Survey of clostridium difficile infection surveillance systems in Europe, 2011

To develop a European surveillance protocol for Clostridium difficile infection (CDI), existing national CDI surveillance systems were assessed in 2011. A web-based electronic form was provided for all national coordinators of the European CDI Surveillance Network (ECDIS-Net). Of 35 national coordinators approached, 33 from 31 European countries replied. Surveillance of CDI was in place in 14 of the 31 countries, comprising 18 different nationwide systems. Three of 14 countries with CDI surveillance used public health notification of cases as the route of reporting, and in another three, reporting was limited to public health notification of cases of severe CDI. The CDI definitions published by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the European Centre for Disease Prevention and Control (ECDC) were widely used, but there were differing definitions to distinguish between communityand healthcare-associated cases. All CDI surveillance systems except one reported annual national CDI rates (calculated as number of cases per patient-days). Only four surveillance systems regularly integrated microbiological data (typing and susceptibility testing results). Surveillance methods varied considerably between countries, which emphasises the need for a harmonised European protocol to allow consistent monitoring of the CDI epidemiology at European level. The results of this survey were used to develop a harmonised EU-wide hospital-based CDI surveillance protocol

Air rage from the sharp end:cabin crew perspectives on disruptive passenger behaviour in Europe and its impact on occupational safety and well-being

Disruptive passenger behaviour (DPB) incidents spiked during the COVID-19 pandemic period, compromising the safety of commercial flights on a daily basis. This qualitative semi-structured interview study examined the perceived triggering factors and motivations for DPB and the subsequent impact of DPB upon cabin crew well-being and safety. Twenty-four European cabin crew disclosed experiences, subjective observations of perpetrator traits, assessment of DPB development and information regarding their well-being and perceived safety. Thematic analysis revealed that the perceived frequency of DPB had increased, driven by an accumulation of pandemic-related factors - such as enforcing mask wearing amongst intoxicated passengers. DPB was found to decrease resilience and spur maladaptive coping strategies in crew. Suggested enhancements to current DPB mitigation consisted of stricter punishment for DPB as a deterrent, alcohol bans and higher quality training. These findings can inform decision-makers' efforts to support cabin crew well-being and create safer cabin workplaces in the future

Seismic evidence for thermal runaway during intermediate-depth earthquake rupture

Intermediate-depth earthquakes occur at depths where temperatures and pressures exceed those at which brittle failure is expected. There are two leading candidates for the physical mechanism behind these earthquakes: dehydration embrittlement and self-localizing thermal shear runaway. A complete energy budget for a range of earthquake sizes can help constrain whether either of these mechanisms might play a role in intermediate-depth earthquake rupture. The combination of high stress drop and low radiation efficiency that we observe for M[subscript w] 4–5 earthquakes in the Bucaramanga Nest implies a temperature increase of 600–1000°C for a centimeter-scale layer during earthquake failure. This suggests that substantial shear heating, and possibly partial melting, occurs during intermediate-depth earthquake failure. Our observations support thermal shear runaway as the mechanism for intermediate-depth earthquakes, which would help explain differences in their behavior compared to shallow earthquakes.National Science Foundation (U.S.) (Grant EAR-1045684

Малый и средний бизнес в Республике Беларусь: состояние и тенденции развития

В данной статье проведён анализ структуры, состояния и роли малого и среднего бизнеса, разработаны основные направления по развитию данного сегмента экономики в Республике Беларусь на современном этапе

Sharp thermal transition in the forearc mantle wedge as a consequence of nonlinear mantle wedge flow

Author Posting. © American Geophysical Union, 2011. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Geophysical Research Letters 38 (2011): L13308, doi:10.1029/2011GL047705.In the forearc mantle wedge, the thermal field depends strongly on slab-driven mantle wedge flow. The flow is in turn affected by the thermal field via the temperature dependence of mantle rheology. Using thermal modeling, we show that the nonlinear feedback between the thermal and flow fields always leads to complete stagnation of the mantle wedge over a shallow, weakened part of the slab-mantle interface and an abrupt onset of mantle flow further down-dip. The abrupt increase in flow velocity leads to a sharp thermal transition from a cold stagnant to a hot flowing part of the wedge. This sharp thermal transition is inherent to all subduction zones, explaining a commonly observed sharp arc-ward increase in seismic attenuation.This research was partially supported by National Science Foundation through a MARGINS postdoctoral fellowship (NSF OCE‐0840800) and by Natural Environment Research Council

Ocular Vaccinia Infection in Laboratory Worker, Philadelphia, 2004

We report a case of ocular vaccinia infection in an unvaccinated laboratory worker. The patient was infected by a unique strain used in an experiment performed partly outside a biosafety cabinet. Vaccination should continue to be recommended, but laboratories with unvaccinated workers should also implement more stringent biosafety practices

Measurement of in vitro cardiac deformation by means of 3D digital image correlation and ultrasound 2D speckle-tracking echocardiography

Ultrasound-based 2D speckle-tracking echocardiography (US-2D-STE) is increasingly used to assess the functionality of the heart. In particular, the analysis of cardiac strain plays an important role in the identification of several cardiovascular diseases. However, this imaging technique presents some limitations associated with its operating principle that result in low accuracy and reproducibility of the measurement. In this study, an experimental framework for multimodal strain imaging in an in vitro porcine heart was developed. Specifically, the aim of this work was to analyse displacement and strain in the heart by means of 3D digital image correlation (3D-DIC) and US-2D-STE. Over a single cardiac cycle, displacement values obtained from the two techniques were in strong correlation, although systematically larger displacements were observed with 3D-DIC. Notwithstanding an absolute comparison of the strain measurements was not possible to achieve between the two methods, maximum principal strain directions computed with 3D-DIC were consistent with the longitudinal and circumferential strain distribution measured with US-2D-STE. 3D-DIC confirmed its high repeatability in quantifying displacement and strain over multiple cardiac cycles, unlike US-2D-STE which is affected by accumulated errors over time (i.e. drift). To conclude, this study demonstrates the potential of 3D-DIC to perform dynamic measurement of displacement and strain during heart deformations and supports future applications of this method in ex vivo beating heart platforms, which replicate more fully the complex contraction of the heart

The rheology of banded iron formation: constraints from axial compression experiments

Samples of Banded Iron Formation (BIF) with different quartz and hematite contents were deformed in axial compression experiments in a Griggs-type apparatus, at T = 900ºC, P =1.5 GPa and strain rates of 10-5 and 10-6 s-1. The aim is to investigate the mineral phase that controls the rheology of multi-phase rocks and to determine the processes that control the observed rock strength. BIF samples from Quadrilátero Ferrífero region-Brazil were cored perpendicular to the foliation, which is defined by parallel bands of quartz and iron oxide. Sample strength decreases with increasing hematite content and decreasing strain rate. At a strain rate of 10-5 s-1, samples with well-developed compositional banding showed higher strength. At the slower strain rate of 10-6 s-1 no difference between samples with or without compositional banding is observed. For comparison, at 10-6 s-1, the highest quartz content sample is as weak as the highest hematite content sample at 10-5 s-1. Strain is localized in hematite-rich layers. One intriguing observation is that quartz grains within the more deformed hematite-rich bands show more evidence for crystal-plastic deformation than grains in quartz-rich bands