Steadfast in their ways: New England colonists, Indian wars, and the persistence of culture, 1675-1715

The Indian wars of early New England were traumatic events. During King Philip\u27s, King William\u27s, and Queen Anne\u27s Wars (1675 to 1715) dozens of towns sustained attacks, and English communities and their inhabitants were buffeted and challenged by the experience. The scholarship on colonial warfare and New England as a whole has focused on change and development that occurred as a result of these wars. War places great stress on individuals and societies, forcing them to act in new ways and often to reevaluate and abandon old habits. New Englanders and their communities did change dramatically as a result of repeated wars with the region\u27s natives and their French allies. Yet New Englanders were also resistant to change, and this persistence of core culture ideals is often as historians analyze the transformation of New England from colonies to provinces.;Beyond the extensive physical damage, the conflicts challenged the identities and values of English colonists in myriad ways. In the midst of battle, many men failed to live up to the expectations of their gender, while some women stepped beyond theirs to act in a manly fashion. Despite the troubling behavior of cowardly men and manly women, gender norms and roles in New England did not change under the pressures of Indian wars, in part due to the uncoordinated management by ecclesiastical and political leaders of the narratives of the conflicts. Alternately chastising and praising their constituents, leaders offered examples of proper behavior, reasserted control over amazons and viragos, and created larger-than-life heroes.;Indian raids forced hundreds of English settlers from their homes, putting great stress on towns and colonies and creating the dilemma of either aiding refugees (and abandoning the traditional insular nature of towns) or excluding and expelling them (failing John Winthrop\u27s exhortation to bind together). Historians argue that traditional aid through family and towns was incapable of meeting the demand. Instead, New England\u27s governments responded by relieving towns of this responsibility. However, this aid was actually limited and narrowly directed. Towns remained exclusive, gathering in those they were obliged to aid through familial or proprietary connections and allowing outsiders to remain only conditionally. Following the natural hierarchy of their community, refugees sought to support themselves before turning to family and friends, and sought town and colony aid only when traditional sources were exhausted.;Finally, in the midst of Indian wars, New Englanders often had to dispose of captured Indians. Having suffered grievously in the wars, New Englanders might have abandoned the law (albeit English law for Englishmen) and exacted revenge. Many prisoners suffered vigilante justice, and others faced servitude or public execution after a formal trial. New Englanders are rightly criticized for their actions, but while the colonists\u27 treatment of prisoners was uncivil by modern standards, when viewed through the context of the time, New England\u27s leaders tempered the rage of the people, and the colonies remained within bounds of tradition and law.;New Englanders resisted changes to the core cultural ideas and institutions of patriarchy, localized community, and morality based in English law. Though these notions of gender, community, and morality were battered by war, they survived and remained central to New England identity

Stability assessment of the (A)ATSR sea surface temperature climate dataset from the European Space Agency Climate Change Initiative

Sea surface temperature is a key component of the climate record, with multiple independent records giving confidence in observed changes. As part of the European Space Agencies (ESA) Climate Change Initiative (CCI) the satellite archives have been reprocessed with the aim of creating a new dataset that is independent of the in situ observations, and stable with no artificial drift (<0.1 K decade−1 globally) or step changes. We present a method to assess the satellite sea surface temperature (SST) record for step changes using the Penalized Maximal t Test (PMT) applied to aggregate time series. We demonstrated the application of the method using data from version EXP1.8 of the ESA SST CCI dataset averaged on a 7 km grid and in situ observations from moored buoys, drifting buoys and Argo floats. The CCI dataset was shown to be stable after ~1994, with minimal divergence (~0.01 K decade−1) between the CCI data and in situ observations. Two steps were identified due to the failure of a gyroscope on the ERS-2 satellite, and subsequent correction mechanisms applied. These had minimal impact on the stability due to having equal magnitudes but opposite signs. The statistical power and false alarm rate of the method were assessed

Investigating discrepancies between experimental solid-state NMR and GIPAW calculation : NC–N 13C and OH⋯O 1H chemical shifts in pyridinium fumarates and their cocrystals

An NMR crystallography analysis is presented for four solid-state structures of pyridine fumarates and their cocrystals, using crystal structures deposited in the Cambridge Crystallographic Data Centre, CCDC. Experimental one-dimensional, one-pulse 1H and 13C cross-polarisation (CP) magic-angle spinning (MAS) nuclear magnetic resonance (NMR) and two-dimensional 14N–1H heteronuclear multiple-quantum coherence MAS NMR spectra are compared with gauge-including projector augmented wave (GIPAW) calculations of the 1H and 13C chemical shifts and the 14N shifts that additionally depend on the quadrupolar interaction. Considering the high ppm (>10 ppm) 1H resonances, while there is good agreement (within 0.4 ppm) between experiment and GIPAW calculation for the hydrogen-bonded NH moieties, the hydrogen-bonded fumaric acid OH resonances are 1.2–1.9 ppm higher in GIPAW calculation as compared to experiment. For the cocrystals of a salt and a salt formed by 2-amino-5-methylpyridinium and 2-amino-6-methylpyridinium ions, a large discrepancy of 4.2 and 5.9 ppm between experiment and GIPAW calculation is observed for the quaternary ring carbon 13C resonance that is directly bonded to two nitrogens (in the ring and in the amino group). By comparison, there is excellent agreement (within 0.2 ppm) for the quaternary ring carbon 13C resonance directly bonded to the ring nitrogen for the salt and cocrystal of a salt formed by 2,6-lutidinium and 2,5-lutidine, respectively

