284 research outputs found

    Probing key informants’ views of health equity within the World Health Organization’s Urban HEART initiative

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    To date, no studies have assessed how those involved in the World Health Organization’s (WHO) work understand the concept of health equity. To fill the gap, this research poses the question, “how do Urban Health Equity Assessment and Response Tool (Urban HEART) key informants understand the concept of health equity?”, with Urban HEART being selected given the focus on health equity. To answer this question, this study undertakes synchronous electronic interviews with key informants to assess how they understand health equity within the context of Urban HEART. Key findings demonstrate that: (i) equity is seen as a core value and inequities were understood to be avoidable, systematic, unnecessary, and unfair; (ii) there was a questionable acceptance of need to act, given that political sensitivity arose around acknowledging inequities as “unnecessary”; (iii) despite this broader understanding of the key aspects of health inequity, the concept of health equity was seen as vague; (iv) the recognized vagueness inherent in the concept of health equity may be due to various factors including country differences; (v) how the terms “health inequity” and “health inequality” were used varied drastically; and (vi) when speaking about equity, a wide range of aspects emerged. Moving forward, it would be important to establish a shared understanding across key terms and seek clarification, prior to any global health initiatives, whether explicitly focused on health equity or not.publishedVersio

    Single- and multi-peak solitons in two-component models of metamaterials and photonic crystals

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    We report results of the study of solitons in a system of two nonlinear-Schrodinger (NLS) equations coupled by the XPM interaction, which models the co-propagation of two waves in metamaterials(MMs). The same model applies to photonic crystals (PCs), as well as to ordinary optical fibers, close to the zero-dispersion point. A peculiarity of the system is a small positive or negative value of the relative group-velocity dispersion (GVD) coefficient in one equation, assuming that the dispersion is anomalous in the other. In contrast to earlier studied systems of nonlinearly coupled NLS equations with equal GVD coefficients, which generate only simple single-peak solitons, the present model gives rise to families of solitons with complex shapes, which feature extended oscillatory tails and/or a double-peak structure at the center. Regions of existence are identified for single- and double-peak bimodal solitons, demonstrating a broad bistability in the system. Behind the existence border, they degenerate into single-component solutions. Direct simulations demonstrate stability of the solitons in the entire existence regions. Effects of the group-velocity mismatch (GVM) and optical loss are considered too. It is demonstrated that the solitons can be stabilized against the GVM by means of the respective "management" scheme. Under the action of the loss, complex shapes of the solitons degenerate into simple ones, but periodic compensation of the loss supports the complexity.Comment: Optics Communications, in press (Special Issue on Nonlinear Metamaterials

    Photocatalytic activity of nitrogen-doped TiO2-based nanowires: a photo-assisted Kelvin probe force microscopy study

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    The emerging industrial business partnerships, which feature cross-functional and cross-company development efforts, raise the barrier for the establishment of effective knowledge sharing practices in the larger organization. This chapter aims to highlight the role of knowledge as a key enabler for effective engineering activities in the light of such emerging enterprise collaboration models. Knowledge Enabled Engineering (KEE) is presented as an approach to enhance the extended organization’s capability to establish effective collaboration among its parts, in spite of different organizational structures, technologies or processes. KEE is analysed in its constituent parts, highlighting areas, methods and tools that are particularly interesting for leveraging companies’ knowledge sharing capabilities

    Subwavelength anti-diffracting beams propagating over more than 1,000 Rayleigh lengths

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    Propagating light beams with widths down to and below the optical wavelength require bulky large-aperture lenses and remain focused only for micrometric distances. Here, we report the observation of light beams that violate this localization/depth- of-focus law by shrinking as they propagate, allowing resolution to be maintained and increased over macroscopic propagation lengths. In nanodisordered ferroelectrics we observe a non-paraxial propagation of a sub-micrometre-sized beam for over 1,000 diffraction lengths, the narrowest visible beam reported to date. This unprecedented effect is caused by the nonlinear response of a dipolar glass, which transforms the leading opticalwave equation into a Klein-Gordon-type equation that describes a massive particle field. Our findings open the way to high-resolution optics over large depths of focus, and a route to merging bulk optics into nanodevices

    The Astronomical Orientation of Ancient Greek Temples

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    Despite its appearing to be a simple question to answer, there has been no consensus as to whether or not the alignments of ancient Greek temples reflect astronomical intentions. Here I present the results of a survey of archaic and classical Greek temples in Sicily and compare them with temples in Greece. Using a binomial test I show strong evidence that there is a preference for solar orientations. I then speculate that differences in alignment patterns between Sicily and Greece reflect differing pressures in the expression of ethnic identity

    Which patient will feel down, which will be happy? The need to study the genetic disposition of emotional states

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    Purpose In quality-of-life (QL) research, the genetic susceptibility of negative and positive emotions is frequently ignored, taken for granted, or treated as noise. The objectives are to describe: (1) the major findings of studies addressing the heritable and environmental causes of variation in negative and positive emotional states and (2) the major biological pathways of and genetic variants involved in these emotional states

