R.
- Dvorak Shawn
- Easley Lynn
- Edwards N.
- Ellis Tyler G.
- Erdelyi Emery
- Ertel Steve
- Farfán Rafael G.
- Farihi J.
- Filippenko Alexei V.
- Foxell Emma
- Gandolfi Davide
- Garcia Faustino
- Giddens F.
- Gillon Michaël
- González Hernández J. I.
- González-Carballo Juan-Luis
- González-Fernández C.
- Graham Keith A.
- Greene Kenton A.
- Gregorio J.
- Hallakoun Na Ama
- Hanyecz Ottó
- Harp G. R.
- Henry Gregory W.
- Herrero E.
- Hildbold Caleb F.
- Hinzel D.
- Holgado G.
- Ignácz Bernadett
- Ilyin Ilya
- Ivanov Valentin D.
- Jehin Emmanuel
- Jermak Helen E.
- Johnston Steve
- Kafka S.
- Kalup Csilla
- Kardasis Emmanuel
- Kaspi Shai
- Kennedy Grant M.
- Kessler Dennis
- Kiefer F.
- Kielty C. L.
- Kiiskinen H.
- Killestein T. L.
- King Ronald A.
- Kollar V.
- Korhonen H.
- Kotnik C.
- Kriskovics Levente
- Krumm Nathan
- Krushinsky Vadim
- Kundra E.
- Könyves-Tóth Réka
- Lachapelle Francois-Rene
- LaCourse D.
- Lake P.
- Lam Kristine
- Lamb Gavin P.
- Lane Dave
- Lau Marie Wingyee
- Lewin Pablo
- Lintott Chris
- Lisse Carey
- Logie Ludwig
- Longeard Nicolas
- Lopez Villanueva M.
- Mainzer A.
- Malo Lison
- Maloney Chris
- Mann A.
- Mantero A.
- Marchant Jon
- Marengo Massimo
- Martínez González M. J.
- Masiero Joseph R.
- Mauerhan Jon C.
- McCormac James
- McNeely Aaron
- Meng Huan Y. A.
- Miller Mike
- Molnar Lawrence A.
- Morales J. C.
- Morris Brett M.
- Muterspaugh Matthew W.
- Nespral David
- Nugent C. R.
- Nugent Katherine M.
- O'Keeffe Derek
- O'Meara John M.
- Odasso A.
- Oksanen A.
- Ordasi András
- Osborn Hugh
- Ott John J.
- Parks J. R.
- Petriew Vance
- Pickard R.
- Plavchan P.
- Pollacco Don
- Pozo Nuñez F.
- Pozuelos Romero Francisco José
- Pál András
- Rau Steve
- Redfield Seth
- Relles Howard
- Ribas Ignasi
- Richards Jon
- Rodriguez Perez Diego
- Saario Joonas L. O.
- Safron Emily J.
- Sallai J. Martin
- Schaefer Bradley E.
- Schumer Clea F.
- Schwartzendruber Madison
- Siegel Michael H.
- Siemion Andrew P. V.
- Simmons Brooke D.
- Simon Joshua D.
- Simón-Díaz S.
- Sitko Michael L.
- Socas-Navarro Hector
- Starkey Donn
- Steele Iain A.
- Stone Geoff
- Strassmeier Klaus G.
- Street R. A.
- Sullivan Tricia
- Suomela J.
- Swift J. J.
- Szabó Gyula M.
- Szabó Róbert
- Szakáts Róbert
- Szalai Tamás
- Sárneczky Krisztián
- Sódor Á.
- Tanner Angelle M.
- Toledo-Padrón B.
- Tordai Tamás
- Triaud Amaury H. M. J.
- Turner Jake D.
- Ulowetz Joseph H.
- Urbanik Marian
- Vanaverbeke Siegfried
- Vanderburg Andrew
- Vida Krisztián
- Vietje Brad P.
- Vinkó József
- von Braun K.
- Waagen Elizabeth O.
- Walsh Dan
- Watson Christopher A.
- Weir R. C.
- Wenzel Klaus
- Westendorp Plaza C.
- Whit Ludington E.
- Williamson Michael W.
- Wright Jason T.
- Wyatt M. C.
