To what extent is Denmark vulnerable to mineral supply shortage?

Mineral resources are building blocks of modern society and essential for progress and prosperity. Mankind has always depended on access to mineral raw materials, which have been a key factor for wealth, culture and development. Modern societies are characterised by a rapidly increasing demand for specialised mineral raw materials, determined by their stage of technological development, the number of consumers, and their standard of living. Generally, the availability of mineral raw materials has not, until recently, been considered an issue by the average consumer or by companies in the downstream end of the value chains, and mineral resources have not been part of the political agenda. In this context China’s control over rare-earth elements (REE) has been an eye opener to both industry and politicians worldwide, and has subsequently led to discussions about the possible exhaustion of finite resources and potential threats to the availability of raw materials caused by geopolitical tension and market restrictions

Chenodeoxycholic acid stimulates glucagon-like peptide-1 secretion in patients after Roux-en-Y gastric bypass

Postprandial secretion of glucagon‐like peptide‐1 (GLP‐1) is enhanced after Roux‐en‐Y gastric bypass (RYGB), but the precise molecular mechanisms explaining this remain poorly understood. Plasma concentrations of bile acids (BAs) increase after RYGB, and BAs may act as molecular enhancers of GLP‐1 secretion through activation of TGR5‐receptors. We aimed to evaluate GLP‐1 secretion after oral administration of the primary bile acid chenodeoxycholic acid (CDCA) and the secondary bile acid ursodeoxycholic acid (UDCA) (which are available for oral use) in RYGB‐operated participants. Eleven participants (BMI 29.1 ± 1.2, age 37.0 ± 3.2 years, time from RYGB 32.3 ± 1.1 months, weight loss after RYGB 37.0 ± 3.1 kg) were studied in a placebo‐controlled, crossover‐study. On three different days, participants ingested (1) placebo (water), (2) UDCA 750 mg, (3) CDCA 1250 mg (highest recommended doses). Oral intake of CDCA increased plasma concentrations of GLP‐1, C‐peptide, glucagon, peptide YY, neurotensin, total bile acids, and fibroblast growth factor 19 significantly compared with placebo (all P < 0.05 for peak and positive incremental area‐under‐the‐curve (piAUC)). All plasma hormone concentrations were unaffected by UDCA. Neither UDCA nor CDCA changed glucose, cholecystokinin or glucose‐dependent insulinotropic polypeptide (GIP) concentrations. In conclusion, our findings demonstrate that the primary bile acid chenodeoxycholic acid is able to enhance secretion of gut hormones when administered orally in RYGB‐operated patients—even in the absence of nutrients

The Swarm Initial Field Model for the 2014 geomagnetic field

Data from the first year of ESA's Swarm constellation mission are used to derive the Swarm Initial Field Model (SIFM), a new model of the Earth's magnetic field and its time variation. In addition to the conventional magnetic field observations provided by each of the three Swarm satellites, explicit advantage is taken of the constellation aspect by including east-west magnetic intensity gradient information from the lower satellite pair. Along-track differences in magnetic intensity provide further information concerning the north-south gradient. The SIFM static field shows excellent agreement (up to at least degree 60) with recent field models derived from CHAMP data, providing an initial validation of the quality of the Swarm magnetic measurements. Use of gradient data improves the determination of both the static field and its secular variation, with the mean misfit for east-west intensity differences between the lower satellite pair being only 0.12 nT

Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage

Antimicrobial resistance (AMR) is a serious threat to global public health, but obtaining representative data on AMR for healthy human populations is difficult. Here, we use meta-genomic analysis of untreated sewage to characterize the bacterial resistome from 79 sites in 60 countries. We find systematic differences in abundance and diversity of AMR genes between Europe/North-America/Oceania and Africa/Asia/South-America. Antimicrobial use data and bacterial taxonomy only explains a minor part of the AMR variation that we observe. We find no evidence for cross-selection between antimicrobial classes, or for effect of air travel between sites. However, AMR gene abundance strongly correlates with socio-economic, health and environmental factors, which we use to predict AMR gene abundances in all countries in the world. Our findings suggest that global AMR gene diversity and abundance vary by region, and that improving sanitation and health could potentially limit the global burden of AMR. We propose metagenomic analysis of sewage as an ethically acceptable and economically feasible approach for continuous global surveillance and prediction of AMR.Peer reviewe

Characterisation of incinerator bottom ash from a Danish waste-to-energy plant: a step towards closing the material cycle

The UN Sustainable Development Goal 12, regarding responsible production and consumption of raw materials, guides ongoing international efforts to enhance sustainability in all parts of the mineral sector. Of particular interest, is improving the recyclability of secondary waste streams and thereby increasing the efficiency of recycling end-of-life products. Municipal solid waste – residual waste from household and industry – constitutes one of these secondary streams. It is typically incinerated in waste-to-energy plants producing two types of waste streams that carry a raw material resource potential: incinerator bottom ash (IBA) and incinerator fly ash (IFA). IBA is of particular interest in the recycling industry, where it is commonly recycled to produce three main fractions: (i) ferrous material, (ii) non-ferrous material, and (iii) residual slag. In most cases the two metal fractions are separated further downstream in the value chain, prior to smelting. The residual, non-magnetic fraction (typically 0–45 mm) is used mainly as construction aggregate. Improvements in the efficiency of existing separation technologies are still being made, but less effort is focussed on characterising the fundamental composition and mineral resource potential of IBA. For this reason, the Urban-X project was launched by the Geological Survey of Denmark and Greenland (GEUS) to characterise the composition and resource potential of various waste streams at Amager Bakke waste-to-energy plant in Copenhagen, Denmark. This paper discusses some of the main outcomes of the Urban-X project with respect to IBA, and a full analysis of all waste streams analysed at Amager Bakke is available in Clausen&nbsp;et al. 2019

To what extent is Denmark vulnerable to mineral supply shortage?

Mineral resources are building blocks of modern society and essential for progress and prosperity. Mankind has always depended on access to mineral raw materials, which have been a key factor for wealth, culture and development. Modern societies are characterised by a rapidly increasing demand for specialised mineral raw materials, determined by their stage of technological development, the number of consumers, and their standard of living. Generally, the availability of mineral raw materials has not, until recently, been considered an issue by the average consumer or by companies in the downstream end of the value chains, and mineral resources have not been part of the political agenda. In this context China’s control over rare-earth elements (REE) has been an eye opener to both industry and politicians worldwide, and has subsequently led to discussions about the possible exhaustion of finite resources and potential threats to the availability of raw materials caused by geopolitical tension and market restrictions