1,325 research outputs found
Feedforward decoupling control method in grid-interfaced inverter
Recently, microgrid has been studied and applied widely all over the world. More and more experimental microgrids are being connected to the utility grid. This paper presents an improvement in the real and reactive power control of three-phase grid-interfaced inverter for microgrid applications. Based on the traditional PI feedback current control, the desirable values of P and Q can be achieved by controlling the currents in d-q stationary frame. Moreover, the feedforward control method also brings some advantages to the systems such as higher reliability and enhanced stability. One of the most important improvements is to decouple the real and reactive power, i.e. P and Q are controlled separately. In this paper, the controller with feedforward algorithm has been simulated and shows some promiscuous results. © 2013 Australasian Committee for Power Engineering (ACPE)
Planning ahead in public health? A qualitative study of the time horizons used in public health decision-making
<p>Abstract</p> <p>Background</p> <p>In order to better understand factors that influence decisions for public health, we undertook a qualitative study to explore issues relating to the time horizons used in decision-making.</p> <p>Methods</p> <p>Qualitative study using semi-structured interviews. 33 individuals involved in the decision making process around coronary heart disease were purposively sampled from the UK National Health Service (national, regional and local levels), academia and voluntary organizations. Analysis was based on the framework method using N-VIVO software. Interviews were transcribed, coded and emergent themes identified.</p> <p>Results</p> <p>Many participants suggested that the timescales for public health decision-making are too short. Commissioners and some practitioners working at the national level particularly felt constrained in terms of planning for the long-term. Furthermore respondents felt that longer term planning was needed to address the wider determinants of health and to achieve societal level changes. Three prominent 'systems' issues were identified as important drivers of short term thinking: the need to demonstrate impact within the 4 year political cycle; the requirement to 'balance the books' within the annual commissioning cycle and the disruption caused by frequent re-organisations within the health service. In addition respondents suggested that the tools and evidence base for longer term planning were not well established.</p> <p>Conclusion</p> <p>Many public health decision and policy makers feel that the timescales for decision-making are too short. Substantial systemic barriers to longer-term planning exist. Policy makers need to look beyond short-term targets and budget cycles to secure investment for long-term improvement in public health.</p
Default policies for global optimisation of noisy functions with severe noise
Global optimisation of unknown noisy functions is a daunting task that appears in domains ranging from games to control problems to meta-parameter optimisation for machine learning. We show how to incorporate heuristics to Stochastic Simultaneous Optimistic Optimization (STOSOO), a global optimisation algorithm that has very weak requirements from the function. In our case, heuristics come in the form of Covariance Matrix Adaptation Evolution Strategy (CMA-ES). The new algorithm, termed Guided STOSOO (STOSOO-G), combines the ability of CMA-ES for fast local convergence (due to the algorithm following the ânaturalâ gradient) and the global optimisation abilities of STOSOO. We compare all three algorithms in the âharderâ parts of the Comparing Continuous Optimisers on Black-Box Optimization Benchmarking benchmark suite, which provides a default set of functions for testing. We show that our approach keeps the best of both worlds, i.e. the almost optimal exploration/exploitation of STOSOO with the local optimisation strength of CMA-ES
G11.92-0.61 MM1: A Keplerian disc around a massive young proto-O star
The formation process of massive stars is not well understood, and
advancement in our understanding benefits from high resolution observations and
modelling of the gas and dust surrounding individual high-mass (proto)stars.
Here we report sub-arcsecond (<1550 au) resolution observations of the young
massive star G11.92-0.61 MM1 with the SMA and VLA. Our 1.3 mm SMA observations
reveal consistent velocity gradients in compact molecular line emission from
species such as CHCN, CHOH, OCS, HNCO, HCO, DCN and CHCHCN,
oriented perpendicular to the previously reported bipolar molecular outflow
from MM1. Modelling of the compact gas kinematics suggests a structure
undergoing rotation around the peak of the dust continuum emission. The
rotational profile can be well fit by a model of a Keplerian disc, including
infall, surrounding an enclosed mass of 30-60M, of which
2-3M is attributed to the disc. From modelling the CHCN emission,
we determine that two temperature components, of 150 K and 230 K, are required
to adequately reproduce the spectra. Our 0.9 and 3.0cm VLA continuum data
exhibit an excess above the level expected from dust emission; the full
centimetre-submillimetre wavelength spectral energy distribution of MM1 is well
reproduced by a model including dust emission, an unresolved hypercompact
H{\i}{\i} region, and a compact ionised jet. In combination, our results
suggest that MM1 is an example of a massive proto-O star forming via disc
accretion, in a similar way to that of lower mass stars.European Research Council (ERC-2013-ADG DISCSIM project (Grant ID: 341137), ERC-2011-ADG ECOGAL project (Grant ID: 291227)), Science and Technology Facilities Council (Grant ID: ST/M001296/1), Royal Astronomical Society (Undergraduate Research Bursary)This is the final version of the article. It first appeared from Oxford University Press via http://dx.doi.org/10.1093/mnras/stw191
Nitrides as ammonia synthesis catalysts and as potential nitrogen transfer reagents
In this article, an overview of the application of selected metal nitrides as ammonia synthesis catalysts is presented. The potential development of some systems into nitrogen transfer reagents is also described