Longitudinal qualitative evaluation of pharmacist integration into the urgent care setting

Purpose: To describe the most effective model for managing, educating, and training pharmacist advanced clinical practitioners (ACPs) in the urgent care center (UCC) setting, role evolution and how to measure their effectiveness. Participants and methods: Ethical approval was obtained to perform a qualitative longitudinal cohort study in three sites, with three pharmacists in each trained as ACPs from 2016 to 2017. ACP role, location, management, mentorship, and supervision were locally determined. ACPs attended focus groups (FGs) at 1 and 3 months (sites 1–3), 6 and 12 months (site 1 only), and the UCC staff were interviewed once with a topic guide regarding training, integration, role, and impact. Verbatim transcriptions were analyzed thematically. Results: Eight ACP FGs and 24 stakeholder interviews produced major themes of communication, management, education and training, role, and outcomes. Effective education, training, and integration required communication of role to address concerns regarding salary differentials, supportive management structure, and multi-professional learning. ACPs reported that the model of workplace training, experiential learning, and university-based education was appropriate. Training was better located in the minor injuries and general practitioner areas. Recommended measures of effectiveness included patient satisfaction and workload transfer. Conclusion: The education and training model was appropriate. Communication and management require careful consideration to ensure effective integration and role development. Pharmacists were better located initially in the minor illness rather than major trauma areas. Quality of patient experience resulting from the new role was important in addition to reassurance that the role represented a positive contribution to workload

Biodiversity Gains? The Debate on Changes in Local- vs Global-Scale Species Richness

Editorial: Do changes in biodiversity at local scales reflect the declines seen at global scales? This debate dates back at least 15 years..

The Copernicus surface velocity platform drifter with barometer and reference sensor for temperature (SVP-BRST): genesis, design, and initial results

To support calibration and validation of satel- lite sea surface temperature (SST) retrievals, over 60 high- resolution SST (HRSST) drifting buoys were deployed at sea between 2012 and 2017. Their data record is reviewed here. It is confirmed that sea state and immersion depth play an important role in understanding the data collected by such buoys and that the SST sensors need adequate insu- lation. In addition, calibration verification of three recovered drifters suggests that the sensor drift is low, albeit negative at around −0.01 K year−1. However, the statistical significance of these results is limited, and the calibration procedure could not be exactly reproduced, introducing additional uncertain- ties into this drift assessment. Based on lessons learnt from these initial buoys, a new sensor package for the Surface Velocity Platform with Barometer (SVP-B) was designed to serve calibration of SST retrievals by European Union’s Copernicus satellites. The novel sensor package includes an HRSST sensor calibrated by a metrology laboratory. The sensor includes a pressure probe to monitor immersion depth in calm water and acquires SST data at 1 Hz over a 5 min in- terval every hour. This enables the derivation of mean SST as well as several percentiles of the SST distribution. The HRSST sensor is calibrated with an uncertainty better than 0.01 K. Analysis of the data collected by two prototypes de- ployed in the Mediterranean Sea shows that the buoys are able to capture small-scale SST variations. These variations are found to be smaller when the sea state is well mixed and when the buoys are located within eddy cores. This affects the drifter SST data representativeness, which is an aspect of importance for optimal use of these data

Comprehensive review:Computational modelling of Schizophrenia

Computational modelling has been used to address: (1) the variety of symptoms observed in schizophrenia using abstract models of behavior (e.g. Bayesian models - top-down descriptive models of psychopathology); (2) the causes of these symptoms using biologically realistic models involving abnormal neuromodulation and/or receptor imbalance (e.g. connectionist and neural networks - bottom-up realistic models of neural processes). These different levels of analysis have been used to answer different questions (i.e. understanding behavioral vs. neurobiological anomalies) about the nature of the disorder. As such, these computational studies have mostly supported diverging hypotheses of schizophrenia's pathophysiology, resulting in a literature that is not always expanding coherently. Some of these hypotheses are however ripe for revision using novel empirical evidence.Here we present a review that first synthesizes the literature of computational modelling for schizophrenia and psychotic symptoms into categories supporting the dopamine, glutamate, GABA, dysconnection and Bayesian inference hypotheses respectively. Secondly, we compare model predictions against the accumulated empirical evidence and finally we identify specific hypotheses that have been left relatively under-investigated