41 research outputs found
Membrane and envelope virus proteins co-expressed as lysosome associated membrane protein (LAMP) fused antigens: a potential tool to develop DNA vaccines against flaviviruses
- Author
- ANWAR A ET AL
- ARRUDA LB ET AL
- ARRUDA LB ET AL
- BARRETT AD
- BARRETT AD
- CETRON MS ET AL
- CHIKHLIKAR P ET AL
- DONNELLY JJ ET AL
- DONNELLY JJ ET AL
- DRAKE JR ET AL
- Ernesto T.A. Marques Jr.
- ET AL
- Fábia S.P. Cruz
- Isabelle F.T. Viana
- KLEIJMEER MJ ET AL
- LEFEUVRE A ET AL
- LEWIS PJ
- LIPPINCOTT-SCHWARTZ J
- LIU MA
- LU Y ET AL
- MAECKER HT ET AL
- Mariana L. Palma
- Milton Maciel Jr.
- MONATH TP ET AL
- POLAND JD ET AL
- PUTNAK R ET AL
- Rafael Dhalia
- RAVIPRAKASH K ET AL
- RAVIPRAKASH K ET AL
- REINHARDT B ET AL
- ROBINSON HL
- ROCHA B
- SCHULTZ J ET AL
- Thomas August
- TURLEY SJ ET AL
- VASCONCELOS PF ET AL
- WU CJ ET AL
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Prenatal exposures and exposomics of asthma
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- Adamko DJ Sykes BD, Rowe BH
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- Publication venue
- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
- 01/01/2015
- Field of study
This review examines the causal investigation of preclinical development of childhood asthma using exposomic tools. We examine the current state of knowledge regarding early-life exposure to non-biogenic indoor air pollution and the developmental modulation of the immune system. We examine how metabolomics technologies could aid not only in the biomarker identification of a particular asthma phenotype, but also the mechanisms underlying the immunopathologic process. Within such a framework, we propose alternate components of exposomic investigation of asthma in which, the exposome represents a reiterative investigative process of targeted biomarker identification, validation through computational systems biology and physical sampling of environmental medi
Oncolytic virus efficiency inhibited growth of tumour cells with multiple drug resistant phenotype in vivo and in vitro
- Author
- A Chahroudi
- A Frentzen
- A Kanzaki
- A Saidi
- A Shanker
- A Worschech
- AV Sen’kova
- C Al Yaghchi
- C Lu
- C Thirukkumaran
- CH Contag
- CJ Breitbach
- D Byrd
- E Zonov
- EA Chiocca
- Elena P. Goncharova
- ET Valera
- F Yu
- GL Smith
- I Garcia-Tuñón
- IS Petrov
- Ivan S. Petrov
- J Bartkova
- J Li
- J Pol
- J Weissenberger
- JB Guillerme
- JE Teigler
- JG Marin
- JG Park
- JJ Marin
- JL Sherley
- Julia S. Ruzhenkova
- K Ehrig
- K Guse
- LC Wang
- LM Whilding
- LS Angelo
- M Kim
- M Trikha
- M Zeyaullah
- Marina A. Zenkova
- MH Verheije
- MS Ferguson
- MT Kuo
- N Mironova
- OG Donnelly
- PR Buijs
- PS Kim
- Q Yu
- R Pérez-Tomás
- R Xu
- RJ Prestwich
- RK Singh
- RS Coffin
- S Akiyama
- S Gholami
- S Greiner
- S Grivennikov
- S Nobili
- Sergey N. Shchelkunov
- SH Park
- SH Thorne
- SH Thorne
- SJ Russell
- SM Albelda
- T Tsuruo
- TS Miest
- V Felbert von
- VI Kaledin
- W Hou
- WM Chan
- World Health Organization
- X Yong
- Y Guo
- Y Shi
- Z Culig
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
The role of antioxidant therapy in the treatment of male infertility: an overview
- Author
- Abd-Allah AR
- Abd-Elmoaty MA
- Abel BJ
- Agarwal A
- Agarwal A
- Aitken RJ
- Aitken RJ
- Aitken RJ
- Aitken RJ
- Al-Gubory KH
- Andrea Lenzi
- Andrea Sansone
- Askari HA
- Baker HW
- Balercia G
- Balercia G
- Bellver J
- Cavallini G
- Chandra A
- Ciftci H
- Comhaire FH
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- Costa M
- Critser JK
- Desai N
- Donatella Paoli
- Donnelly ET
- Donnelly ET
- Francesco Lombardo
- Francesco Romanelli
- Gavella M
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- Geva E
- Greco E
- Griveau JF
- Griveau JF
- Hargreave TB
- Hendin BN
- Henkel R
- Hirsch A
- Hong CY
- Hughes CM
- Iwanier K
- Kao SH
- Keskes-Ammar L
- Kessopoulou E
- Kobayashi T
- Kodama H
- Kovalski NN
- Lenzi A
- Lenzi A
- Lenzi A
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- Lewin A
- Lewis SE
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- Loredana Gandini
- Makker K
- Mazzilli F
- McKinney KA
- Moilanen J
- Oeda T
- Okada H
- Omu AE
- Omu AE
- Paradiso Galatioto G
- Parinaud J
- Patel SR
- Rolf C
- Safarinejad MR
- Saleh RA
- Scott R
- Sharlip ID
- Sierens J
- Sigman M
- Suleiman SA
- Tarin JJ
- Tremellen K
- Twigg J
- Verma A
- Vezina D
- Vicari E
- Vicari E
- Wong WY
- Yumura Y
- Zini A
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
- Author
- Aahlin EK
- Aamer A
- Aaniana K
- Ababneh A
- Abaliksta T
- Abantanga F
- Abantanga F
- Abbas A
- Abbas M
- Abbasy J
- Abbo O
- Abbo O
