Verbal Communication Skills Requirements for Information Systems Professionals

The role of information systems (IS) professionals in organizations has changed through the years, from one who works mostly with technically oriented peers, to one who spends a significant amount of time interacting with people who are involved in the functional areas of the organization. In many organizations, IS professionals are assigned permanently to the user area and they are expected to not only be technically competent, but also be competent in the user\u27s area. This move of IS professionals to the functional areas necessitates that they communicate more with the functional users whose IS needs they are fulfilling. The users, on the other hand, are also required to interact and communicate more with the IS people. With the move toward distributed IS, users are becoming more involved in the specification, design and sometimes even construction of their own systems. It is therefore imperative that analysts and users be able to communicate with each other unequivocally, so that the systems are specified and developed properly. This research investigated the verbal communication skills requirements for IS practicing professionals and new university graduates. A survey was used for data collection. It was sent to IS professionals in several large organizations, that represented the industry in general. A nearly perfect response rate was achieved. The findings are useful for both IS professionals and university programs. Organizations can use the findings to identify areas of weaknesses in the skills of their IS personnel and eliminate them with continuing education. Universities can use the findings to identify skills that they may not be currently emphasizing in their curricula and make necessary adjustments

Two Years of Relationship-Focused Mentoring for First Nations, Metis, and Inuit Adolescents: Promoting Positive Mental Health

First Nations, Métis, and Inuit (FNMI) youth are disproportionately affected by a range of negative health outcomes including poor emotional and psychosocial well-being. At the same time, there is increasing awareness of culturally-specific protective factors for these youth, such as cultural connectedness and identity. This article reports the findings of a mixed-methods, exploratory longitudinal study on the effects of a culturally-relevant school-based mentoring program for FNMI youth that focuses on promoting mental well-being and the development of cultural identity. Participants included a cohort of FNMI adolescents whom we tracked across the transition from elementary to secondary school. We utilized data from annual surveys (n = 105) and a subset of youth whom we interviewed (n = 28). Quantitative analyses compared youth who participated in 1 or 2 years of mentoring programs with those who did not participate. At Wave 3, the 2-year mentoring group demonstrated better mental health and improved cultural identity, accounting for Wave 1 functioning. These results were maintained when sex and school climate were accounted for in the models. Sex did not emerge as a significant moderator; however, post hoc analyses with simple slopes indicated that the mentoring program benefited girls more than boys for both outcomes. Interview data were coded and themed through a multi-phase process, and revealed that the mentoring program helped participants develop their intrapersonal and interpersonal skills, and enhanced their cultural and healthy relationships knowledge base. Collectively, the quantitative and qualitative components of this study identify multiple years of culturally-relevant mentoring as a promising approach for promoting well-being among FNMI youth

Landau-Ginzburg/Calabi-Yau correspondence, global mirror symmetry and Orlov equivalence

We show that the Gromov-Witten theory of Calabi-Yau hypersurfaces matches, in genus zero and after an analytic continuation, the quantum singularity theory (FJRW theory) recently introduced by Fan, Jarvis and Ruan following ideas of Witten. Moreover, on both sides, we highlight two remarkable integral local systems arising from the common formalism of Gamma-integral structures applied to the derived category of the hypersurface {W=0} and to the category of graded matrix factorizations of W. In this setup, we prove that the analytic continuation matches Orlov equivalence between the two above categories.Comment: 72pages, v2: Appendix B and references added. Typos corrected, v3: several mistakes corrected, final versio

Analysis of Synthetic Monodisperse Polysaccharides by Wide Mass Range Ultrahigh-Resolution MALDI Mass Spectrometry

Carbohydrates, such as oligo- and polysaccharides, are highly abundant biopolymers that are involved in numerous processes. The study of their structure and functions is commonly based on a material that is isolated from complex natural sources. However, a more precise analysis requires pure compounds with well-defined structures that can be obtained from chemical or enzymatic syntheses. Novel synthetic strategies have increased the accessibility of larger monodisperse polysaccharides, posing a challenge to the analytical methods used for their molecular characterization. Here, we present wide mass range ultrahigh-resolution matrix-assisted laser desorption/ionization (MALDI) Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry (MS) as a powerful platform for the analysis of synthetic oligo- and polysaccharides. Synthetic carbohydrates 16-, 64-, 100-, and 151-mers were mass analyzed and characterized by MALDI in-source decay FT-ICR MS. Detection of fragment ions generated from glycosidic bond cleavage (or cross-ring cleavage) provided information of the monosaccharide content and the linkage type, allowing for the corroboration of the carbohydrate compositions and structures

Magnetic resonance imaging findings in bipartite medial cuneiform – a potential pitfall in diagnosis of midfoot injuries: a case series