- Zheng Weikang
- Zsidi Gabriella
- Publication venue
- 'American Astronomical Society'
- Publication date
- 01/01/2018
- Field of study
We present a photometric detection of the first brightness dips of the unique variable star KIC 8462852 since the end of the Kepler space mission in 2013 May. Our regular photometric surveillance started in October 2015, and a sequence of dipping began in 2017 May continuing on through the end of 2017, when the star was no longer visible from Earth. We distinguish four main 1-2.5% dips, named "Elsie," "Celeste," "Skara Brae," and "Angkor", which persist on timescales from several days to weeks. Our main results so far are: (i) there are no apparent changes of the stellar spectrum or polarization during the dips; (ii) the multiband photometry of the dips shows differential reddening favoring non-grey extinction. Therefore, our data are inconsistent with dip models that invoke optically thick material, but rather they are in-line with predictions for an occulter consisting primarily of ordinary dust, where much of the material must be optically thin with a size scale <<1um, and may also be consistent with models invoking variations intrinsic to the stellar photosphere. Notably, our data do not place constraints on the color of the longer-term "secular" dimming, which may be caused by independent processes, or probe different regimes of a single process
Professional learning through the collaborative design of problem-solving lessons
- Author
- A McIntyre
- B Doig
- C Fernandez
- C Lewis
- Colin Foster
- DA Schön
- Geoff Wake
- H Daniels
- JW Stigler
- KD Beach
- Malcolm Swan
- National Council of Teachers of Mathematics (NCTM)
- OECD (Organisation for Economic Co-operation and Development)
- P Drijvers
- P Drijvers
- Qualifications and Curriculum Authority
- RJ Boland
- S Kindon
- SF Akkerman
- SL Star
- W-M Roth
- Y Engeström
- Y Engeström
- Y Engeström
- Y Shimizu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Robust estimation of bacterial cell count from optical density
- Author
- Aarnio Tiu
- Aaron Leow Chung Yong
- Abbas Anser
- Abduraimova Aiganym
- Abraham Doris
- Acar Beliz Leyla
- Acosta Joaquin
- Adler Nina
- Adulyanukosol Natthawut
- Agena Ejouan
- Agena Ethan
- Aggarwal Priya
- Aguirre Adriana Lizeth Rubio
- Ahlgren Christopher
- Ahuja Janvi
- Aizik Dror
- Akbary Mina
- Akinfenwa Akinwumi
- Akingbesote Ngozi D.
- Akova Umut
- Aldo Ferdinan
- Alexopoulos Ioannis
- Allen Lucy
- Alonso Alejandro
- Altarawneh Dina
- Alvarado Andres Benjamin Sanchez
- Ambre Sanika
- Ameziane Annissa
- Amheine Khadija
- Amin Ihya Fakhrurizal
- Amir Sayeda Sakina
- Amstel Chiel van
- An Yongyan
- Anand Nithishwer Mouroug
- Ananthakrishnan Sathvik
- Anderson Karl
- Angel Sagi
- Annem Vidhya
- Anson Chung Tsun Ho
- Anwar Mariam
- Appel Alana
- Araya Lucas
- Armstrong Alexander
- Arora Neha
- Arora Vasu
- Arruda Beck
- Ashwin F Amal Jude
- Astapenka Artur
- Astles Ben
- Astorino Gabe
- Aubry Celine
- Avileli Rebecca
- Azad Mahnaz Sabeta
- Babar Rehmat
- Babu Priyanka
- Badalli Turan
- Badash Lior
- Baichman-Kass Amichai
- Baldwin Geoff S.
