Separability and Killing Tensors in Kerr-Taub-NUT-de Sitter Metrics in Higher Dimensions

A generalisation of the four-dimensional Kerr-de Sitter metrics to include a NUT charge is well known, and is included within a class of metrics obtained by Plebanski. In this paper, we study a related class of Kerr-Taub-NUT-de Sitter metrics in arbitrary dimensions D \ge 6, which contain three non-trivial continuous parameters, namely the mass, the NUT charge, and a (single) angular momentum. We demonstrate the separability of the Hamilton-Jacobi and wave equations, we construct a closely-related rank-2 Staeckel-Killing tensor, and we show how the metrics can be written in a double Kerr-Schild form. Our results encompass the case of the Kerr-de Sitter metrics in arbitrary dimension, with all but one rotation parameter vanishing. Finally, we consider the real Euclidean-signature continuations of the metrics, and show how in a limit they give rise to certain recently-obtained complete non-singular compact Einstein manifolds.Comment: Author added, title changed, references added, focus of paper changed to Killing tensors and separability. Latex, 13 page

Spinor Fields and Symmetries of the Spacetime

In the background of a stationary black hole, the "conserved current" of a particular spinor field always approaches the null Killing vector on the horizon. What's more, when the black hole is asymptotically flat and when the coordinate system is asymptotically static, then the same current also approaches the time Killing vector at the spatial infinity. We test these results against various black hole solutions and no exception is found. The spinor field only needs to satisfy a very general and simple constraint.Comment: 19 page

General Metrics of G_2 Holonomy and Contraction Limits

We obtain first-order equations for G_2 holonomy of a wide class of metrics with S^3\times S^3 principal orbits and SU(2)\times SU(2) isometry, using a method recently introduced by Hitchin. The new construction extends previous results, and encompasses all previously-obtained first-order systems for such metrics. We also study various group contractions of the principal orbits, focusing on cases where one of the S^3 factors is subjected to an Abelian, Heisenberg or Euclidean-group contraction. In the Abelian contraction, we recover some recently-constructed G_2 metrics with S^3\times T^3 principal orbits. We obtain explicit solutions of these contracted equations in cases where there is an additional U(1) isometry. We also demonstrate that the only solutions of the full system with S^3\times T^3 principal orbits that are complete and non-singular are either flat R^4 times T^3, or else the direct product of Eguchi-Hanson and T^3, which is asymptotic to R^4/Z_2\times T^3. These examples are in accord with a general discussion of isometric fibrations by tori which, as we show, in general split off as direct products. We also give some (incomplete) examples of fibrations of G_2 manifolds by associative 3-tori with either T^4 or K3 as base.Comment: Latex, 27 page

Horava-Witten Stability: eppur si muove

We construct exact time-dependent solutions of the supergravity equations of motion in which two initially non-singular branes, one with positive and the other with negative tension, move together and annihilate each other in an all-enveloping spacetime singularity. Among our solutions are the Horava-Witten solution of heterotic M-theory and a Randall-Sundrum I type solution, both of which are supersymmetric, i.e. BPS, in the time-independent case. In the absence of branes our solutions are of Kasner type, and the source of instability may ascribed to a failure to stabilise some of the modulus fields of the compactification. It also raises questions about the viability of models based on some sorts of negative tension brane.Comment: Latex, 22 pages, extended discussion of the global spacetime structure, and reference adde

Kahler Potential for M-theory on a G_2 Manifold

We compute the moduli Kahler potential for M-theory on a compact manifold of G_2 holonomy in a large radius approximation. Our method relies on an explicit G_2 structure with small torsion, its periods and the calculation of the approximate volume of the manifold. As a verification of our result, some of the components of the Kahler metric are computed directly by integration over harmonic forms. We also discuss the modification of our result in the presence of co-dimension four singularities and derive the gauge-kinetic functions for the massless gauge fields that arise in this case.Comment: 31 pages, Latex. Altered discussion of truncation of field content, some typos corrected and references added. Version to appear in Phys. Rev .

Charged rotating dilaton black branes in AdS universe

We present the metric for the $(n+1)$-dimensional charged rotating dilaton black branes with cylindrical or toroidal horizons in the background of anti-de Sitter spacetime. We find the suitable counterterm which removes the divergences of the action in the presence of the dilaton potential in all higher dimensions. We plot the Penrose diagrams of the spacetime and reveal that the spacetime geometry crucially modifies in the presence of the dilaton field. The conserved and thermodynamic quantities of the black branes are also computed.Comment: 13 pages, 3 figures, to appear in Gen. Relat. Gravi

Slowly rotating charged black holes in anti-de Sitter third order Lovelock gravity

In this paper, we study slowly rotating black hole solutions in Lovelock gravity (n=3). These exact slowly rotating black hole solutions are obtained in uncharged and charged cases, respectively. Up to the linear order of the rotating parameter a, the mass, Hawking temperature and entropy of the uncharged black holes get no corrections from rotation. In charged case, we compute magnetic dipole moment and gyromagnetic ratio of the black holes. It is shown that the gyromagnetic ratio keeps invariant after introducing the Gauss-Bonnet and third order Lovelock interactions.Comment: 14 pages, no figur

Tachyon Kinks on Unstable Dp-branes

In the context of tachyon effective theory coupled to Born-Infeld electromagnetic fields, we obtain all possible singularity-free static flat configurations of codimension one on unstable Dp-branes. Computed tension and string charge density suggest that the obtained kinks are D(p-1) or D(p-1)F1-branes.Comment: 22pages, LaTeX2e, 7figure

Higher Dimensional Charged Rotating Dilaton Black Holes

In this paper, we present the metric for the $n$-dimensional charged slowly rotating dilaton black hole with $N = [(n -1)/2]$ independent rotation parameters, associated with $N$ orthogonal planes of rotation in the background of asymptotically flat and asymptotically (anti)-de Sitter spacetime. The mass, angular momentum and the gyromagnetic ratio of such a black hole are determined for the arbitrary values of the dilaton coupling constant. We find that the gyromagnetic ratio crucially depends on the dilaton coupling constant, $\alpha$, and decreases with increasing $\alpha$ in any dimension.Comment: 15 pages, 1 figur

Cardiomyocytes from human pluripotent stem cells: from laboratory curiosity to industrial biomedical platform

Cardiomyocytes from human pluripotent stem cells (hPSCs-CMs) could revolutionise biomedicine. Global burden of heart failure will soon reach USD $90bn, while unexpected cardiotoxicity underlies 28% of drug withdrawals. Advances in hPSC isolation, Cas9/CRISPR genome engineering and hPSC-CM differentiation have improved patient care, progressed drugs to clinic and opened a new era in safety pharmacology. Nevertheless, predictive cardiotoxicity using hPSC-CMs contrasts from failure to almost total success. Since this likely relates to cell immaturity, efforts are underway to use biochemical and biophysical cues to improve many of the ~ 30 structural and functional properties of hPSC-CMs towards those seen in adult CMs. Other developments needed for widespread hPSC-CM utility include subtype specification, cost reduction of large scale differentiation and elimination of the phenotyping bottleneck. This review will consider these factors in the evolution of hPSC-CM technologies, as well as their integration into high content industrial platforms that assess structure, mitochondrial function, electrophysiology, calcium transients and contractility. This article is part of a Special Issue entitled: Cardiomyocyte Biology: Integration of Developmental and Environmental Cues in the Heart edited by Marcus Schaub and Hughes Abriel