62 research outputs found
Perceived Nonwork Constraints and Withdrawal Intention among Expatriates during the COVID-19 Pandemic: Moderating Role of Resilience and Marital Status
- Publication venue
- Behavioral Science Research Institute, Srinakharinwirot University
- Publication date
- 01/01/2023
- Field of study
The COVID-19 pandemic has posed a considerable threat to the well-being of expatriates, which can be seriously exacerbated by both work- and nonwork-related factors. Since restrictions were introduced worldwide, expatriates find it more challenging to integrate into their organizations and local societies. This study mainly aimed to examine if resilience and marital status could affect the perceptions of nonwork constraints and withdrawal intentions among expatriates during the pandemic. Data collected from a sample of 205 expatriates living and working in Malaysia was analyzed using partial least squares-structural equation modeling. The results showed the positive and direct effect of perceived nonwork constraints on withdrawal intention (β = .29, p = .30). Using the two-stage moderation analysis, the results indicated the significant moderating effect of marital status on the relationship between perceived nonwork constraints and withdrawal intention (β = -.14, p = .04). However, the results did not substantiate the moderating effect of resilience on the relationship between perceived nonwork constraints and withdrawal intention (β = .16, p = .07). This research contributes to behavioral science knowledge about global mobility by applying spillover theory and the conservation of resources theory in the context of a medical emergency like the COVID-19 crisis. Notwithstanding ongoing obstacles caused by the global pandemic, the research findings could provide implications for human resource practitioners to improve work behavior among expatriates by considering their nonwork aspects and marital status
Detecting Signals of Disproportionate Reporting from Singapore's Spontaneous Adverse Event Reporting System: An Application of the Sequential Probability Ratio Test.
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 28/04/2017
- Field of study
INTRODUCTION: The ability to detect safety concerns from spontaneous adverse drug reaction reports in a timely and efficient manner remains important in public health. OBJECTIVE: This paper explores the behaviour of the Sequential Probability Ratio Test (SPRT) and ability to detect signals of disproportionate reporting (SDRs) in the Singapore context. METHODS: We used SPRT with a combination of two hypothesised relative risks (hRRs) of 2 and 4.1 to detect signals of both common and rare adverse events in our small database. We compared SPRT with other methods in terms of number of signals detected and whether labelled adverse drug reactions were detected or the reaction terms were considered serious. The other methods used were reporting odds ratio (ROR), Bayesian Confidence Propagation Neural Network (BCPNN) and Gamma Poisson Shrinker (GPS). RESULTS: The SPRT produced 2187 signals in common with all methods, 268 unique signals, and 70 signals in common with at least one other method, and did not produce signals in 178 cases where two other methods detected them, and there were 403 signals unique to one of the other methods. In terms of sensitivity, ROR performed better than other methods, but the SPRT method found more new signals. The performances of the methods were similar for negative predictive value and specificity. CONCLUSIONS: Using a combination of hRRs for SPRT could be a useful screening tool for regulatory agencies, and more detailed investigation of the medical utility of the system is merited
Development and novel therapeutics in hepatocellular carcinoma: a review
- Author
- Publication venue
- 'Dove Medical Press Ltd.'
- Publication date
- Field of study
Women with endometriosis have higher comorbidities: Analysis of domestic data in Taiwan
- Author
- Chan Chia-Hao
- Chang Cheng-Chang
- Chang Chih-Long
- Chang Shing-Jyh
- Chang Ting-Chen
- Chang Wei-Chun
- Chang Wen-Chun
- Chang Wen-Hsun
- Chang Yen-Hou
- Chang Yi
- Chao Hsiang-Tai
- Chao Kuan-Chong
- Chen Chih-Ping
- Chen Chih-Yao
- Chen Chii-Hou
- Chen Ching-Hui
- Chen Jen-Ruei
- Chen Kuo-Hu
- Chen Ruey-Jian
- Chen San-Nung
- Chen Tze-Chien
- Chen Tze-Ho
- Chen Yi-Jen
- Chiang An-Jen
- Chiou Jyh-Shin
- Chow Song-Nan
- Chu Ching-Chuang
- Chuang Chi-Mu
- Chuang Fei-Chi
- Fu Hung-Chun
- Ho Chi-Hong
- Horng Huann-Cheng
- Hsiao Sheng-Mou
- Hsieh Ching-Hung
- Hsu Shih-Tien
- Hsu Yen-Mei
- Huang Ben-Shian
- Huang Chen-Yu
- Huang Jian-Pei
- Huang Kuan-Hui
- Huang Kuo-Feng
- Huang Lee-Wen
- Huang Ming-Chao
- Huang Shu-Yun
- Hung Jeng-Hsiu
- Hung Man-Jung
- Hung Yao-Ching
- Jiang Ling-Yu
- Ju Fong-Yuan
- Ke Yu-Min
- Kung Fu-Tsai
- Lai Hung-Cheng
- Lai Tsung-Hsuan
- Lee Fa-Kung
- Lee Na-Rong
- Lee Wen-Ling
- Li Hsin-Yang
- Li Ju-Yueh
- Li Yiu-Tai
- Lien Yih-Ron
- Lin Li-Te
- Lin Wu-Chou
- Liu Chia-Hao
- Liu Jah-Yao
- Liu Wei-Min
- Lu Chien-Hsing
- Lu Yen-Feng
- Seow Kok-Min
- Sheu Bor-Ching
- Shih Chuan-Chi
- Su Her-Young
- Sun Hsu-Dong
- Sun Lou
- Sun Pi-Lin
- Teng Sen-Wen
- Torng Pao-Ling
- Tsai Chih-Ping
- Tsai Hsiao-Wen
- Tsui Kuan-Hao
- Wang Chin-Jung
- Wang Kuan-Chin
- Wang Peng-Hui
- Wang Po-Hui
- Wang Yeou-Lih
- Wang Yu-Chi
- Wen Kuo-Chang
- Wu Hua-Hsi
- Wu Meng-Hsing
- Wu Wen-Yih
- Yen Men-Luh
- Yen Ming-Shyen
- Yu Hann-Chin
- Yu Mu-Hsien
- Yuan Chiou-Chung
- Publication venue
- , the Chinese Medical Association. Published by Elsevier Taiwan LLC.
- Publication date
- 30/11/2016
- Field of study