- Abbott T
- Abbouch M
- Abd El Galeel A
- Abd El Hameed OS
- Abd El Hamid N
- Abd El Salam Y
- Abd El Slam M
- Abd El-Salam F
- Abd Elrasoul Y
- Abd-Elmawla M
- Abd-Elrasoul Y
- Abdallah E
- Abdallah E
- Abdel-Aty A
- Abdel-Hameed N
- Abdel-Kader SM
- Abdel-Wahab NYE
- Abdelaal A
- Abdelaty M
- Abdelazeam AR
- Abdelazim G
- Abdelaziz MA
- Abdelbadeai K
- Abdelfatah A
- AbdelFattah I
- Abdelgelil A
- Abdelghany S
- Abdelhady S
- Abdelhamed R
- Abdelhamid A
- Abdelhaq A
- Abdelkader M
- Abdelkader M
- Abdelkader O
- Abdelkareem A
- Abdelkhalek M
- Abdelmageed E
- Abdelmotaleb I
- Abdelraheim M
- Abdelraouf AM
- Abdelrouf DM
- Abdelshafy M
- Abdelshakour M
- Abdrabou AK
- Abdul-Latif S
- Abdulaziz H
- Abdulaziz M
- Abdulbagi O
- Abdulgawad M
- Abdulhakeem EM
- Abdullah AAN
- Abdullah MA
- Abdullah N
- Abdullah NAN
- Abdullah NAN
- Abdullahi L
- Abdurrazzaaq A
- Abebe NS
- Abebe NS
- Abem OE
- Aber A
- Abington E
- Abiola O
- Aboarab A
- Aboelella M
- Aboelmagd O
- Aboelsoud MR
- Aboraya M
- Aboraya M
- Abouelnasr A
- Aboul-Naga MS
- Abouzahra A
- Abouzaid A
- Abozaid M
- Abozeid K
- Abozyed MAF
- Abu Qumbos A
- Abu-toyour M
- Abubakr M
- Abudeeb H
- Abuowda Y
- Abuqwaider E
- Abusalem L
- Abuseif M
- Abushamleh S
- Acharya P
- Ackom E
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- Adenekan B
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- Arevalo Azmitia JR
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- Kobal BB
- Koh C
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- Koh PY
- Koh S
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- Kojo ATT
- Kojo ATT
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- Kolosov A
- Komolafe O
- Kondrotas P
- Kong C
- Kong SN
- Kong V
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- Konstantina K
- Kontos M
- Kordorwu HEK
- Korkolis D
- Kosai NR
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- Kose E
- Koskenvuo L
- Kostov E
- Kotb AHE-B
- Kotecha D
- Koto MZ
- Kotobi H
- Koumpa F
- Kouraklis G
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- Kyrou G
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- Labib P
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- Lam FY
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- Laugzemys E
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- Laurie K
- Lauzikas G
- Law JH
- Lawal A
- Lawal AO
- Lawal T
- Lawal TA
- Lawani I
- Lawther R
- Lazzari G
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- Lazzarini Cury AD
- Le VTH
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- Lecompte J-F
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- Leusink A
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- Lim G
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- Macfarlane A
- Machaca M
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- Maciejec L
- Madiba T
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- Madrid Barrientos LA
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- Mirza A
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- Mohamed F
- Mohamed I
- Mohamed M
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- Mohamed MM
- Mohamed O
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- Mohammad A
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- Montrimaite M
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- Samaraweera DI
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- Senanayake KJ
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- Snyder E
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- Publication venue
- Publication date
- 15/10/2018
- Field of study
Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients included from 76 countries, 4843 underwent emergency laparotomy. After adjusting for patient and disease factors, checklist use before emergency laparotomy was more common in countries with a high Human Development Index (HDI) (2455 of 2741, 89.6 per cent) compared with that in countries with a middle (753 of 1242, 60.6 per cent; odds ratio (OR) 0.17, 95 per cent c.i. 0.14 to 0.21, P <0001) or low (363 of 860, 422 per cent; OR 008, 007 to 010, P <0.001) HDI. Checklist use was less common in elective surgery than for emergency laparotomy in high-HDI countries (risk difference -94 (95 per cent c.i. -11.9 to -6.9) per cent; P <0001), but the relationship was reversed in low-HDI countries (+121 (+7.0 to +173) per cent; P <0001). In multivariable models, checklist use was associated with a lower 30-day perioperative mortality (OR 0.60, 0.50 to 073; P <0.001). The greatest absolute benefit was seen for emergency surgery in low- and middle-HDI countries. Conclusion Checklist use in emergency laparotomy was associated with a significantly lower perioperative mortality rate. Checklist use in low-HDI countries was half that in high-HDI countries.Peer reviewe