Damage function for historic paper. Part II: Wear and tear
Background: As a result of use of library and archival documents, defined as reading with handling in the context of general access, mechanical degradation (wear and tear) accumulates. In contrast to chemical degradation of paper, the accumulation of wear and tear is less well studied. Previous work explored the threshold of mechanical degradation at which a paper document is no longer considered to be fit for the purpose of use by a reader, while in this paper we explore the rate of accumulation of such damage in the context of object handling. Results: The degree of polymerisation (DP) of historic paper of European origin from mid-19thâmid-20th Century was shown to affect the rate of accumulation of wear and tear. While at DP > 800, this accumulation no longer depends on the number of handlings (the process is random), a wear-out function could be developed for documents with DP between 300 and 800. For objects with DP < 300, one large missing piece (i.e. such that contains text) developed on average with each instance of handling, which is why we propose this DP value as a threshold value for safe handling. Conclusions: The developed model of accumulation of large missing pieces per number of handlings of a document depending on DP, enables us to calculate the time required for an object to become unfit for use by readers in the context of general access. In the context of the average frequency of document use at The UK National Archives (Kew), this period is 60 years for the category of papers with DP 300, and 450 years for papers with DP 500. At higher DP values, this period of time increases beyond the long-term planning horizon of 500 years, leading to the conclusion that for such papers, accumulation of wear and tear is not a significant collection management concern
Asymmetric triplex metallohelices with high and selective activity against cancer cells
Small cationic amphiphilic α-helical peptides are emerging as agents for the treatment of cancer and infection, but they are costly and display unfavourable pharmacokinetics. Helical coordination complexes may offer a three-dimensional scaffold for the synthesis of mimetic architectures. However, the high symmetry and modest functionality of current systems offer little scope to tailor the structure to interact with specific biomolecular targets, or to create libraries for phenotypic screens. Here, we report the highly stereoselective asymmetric self-assembly of very stable, functionalized metallohelices. Their anti-parallel head-to-head-to-tail âtriplexâ strand arrangement creates an amphipathic functional topology akin to that of the active sub-units of, for example, host-defence peptides and âp53. The metallohelices display high, structure-dependent toxicity to the human colon carcinoma cell-line HCT116 âp53++, causing dramatic changes in the cell cycle without DNA damage. They have lower toxicity to human breast adenocarcinoma cells (MDA-MB-468) and, most remarkably, they show no significant toxicity to the bacteria methicillin-resistant Staphylococcus aureus and Escherichia coli.
At a glanc
Short-term efficacy of physical interventions in osteoarthritic knee pain. A systematic review and meta-analysis of randomised placebo-controlled trials.
BACKGROUND: Treatment efficacy of physical agents in osteoarthritis of the knee (OAK) pain has been largely unknown, and this systematic review was aimed at assessing their short-term efficacies for pain relief. METHODS: Systematic review with meta-analysis of efficacy within 1-4 weeks and at follow up at 1-12 weeks after the end of treatment. RESULTS: 36 randomised placebo-controlled trials (RCTs) were identified with 2434 patients where 1391 patients received active treatment. 33 trials satisfied three or more out of five methodological criteria (Jadad scale). The patient sample had a mean age of 65.1 years and mean baseline pain of 62.9 mm on a 100 mm visual analogue scale (VAS). Within 4 weeks of the commencement of treatment manual acupuncture, static magnets and ultrasound therapies did not offer statistically significant short-term pain relief over placebo. Pulsed electromagnetic fields offered a small reduction in pain of 6.9 mm [95% CI: 2.2 to 11.6] (n = 487). Transcutaneous electrical nerve stimulation (TENS, including interferential currents), electro-acupuncture (EA) and low level laser therapy (LLLT) offered clinically relevant pain relieving effects of 18.8 mm [95% CI: 9.6 to 28.1] (n = 414), 21.9 mm [95% CI: 17.3 to 26.5] (n = 73) and 17.7 mm [95% CI: 8.1 to 27.3] (n = 343) on VAS respectively versus placebo control. In a subgroup analysis of trials with assumed optimal doses, short-term efficacy increased to 22.2 mm [95% CI: 18.1 to 26.3] for TENS, and 24.2 mm [95% CI: 17.3 to 31.3] for LLLT on VAS. Follow-up data up to 12 weeks were sparse, but positive effects seemed to persist for at least 4 weeks after the course of LLLT, EA and TENS treatment was stopped. CONCLUSION: TENS, EA and LLLT administered with optimal doses in an intensive 2-4 week treatment regimen, seem to offer clinically relevant short-term pain relief for OAK
The geographical distribution of lymphatic filariasis infection in Malawi
Mapping distribution of lymphatic filariasis (LF) is a prerequisite for planning national elimination programmes. Results from a nation wide mapping survey for lymphatic filariasis (LF) in Malawi are presented. Thirty-five villages were sampled from 23 districts excluding three districts (Karonga, Chikwawa and Nsanje) that had already been mapped and Likoma, an Island, where access was not possible in the time frame of the survey. Antigenaemia prevalence [based on immunochromatographic card tests (ICT)] ranged from 0% to 35.9%. Villages from the western side of the country and distant from the lake tended to be of lower prevalence. The exception was a village in Mchinji district on the Malawi-Zambia border where a prevalence of 18.2% was found. In contrast villages from lake shore districts [Salima, Mangochi, Balaka and Ntcheu (Bwanje valley)] and Phalombe had prevalences of over 20%
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