AbstractEndometriosis, defined by the presence of viable extrauterine endometrial glands and stroma, can grow or bleed cyclically, and possesses characteristics including a destructive, invasive, and metastatic nature. Since endometriosis may result in pelvic inflammation, adhesion, chronic pain, and infertility, and can progress to biologically malignant tumors, it is a long-term major health issue in women of reproductive age. In this review, we analyze the Taiwan domestic research addressing associations between endometriosis and other diseases. Concerning malignant tumors, we identified four studies on the links between endometriosis and ovarian cancer, one on breast cancer, two on endometrial cancer, one on colorectal cancer, and one on other malignancies, as well as one on associations between endometriosis and irritable bowel syndrome, one on links with migraine headache, three on links with pelvic inflammatory diseases, four on links with infertility, four on links with obesity, four on links with chronic liver disease, four on links with rheumatoid arthritis, four on links with chronic renal disease, five on links with diabetes mellitus, and five on links with cardiovascular diseases (hypertension, hyperlipidemia, etc.). The data available to date support that women with endometriosis might be at risk of some chronic illnesses and certain malignancies, although we consider the evidence for some comorbidities to be of low quality, for example, the association between colon cancer and adenomyosis/endometriosis. We still believe that the risk of comorbidity might be higher in women with endometriosis than that we supposed before. More research is needed to determine whether women with endometriosis are really at risk of these comorbidities
Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries
- Author
- Aamir Faiqa Binte
- Aamir Syed Roohan
- Ababneh Adnan
- Abbal Muhammad Anas
- Abbas Ahmed M
- Abbas Mostafa
- Abd-Albain Montasir A
- Abdalei Abdulwahab
- Abdalla Ahmed
- Abdalla Ahmed Yassir
- Abdalla Mohamed Galal Ali
- Abdalla Zainab
- Abdallah Mohamed M
- Abdalmahmoud Noon Ezzeldien
- Abdalsadeg Rowa
- Abdelaal Ahmed M
- Abdelbagi Alnazeer Y
- Abdelbaky Mostafa
- Abdelbaset Doaa
- AbdElbaset Esraa
- Abdelbast Menhag
- Abdelfatah Mohammed Abdelnasser
- Abdelgawad Samia
- Abdelhamid Mohamed M
- Abdeljaber Mahmoud
- Abdelkhalig Mubarak
- Abdelmaksoud Mohamed
- Abdelmeguid Rana
- Abdelmelek Dhia Errahmane
- Abdelnaeam Samah
- Abdelnasser Mohammad K
- Abdelrahim Najwa
- Abdelrahman Amira
- Abdelrahman Ayman
- Abdelsalam Hebatalla
- Abdelsamed Enas Abdelbaset
- Abdelwahab Khaled
- Abdoun Meriem
- Abdulali Fatima
- Abdulaziz Mohamed
- Abdulla Dheba Almukhtar
- Abdullah Bahiyah
- Abdullah Bahiyah
- Abdullah Walaa
- Abdullahi Habiba Ibrahim
- Abdulrahman Ahmed
- Abdulrasheed Lubabatu
- Abdulwahed Eman
- Abdulwahed Eman
- Abeysirigunawardana Dewmi
- Abidin Muhammad Fihmi Zainal
- Abiola Olukayode
- Abiyere Henry
- Abodina Ahmed Mohammed
- Aboelela Reham
- AboElfarh Hadeer Elsaeed
- Aboudlal Husein
- AbouHiekal Osama
- Aboulfotouh Ahmed
- Abozid Anwaar
- Abubaker Noora
- Abubaker Noora
- Abufanas Asma
- Abughanima Mahmoud
- Abuhashem Shehab
- Abulafia Daniel
- Abushaala Fatima
- Abushanab Khaled
- AbuShawareb Issa
- Abuuqteish Hamza
- Abuzaho Amany
- Achem Arome
- Adam Eithar
- Adam Mohammed
- Adam Mohammed A
- Addalla Mohamed
- Addley Jordan
- Adeleye Gbadebo
- Adeniyi Adebayo
- Adewole Nathaniel
- Adeyemo Olabisi
- Adeyeye Ademola
- Adeyeye Ademola
- Adly Michael
- Adnan Siti Nasyirah Nisya
- Ads Adel Mohamed
- Ads Alaa Mohamed
- Adze Joel Amwe
- Afeikhena Ehis
- Agida Teddy
- Agilla Hamza
- Agnew Emilie
- Agu Joy Onyekachi
- Ahmad Zatul Akmar
- Ahmed Abdalla
- Ahmed Ahmed
- Ahmed Ahmed
- Ahmed Alaaaldeen
- Ahmed Entisar
- Ahmed Habeeba
- Ahmed Hatem
- Ahmed Reem
- Ahmed Rehab
- Ahmed Rihab
- Ahmed Rogia Ahmed Abdalla
- Ahmed Ruaa
- Ahmed Sharwany
- Ahmed Uzair
- Ahmed Wahiba
- Ahmeed Sultan
- Airede Lydia Regina
- Aitchison Lori
- Ajredini Mirac
- Ajulo Adeshina A
- Akaba Godwin
- Akasha Mazin
- Akbar Maha Ghulam
- Akbuz Seyma Orcan
- Akdere Hakan
- Akın Bilge
- Akkaya Ege Nur
- Akpamgbo Chukwunonso Nnamdi
- Akwaisah Ayoub
- Al Hammoud Amr
- Al Rawashdeh Toka
- Al-Baw Mahmoud
- Al-Dahdouh Mosheer
- Al-Haek Safa’
- Al-Hazaimeh Mo'ath
- Al-issawi Dima
- Al-Issawi Subhi
- Al-jammal Maryam
- Al-Juaifari Maytham A
- Al-Mwajeh Tesneem
- Al-Omary Sohaib
- Al-Quossi Mohammed
- Al-Shambaty Yasir Babkir Ali
- Al-Shami Qotadah
- Al-Smirat Heba
- Al-Tahayneh Sief-Addeen
- Al-Touny Aiman
- Al-Touny Shimaa
- Al-zawaydeh Alia
- Alaa Ali
- Alabed Ebtihal
- Alagelli Fatma
- Alagoz Ahmet Can
- Alameen Hind
- Alameen Maram
- Alamlih Laith
- Alaqoubi Retaj
- Alarabi Rehab
- Alariby Fatima
- Alatefi Dawood
- Alathameen Nassar
- Albakosh Bashir Abobaker
- Albanopoulos Konstantinos
- Albarhomy Osama
- Albarki Aisha
- Albashaireh Alaa
- Albatni Safa Sasi
- Albayadi Eslam
- Alboon Mosab
- Alboridy Muneera
- Alboueishi Asraa Ali
- Aldeges Marwan
- Aldreawi Mohammed
- Alflite Asil Omar Saleh
- Alfrijat Tamam
- Alfrjani Tariq
- Algabbasi Salima
- Algatanesh Nassib
- Alhadad Qamrah
- Alhaddad Hoda Salem
- Alhaleem Ayah
- Alhaleeq Saif
- Alharam Abtisam
- Alhashimi Abdulhadi Mohammed Alhadi
- Alhassan Monzer
- Alhudhairy Sara
- Ali Ahmed
- Ali Aml
- Ali Doua
- Ali Eithar M
- Ali Iqra Fatima Munawar
- Ali Maab
- Ali Manal
- Ali Muhammad
- Ali Radwa
- Ali Rawan Alsheikh
- Ali Rzan Ali Hamedelneel
- Ali Shehroz
- Aliosin Oleg
- Aljamal Mohammad
- Aljamal Sarah
- Alkaraja Layth
- Alkaseek Akram
- Alkazali Mustafa
- Alkchr Hayat Ben Hasan Mohamed A A
- Alkhatib Abed Alazeez
- Allam Shereen
- Almahroush Marin
- Almakki Doha Mohammed Ahmed
- Alnajjar Lara
- Alnajjar Majjd
- Alnatsheh Wesam
- Alnour Ammar
- Alomar Rabiaa
- Alomari Yazan
- Alqaarh Aya
- Alragig Zahra
- Alrifae Ghaliya Mohamed H
- Alrosan Risan
- Alsagoff Sharifah Nor Amirah Syed Abdul Latiff
- Alsaid Hamza
- Alsaify Esmat
- Alsaih Sawsan
- Alsari Najah
- Alshareea Entisar
- Alshawadfy Abdelrhman
- Alshawesh Aisha
- Alsheik Ahmad
- Alsori Mohamed
- Alsoudani Ali
- Altabbaa Hashem
- Altahir Mohamed
- Altair Mawadda
- Altaweel Ahmad
- Altughar Bushra
- Alvarez Matias
- Alvarez-Lozada Luis Adrian
- Alvarez-Lozada Luis Adrian
- Alwahaib Anas
- Alwash Mohammed
- Alzarga Ali
- Alzarouq Ebtisam
- Alzarroug Amal
- Alzghoul Bader
- Alzyoud Osama
- Amarasekara Mishka
- Amary Marwa
- Ametov Amet
- Amin Mostafa K
- Aminu Bashiru
- Aminu Muhammad Baffah
- Ammar Ahmed Siddique
- Amro Dana
- Ananthapadmanabhan Shravankrishna
- Anderson Paul
- Andrew Paul Chimezie
- Andriani Adelaide
- Anestiadou Elissavet
- Angelis Fragkiskos
- Angeslis Fragkiskos
- Aqeel Syed Talha Bin
- Aral Canan
- Arebi Jaber
- Arnaoutoglou Eleni
- Arslangilay Mert
- Arvanitaki Alexandra
- Asadyari-Lupo Shadie
- Ashar Nur Ayuni Khirul
- Ashour Amira
- Ashraf Hamza
- Ashur Abir Ben
- Asjad Imran