Global variation in anastomosis and end colostomy formation following left-sided colorectal resection
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- Callan R
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- Camilleri-Brennan J
- Camilleri-Brennan Jf
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- Canto Md
- Capito C
- Capleton P
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- Careta Mc
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- Carmona Jm
- Carneros Vj
- Carpio J
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- Carreira Ja
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- Castillo Vdp
- Castro Mr
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- Caydiid H
- Cecilia T
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- Cengiz Tb
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- Cevik M
- Chabok A
- Chachulski W
- Chai Ca
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- Chambers A
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- Chan Tk
- Chan Xw
- Chan Z
- Chandrakumar C
- Chang K
- Chang Ky
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- Chapman Sj
- Charles A
- Cheah Aez
- Chen Cy
- Chen Jhc
- Chen Ky
- Chen Tl
- Chenn R
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- Chetta N
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- Chew Ls
- Chhabra S
- Chibuye C
- Chidambaram S
- Chiesa D
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- Chiu S
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- Chiu Smy
- Choi J
- Choi P
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- Chong Cs
- Chong Hy
- Chong Hy
- Choudhry A
- Chow Cyn
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- Chowdhury D
- Chu K
- Chun A
- Chun T
- Chung Kj
- Chung S
- Ciccioli E
- Cirocchi R
- Ciubotaru C
- Claire R
- Clarissa A
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- Clegg-Lampety Jn
- Clegg-Lamptey Jn
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- Colombani Jf
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- Dé
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- Da Silva LA
- Dabboor M
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- Dan I
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- Daniyan M
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- Dao W
- Daqeeq A
- Dar M
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- Darweesh M
- Darwish Ak
- Das A
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- Datta U
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- De Castro Segundo LCB
- De Franciscis S
- De Freitas AVC
- De La Medina AR
- de Leó
- De Leon MZP
- De Leon MZP
- de Lima CVB
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- Debrah S
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- Deichsel F
- Del Basso C
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- Delgado Jm
- Delgado Msftl
- Dell A
- Dempster E
- Denewar A
- Depalma N
- Deputy M
- Der Y
- Dervenis C
- Despotidis V
- Desta S
- Deutschmann P
- Devadasar Gh
- Dharamshi Ha
- Dhillon D
- Di Franco F
- Di Martino N
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- Di Saverio S
- Diab A
- Diaconescu B
- Diaconescu Ib
- Dias S
- Diaz-Jover P
- Diaz-Zorrilla C
- Dick L
- Dickfos M
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- Din F
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- Dindyal S
- Dissanayake T
- Djivoh F
- Domini E
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- Donnelly P
- Donoghue D
- Dorani Rmnr
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- Dossou F
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- Driscoll A
- Drungilas M
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- Dueñ
- Duffy L
- Duhoranenayo D
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- Dulskas A
- Durand Sya
- Dwydar A
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- Ebidy M
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- Ebrahim Os
- Eduard P
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- El Deen KN
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- El Jamassi A
- El Kashash A
- El Kholy A
- El Magd AA
- El Mesery S
- El Salam YA
- El Sayed GS
- El Sayed IM
- El Shoura Y
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- El-Dien Ks
- El-Din Ra
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- El-Gizawy E
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- El-Ma&apos
- El-Rabaa S
- El-Sagheer N