- Baltensperger Oliver Andreas
- Bao Guanke
- Bao Minyue
- Baronaite Ugne
- Barrat Leon Michael
- Barrington Seth
- Barshap Alon
- Bartzoka Natalia
- Basu Anubhav
- Basulto Cynthia
- Bath Scott
- Battina Rohith
- Bauersachs Daniel
- Beal Jacob
- Beale Renee
- Beard Eleanor
- Beck Selina
- Becker Evan
- Benavides Samantha Ayde Pena
- Bennis Nicole
- Bete Anna
- Bhatt Darshak
- Bhowmick Shilpa
- Bian Weixin
- Bijman Eline Yafele
- Bindt Felix
- Blas Karla Soto
- Bo Tang
- Boada Yadira
- Boer Meine
- Bohner Ariel
- Borovko Irina
- Bott Amie
- Bouwmeester Susan
- Bowman Kyle
- Boxem Mike
- Boxuan Cheng
- Boyce Kira
- Boyer Jess
- Brasas Valentas
- Brewer Mathew
- Briand William
- Brink Matilda
- Browne Emily
- Buckley-Taylor Russell
- Budhan Stephanie
- Buller Lisa
- Burckhardt Nele
- Burgland Zachary
- Burns Frank
- Burridge Matt
- Burud Hanna Nedreberg
- Buson Felipe Xavier
- Butterfield Tom
- Byagathvalli Gaurav
- Byatt Gabriel
- Byun Sumin
- Caballero Amalia
- Cai Fu
- Cai Niangui
- Caldwell Sarah
- Camacho Yazmin
- Camille Monteil
- Campbell Robert
- Cao Qinhao
- Cao Yixin
- Cao Yuze
- Carrillo Leo
- Carter Jonah
- Casas Alexis
- Castillo Nora Esther Torres
- Castillo Sandra
- Cave John
- Chai Ruochen
- Chamiec-Case Elizabeth
- Chan Janice
- Chan Yuan-Yao
- Chandramouli Priyanka
- Chang Annabel
- Chang Catherine
- Chang Kevin
- Chang Thomas
- Chang Ting-Chen
- Chang Yu-Ci
- Chapman Tyler
- Chater Dounia
- Chau Anthony
- Chavez Benjamin
- Chavez Francisco
- Chehade Ibrahim
- Chen Carmen
- Chen Chih-Chiang
- Chen Ching-Wei
- Chen Janice
- Chen Junhong
- Chen Junyang
- Chen Junyu
- Chen Pei-Hong
- Chen Ryan
- Chen Weixuan
- Chen Yan
- Chen Yi-Cian
- Chen Yifei
- Chen Zhuoyang
- Cheng Cheng
- Cheng Haolun
- Cheng Hsuan
- Cheng Yu-Hong
- Cheng Yu-Hsuan
- Chenxi Liang
- Cherupalla Arjun
- Chi Jordi
- Chi Shumei
- Chiang Jason
- Chiang Woody
- Ching Lai Tsz
- Ching Lam Kai
- Ching Law Hiu
- Ching Luk Hau
- Chinnathambi Sathivel
- Cho Sungwoo
- Choi Lee Sze
- Choi Youngeun
- Chou Ryan
- Chou Ryan
- Chu Wai Yan
- Chua Yah Tse Sabrina
- Chuang Yi-Chien
- Chulkova Nadezhda
- Chun Cheung Man
- Chun Emily
- Chun Ng Tsz
- Cifuentes Rodrigo Hernandez
- Clapper Jude
- Clapper Jude
- Clark Brittany
- Clemente Borja Sanchez
- Clerc Valerian
- Clodomir Christina
- Coates Ryan
- Cohen Katherine
- Colant Noelle
- Coleman Sarah
- Colgan Cian
- Cone Eli
- Corre Christophe
- Costa Ben
- Cott Rachel Van
- Craw Darilyn
- Crispim Larissa de Souza
- Crone Michael Andrew
- Crooijmans Marjolein
- Crosby Laurel Constanti
- Crowley Peter
- Cruz Frida
- Cubukcu Hande
- Culfogienis Dylan
- Czekster Clarissa
- Dai Leijie
- Dalangin Rochelin
- Daniel Benjamin
- Daniels Lea
- Das Neves Laura
- Das Diptatanu
- Davis Christina
- De Silva Nimaya
- Deb Shalini S.
- Deepak Kumar S.
- Deibel Emilie
- Dejoie Julianne
- Dejoux Alice
- DeKloe Jackson
- Del Toro Mariano
- Delalez Nicolas
- Delgadillo Sabrina
- Delhomme Jean
- Demchuk Aubrey
- Deng Nian Ruei
- Deng Rui
- Denter Jennifer
- Deshmukh-Reeves Ed
- Despres Philippe C.
- Devi Velvizhi
- Dhaliwal Gurpreet
- Diaz Fernanda
- Ding Shizhi
- Ding Yiming
- Ding Zhipeng
- Dingyue Tang
- Dirven Yvette
- Dissmann Jil-Sophie
- Do Stephanie
- Dogra Arushi
- Dominguez Viana Isabel Perez
- Dong Dongyang
- Dong Haitao
- Dong Jason
- Dong Shan
- Dong Shan
- Dong Shan
- Dong Shangzhi
- Dong Shangzhi
- Doyle David
- Doyle Shannon
- Dube Alexandre
- Dubuc Emilien
- Dunstan Izzy
- Dusseaux Theodore A.