- Askar Aamal
- Askin Abdullah Emre
- Aslam Muhammad Nadeem
- Aslan Merve
- Aslangilay Mert
- Astal Mohammed
- Asudo Felicia
- Atadag Yildiz Buyukdereli
- Atef Dina
- Athamneh Tayseer
- Athanasiadis Apostolos
- Ather M Hammad
- Atherton Kristy
- Atia Ahmed
- Atici Semra Demirli
- Atilhan Ridvan
- Atim Terkaa
- Atiq Tabish
- Atta Raneem
- Attia Mohamed
- Attiya Omar
- Awad Hasan
- Awadallah Safaa
- Awoyinka Babatunde
- Ayasrah Salem
- Aydin Cemil
- Aydoğdu Erhan Onur
- Ayogu Emeka
- Ayoub Kerillos
- Ayyad Alaa
- Azboy Ibrahim
- Azer Armia
- Azhari Malaz
- Aziz Aliya Begum
- Babalola Olakunle
- Babar Daniyal
- Babekir Enas Mohammedtom Abdulhameed
- Babiker Afra
- Bacariza Loreto
- Baccar Marwen
- Badawy Asmaa
- Badi Hussameddin
- Badr Karim
- Badri Danniel
- Bagazi Doaa
- Bailey Ashley
- Bakare Adewumi
- Bakari Maisaratu A
- Bakeer Hibah Bileid
- Bakeer Mohammed
- Balciscueta Zutoia
- Ballah Shirahn
- Balogh Zsolt
- Baltacı Zeynep Hazal
- Banaga Essam Eldien Abuobaida
- Banerjee Arnab
- Banihani Farah
- Barbara Silvia Jasmine
- Barbaro Antonio
- Bareka Metaxia
- Bariun Yara
- Barka Sharf
- Barker John
- Barker Sally
- Barsoum Fady
- Basam Aya
- Basam Aya
- Bassam Ahmad
- Bassey Asi-oqua
- Bataineh Saad
- Bature Stephen Bodam
- Bayram Cigdem
- Baysallar Duygu
- Baziotis-Kalfas Kristian
- Beatson Nicholas
- Bei Michael
- Bektas Sebnem
- Bell David
- Benamor Oumayma
- Benek Duygu Ece
- Benham Emily
- Benismai Israa
- Bensalem Marya
- Bensalem Serien Hossain
- Benyani Simran Vinod
- Bernabei Massimiliano
- Betts Aisling
- Bezweek Adel
- Bhikha Jainey
- Bindra Randipsingh
- Binnawara Muhannud
- Bird Katie
- Bisgin Tayfun
- Bitsianis Stefanos
- Blake Jessica
- Bland Laura
- Blassey Aneel
- Blundell Jian
- Bobba Sriya
- Bockxmeer John Van
- Bolam Scott Matthew
- Bolton Damien
- Bosi Simone
- Bouaoud Souad
- Bouchenak Kamel
- Boussahel Ikram Fatima Zohra
- Bowman Sarah
- Boyd Theresa
- Boyes Hamish
- Boyley Jessica
- Bozhko Maxim
- Bozkir Haktan Ovul
- Bozkurt Mehmet Abdussamet
- Bresadola Vittorio
- Brewster Dani
- Brooke Kenya
- Brown Georgia
- Brown Matthew
- Buari Taiwo
- Buhavac Milos
- Bunjo Zachary
- Burrows Emalee
- Burruso Luca
- Busaidi Ibrahim S Al
- Bushaala Hassan
- Butterworth Yasmine
- Butyrskii Aleksandr
- Cabalag Carlos
- Cade Richard
- Cakcak Ibrahim Ethem
- Cakir Niyazi
- Calini Giacomo
- Calini Giacomo
- Camkıran Elifsu
- Canavese Anna
- Candan Mert
- Canny Mitch
- Canton Joshua
- Capar Mehmet Ali
- Cardelli Stefano
- Carlos Angela
- Carnuccio Emma
- Carre Xenia
- Casciola Francesca
- Castagnini Francesco
- Catalioto Caterina
- Cepe Hale
- Cerinic Pietro Matucci
- Certel Alperen Taha
- Cetınkaya Zeynep Sahan
- Chakroun Sawssen
- Chambers Jessica
- Champipis Apostolos
- Chan Alex
- Chan Ashley
- Chan Juliet
- Chan Justin
- Chan Nicholas
- Chand Namisha
- Chandiok Karan
- Chandler Callum
- Chandra Pooja
- Chang Jared
- Chang Kelvin
- Changati Varun
- Chao Phoebe
- Chau Michelle
- Chau Michelle
- Chauhan Karanjeet
- Chawla Tabish
- Chen Andrew
- Chen Brian
- Chen Paul
- Chen Yan
- Chene Danielle
- Cheng Felicity
- Cheng Felicity
- Cheung Aiden
- Cheung King Tung
- Chiappe Caterina
- Chidambaram Seevakan
- Chilaka Lalitya
- Chlebicka Tara
- Choi Colin Chan-Min
- Choi Horim
- Choong Zhi Shyuan
- Chou Justin
- Chowdhury Nebula
- Chowdhury Sharfuddin
- Chua Alan
- Chua Alyssa
- Chua Anne Qi
- Chua Matthew
- Chye David
- Cianci Pasquale
- Ciranni Dominico
- Clair Sophie St
- Clanfield Matthew
- Clarnette Nick
- Clemente-Navarro Pablo
- Cobden Andrew
- Colaco Ashley
- Collins A-J
- Collins Josh
- Conlon Niamh
- Conversano Ivana
- Cook Holly
- Coomber Grace
- Copertino Nicolas
- Cordingley Timothy
- Cornwell Charlotte
- Cornwell Charlotte
- Corrigan Angela
- Cover Jacinta
- Craig-Lucas Alayna
- Crossman Mason
- Crostella
- Crotty Anna
- Cuneo Beatriz
- Currie William
- Cuthbert Mitchell
- Cyr Kathryn
- Çolak Eli ̇f
- Dabas Ayman Arhuma
- Dagklis Themistoklis
- Dagsali Alara Ece
- Dahshan Shaimaa
- Dajti Gerti
- Dang Jennifer
- Das Ankita
- Das Ankita
- Daud Mohamed Ashraf Mohamed
- Daudu Davina
- Davies Lily
- Dawod Nimatee
- Dawood Ali
- Dawson Abby
- Dawson Amanda
- Dawson Amanda
- Deafallah Asmaa
- Demirkiran Mehmet Ali
- Denby Hannah
- Dennaoui Rami
- Derwish Khawla
- Dharmaratne Isini
- Diab Menna
- Dimofte Mihail Gabriel
- Dindar Arzu
- Ding George
- Divekar Tanya
- Divinagracia Janelle
- Dogan Tugce
- Domenech Julio
- Donaldson Olivia
- Dong Isabella
- Dong Jason
- Donia Mohamed
- Dorovinis Panagiotis
- Douglas Rebecca Indiana
- Doulami Georgia
- Dowdle Benjamin
- Duart Mireia
- Dudi-Venkata Nagendra
- Duffield Jaime
- Durdu Beyza
- Durmus Elif
- Düzyol Zeynep
- Dzator Stephen
- Ebrahim Alshymaa
- Edwards Elton
- Edwards Liam
- Edwards Liam
- Egerton James
- Egzait Raneem
- Eid Ahmed
- Eismontas Vitalijus
- Ejaz Adya
- Ejembi Peter
- Ekwebelam Jennifer
- El-Masry Mariam
- el-mola Amira Gad
- El-Sakka Ahmed
- El-Taher Ahmed Kamal
- Elaagib Amna
- Eldaim Khalid Nour
- Eldarat Tarik Ahmed
- Eldomiaty Donia
- Elessi Khamis
- Elewa Ahmed
- Elfadli Mustafa
- Elfallah Sara
- Elfeki Hossam
- Elferis Donia
- Elgadi Tahani
- Elghamry Ahmed
- Elgharib Asmaa Moatasem
- Elghazy Mohamed Abdelaziz
- Elgherwi Laila
- Elghoul Youssef
- Elgindy Yara
- Elhadi Muhammed
- Elhadi Muhammed
- Elhadi Muhammed
- Elhadi Rawan Elnoman Hamadelniel
- Elhassan Baraa
- Elia Michael
- Elieyioğlu Güşta
- Elizabeth
- Elkenawi Karim
- Elkharaz Omar A
- Elkheshebi Ahlam
- Elkhodary Ahmed
- Ellepola Hasthika
- Ellilly Ahmed
- Elmaghrabey Abdallah
- Elmehdawi Haitham
- Elmubark Abdelhadi
- Elnagar Rahma
- Elporgay Aya
- Elreaid Fadwa
- Elreaid Fatma Fathi
- Elrishi Fatheia
- Elsaied Mostafa
- Elsawy Amr
- Eltaib Ibrahim
- Eltayeb Mohammed Omer Mohammed
- Elyan Basel
- Elzoubia Joma
- Emad Humam
- Emam Asmaa
- Emhimmed David
- Enaami Husam
- English Tessa
- Eniola Bolarinwa
- Erginoz Ergin
- Esaiti Salma
- Esho Adriana
- Evans Natalie
- Ezeoke Grace
- Fabbri Nicolò
- fadalah Bader Abo
- Fadlalmola Hammad
- Faisal Arwa
- Fang Carol
- Farag Abdelrahman
- Fares Gamal Elsayed
- Faris Farah
- Fariyike Bunmi
- Farre Joan
- Farrell Michael
- Farrell Michael
- Fasiku Olushola
- Fatima Aleeza
- Fearnley-Fitzgerald Chekodi
- Febre Jorge
- Feierdaiweisi Xireaili
- Feo Carlo V
- Fergar Cem