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- El-Sawy A
- El-Sehily A
- El-Shahat Ns
- El-Sheemy H
- El-Taher E
- Elabdin Hz
- Elashmawy M
- Elashry R
- Elazab A
- Elazayem Aa
- Elazoul M
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- Elbatahgy A
- Elbe P
- Elbermawy M
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- Eldeeb Az
- Eldeen Ea
- Eldin Mab
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- Elebute O
- Elena G
- Elfarargy A
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- Elfeki H
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- Elgendy Fi
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- Elkholy A
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- Elkolaly Ss
- Elkorashy Am
- Ellison Q
- Elmashala A
- Elmasry M
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- Elmihy S
- Elnagar A
- Elnajjar Ma
- Elnemr Ae
- Elrasoul Ya
- Elrazek Aa
- Elsabbagh N
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- Elsawahly Dme
- Elsawy A
- Elsayed M
- Elsayed M
- Elsayed N
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- Elsayed Zm
- Elsebaaye Ao
- Elsehimy M
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- Elshafay Ae
- Elshami M
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- Elsherbiney S
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- Elsherif Fa
- Elshobary M
- Elsiddig M
- Elsobky S
- Elsorogy Deaa
- Elwaey A
- Elwakil H
- Elwan A
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- Elwy E
- Elzahed N
- Elzayat I
- Elzayat M
- Elzayyat I
- Elzowawi F
- Emadeldin D
- Emadeldin H
- Emara E
- Emile S
- Eng C
- English W
- Esam A
- Escobar Eg.
- Espin-Basany E
- Espinoza F
- Espinoza Kt
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- Essam A
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- Essoun S
- Esteban E
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- Estupinian S
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- Etchill E
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- Etman M
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- Evans E
- Eysa A
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- Ezzat T
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- Fahiem A
- Fahim M
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- Fairfield C
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- Farag S
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- Faraz A
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- Farhan-Alanie Mmh
- Farhangmehr N
- Farinella E
- Farmakis K
- Farooq T
- Farouk Sam
- Farquharson A
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- Farrugia A
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- Fathy Am
- Fattah Aa
- Fatuga A
- Faturoti O
- Faturoti O
- Faure A
- Fautz T
- Favero A
- Fawzy A
- Feidantsis T
- Felipe Co
- Fergany A
- Fergusson Sj
- Fergusson Sj
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- Fermani C
- Fermani Cg
- Ferná
- Fernandes C
- Fernandez-Bueno F
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- Ferousis C
- Ferreira Sak
- Ferrero E
- Fievet L
- Filatau A
- Findlay-Cooper K
- Firdouse M
- Firdouse M
- Firdouse M
- Firwana A
- Fitsum A
- Fitzgerald Je
- Florez Ljg
- Foco M
- Fok Cyj
- Fontana T
- Foo Cc
- Forlin L
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- Fouad A
- Fouad D
- Fouad D
- Fourcade L
- Fowler Aj
- Fozard T
- Fozard T
- Frade F
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- Francois P
- Francois-Coridon H
- Francone E
- Freitas Av
- Frey D
- Frisk B
- Fuentes-Rivera L
- Fujii F
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- Gü
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- Gaafar S
- Gaarder T
- Gad A
- Gad Mo
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- Gadhvi V
- Gado A
- Gaiž
- Gaignard E
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- Gala T
- Gala T
- Galiqi G
- Galleano R
- Gallo G
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- Galvez Cp
- Gamal D
- Gamal E
- Gamal H
- Gamal S
- Gamaly E
- Gamil D
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- Gan Yy
- Gani Ma
- Garaycochea O
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- Garcia-Marin Ja
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- Garland A
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- Gemeah M
- Gemenetzis G
- Gemenetzis G
- George R
- Germanos S
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- Gerosa A
- Gerosa A
- Geuoshy A
- Ghaben A
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- Ghanem E
- Ghanem S
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- Ghannam M
- Gharib A