<p>Abstract</p> <p>Introduction</p> <p>The bipartite medial cuneiform is an uncommon developmental osseous variant in the midfoot. To our knowledge, Magnetic Resonance Imaging (MRI) characteristics of a non-symptomatic bipartite medial cuneiform have not been described in the orthopaedic literature. It is important for orthopaedic foot and ankle surgeons, musculoskeletal radiologists, and for podiatrists to identify this osseous variant as it may be mistakenly diagnosed as a fracture or not recognized as a source of non-traumatic or traumatic foot pain, which may sometimes even require surgical treatment.</p> <p>Case presentations</p> <p>In this report, we describe the characteristics of three cases of bipartite medial cuneiform on Magnetic Resonance Imaging and contrast its appearance to that of a medial cuneiform fracture.</p> <p>Conclusion</p> <p>A bipartite medial cuneiform is a rare developmental anomaly of the midfoot and may be the source of midfoot pain. Knowledge about its characteristic appearance on magnetic resonance imaging is important because it is a potential pitfall in diagnosis of midfoot injuries.</p

Tau-Structure for the Double Ramification Hierarchies

In this paper we continue the study of the double ramification hierarchy of Buryak (Commun Math Phys 336(3):1085–1107, 2015). After showing that the DR hierarchy satisfies tau-symmetry we define its partition function as the (logarithm of the) tau-function of the string solution and show that it satisfies various properties (string, dilaton, and divisor equations plus some important degree constraints). We then formulate a stronger version of the conjecture from Buryak (2015): for any semisimple cohomological field theory, the Dubrovin–Zhang and double ramification hierarchies are related by a normal [i.e. preserving the tau-structure (Dubrovin et al. in Adv Math 293:382–435, 2016)] Miura transformation which we completely identify in terms of the partition function of the CohFT. In fact, using only the partition functions, the conjecture can be formulated even in the non-semisimple case (where the Dubrovin–Zhang hierarchy is not defined). We then prove this conjecture for various CohFTs (trivial CohFT, Hodge class, Gromov–Witten theory of CP¹, 3-, 4- and 5-spin classes) and in genus 1 for any semisimple CohFT. Finally we prove that the higher genus part of the DR hierarchy is basically trivial for the Gromov–Witten theory of smooth varieties with non-positive first Chern class and their analogue in Fan–Jarvis–Ruan–Witten quantum singularity theory (Fan et al. in Ann Math 178(1):1–106, 2013)

Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology

Atypical antipsychotic drugs have revolutionized the treatment of schizophrenia and related disorders. The current clinically approved atypical antipsychotic drugs are characterized by having relatively low affinities for D2-dopamine receptors and relatively high affinities for 5-HT2A serotonin receptors (5-HT, 5-hydroxytryptamine (serotonin)). Aripiprazole (OPC-14597) is a novel atypical antipsychotic drug that is reported to be a high-affinity D2-dopamine receptor partial agonist. We now provide a comprehensive pharmacological profile of aripiprazole at a large number of cloned G protein-coupled receptors, transporters, and ion channels. These data reveal a number of interesting and potentially important molecular targets for which aripiprazole has affinity. Aripiprazole has highest affinity for h5-HT2B-, hD2L-, and hD3-dopamine receptors, but also has significant affinity (5–30 nM) for several other 5-HT receptors (5-HT1A, 5-HT2A, 5-HT7), as well as α1A-adrenergic and hH1-histamine receptors. Aripiprazole has less affinity (30–200 nM) for other G protein-coupled receptors, including the 5-HT1D, 5-HT2C, α1B-, α2A-, α2B-, α2C-, β1-, and β2-adrenergic, and H3-histamine receptors. Functionally, aripiprazole is an inverse agonist at 5-HT2B receptors and displays partial agonist actions at 5-HT2A, 5-HT2C, D3, and D4 receptors. Interestingly, we also discovered that the functional actions of aripiprazole at cloned human D2-dopamine receptors are cell-type selective, and that a range of actions (eg agonism, partial agonism, antagonism) at cloned D2-dopamine receptors are possible depending upon the cell type and function examined. This mixture of functional actions at D2-dopamine receptors is consistent with the hypothesis proposed by Lawler et al (1999) that aripiprazole has ‘functionally selective’ actions. Taken together, our results support the hypothesis that the unique actions of aripiprazole in humans are likely a combination of ‘functionally selective’ activation of D2 (and possibly D3)-dopamine receptors, coupled with important interactions with selected other biogenic amine receptors—particularly 5-HT receptor subtypes (5-HT1A, 5-HT2A)

Global hybrids from the semiclassical atom theory satisfying the local density linear response

We propose global hybrid approximations of the exchange-correlation (XC) energy functional which reproduce well the modified fourth-order gradient expansion of the exchange energy in the semiclassical limit of many-electron neutral atoms and recover the full local density approximation (LDA) linear response. These XC functionals represent the hybrid versions of the APBE functional [Phys. Rev. Lett. 106, 186406, (2011)] yet employing an additional correlation functional which uses the localization concept of the correlation energy density to improve the compatibility with the Hartree-Fock exchange as well as the coupling-constant-resolved XC potential energy. Broad energetical and structural testings, including thermochemistry and geometry, transition metal complexes, non-covalent interactions, gold clusters and small gold-molecule interfaces, as well as an analysis of the hybrid parameters, show that our construction is quite robust. In particular, our testing shows that the resulting hybrid, including 20\% of Hartree-Fock exchange and named hAPBE, performs remarkably well for a broad palette of systems and properties, being generally better than popular hybrids (PBE0 and B3LYP). Semi-empirical dispersion corrections are also provided.Comment: 12 pages, 4 figure