- Ferguson Liam
- Ferguson Neil
- Fernando Isuru
- Figgitt Ethan
- Filikus Abraham L
- Flame Aki
- Fletcher Joseph
- Flintoft Sean
- Flores-González Ana Karina
- Fong Bryan
- Fong Hakim
- Fong Pei Jun
- Foo Jonathon
- Forbes Clara
- Forsythe Jack
- Fotheringham Penelope
- Fouda Mohamed Fayez
- Fradelos Evangelos
- Franks Angus
- Fraser Calvin
- Frost Taylor
- Fu Jeff
- Fu Yangzirui
- Fuentes Stephie Oyervides
- Fufore Mohammed Bello
- Fujihara Asuka
- Fung James
- Furey Joseph
- Gaafar Mohammed
- Gaarour Osama Samir
- Gaborit Lorane
- Gaborit Lorane
- Gahwagi Milad
- Galal Adham
- Galal-Eldin Sami
- Gallert Kayla
- Gamage Tharushi
- Gan Christine
- Gan Kathy
- Gan Siang Wei
- Gara Mouna
- Garba Mohammad Albuhari
- Garcia Sara
- García Patricia Ludivina González
- Garton Briar
- Garza Alejandro Quiroga
- Garza Francisco Javier Arrambide
- Gattesco Davide
- Gattulli Domenico
- Gebeh Alpha
- Gecici Mehmet Emre
- Gemici Aylin
- Geng Ruxi
- Gentle Juliette
- George Akhita
- George Ria
- Gera Sahil
- Gernhoefer Erin
- Ghaly Moheb
- Ghandi Kushan
- Ghanem Sohila
- Ghemmied Malak
- Ghmagh Rawia
- Ghmagh Reem
- Giannakopoulos Konstantinos S
- Gidiem Doaa
- Gill Sonia
- Gilmore Paul
- Gineeb Hana Yousef
- Giurgius Mary
- Giuzzardi Giulia
- Glyn Tamara
- Glynatsis John
- Glynatsis John
- Goddard Kim
- Goh Sarah
- Goh Sarah
- Goh Sarah
- Gojnich Amy
- Golani Shalni
- Goldfinch Elisabeth
- Goldsmith Oliver
- Golja Damian
- Goonawardena Janindu
- Gopal Hemashree
- Gorgone Mara
- Gould Madeline
- Gover Tolga
- Grada Maren
- Grandi Alyssia De
- Graziadei Vivien
- Green Jemma
- Greenwood Emily
- Greig Hannah
- Grillea Giorgia
- Groot Julia De
- Gross Hannah
- Guerra Ethel Valeria Orta
- Guerra-Juárez Yesika Alejandra
- Guizzardi Giulia
- Gunasekara Aashrinee De Silva Abeweera
- Gundara Justin
- Guner Ali
- Gunn Emma
- Guo Oscar
- Gündoğdu Adnan
- Gweder Rima
- Gyftopoulos Argyrios
- Hadi Arwa
- Hadi Arwa
- Haege Emma
- Haggag Zeyad
- Hakak Fatima
- Halawa Mohamed
- Hamad Huda
- Hamdy Ahmed
- Hamdy Omar
- Hamer Peter
- Hamid Hytham K S
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- Zakaria Mohd Zaim
- Zalloum Jihad
- Zamanbandhon Bushra
- Zambon Mattia
- Zapsalis Konstantinos
- Zargar Kamran
- Zarzour Mohamed A
- Zeng Raymond
- Zeng Raymond
- Zengin Kagan
- Zertuche Juventino Tadeo Guerrero
- Zhang Caitlin
- Zhang Edward
- Zhang Shane
- Zhang Yichi
- Zhao Hailin
- Zheng Helen
- Zhou Karen
- Zhou Yida
- Ziergiebel Felix
- Zou Peishan
- Zuylekom Kate Van
- Zuylekom Katie Van
- Zwain Yasir Adnan
- Zyul'korneeva Sof'ya
- Aladna Abdallah
- Aljoumaa Abdullah
- Nawfal Hamdi
- Niazi Ammar
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P < 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
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- Abdel-Aziz AK
- Abdelfatah S
- Abdellatif M
- Abdoli A
- Abel S
- Abeliovich H
- Abildgaard MH
- Abudu YP
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- Adamopoulos IE
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- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
- Author
- A. -G. Wu
- A. C. Ma
- A. K. Au
- Abdel-Aziz A. K.
- Abdelfatah S.
- Abdellatif M.
- Abdoli A.
- Abel S.
- Abeliovich H.
- Abildgaard M. H.
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- Adamopoulos I. E.
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- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
- Author
- Abbas Rezaianzadeh
- Abdonas Tamosiunas
- Abdul Basit
- Abdul Hamid Zargar
- Abdullah Alkandari
- Abdullatif Husseini
- Abhijit Sen
- Abla M Sibai
- Abu Am Hanif
- Adela Chirita-Emandi
- Adelheid Weber
- Adetoyeje Y Oyeyemi
- Adewale L Oyeyemi
- Adolfo Rubinstein
- Adoubi Kassi Anicet
- Adroaldo Cesar Araujo Gaya
- Afshin Ostovar
- Agnes L Kadvan
- Agneta Sjöberg
- Agneta Yngve
- Agnès Le Port
- Agustinus Soemantri
- Agustín Perez-Londoño
- Ahmad A Zainuddin
- Ahmad Faudzi Yusoff
- Ahmad Reza Dorosty
- Ahmed A Madar
- Aida Pilav
- Aïcha Soumaré
- Akaninyene Otu
- Akihiro Yoshihara
- Akkumis Salhanova
- Akram Pourshams
- Ala'a Alkerwi
- Alain Morejon
- Alanna G da Silva
- Albertino Damasceno
- Alberto Barceló
- Alberto Palloni
- Albina A Fakhretdinova
- Alejandro Diaz
- Aleksander Giwercman
- Aleksandra Gomula
- Aleksandra Piwonska
- Alessandro Gialluisi
- Aletta E Schutte
- Alexander D Deev
- Alexandra M Cucu
- Alexandre C Pereira
- Alfonso Siani
- Alfonso Sousa-Poza
- Ali Ahmadi
- Ali Akbar Shayesteh
- Ali Esmaeili
- Ali Ghanbari
- Ali Reza Safarpour
- Alice Bonilla-Vargas
- Alicia Matijasevich
- Alina G Platonova
- Alina Kerimkulova
- Aline Meirhaeghe
- Aline P Batista
- Alireza Ansari-Moghaddam
- Alireza Khosravi
- Alireza Moslem
- Alireza Sadjadi
- Alisha N Wade
- Alison J Hayes
- Alison J Price
- Allan G Hill
- Allan Linneberg
- Almaz Sharman
- Altan Onat
- Aluisio Jd Barros
- Alun Evans
- Amalia De Curtis
- Amanda G Thrift
- Amanda J Cross
- Amaneh Shayanrad
- Ambady Ramachandran
- Amelia C Crampin
- Amina Barkat
- Amir Houshang Mehrparvar
- Amirabbas Momenan
- Ana Azevedo
- Ana B Crujeiras
- Ana Barradas-Pires
- Ana Carolina Mgn de Sá
- Ana D González-Alvarez
- Ana Henriques
- Ana I Rito
- Ana Jelaković
- Ana Maria B Menezes
- Ana P Ortiz
- Ana Paula C Cândido
- Anabela Mota-Pinto
- Anar Dushpanova
- Anastasia Markaki
- Anders Grøntved
- Andre L Guimaraes
- Andre P Kengne
- Andrea Gazzinelli
- Andrea Gualtieri
- Andrea Rodriguez-Martinez
- Andrea Rvr Horimoto
- Andrea Schneider
- Andrea Y Rodríguez
- Andrea Zentai
- Andreas Stang
- Andreia N Pizarro
- Andrew Kingston
- Andrew Reynolds
- Andrew Wong
- Andrzej Galbarczyk
- Andrzej Pająk
- Andrzej Więcek
- Anelise Reis Gaya
- Aneta Grajda
- Aneta Weres
- Anette Varbo
- Angel R Gonzalez
- Angela Chetrit
- Angela Döring
- Angela Spinelli
- Angelika Schaffrath Rosario
- Angelique Chan
- Angélica M Ochoa-Avilés
- Anie Marcil
- Anil Poudyal
- Anja L Madsen
- Anja Schienkiewitz
- Anna Bartosiewicz
- Anna Bugge
- Anna Fijalkowska
- Anna Jansson
- Anna V Alieva
- Annamari Lundqvist
- Anne A Bjerregaard
- Anne Chinnock
- Anne Juolevi
- Anne Taylor
- Anne Tjonneland
- Anneke Blokstra
- Annette J Dobson
- Annette Peters
- Annika Rosengren
- Anthony Kafatos
- Antonia Trichopoulou
- Antonio Bernabe-Ortiz
- Antonio Cabrera de León
- Antonio M Silva
- Antonio Mistretta