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- Ghazy Aa
- Gheith A
- Ghetia M
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- Ghoneim O
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- Giglio Mc
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- Giuriato Tf
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- Goldin E
- Golding D
- Gomaa A
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- Griffiths E
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- Grizhja B
- Grobler Dc
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- Gudal A
- Gudal A
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- Guevara R
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- Gui D
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- Gulielmi A
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- Gustafsson U
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- Haddad N
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- Halicioglu I
- Hall E
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- Hamarshi A
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- Hamdan A
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- Hassaan A
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- Ibraheem Aa
- Ibraheem Hi
- Ibrahem Aa
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- Ibrahim A
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- Ibrahim Am
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- Ibrahim I
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- Ibrahim M
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- Imoro O
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- Landolfo G
- Lap G
- Lapitan Mc
- Lapitan Mc
- Larsen Jw
- Lasek A
- Lasheen A
- Lasheen Kt
- Latif A
- Laufer Lav
- Laugzemys E
- Laugzemys E
- Laurie K
- Lauzikas G
- Law Jh
- Lawal A
- Lawal Ao
- Lawal T
- Lawal Ta
- Lawani I
- Lawther R
- Lazzari G
- Lazzari V
- Leal A
- Leal M
- Lecompte Jf
- Lee C
- Lee Ex
- Lee F
- Lee K
- Lee Kc
- Lee Ky
- Lee Tsb
- Lemaire Sb
- Leone N
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- Leppä
- Leppä
- Leroux J
- Leung Kw
- Leung Mf
- Leusink A
- Lewis J
- Li Ws
- Licari L
- Lieske B
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- Liew I
- Liew I
- Lilford R
- Lilford R
- Lilford Rj
- Lim G
- Lim H
- Lim J
- Lim Pj
- Lim Sj
- Lim Sj
- Lim Sy
- Limache S
- Limaye N
- Limoges B
- Lintin L
- Lipnickas V
- Litvin A
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- Livesey A
- Livingston M
- Ljuhar D
- Lo Conte A
- Loaloa Mr
- Lockey J
- Lohse Has
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- Loizides S
- Lokman Maa
- Longstaff L
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- Lopez Lip
- Lopez M
- Lopez M
- Lopez-Arevalo C
- Lorenzon L
- Lossius Wj
- Loughran D
- Low X
- Luc Ar
- Luck J
- Luck J
- Luck J
- Luglio G
- Lund J
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- Lundgren Po
- Luque Gb
- Luque L
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- Lytras D
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- Má
- Mé
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- Mañ
- Ma J
- Mabitsela Me
- Mabrouk M
- Macchiavello R
- Macchitella Y
- Macchitella Y
- Macdermid E
- Macdonald A
- Macdonald E
- Macdonald L
- Maceviciute K
- Macfarlane A
- Machaca M
- Maciejec L
- Madiba T
- Madkor Mh
- Maffioli A
- Maffioli A
- Magdy A
- Magdy B
- Magdy E
- Magdy H
- Magdy M
- Magdy S
- Magee C
- Maghrabi A
- Maghrabi Aa
- Magri D
- Mahamood Ab
- Mahanty S
- Maharaj G
- Mahdi A
- Mahdi S
- Mahdi S
- Maher Me
- Mahmoud B
- Mahmoud H
- Mahmoud M
- Mahmoud Ma
- Mahmoud Mi
- Mahmoud S
- Mahmoud Sme
- Mahmud K
- Maillot B
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- Maison K
- Maistry N
- Majauskyté
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- Majid Ahha
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- Makama J
- Makinde M
- Makupe A
- Malavenda M
- Malik K
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- Mamdouh E
- Mamdouh R
- Manatakis Dk
- Manfreda S
- Mangan C
- Mangan C
- Mangiapane M
- Manipal Ce
- Maniscalco A
- Mann T
- Mannu Gs
- Manriquez-Reyes M
- Mansor Ey
- Mansour B
- Mansour S
- Mansuri A
- Mao P
- Mapasse D
- Maple N
- Maraie N
- Marey A
- Marey As
- Margaritis M
- Mariani A
- Marinkovic B
- Marinos C
- Marks E
- Marples L
- Marret Jb
- Marshall Dc
- Martian Bv
- Martin A
- Mas R
- Mason C
- Mata Lps
- Matheu A
- Mathew Sw
- Matos-Puig R
- Matta Jjh
- Mattar O
- Matter Sm
- Mauro L
- Mayasari M
- Mazelyte R
- Mazrimas P
- Mazzella A
- Mcaleer E
- Mcaleer S
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- Mccarthy M