    The effects of compaction delay and environmental temperature on the Mechanical and Hydraulic properties of lime-stabilized extremely high plastic clays

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    yesA comprehensive experimental programme was performed with the focus on assessing the effects of compaction delay and ambient temperature on the physical, mechanical and hydraulic properties of lime treated expansive clays. Specimens were mellowed for a period of 0, 3, 6, 12, 24 and 48 h at two different temperatures of 20°C and 40°C prior to being compacted, tested and/or cured for up to 28 days for evaluating the impacts on long-term strength development. All specimens were prepared with the same dry unit weight of 12.16 kN/m3 and moisture content of 40% except for tests aimed at determining dry unit weight as a function of mellowing period. The results revealed that as the mellowing duration increased the dry unit weight declined remarkably at both temperature within the first 12 h. In addition, higher reduction rate was observed when specimens were mel-lowed at a temperature of 40°C. A 97% reduction in swelling pressure was obtained when the specimens were compacted upon mixing (zero hour mellowing period) and left to cure for 24 h prior to testing. Permeability coefficient of lime treated expansive clays was increased by up to 40 times when compaction was delayed for 24 h or when specimens were mellowed at 40°C. Specimens mellowed at a temperature of 40°C showed rela-tively stable values of permeability coefficient over the measurement period which could be attributable to accelerated pozzolanic reaction. The Unconfined Compressive Strength tests revealed that strength of lime treated expansive clays is significantly affected by compaction delay. An increase of 234% and 282% in the Unconfined Compressive Strength was achieved after 24 h of mixing with no compaction delay at 20°C and 40°C respectively. Gradual long-term gain in strength was observable within the 28 days post mixing but the rate of strength gain becomes slower and independent of temperature after the first 24 h of mixing. The results sug-gested that the four key reaction mechanisms occur concurrently with the first 12–24 h after lime addition recognized as being the most crucial period of time. Damaging the cementitious compounds by delayed com-paction is harmful to strength and restraining of swelling potential of lime treated expansive clays

    A high fat diet increases mitochondrial fatty acid oxidation and uncoupling to decrease efficiency in rat heart

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    Elevated levels of cardiac mitochondrial uncoupling protein 3 (UCP3) and decreased cardiac efficiency (hydraulic power/oxygen consumption) with abnormal cardiac function occur in obese, diabetic mice. To determine whether cardiac mitochondrial uncoupling occurs in non-genetic obesity, we fed rats a high fat diet (55% kcal from fat) or standard laboratory chow (7% kcal from fat) for 3 weeks, after which we measured cardiac function in vivo using cine MRI, efficiency in isolated working hearts and respiration rates and ADP/O ratios in isolated interfibrillar mitochondria; also, measured were medium chain acyl-CoA dehydrogenase (MCAD) and citrate synthase activities plus uncoupling protein 3 (UCP3), mitochondrial thioesterase 1 (MTE-1), adenine nucleotide translocase (ANT) and ATP synthase protein levels. We found that in vivo cardiac function was the same for all rats, yet oxygen consumption was 19% higher in high fat-fed rat hearts, therefore, efficiency was 21% lower than in controls. We found that mitochondrial fatty acid oxidation rates were 25% higher, and MCAD activity was 23% higher, in hearts from rats fed the high fat diet when compared with controls. Mitochondria from high fat-fed rat hearts had lower ADP/O ratios than controls, indicating increased respiratory uncoupling, which was ameliorated by GDP, a UCP3 inhibitor. Mitochondrial UCP3 and MTE-1 levels were both increased by 20% in high fat-fed rat hearts when compared with controls, with no significant change in ATP synthase or ANT levels, or citrate synthase activity. We conclude that increased cardiac oxygen utilisation, and thereby decreased cardiac efficiency, occurs in non-genetic obesity, which is associated with increased mitochondrial uncoupling due to elevated UCP3 and MTE-1 levels

    Advancing an energy justice perspective of fuel poverty: Household vulnerability and domestic retrofit policy in the United Kingdom

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    The concept of energy justice has brought philosophies of ethics and principles of social justice to bear on a range of contemporary energy issues. More inter-disciplinary and applied endeavours are now needed to take this field forward. One such application is to the issue of fuel poverty and the challenge of retrofitting inefficient housing stock. An energy justice perspective sees fuel poverty as a fundamentally socio-political injustice, not just one of uneven distribution. Starting from this premise, we highlight the multiple injustices faced by two groups who are regarded by policymakers as being particularly vulnerable to fuel poverty: disabled people and low-income families. In the UK, these groups are nominally prioritised within fuel poverty policy, but their complex situations are not always fully appreciated. Building on the theoretical foundations of energy justice, we present an inter-disciplinary dialogue that connects this approach with wider vulnerability research and domestic energy efficiency policy. Specifically, we discuss ‘within group’ heterogeneity (recognition justice), stakeholder engagement in policy and governance (procedural justice) and the overlap of multiple structural inequalities (distributional justice). In each section we illustrate the added value of combining justice and vulnerability conceptualisations by linking them to domestic energy efficiency schemes
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