- Dvorkin Steve
- Edelmayer Marco
- Ehrenworth Amy
- Eidloth Franziska
- Eijkens Bruno
- Eilers Keno
- El Moubayed Yorgo
- Elcin Evrim
- Elias Noel
- Elikan Max
- Ellermeier Craig
- Elliott Hannah
- Elsa Yeung Hoi Lam
- Emilov Kristian
- Espinoza Diego
- Evans Rhys
- Faidh Mohammed
- Falgenhauer Elisabeth
- Fan Catherine
- Fang Chengzhu
- Fang Choco
- Fang Xiangyi
- Farhi Einan
- Farias Sebastian
- Farny Natalie
- Farny Natalie G.
- Farrell Jennifer
- Fassler Jan
- Faurdal David
- Faustova Ilona
- Feng Xinhua
- Fernandez Cesar Ibrahym Rodriguez
- Fierro Daniela Olono
- Figueroa Ana Cristina
- Figueroa Jose Arnulfo Juarez
- Fikry Clara
- Filzen Rachael
- Fischer Matthew
- Fitzgerald Kevin
- Fitzgerald Liza
- Flores Vinicius
- Foda Asmaa
- Fong Yuhui Deborah
- Forman Victor
- Frank Stefanie
- Frankel Eva
- Freire Paulo J. C.
- Friedman Yonatan
- Frohlich Lisa
- Fu Wenhan
- Fu Yousi
- Fuentes Ernie
- Fulton Leah
- Fung Ip Ning
- Fung Yam Shing
- Gabrielli Jacopo
- Gahagan Maddison
- Gaitt Tobias
- Gaizauskaite Aukse
- Gallegos Isabella
- Gamoneda Diego
- Gandhi Rishi
- Gao Cecily
- Garavito Paula
- Garcia Chrismar
- Garcia David
- Garrido Delia
- Garulli Elisa
- Gaspar Camila
- Gaudi Alex
- Ge Gao
- Ge Yubin
- George Stephan
- Gerard Antoine
- Gershater Markus
- Ghosh Souvik
- Giannopoulos Alexandros Dimitriou
- Giannoula Yvoni
- Gilman Daniel Barber James
- Glockner Eleanor
- Goenka Anushya
- Goetz Marley
- Gogineni Namrata
- Gokul [NO FIRST NAME IN SCOPUS]
- Gonzalo Gonzalo Saiz
- Goodson Michael
- Gopaul Deshmukh
- Gou Yanchen
- Govers Jolijn
- Graaf Floor de
- Grace Tsui Shing Yan
- Graves Daniel
- Grazulyte Inga
- Greenwald Matthew
- Gu Jiajun
- Gu Yiheng
- Gu Yining
- Guadagnino Brett
- Guenther James
- Guerassimoff Lea
- Guo Jintao
- Gupta Shreya
- Guptil Chris
- Guseva Anna
- Ha Jacqueline
- Haddock-Angelli Traci
- Haight Travis
- Hale Mitch
- Hamady Carla
- Han Wang
- Han Weitang
- Handal Paola
- Hanrong Zhu
- Hansen Cecilie
- Hao Junyao
- Hao Mei
- Hao Zhengguo
- Haoran Xu
- Haralsvik Anne Kristin
- Hariyani Imtiyaz
- Hartley Zach
- Hassan Sondoss
- Hau Sion
- He Fa
- He Hanker
- He Henry
- He Karen
- He Lindong
- He Menglan
- He Peixiang
- He Yuna
- He Zhien
- Healy Liam
- Heath Emily
- Heger Theresa
- Hei Chan Yick
- Heijningen Franca van
- Heintze Maxime
- Hemmings Sam
- Heng Heng
- Heng Mary
- Henras Anthony
- Herbert Heydy
- Hernandez Ivan Martin
- Hernandez Laura Armero
- Herrmann Max
- Heux Stephanie
- Hewitt Amy
- Hiesinger Marlene
- Hill Kurt
- Hin Chan Lok
- Hin Wong Chung
- Hin Yu Man
- Ho Anthony
- Ho Ng Sze
- Ho Tim
- Hodson Sophie
- Hofer Sebastian
- Holman Olivor