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- Mcdonald R
- McGarvie S
- Mcguigan A
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- McMorran D
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- Mehrez S
- Mejia Agv
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- Mendizabal Caa
- Mendoza I
- Menegussi J
- Mensah E
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- Mentula P
- Meqbil J
- Mericliler M
- Merlini D
- Merlini D
- Merlo Ms
- Mesbah N
- Meshref A
- Metwally Mm
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- Miguel Gps
- Mihaljevic Al
- Mihanovic J
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- Mijuskovic B
- Mikalauskas S
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- Mikuckyte D
- Mikwar Z
- Milligan W
- Milligan W
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- Minguez G
- Minocha A
- Minocha A
- Miranda C
- Mircea H
- Mirghani D
- Mironescu A
- Mironescu A
- Mironescu As
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- Mirza A
- Mirza S
- Mistry A
- Mitrasinovic S
- Mitroudi M
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- Mizzi C
- Mizzi S
- Mlotshwa M
- Moaty M
- Mochet S
- Modolo Mm
- Modolo Mm
- Modolo Mm
- Moe Tt
- Mogan Yp
- Moghazy Me
- Mohamed A
- Mohamed A
- Mohamed Am
- Mohamed Ar
- Mohamed B
- Mohamed F
- Mohamed I
- Mohamed M
- Mohamed Ma
- Mohamed Maeh
- Mohamed Mm
- Mohamed O
- Mohamed Sr
- Mohameden A
- Mohammad A
- Mohammad A
- Mohammed A
- Mohammed A
- Mohammed Ae
- Mohammed Ar
- Mohammed H
- Mohammed Mm
- Mohammed Mmh
- Mohammed S
- Mohan H
- Mohan M
- Mohan M
- Mok Yt
- Mokhtar A
- Molina G
- Mollo Mc
- Monaghan E
- Monaghan E
- Monrad-Hansen Pw
- Montejo Msg
- Monteleone M
- Monteleone M
- Montes I
- Montes I
- Montrimaite M
- Montrimaite M
- Moodley Y
- Moore R
- Moore R
- Mora Jjv
- Morais Pab
- Morales C
- Moran Aer
- Morandi E
- Moreira G
- Moreno Sc
- Morgan C
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- Morshedy Em
- Morsi A
- Morsi M
- Morton D
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- Morton R
- Mosad A
- Mosalum O
- Mostafa Ha
- Mostafa M
- Mostafa M
- Mousa M
- Moussa O
- Moustafa A
- Mouttalib S
- Mowafy B
- Mphatsoe Am
- Mshelbwala P
- Msiska N
- Msosa V
- Msosa V
- Muddebihal U
- Mukin Adf
- Muktar U
- Mukuzunga C
- Muller C
- Muller C
- Munera A
- Munhoz Mm
- Munipalle Pc
- Muntean L
- Muntean Li
- Muralha N
- Murphy J
- Murray A
- Murutoglu B
- Musa Aek
- Musleh A
- Musowoya J
- Mussad A
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- Mustafa M
- Mustafa Ma
- Musyoka Ck
- Mutabazi Az
- Mutabazi Az
- Mutlu D
- Mutlu V
- Muzio E
- Myers J
- Mykoniatis I
- Næ
- Nabawi A
- Nada F
- Nadeem N
- Nadkarni S
- Nagy Gs
- Nahar Sn
- Nair H
- Nanthakumaran S
- Napolitano L
- Napolitano L
- Naqvi Sa
- Naqvi T
- Naranjo Aristizã
- Narayanan R
- Narayanan R
- Narvestad Jk
- Nashaat A
- Nashat M
- Nasher O
- Nashidengo P
- Nasir A
- Nasir Aa
- Nasr A
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- Nasr M
- Nassif D
- Nastri G
- Natalie H
- Nataraja R
- Natili A
- Navarro A
- Nawara C
- Nawawi A
- Nawawi A
- Nayel Ar
- Nazir M
- Ndajiwo A
- Ndajiwo A
- Ndegwa W
- Ndlovu Sr
- Ndwambi P
- Ne&apos
- Negida A
- Negoi I
- Nel D
- Nemeth K
- Neo Yn
- Neo Yt
- Neophytou C
- Nepogodiev D
- Nepogodiev D
- Nepogodiev D
- Nepogodiev D
- Nesaratnam A
- Nessa A
- Nestorovic M
- Nevieraite V
- Newton T
- Ng S
- Ng Yk
- Ng Zh
- Ngayu N
- Ngwa Te
- Niazi Ak
- Nicholson L
- Nighat B
- Nigo S
- Nikberg M
- Nikoloudis N
- Nikoloudis N
- Niragire A
- Niranjan N
- Nirumal Mk
- Niska K
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- Niyirera E
- Njokanma I
- Nnajiuba H
- Nocito A
- Nocito A
- Nofal E
- Noor F
- Normile C
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- North As
- Notarnicola M
- Notarnicola M
- Nouh T
- Nouh T
- Noukpozounkou B
- Novak A
- Nowers J
- Nsengimana Vjp
- Nsengiyumva C
- Ntirenganya F
- Nur&apos
- Nurqistan Hd
- Nwabuoku E
- Nwinee V
- Nwokoro C
- Nyberg J
- Nymo L
- O&apos
- O&apos
- O&apos
- O&apos
- O&apos
- O&apos
- Obute Rd
- Occhionorelli S
- Odeyemi B
- Odeyemi B
- Odutola O
- Ogunsua O
- Ogunyemi A
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- Oh J
- Ohene-Yeboah M
- Ojeda Rrb
- Okenabirhie O
- Olajide To
- Olaolorun A
- Olivier J
- Olori S
- Olori S
- Oludara M
- Oludara M
- Olugbemi M
- Omar Aa
- Omar Me
- Omar Mfw
- Omara S
- Omer Oa
- Onimowo J
- Onuoha C
- Oosterkamp A
- Opoku-Agyeman R
- Oram S
- Orbegozo Pat
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- Ortega I
- Ortega I
- Ortega-Vazquez I
- Ortiz N
- Orton P
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- Osei-Nketiah S