- Antonio Pedro Graça
- Antonio Prista
- Antonis Zampelas
- Antonisamy Belavendra
- Anu Mishra
- Anwar M Batieha
- Archie W Rayner
- Areti Triantafyllou
- Argyro Karakosta
- Ari Voutilainen
- Aristides M Machado-Rodrigues
- Arnaud Chiolero
- Aroor Bhagyalaxmi
- Arsalan Khaledifar
- Artur Mazur
- Arvind Pandey
- Arwa M Alshangiti
- Aryeh D Stein
- Asher Fawwad
- Attilio Rigotti
- Atul Trivedi
- Augustin F Beybey
- Augustine N Odili
- Augusto Di Castelnuovo
- Aung Soe Htet
- Ausra Petrauskiene
- Avula Laxmaiah
- Axel C Carlsson
- Aya Mostafa
- Ayman A Zayed
- Azaliia M Tuliakova
- Azhar Dyussupova
- Azim Nejatizadeh
- Azli Baharudin
- Åsa Ågren
- Badreya Al-Lahou
- Bagher Larijani
- Bahareh Kheiri
- Bahman Cheraghian
- Bakary Jallow
- Baltazar Nunes
- Barbara Heude
- Barbara Thorand
- Barry M Popkin
- Batyrbek Assembekov
- Beatriz D Schaan
- Bee Koon Poh
- Behrooz Hamzeh
- Bekbolat Zholdin
- Belgin Unal
- Belong Cho
- Ben Schöttker
- Benjamin Acosta-Cazares
- Benoit Salanave
- Benson M Kazembe
- Bente Sparboe-Nilsen
- Bernard Maire
- Bernardo L Horta
- Bernhard O Boehm
- Bert-Jan van den Born
- Bettina Bringolf-Isler
- Bharathi Viswanathan
- Bhawesh Koirala
- Bihungum Bista
- Bill Stavreski
- Bin Zhou
- Bing Zhang
- Birgit Linkohr
- Biruta Velika
- Blanca Sandra Ruiz-Betancourt
- Bo Werner
- Boban Mugoša
- Bogdan Wojtyniak
- Bojan Jelaković
- Bontha V Babu
- Boyd A Swinburn
- Börge Schmidt
- Branimir Leskošek
- Breige A McNulty
- Brian Oldenburg
- Brooklyn Fraser
- Bruna Gonçalves Cordeiro da Silva
- Buthaina M Alkhatib
- Børge G Nordestgaard
- Caleb Ochimana
- Calogero Saieva
- Calvin Ke
- Camilla T Damsgaard
- Carl Lachat
- Carla Menêses Hardman
- Carlo Maria Barbagallo
- Carlos A Aguilar-Salinas
- Carlos O Mendivil
- Carlos P Boissonnet
- Carmen Iñiguez
- Carolina B Tarqui-Mamani
- Caroline H Fall
- Caroline Ramos de Moura Silva
- Carsten O Schmidt
- Cassiano Ricardo Rech
- Catherine Kyobutungi
- Catterina Ferreccio
- Cecilia Björkelund
- Cecily Kelleher
- Cesar G Victora
- Cézane P Reuter
- Chandini Nekkantti
- Chao Qiang Jiang
- Charalambos A Hadjigeorgiou
- Charles Agyemang
- Charles K Mondo
- Charles Lunogelo
- Charles Sossa Jérome
- Charlie Lim
- Charlotte B Ottendahl
- Charmaine A Duante
- Charumathi Sabanayagam
- Chiara Donfrancesco
- Chien-An Sun
- Chien-Jen Chen
- Ching-Yu Cheng
- Chinh Nguyen Huu
- Chinwuba Ijoma
- Chongjian Wang
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- Christa Meisinger
- Christian Gieger
- Christina C Dahm
- Christina Howitt
- Christina Mavrogianni
- Christine Cameron
- Christophe Tzourio
- Christopher J Paciorek
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- Cihangir Erem
- Claes Ohlsson
- Clara Homs
- Claudia M Hormiga
- Cláudia S Minderico
- Clicerio González-Villalpando
- Clive Osmond
- Coimbatore Subramaniam Shanthirani
- Con Burns
- Constance Schultsz
- Constanta Huidumac Petrescu
- Cora L Craig
- Correia Júnior Marco Aurélio de Valois
- Cosmin R Cojocaru
- Cristina P Padez
- Crizian G Saar
- Cynthia M Pérez
- Cyrus Cooper
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- Damaskini Valvi
- Damian K Francis
- Dan Zhu
- Daniel Bia
- Daniel Fernández-Bergés
- Daniel Ferrante
- Daniel G Vasques
- Daniel Lemogoum
- Daniel Weghuber
- Daniela Galeone
- Daniela Kállayová
- Daniela Pierannunzio
- Daniela Rodrigues
- Daphne Lai
- Daphne Mirkopoulou
- David A Gonzalez-Chica
- David De Ridder
- David Faeh
- David Goltzman
- Davide Noto
- Davood Khalili
- Deborah C Malta
- Debra S Judge
- Deena Al Asfoor
- Deepak N Amarapurkar
- Delphine De Smedt
- Demetre Labadarios
- Denise Eldemire-Shearer
- Dermot O'Reilly
- Dénes Molnár
- Diana A Santos
- Diane T Meto
- Dianna J Magliano
- Dickman Gareta
- Diego Augusto Santos Silva
- Diego G Christofaro
- Diego Salmerón
- Diego Vanuzzo
- Dimitrios Papandreou
- Dimitrios Poulimeneas
- Dimitrios Trichopoulos
- Dirk De Bacquer
- Dirk Vanderschueren
- Dominique Cottel
- Dominique Hange
- Dong Zhao
- Dongfeng Gu
- Dora Romaguera
- Doris Stöckl
- Dorja Vocanec
- Doroteia A Höfelmann
- Dusko J Bjelica
- Dušan Grafnetter
- Duygu Islek
- Dwi Hapsari Tjandrarini
- E Shyong Tai
- Ebrahim Eftekhar
- Ebrahim Ghaderi
- Eduardo Capuano
- Eduardo Salazar Martinez
- Edward F Fottrell
- Edward Janus
- Edward W Gregg
- Edwige Landais
- Edyta Łuszczki
- Eero O Kajantie
- Efthymios Kapantais
- Eha Nurk
- Ei Ei K Nang
- Eiji Oda
- Ekaterina Chikova-Iscener
- Ekaterina Stoyanova
- Elaine Dennison
- Elaine M Murtagh
- Eldridge Ferrer
- Elena Anufrieva
- Elena Bogova
- Elena Pahomova
- Elena Sacchini
- Elena V Skoblina
- Eleonora d'Orsi
- Elias F Gudmundsson
- Elin Kolle
- Elin P Sørgjerd
- Elio Riboli
- Elisabete Ramos
- Elisabetta L Romeo
- Eliza Cinteza
- Eliza Markidou Ioannidou
- Ellina M Iakupova
- Elling Bere
- Ellis Owusu-Dabo
- Ellisiv B Mathiesen
- Elnaz Faramarzi
- Els Clays
- Else Karin Grøholt
- Elvis Oa Wambiya
- Elvynna Leong
- Elysée Claude Bika Lele
- Elzbieta Dziankowska-Zaborszczyk
- Eman Aly
- Emanuel Zitt
- Emanuela Gualdi-Russo
- Emanuela Pettenuzzo
- Emiel Hoogendijk
- Emily B Wong
- Emily Sonestedt
- Emma Ruiz Moreno
- Emmanuel Cohen
- Emmanuella Magriplis
- Eng Joo Tan
- Enguerran Macia
- Enisa Kujundzic
- Enrique Gutiérrez González
- Enzo Manzato
- Erfan Ghasemi
- Eric Monterrubio-Flores
- Erik J Timmermans
- Erik Lykke Mortensen
- Erkin Mirrakhimov
- Ertugrul Celikcan
- Eruke E Egbagbe
- Espen Bjertness
- Esteban Carmuega
- Esther Lopez-Garcia
- Esther M González-Gil
- Ethel Santacruz
- Eugène Sobngwi
- Eunice Ugel
- Eva Corpeleijn
- Eva Gerdts
- Eva Karaglani
- Eva Martos
- Evangelia Tzala
- Ewelina Czenczek-Lewandowska
- Éva Kovács
- Fabian Rohner
- Fabián Méndez
- Fabio Galvano
- Fadi J Charchar
- Fadia AlBuhairan
- Fangfang Chen
- Farahnaz Joukar
- Farhad Moradpour
- Farhad Pourfarzi
- Farhad Zamani
- Fariborz Mansour-Ghanaei
- Farid Najafi
- Farshad Farzadfar
- Farzad Hadaegh
- Fatai A Maruf
- Fatemeh Malekzadeh
- Fatima Zahra Laamiri
- Felicia Cañete
- Felipe F Casanueva
- Felipe V Cureau
- Felix Gutzwiller
- Felix K Assah
- Felix O Kaducu
- Felix P Phiri
- Fereidoun Azizi
- Fernanda Cunha Soares
- Fernando Rigo
- Fernando Rodríguez-Artalejo
- Félicité Tchibindat
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- Sadaf G Sepanlou
- Saeed Dastgiri