- Holmedal Ingebjorg
- Hong Lai Tsz
- Hong Lee Chi
- Hong Yiquan
- Hong Yirui
- Horz Philip
- Hoskan Mehmet Ali
- Hosseini Reza
- Hou Ali
- Houmani Moustafa
- Hsiao Chia-Yi
- Hsieh Yi Da
- Hsu Chia-Wei
- Hsu Yi-Hsuan
- Hu Miao
- Hu Shi
- Hu Vivian
- Hu Wenyue
- Hu Xinyi
- Hu Yunyun
- Hu Zhaoqing
- Hu Zhiyuan
- Huang Fangliang
- Huang Jiaxi
- Huang Morris
- Huang Ray
- Huang William
- Huang Yansong
- Huang Yaohua
- Huang Yilin
- Huang Yinpin
- Huanying He
- HuaYue Zhang
- Huerta Ana Laura Torres
- Humphreys Christopher
- Hung Chia
- Husnatter Kai
- Huuki Liz
- Huynh Juilanne
- Hwang Michael
- Ibrahim Ahmed
- Ikagawa Yuichiro
- Ikhsan Muhammad
- Ikwuagwu Bon
- Imgold Markus
- Inanc Tugba
- Inckemann Rene
- Isaac Ashley
- Isaacs Farren
- Isogai Tatsuki
- Iwuogo Amanda
- Iyer Aditya
- Iyer Tvarita Shivakumar
- Izzati Nurul
- Jacq Annick
- Jain Rishabh
- Jain Shubham
- Jainarayanan Ashwin Kumar
- Jakutis Gabrielius
- Jaoui Samuel
- Japranata Valdi Ven
- Jaramillo Alfonso
- Jasiunas Simas
- Jasti Naveen
- Jay Leung Chung Yin
- Jayaraman Guhan
- Jayaraman Srimathi
- Jenakendran Jenaagan
- Jensen Joen Haahr
- Jesse Hayley
- Jha Aryaman
- Ji Peicheng
- Jiacheng Wu
- Jiahe Zhang
- Jiamiao Liu
- Jian Liu
- Jiang Nannan
- Jiang Zhenyu
- Jianzhao Yang
- Jiaqi Hu
- Jiaqi Xiao
- Jimenez Carlene
- Jin Kaifeng
- Jingjing Zhao
- Jinyu Zhu
- Jo Kyuhee
- Joe Lam Kai Ching
- Johnson Elizabeth
- Johnson Michael
- Jones Ari
- Jones Cara
- Jones Ethan
- Jones Megan
- Jones Melissa
- Jongkees Seino
- Jonsson Martin
- Jude Marcia Smiti
- Jung Younji
- Juskaite Ieva
- Justice Isaac
- Kabbara Ismat
- Kadimi Sricharan
- Kailash B.P.
- Kalinowski Jorn
- Kalinowski Jorn
- Kalson Pranshu
- Kamble Yash Laxman
- Kanata Eleni
- Kanaya Toshihiro
- Kang Han
- Kang Xu
- Kang Ziqi
- Kantas Gamze
- Kantor Nicole
- Kapsokefalou Maria
- Karpauskaite Laura
- Karpus Laurynas
- Karshenas Arman
- Karumanchi Pranathi
- Katherine Lai Man Wai
- Katopodi Xanthi Leda
- Kawasaki Yusuke
- Kayihan Ceyhun
- Keating Collin
- Kehan Tao
- Keidar Nitzan
- Keij Sander
- Kelly Ellis
- Kelly Julia
- Kennedy Fiona
- Kenneth Ng Tsz Chun
- Khaimani Jatin
- Khalid Alizah
- Khenwar Arundhati
- Kiga Daisuke
- Kim Anna
- Kim Christine
- Kim Dong Ju
- Kim Ellie
- Kim Gloria
- Kim Goeun
- Kim Grace
- Kim Sean
- Kin-ning Wong Carol
- King Stefanie
- Kittur M. Sagar
- Kiu Lee Hong
- Kiu Wong Hoi
- Kivisto Samu
- Klaas Liz
- Klopprogge Bjarne
- Ko LiangYu
- Kofoed Selma
- Kohabir Kavish
- Kolosova Anastasia
- Kong Cheng Chak
- Kong Linzhen
- Kortus Drew
- Koski Jessica
- Kostadima Eleni
- Kostopoulos Ioannis V.
- Kotzastratis Stylianos
- Kou Senhao
- Koutelidakis Antonios E.