- Oshati O
- Oshodi O
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- Osinowo A
- Osman M
- Osman N
- Osman O
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- Oswald D
- Otero-Dí
- Othman M
- Ots R
- Otten K
- Oumer R
- Owen C
- Owusu F
- Owusu F
- Ozben V
- Ozkan Bb
- Ozkan Bb
- Ozkan Bb
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- Paž
- Pabla G
- Pacheco Rda
- Padmore G
- Pagano G
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- Pagnozzi J
- Pahlsson Hi
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- Palayan K
- Palkhi Eya
- Palliyil M
- Palliyil Mm
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- Palma Af
- Paludi Ma
- Paludi Ma
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- Panez Wr
- Panieri E
- Panteli C
- Papageorgiou D
- Papailia A
- Papandrea M
- Papaskarlatos Ia
- Pape J
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- Parakh J
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- Parasyris S
- Pardo G
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- Parmentier B
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- Parreno-Sacdalan Md
- Parseliunas A
- Parthiban S
- Pascale G
- Pascale Mm
- Pasini M
- Pasquali S
- Pastora J
- Pata D
- Pata D
- Pata F
- Pata F
- Pata F
- Pata F
- Pata F
- Pata F
- Pata G
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- Patel P
- Patel P
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- Patel V
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- Patoulias I
- Paul M
- Paul S
- Paulouski D
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- Pektaş
- Pellino G
- Peltrini R
- Pereira B
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- Perera J
- Periasammy D
- Perino M
- Peros G
- Perrotta G
- Pesenti G
- Petrikenas S
- Peycelon M
- Peycelon M
- Pezas T
- Pezas T
- Pezelj N
- Phillips N
- Picardo A
- Picciariello A
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- Pineñ
- Pinkney T
- Pinkney Td
- Pinnagoda K
- Pino W
- Pitt Sk
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- Pluke K
- Poš
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- Popoola A
- Porter J
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- Poskus T
- Poskus T
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- Powell A
- Pozo Dar
- Prabhudesai A
- Pranevicius R
- Prasad Ss
- Preckailaite E
- Primavesi F
- Prins M
- Proctor Vk
- Pronin S
- Prudhomme T
- Psaila J
- Psarianos K
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- Pugliesi Tb
- Pujol-Cano N
- Puma Cmh
- Punja V
- Purwaningsih Na
- Puttick M
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- Qawasmi I
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- Quayle J
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- Quezada Jhj
- Qumbos Aa
- Qureshi Au
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- Rahantasoa Fcfp
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- Rasoaherinomenjanahary F
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- Raza A
- Raza I
- Raza I
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- Razmdjou S
- Razuri C
- Razzaque J
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- Recinos G
- Recinos G
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- Redgrave N
- Redota Map
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- Renaux-Petel M
- Restrepo Im
- Restrepo J
- Reunis E
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- Roche Mo
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- Rodriguez X
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- Runigamugabo E
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- Saad Ha
- Saad M
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- Saar S
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- Sabour Fa
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- Sahel S
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- Salama M
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- Sallinen V
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- Salma M
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- Salma U
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- Sam Zh
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- Samaniego Cs
- Samaraweera Di
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- Sammarco G
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- Sanz S
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- Sarafilovic H
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- Saravia F
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- Schiavone R
- Schivo D
- Schmid R
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- Schultz Jk