- Saeed M Omar
- Saeid Eslami
- Saeid Safiri
- Safiah Md Yusof
- Sahar Saeedi Moghaddam
- Sai Yin Ho
- Sajid Soofi
- Salar Rahimikazerooni
- Salim Berkinbayev
- Salim Mohanna
- Salvador Villalpando
- Sameer Narake
- Samuel C Dumith
- San-Lin You
- Sanda M Kolo
- Sandjaja
- Sandra C Fuchs
- Sandra Colorado-Yohar
- Sania Nishtar
- Sanja Musić Milanović
- Sanja Šalaj
- Sanjay Rampal
- Sanjib K Sharma
- Santiago F Gómez
- Santosh K Bhargava
- Sara Magnacca
- Sara Schramm
- Sarah Cuschieri
- Sarah P Garnett
- Sare Safi
- Sareh Eghtesad
- Sari Hantunen
- Saskia Te Velde
- Satoko Sakata
- Sauli Herrala
- Savvas Savva
- Scott B McLean
- Semánová Csilla
- Senthil K Vasan
- Seongjun Ha
- Seppo Koskinen
- Sergej M Ostojic
- Sergio Viana Peixoto
- Seth Adu-Afarwuah
- Seyed Mohammad Hashemi-Shahri
- Seyed Morteza Shamshirgaran
- Seyed Rasoul Zakavi
- Seyed-Ali Mostafavi
- Seyyed-Hadi Ghamari
- Shahla AlDhukair
- Shaker A Alomary
- Shariq R Masoodi
- Sheena E Ramsay
- Sheikh Mohammed Shariful Islam
- Shelly R McFarlane
- Sherali Rakhmatulloev
- Sherilynn Madraisau
- Shina Avi
- Shiqi Zhen
- Shirin Djalalinia
- Shoaib Afzal
- Shoichiro Tsugane
- Shouling Wu
- Shu-Ti Chiou
- Shubash Ganapathy
- Shufa Du
- Shukri F Mohamed
- Shuohua Chen
- Shynar Abdrakhmanova
- Sibel Gogen
- Sigmund A Anderssen
- Silje Steinsbekk
- Silvana P Donoso
- Silvia Bel-Serrat
- Silvije Vuletić
- Simo Pone Larissa
- Simona Bo
- Simona Costanzo
- Simona Giampaoli
- Sinead Brophy
- Sirkka Keinänen-Kiukaanniemi
- Slavica Sovic
- Slawomir Koziel
- Snehalatha Chamukuttan
- Sofia K Malyutina
- Soheir H Ahmed
- Sok King Ong
- Solie Puhakka
- Son Thai Pham
- Songhomitra Panda-Jonas
- Sonya V Galcheva
- Soon-Woo Park
- Sophia J Kiechl
- Sophie Visvikis-Siest
- Sounnia Mediene Benchekor
- Sousana K Papadopoulou
- Srinivasan Kannan
- Stefaan De Henauw
- Stefaan Demarest
- Stefan Adela Gabriela
- Stefan Kiechl
- Stefan Rach
- Stefan Savin
- Stefan Söderberg
- Stefania Maggi
- Stefania Toselli
- Stefano Marventano
- Steinar Krokstad
- Stephen T McGarvey
- Steve Botomba
- Stevo R Popovic
- Stig E Bojesen
- Stine Schramm
- Sudha Ramachandra Rao
- Sudhir Kowlessur
- Suhad Bahijri
- Suhaila Abdul Ghaffar
- Sumit Bharadwaj
- Suntara Klanarong
- Susana C Confortin
- Susana Sans
- Susana Vale
- Susanne Kobel
- Susanne R de Rooij
- Susi Kriemler
- Suyeon Park
- Suzanne C Ho
- Suzanne N Morin
- Svetlana Shalnova
- Sylvain Sebert
- Sylvia Alexius
- Tabara Yasuharu
- Tahir Aris
- Tai Hing Lam
- Tajana Zeljkovic Vrkic
- Takafumi Ishida
- Take Naseri
- Takuro Furusawa
- Tal Shimony
- Tamara R Santos
- Tamás Csányi
- Tamerlan Rajabov
- Tandi E Matsha
- Tania Lopez
- Tania Tello
- Tanja Gm Vrijkotte
- Tara C Coppinger
- Taru Manyanga
- Tasanee Braithwaite
- Tatjana Hejgaard
- Tatyana Slazhnyova
- Tazeen Jafar
- Terence Dwyer
- Terence W O'Neill
- Teresa Haugsgjerd
- Teresa Shamah-Levy
- Terho Lehtimäki
- Thamara Hubler Figueiró
- Thein Thein Htay
- Themistoklis Tzotzas
- Theodora Benedek
- Thet Thet Mu
- Thi Tuyet-Hanh Tran
- Thirunavukkarasu Sathish
- Thomas Ferrao
- Thomas M Dantoft
- Thomas Münzel
- Thomas Waldhör
- Thor Aspelund
- Thorkild Ia Sørensen
- Tien Yin Wong
- Tiffany K Gill
- Tiina Laatikainen
- Tiina Lankila
- Tiina Vlasoff
- Tilema Cama
- Till Ittermann
- Timothy Key
- Tina Harmer Lassen
- Tint Swe Latt
- Tobias F Rinke de Wit
- Tom Wilsgaard
- Tomas Vega
- Tomasz Zdrojewski
- Tomi-Pekka Tuomainen
- Toomas Veidebaum
- Torben Jørgensen
- Toshiharu Ninomiya
- Tran Quoc Bao
- Trevor S Ferguson
- Tuija Jääskeläinen
- Tuyen D Le
- Tze Pin Ng
- Ulf Ekelund
- Ulf Risérus
- Ulla Roggenbuck
- Ulrich Keil
- Ulrike Gehring
- Unjali P Gujral
- Urho M Kujala
- Ursula Kiechl-Kohlendorfer
- Uruwan Yamborisut
- Vaitheeswaran Kulothungan
- Valentina Peterkova
- Valéria Regecová
- Valérie Deschamps
- Valirie N Agbor
- Valter Barbosa Filho
- Vanessa Rouzier
- Vanina Bongard
- Vasiliki Efthymiou
- Vassilis Zafiropulos
- Vayia Rarra
- Vedrana Sember
- Veikko Salomaa
- Vera Lanska
- Vera Musil
- Veronica Mocanu
- Vesna Juresa
- Vesselka L Duleva
- Victor M Herrera
- Victor Matsudo
- Victor Pf Lhoste
- Victoria E Soto-Rojas
- Victoria Farrugia Sant'Angelo
- Vijaya Lingam
- Viktoria Anna Kovacs
- Viktoriya Furdela
- Vilma E Irazola
- Vilma Kriaucioniene
- Vilmundur Gudnason
- Vilnis Dzerve
- Vinay B Nangia
- Vincent Jr DeGennaro
- Vincenzo Capuano
- Vincenzo Solfrizzi
- Violeta Iotova
- Virginija Dulskiene
- Virgílio V Ramires
- Visnja Djordjic
- Viswanathan Mohan
- Viviana Guajardo
- Viviane C Cardoso
- Vladimir Kutsenko
- Wafaie W Fawzi
- Wan Mohamad Wan Bebakar
- Wan Nazaimoon Wan Mohamud
- Wei Zheng
- Wei-Cheng Lo
- Wei-Yen Lim
- Weili Yan
- Wen-Harn Pan
- Wenbin Wei
- Wendy Van Lippevelde
- Wenhua Zhao
- Wichai Aekplakorn
- Willem A Hanekom
- William A Neal
- William R Tebar
- Wilma M Hopman
- Winsome R Parnell
- Wm Monique Verschuren
- Wojciech Drygas
- Wojciech Rusek
- Wolfgang Ahrens
- Wolfgang Kratzer
- Xenophon Theodoridis
- Xiangjun Wang
- Xiaoguang Yang
- Xiaotian Liu
- Ximena Berrios Carrasola
- Xinyi Gwee
- Xiu-Hua Guo
- Xu Lin
- Xu Ma
- Xueling Sim
- Xun Tang
- Ya Xing Wang
- Yadlapalli S Kusuma
- Yajaira Briceño
- Yang Yang
- Yanhui Dong
- Yanina Zocalo
- Yanitsa V Zhecheva
- Yannis Manios
- Yanping Li
- Yemane Berhane
- Yeunsook Rho
- Yeva Movsesyan
- Yi Song
- Yi Zeng
- Yih Chung Tham
- Yiling J Cheng
- Yin Guo
- Ying-Wei Wang
- Yingfeng Zheng
- Yn-Tz Sung
- Yong Tao
- Yonghua Hu
- Yosef Farzi
- Yoto Yotov
- Youcef Laid
- Young-Ho Khang
- Yousef Saleh Khader
- Yu-Ling Yu
- Yuan He
- Yufang Bi
- Yuki Fujita
- Yulia Balanova
- Yuliya V Solovieva
- Yuna He
- Yunjiang Yu
- Yury P Nikitin
- Yves Kameli
- Yves Martin-Prevel
- Yvonne T van der Schouw
- Zahra Mohammadi
- Zbigniew Gaciong
- Zbigniew Kulaga
- Zengchang Pang
- Zhamilya Battakova
- Zhamyila Usupova
- Zhanna Kalmatayeva
- Zhen-Yu Zhang
- Zhengming Chen
- Ziad A Abdeen
- Zivka Dika
- Zlatko Fras
- Zulfiqar A Bhutta
- Zulfiya Abdurrahmonova
- Zumin Shi
- Łukasz Kryst
- Publication venue
- Publication date
- 01/03/2024
- Field of study
Background Underweight and obesity are associated with adverse health outcomes throughout the life course. We
estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from
1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories.