- Kozhevnikov Adrian
- Krabacher Rachel
- Krainer Birgit
- Krauss Elisha
- Kristy Brandon
- Krokos Vasilios
- Kruger Dustin
- Krusemann Jan Lukas
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- Zhang Zixuan
- Zhao Nannan
- Zhao Peng
- Zhao Tianyan
- Zhao Wenxue
- Zhao Yihang
- Zhaoting Li
- Zhecheng Huang
- Zheng Daniel
- Zheng Jiyang
- Zhiwei Song
- Zhong Yanling
- Zhou Hanmi
- Zhou Jiajie
- Zhou Jianan
- Zhou Rui
- Zhou Shuyao
- Zhou Xuanhao
- Zhou Yanjun
- Zhou Yi
- Zhou Yinchi
- Zhou Yineng
- Zhou Yuezhang
- Zhou Yuxin
- Zhou Zhiyu
- Zhu Chushu
- Zhu Ke
- Zhu Xueqian
- Zi Lihan
- Zilinskaite Nemira
- Zimmermann Andreas
- Zimmermann Jennifer
- Zirong Zeng
- Ziwei Zhou
- Ziyi Zhao
- Zorrilla Francisco
- Zou Jiahua
- Zukauskaite Kristina
- Zulueta Patricia
- Zvirblyte Justina
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals <1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
- Allen Thaddeus
- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
- Ambrose Karen
- Ambrose Kerrie
- Amemiya Chris
- Amico-Keller Gina
- Amin Amita G.
- Anderson Mechele
- Anderson Scott
- Anderson Scott
- Andora Janice
- Andredesz Carol
- Andrew Robert
- Andrews Dan
- Andrews Daniel
- Andrews Neil
- Andrews Stephanie
- Andriese Tim
- Anthouard Véronique
- Antonarakis Stylianos E.
- Anyalebechi Vivian
- Aoki Norie
- Apostolou Sinoula
- Apweiler Eva
- Arachchi Harindra
- Arai Rie
- Arbery Hazel
- Arcaina Marlon
- Arcaina Terisita
- Archer Beth
- Arellano Andre
- Arellano-Jones Perry
- Armbruster Jeff
- Armstrong Jon
- Arredondo Dilrukshi P.
- Arredondo Heather Hope
- Artiguenave François
- Asakawa Shuichi
- Asakawa Teruyo
- Ash Gareth
- Ashcroft Kevin
- Ashurst Jennifer
- Ashwell Robert
- Ashworth Linda K.
- Aslanidis Cara
- Asomugha Chinwe O.
- Asuncion Lawreen
- Atkin Deborah
- Atkinson Andrea
- Atkinson Barry
- Attix Cristina
- Attwood John
- Aubin Keith
- Auger Katherine
- Austin Shannon Michelle
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- Benke J
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- Beugelsdijk Tony J.
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- Buckingham Judith M.
- Buckle Veronica
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- Cai Tianjing
- Cai Zhen
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- Zhang Xianglin
- Zhang Xiaoliang
- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
The First Post-Kepler Brightness Dips of KIC 8462852
- Author
- Alonso Roi
- Ammerman Alex
- Armstrong David
- Barkaoui K.
- Beatty Thomas G.
- Benkhaldoun Z.
- Benni Paul
- Bentley Rory O.
- Berdyugin Andrei
- Berdyugina Svetlana
- Bergeron Serge
- Bieryla Allyson
- Blain Michaela G.
- Blanco Alicia Capetillo
- Bodman Eva H. L.
- Boucher Anne
- Boyajian Tabetha. S.
- Bradley Mark
- Brincat Stephen M.
- Brink Thomas G.
- Briol John
- Brown David J. A.
- Budaj J.
- Burdanov A.
- Cale B.
- Carbo Miguel Aznar
- Clark Wendy J.
- Clayton Geoffrey C.
- Clem James L.
- Coker Phillip H.
- Cook Evan M.
- Copperwheat Chris M.
- Cseh B.
- Curtis J. L.
- Cutri R. M.
- Cynamon C. H.
- Daniels Alex J.
- Davenport James R. A.
- De Jaeger Thomas
- De Lorenzo Roberto
- Deeg Hans J.
- Desrosiers Jean-Bruno
- Dolan John
- Dowhos D. J.
- Dubois Franky
- Durkee R.
- Dvorak Shawn
- Easley Lynn
- Edwards N.