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- Semeda N
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- Senanayake Kj
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- Senanayake W
- Septiem Jg
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- Setiawan J
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- Shah A
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- Shahbaz Ar
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- Shamsedine Aw
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- Shawqi M
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- Shehata S
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- Siguantay M
- Sigurdadottir J
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- Sila Gcm
- Sila Gm
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- Silvestri V
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- Sivaganesh S
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- Smedley A
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- Snyder E
- Sobnach S
- Sodde P
- Soeselo Da
- Sokratous A
- Solaini L
- Soldevila-Verdeguer C
- Soley R
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- Sollazzo V
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- Souaibou Yi
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- Srinivasan R
- Sriram A
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- Suarez A
- Suarez Aab
- Subocius A
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- Summerour V
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- Sundstrom Sm
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- Sykes M
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- Tade A
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- Tahboub H
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- Tan Jk
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- Tan Yk
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- Tanase A
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- Tang L
- Tani Si
- Tansoker I
- Tarek A
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- Tarek D
- Targa S
- Tariq S
- Tata Md
- Tatagiba Ls
- Tawfik Ba
- Tawfik G
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- Tedeschi U
- Tedjaatmadja C
- Telfah Mm
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- Temoche E
- Tennakoon A
- Teo Sy
- Ter Ez
- Tessera G
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- Tew Yy
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- Tewari S
- Th&apos
- Thabet W
- Thalgaspitiya Spb
- Tham Jc
- Thanusan V
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- Theodosopoulos T
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- Thorell A
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- Thurairaja R
- Ticona Wa
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- 'Wiley'
- Publication date
- 27/11/2018
- Field of study
Background
End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection.
Methods
This study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies (2014, 2016), including consecutive adult patients undergoing elective or emergency left-sided colorectal resection within discrete 2-week windows. Countries were grouped into high-, middle- and low-income tertiles according to the United Nations Human Development Index (HDI). Factors associated with colostomy formation versus primary anastomosis were explored using a multilevel, multivariable logistic regression model.
Results
In total, 1635 patients from 242 hospitals in 57 countries undergoing left-sided colorectal resection were included: 113 (6·9 per cent) from low-HDI, 254 (15·5 per cent) from middle-HDI and 1268 (77·6 per cent) from high-HDI countries. There was a higher proportion of patients with perforated disease (57·5, 40·9 and 35·4 per cent; P < 0·001) and subsequent use of end colostomy (52·2, 24·8 and 18·9 per cent; P < 0·001) in low- compared with middle- and high-HDI settings. The association with colostomy use in low-HDI settings persisted (odds ratio (OR) 3·20, 95 per cent c.i. 1·35 to 7·57; P = 0·008) after risk adjustment for malignant disease (OR 2·34, 1·65 to 3·32; P < 0·001), emergency surgery (OR 4·08, 2·73 to 6·10; P < 0·001), time to operation at least 48 h (OR 1·99, 1·28 to 3·09; P = 0·002) and disease perforation (OR 4·00, 2·81 to 5·69; P < 0·001).
Conclusion
Global differences existed in the proportion of patients receiving end stomas after left-sided colorectal resection based on income, which went beyond case mix alone
From the first to the latest vaccines in Veterinary Medicine
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