Methods We used data from 3663 population-based studies with 222 million participants that measured height and
weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate
trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children
and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the
individual and combined prevalence of underweight (BMI <18·5 kg/m2) and obesity (BMI ≥30 kg/m2). For schoolaged children and adolescents, we report thinness (BMI <2 SD below the median of the WHO growth reference)
and obesity (BMI >2 SD above the median).
Findings From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in
11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed
changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and
140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of
underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and
countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior
probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse
was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of
thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a
posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%)
with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and
obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for
both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such
as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged
children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls
in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and
42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents,
the increases in double burden were driven by increases in obesity, and decreases in double burden by declining
underweight or thinness.
Interpretation The combined burden of underweight and obesity has increased in most countries, driven by an
increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy
nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of
underweight while curbing and reversing the increase in obesit
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants.
- Author
- Abarca-Gomez Leandra
- Abdeen Ziad A.
- Abu-Rmeileh Niveen M.
- Acosta-Cazares Benjamin
- Adams Robert J.
- Aekplakorn Wichai
- Afsana Kaosar
- Afzal Shoaib
- Agdeppa Imelda A.
- Aghazadeh-Attari Javad
- Aguilar-Salinas Carlos A.
- Agyemang Charles
- Ahmad Noor Ani
- Ahmadi Ali
- Ahmadi Naser
- Ahmadi Nastaran
- Ahmadizar Fariba
- Ahmed Soheir H.
- Ahrens Wolfgang
- Ajlouni Kamel
- Al Nsour Mohannad
- Al-Raddadi Rajaa
- Alarouj Monira
- AlBuhairan Fadia
- AlDhukair Shahla
- Ali Mohamed M.
- Alkandari Abdullah
- Alkerwi Ala'a
- Allin Kristine
- Aly Eman
- Amarapurkar Deepak N.
- Amougou Norbert
- Amouyel Philippe
- Andersen Lars Bo
- Anderssen Sigmund A.
- Andre Moura-dos-Santos Marcos
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Ansong Daniel
- Aounallah-Skhiri Hajer
- Araujo Joana
- Ariansen Inger
- Aris Tahir
- Arku Raphael E.
- Arlappa Nimmathota
- Aryal Krishna K.
- Aspelund Thor
- Assah Felix K.
- Assuncao Maria Cecilia F.
- Auvinen Juha
- Avdicova Maria
- Azevedo Ana
- Azimi-Nezhad Mohsen
- Azizi Fereidoun
- Azmin Mehrdad
- Babu Bontha V.
- Bahijri Suhad
- Balakrishna Nagalla
- Balanova Yulia
- Balanova Yulia
- Bamoshmoosh Mohamed
- Banach Maciej
- Banadinovic Maja
- Bandosz Piotr
- Banegas Jose R.
- Baran Joanna
- Barbagallo Carlo M.
- Barcelo Alberto
- Barkat Amina
- Barreto Marta
- Barros Aluisio J. D.
- Bartosiewicz Anna
- Basit Abdul
- Bastos Joao Luiz D.
- Bata Iqbal
- Batieha Anwar M.
- Batyrbek Assembekov
- Baur Louise A.
- Beaglehole Robert
- Bebakar Wan Mohamad Wan
- Belavendra Antonisamy
- Ben Romdhane Habiba
- Benchekor Sounnia Mediene
- Benet Mikhail
- Bennett James E.
- Bennett James E.
- Benson Lowell S.
- Berkinbayev Salim
- Bernabe-Ortiz Antonio
- Bettiol Heloisa
- Bezerra Jorge
- Bhagyalaxmi Aroor
- Bhargava Santosh K.
- Bia Daniel
- Biasch Katia
- Bikbov Mukharram M.
- Bista Bihungum
- Bjerregaard Peter
- Bjertness Espen
- Bjertness Marius B.
- Bjorkelund Cecilia
- Bloch Katia V.
- Blokstra Anneke
- Bo Simona
- Bobak Martin
- Boeing Heiner
- Boggia Jose G.
- Boissonnet Carlos P.
- Bojesen Stig E.
- Boker Lital Keinan
- Bonet Gorbea Mariano
- Bongard Vanina
- Bonilla-Vargas Alice
- Bopp Matthias
- Borghs Herman
- Bovet Pascal
- Boyer Christopher B.
- Braeckman Lutgart
- Brajkovich Imperia
- Branca Francesco
- Breckenkamp Jürgen
- Brenner Hermann
- Brewster Lizzy M.
- Briceno Yajaira
- Brito Miguel
- Bruno Graziella
- Bueno Gloria
- Bueno-de-Mesquita H. Bas
- Bugge Anna
- Burns Con
- Bursztyn Michael
- Cabrera de Leon Antonio
- Cacciottolo Joseph
- Cadena Leticia Hernandez
- Cameron Christine
- Can Gunay
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- Capanzana Mario V.
- Capkova Nadezda
- Capuano Eduardo
- Capuano Vincenzo
- Cardoso Viviane C.
- Carlsson Axel C.
- Carrillo-Larco Rodrigo M.
- Carvalho Joana
- Casanueva Felipe F.
- Censi Laura
- Cervantes-Loaiza Marvin
- Chadjigeorgiou Charalambos A.
- Chamukuttan Snehalatha
- Chan Angelique W.
- Chan Queenie
- Chaturvedi Himanshu K.
- Chaturvedi Nish
- Chee Miao Li
- Chen Chien-Jen
- Chen Fangfang
- Chen Huashuai
- Chen Shuohua
- Chen Zhengming
- Cheng Ching-Yu
- Cheraghian Bahman
- Chetrit Angela
- Chien Kuo-Liong
- Chiolero Arnaud
- Chiou Shu-Ti
- Chirita-Emandi Adela
- Chirlaque Maria-Dolores
- Cho Belong
- Christensen Kaare
- Christofaro Diego G.
- Chudek Jerzy
- Cifkova Renata
- Cifkova Renata
- Cinteza Eliza
- Claessens Frank
- Clarke Janine
- Clays Els
- Cohen Emmanuel
- Concin Hans
- Cooper Cyrus
- Coppinger Tara C.
- Cordeiro da Silva Bruna Goncalves
- Costanzo Simona
- Cottel Dominique
- Cowan Melanie J.
- Cowell Chris
- Craig Cora L.
- Crampin Amelia C.
- Crujeiras Ana B.
- Cruz Juan J.
- Csilla Semanova
- Cui Liufu
- Cureau Felipe V.
- Cuschieri Sarah
- D'Arrigo Graziella
- d'Orsi Eleonora
- Dallongeville Jean
- Damasceno Albertino
- Damasceno Albertino
- Danaei Goodarz
- Danaei Goodarz
- Dankner Rachel
- Dantoft Thomas M.
- Dauchet Luc
- Davletov Kairat
- De Backer Guy
- De Bacquer Dirk
- De Curtis Amalia
- de Gaetano Giovanni
- De Henauw Stefaan
- de Moura Silva Caroline Ramos
- de Oliveira Paula Duarte
- de Paiva Karina Mary
- De Ridder David
- De Smedt Delphine
- de Wit Tobias F. Rinke
- Deepa Mohan
- Deev Alexander D.
- DeGennaro Vincent Jr
- Dekkaki Imane Cherkaoui
- del Cristo Rodriguez-Perez Maria
- Delisle Helene
- Demarest Stefaan
- Dennison Elaine
- Deschamps Valerie
- Dhimal Meghnath
- Di Castelnuovo Augusto F.
- Dias-da-Costa Juvenal Soares
- Diaz Alejandro
- Dickerson Ty T.
- Dika Zivka
- Dinc Gonul Horasan
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- Doering Angela
- Doerr Marcus
- Donfrancesco Chiara
- Donoso Silvana P.
- Dorobantu Maria
- Doua Kouamelan
- Dragano Nico
- Drygas Wojciech
- Duante Charmaine A.
- Duboz Priscilla
- Duda Rosemary B.
- Dulskiene Virginija
- Dushpanova Anar
- Dzakula Aleksandar
- Dzerve Vilnis
- Dziankowska-Zaborszczyk Elzbieta
- Eddie Ricky
- Eftekhar Ebrahim
- Eggertsen Robert
- Eghtesad Sareh
- Eiben Gabriele
- Ekelund Ulf
- El Ati Jalila
- El-Khateeb Mohammad
- Eldemire-Shearer Denise
- Eliasen Marie
- Elisa Zapata Maria
- Elliott Paul
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- Elosua Roberto
- Erasmus Rajiv T.
- Erbel Raimund
- Erem Cihangir
- Eriksen Louise
- Eriksson Johan G.