- Ellis Tyler G.
- Erdelyi Emery
- Ertel Steve
- Farfan Rafael. G.
- Farihi J.
- Filippenko Alexei V.
- Foxell Emma
- Gandolfi Davide
- Garcia Faustino
- Garcia R. Castillo
- Giddens F.
- Gillon M.
- Gonzalez M. J. Martinez
- Gonzalez-Carballo Juan-Luis
- Gonzalez-Fernandez C.
- Graham Keith A.
- Greene Kenton A.
- Gregorio J.
- Hallakoun Na'ama
- Hanyecz Otto
- Harp G. R.
- Henry Gregory W.
- Hernandez J. I. Gonzalez
- Herrero E.
- Hildbold Caleb F.
- Hinzel D.
- Holgado G.
- Ignacz Bernadett
- Ilyin Ilya
- Ivanov Valentin D.
- Jehin E.
- Jermak Helen E.
- Johnston Steve
- Kafka S.
- Kalup Csilla
- Kardasis Emmanuel
- Kaspi Shai
- Kennedy Grant M.
- Kessler Dennis
- Kiefer F.
- Kielty C. L.
- Kiiskinen H.
- Killestein T. L.
- King Ronald A.
- Kollar V.
- Konyves-Toth Reka
- Korhonen H.
- Kotnik C.
- Kriskovics Levente
- Krumm Nathan
- Krushinsky Vadim
- Kundra E.
- Lachapelle Francois-Rene
- LaCourse D.
- Lake P.
- Lam Kristine
- Lamb Gavin P.
- Lane Dave
- Lau Marie Wingyee
- Lewin Pablo
- Lintott Chris
- Lisse Carey
- Logie Ludwig
- Longeard Nicolas
- Ludington E. Whit
- Mainzer A.
- Malo Lison
- Maloney Chris
- Mann A.
- Mantero A.
- Marchant Jon
- Marengo Massimo
- Masiero Joseph R.
- Mauerhan Jon C.
- McCormac James
- McNeely Aaron
- Meng Huan Y. A.
- Miller Mike
- Molnar Lawrence A.
- Morales J. C.
- Morris Brett M.
- Muterspaugh Matthew W.
- Nespral David
- Nugent C. R.
- Nugent Katherine M.
- Nunez F. Pozo
- O'Keeffe Derek
- O'Meara John M.
- Odasso A.
- Oksanen A.
- Ordasi Andras
- Osborn Hugh
- Ott John J.
- Pal Andras
- Parks J. R.
- Perez Diego Rodriguez
- Petriew Vance
- Pickard R.
- Plavchan P.
- Plaza C. Westendorp
- Pollacco Don
- Pozuelos F. J.
- Ramos A. Asensio
- Rau Steve
- Redfield Seth
- Relles Howard
- Ribas Ignasi
- Richards Jon
- Saario Joonas L. O.
- Safron Emily J.
- Sallai J. Martin
- Sarneczky Krisztian
- Schaefer Bradley E.
- Schumer Clea F.
- Schwartzendruber Madison
- Siegel Michael H.
- Siemion Andrew P. V.
- Simmons Brooke D.
- Simon Joshua D.
- Simon-Diaz S.
- Sitko Michael L.
- Socas-Navarro Hector
- Sodor A.
- Starkey Donn
- Steele Iain A.
- Stone Geoff
- Strassmeier Klaus G.
- Street R. A.
- Sullivan Tricia
- Suomela J.
- Swift J. J.
- Szabo Gyula M.
- Szabo Robert
- Szakats Robert
- Szalai Tamas
- Tanner Angelle M.
- Toledo-Padron B.
- Tordai Tamas
- Triaud Amaury H. M. J.
- Turner Jake D.
- Ulowetz Joseph H.
- Urbanik Marian
- Vanaverbeke Siegfried
- Vanderburg Andrew
- Vida Krisztian
- Vietje Brad P.
- Villanueva M. Lopez
- Vinko Jozsef
- Von Braun K.
- Waagen Elizabeth O.
- Walsh Dan
- Watson Christopher A.
- Weir R. C.
- Wenzel Klaus
- Williamson Michael W.
- Wright Jason T.
- Wyatt M. C.
- Zheng WeiKang
- Zsidi Gabriella
- Publication venue
- 'American Astronomical Society'
- Publication date
- 01/01/2018
- Field of study
- …