- Escobedo-de la Pena Jorge
- Eslami Saeid
- Esmaeili Ali
- Evans Alun
- Ezzati Majid
- Faeh David
- Fakhretdinova Albina A.
- Fall Caroline H.
- Faramarzi Elnaz
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- Farzadfar Farshad
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- Fattahi Mohammad Reza
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- Felix Stephan B.
- Felix-Redondo Francisco J.
- Ferguson Trevor S.
- Fernandes Romulo A.
- Fernandez-Berges Daniel
- Ferrante Daniel
- Ferrao Thomas
- Ferrari Marika
- Ferrario Marco M.
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- Ferreira Haroldo S.
- Ferrer Eldridge
- Ferrieres Jean
- Figueiro Thamara Hubler
- Fink Gunther
- Fischer Krista
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- Franco Maria do Carmo
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- Frontera Guillermo
- Fuchs Flavio D.
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- Fujita Yuki
- Fumihiko Matsuda
- Furdela Viktoriya
- Furer Ariel
- Furusawa Takuro
- Gaciong Zbigniew
- Galbarczyk Andrzej
- Galenkamp Henrike
- Galvano Fabio
- Gao Jingli
- Gao Pei
- Garcia Pablo
- Garcia-de-la-Hera Manoli
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- Garnett Sarah P.
- Gaspoz Jean-Michel
- Gasull Magda
- Gazzinelli Andrea
- Gehring Ulrike
- Geleijnse Johanna M.
- George Ronnie
- Ghanbari Ali
- Ghasemi Erfan
- Gheorghe-Fronea Oana-Florentina
- Ghimire Anup
- Gialluisi Alessandro
- Giampaoli Simona
- Gieger Christian
- Gill Tiffany K.
- Giovannelli Jonathan
- Gironella Glen
- Giwercman Aleksander
- Gkiouras Konstantinos
- Glavic Mihalea Marinovic
- Goldberg Marcel
- Goldsmith Rebecca A.
- Gomes Barros Mauro Virgilio
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- Goncalves Helen
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- Gonzalez-Villalpando Clicerio
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- Gottrand Frederic
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- Gregg Edward W.
- Gregor Ronald D.
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- Grosso Giuseppe
- Gruden Gabriella
- Gu Dongfeng
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- Gudmundsson Elias F.
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- Guerrero Ramiro
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- Gunnlaugsdottir Johanna
- Gunter Marc J.
- Gupta Prakash C.
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- Gureje Oye
- Gurzkowska Beata
- Gutierrez Laura
- Gutzwiller Felix
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- Haghshenas Rosa
- Hakimi Hamid
- Halkjaer Jytte
- Hambleton Ian R.
- Hamzeh Behrooz
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- Hanif Abu A. M.
- Hantunen Sari
- Hao Jie
- Hardman Carla Meneses
- Hashemi-Shahri Seyed Mohammad
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- Hayes Alison J.
- He Jiang
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- He Yuna
- Heier Margit
- Hendriks Marleen Elisabeth
- Henrique Rafael dos Santos
- Henriques Ana
- Herrala Sauli
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- Hill Allan G.
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- Hoang Van Minh Hoang Van Minh
- Hobbs Michael
- Holdsworth Michelle
- Homayounfar Reza
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- Horta Bernardo L.
- Houti Leila
- Howitt Christina
- Htay Thein Thein
- Htet Aung Soe
- Htike Maung Maung Than
- Hu Yonghua
- Huerta Jose Maria
- Huhtaniemi Ilpo Tapani
- Huiart Laetitia
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- Jennings Garry
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- Kerimkulova Alina
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- Khanh Le Nguyen Bao Khanh Le Nguyen Bao
- Khaw Kay-Tee
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- Shimizu-Furusawa Hana
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- Slusarczyk Przemyslaw
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- Sobngwi Eugene
- Soderberg Stefan
- Soemantri Agustinus
- Sofat Reecha
- Solfrizzi Vincenzo
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- Sonestedt Emily
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- Stoeckl Doris
- Stokwiszewski Jakub
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- Sundstrom Johan
- Sundstrom Johan
- Sung Yn-Tz
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- Szklo Moyses
- Tai E. Shyong
- Tammesoo Mari-Liis
- Tamosiunas Abdonas
- Tan Eng Joo
- Tang Xun
- Tanser Frank
- Tao Yong
- Tarawneh Mohammed Rasoul
- Tarqui-Mamani Carolina B.
- Taylor Anne
- Taylor Julie
- Tebar William R.
- Tell Grethe S.
- Tello Tania
- Tham Yih Chung
- Thankappan K. R.
- Theobald Holger
- Theodoridis Xenophon
- Thijs Lutgarde
- Thinggaard Mikael
- Thomas Nihal
- Thorand Barbara
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- Trichopoulos Dimitrios
- Trichopoulou Antonia
- Trinh Oanh T. H.
- Trivedi Atul
- Tshepo Lechaba
- Tsugane Shoichiro
- Tuliakova Azaliia M.
- Tulloch-Reid Marshall K.
- Tullu Fikru
- Tuomainen Tomi-Pekka
- Tuomilehto Jaakko
- Turley Maria L.
- Twig Gilad
- Tynelius Per
- Tzourio Christophe
- Ueda Peter
- Ugel Eunice
- Ulmer Hanno
- Uusitalo Hannu M. T.
- Valdivia Gonzalo
- Valvi Damaskini
- van Dam Rob M.
- van den Born Bert-Jan
- Van der Heyden Johan
- van der Schouw Yvonne T.
- Van Herck Koen
- Van Schoor Natasja M.
- van Valkengoed Irene G. M.
- van Zutphen Elisabeth M.
- Vanderschueren Dirk
- Vanuzzo Diego
- Varbo Anette
- Varghese Cherian
- Vasan Senthil K.
- Vega Tomas
- Veidebaum Toomas
- Velasquez-Melendez Gustavo
- Veronesi Giovanni
- Verschuren W. M. Monique
- Verstraeten Roosmarijn
- Victora Cesar G.
- Viet Lucie
- Villalpando Salvador
- Vineis Paolo
- Vioque Jesus
- Virtanen Jyrki K.
- Visvikis-Siest Sophie
- Viswanathan Bharathi
- Vlasoff Tiina
- Vollenweider Peter
- Voutilainen Ari
- Vrkic Tajana Zeljkovic
- Wade Alisha N.
- Walton Janette
- Wambiya Elvis O. A.
- Wanderley Junior Rildo de Souza
- Wang Ming-Dong
- Wang Ningli
- Wang Qian
- Wang Xiangjun
- Wang Ya Xing
- Wang Ying-Wei
- Wannamethee S. Goya
- Wareham Nicholas
- Wei Wenbin
- Weres Aneta
- Werner Bo
- Whincup Peter H.
- Widhalm Kurt
- Widyahening Indah S.
- Widyahening Indah S.
- Wiecek Andrzej
- Wilks Rainford J.
- Willeit Johann
- Willeit Peter
- Williams Emmanuel A.
- Wilsgaard Tom
- Wojtyniak Bogdan
- Wong Andrew
- Wong Norazizah Ibrahim
- Wong Tien Yin
- Wong-McClure Roy A.
- Woo Jean
- Woodward Mark
- Woodward Mark
- Wu Frederick C.
- Wu Shouling
- Wyszynska Justyna
- Xu Haiquan
- Xu Liang
- Yaacob Nor Azwany
- Yan Weili
- Yang Ling
- Yang Xiaoguang
- Yang Yang
- Yasuharu Tabara
- Ye Xingwang
- Yiallouros Panayiotis K.
- Yoosefi Moein
- Yoshihara Akihiro
- You San-Lin
- Younger-Coleman Novie O.
- Yusoff Ahmad Faudzi
- Yusoff Muhammad Fadhli Mohd
- Zainuddin Ahmad A.
- Zakavi Seyed Rasoul
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zaw Ko Ko
- Zdrojewski Tomasz
- Zdrojewski Tomasz
- Zejglicova Kristyna
- Zeng Yi
- Zhang Luxia
- Zhang Zhen-Yu
- Zhao Dong
- Zhao Ming-Hui
- Zhen Shiqi
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhu Dan
- Zins Marie
- Zitt Emanuel
- Zocalo Yanina
- Zoghlami Nada
- Zuniga Cisneros Julio
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
BACKGROUND: Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories. METHODS: We used data from 1990 to 2019 on people aged 30-79 years from population-representative studies with measurement of blood pressure and data on blood pressure treatment. We defined hypertension as having systolic blood pressure 140 mm Hg or greater, diastolic blood pressure 90 mm Hg or greater, or taking medication for hypertension. We applied a Bayesian hierarchical model to estimate the prevalence of hypertension and the proportion of people with hypertension who had a previous diagnosis (detection), who were taking medication for hypertension (treatment), and whose hypertension was controlled to below 140/90 mm Hg (control). The model allowed for trends over time to be non-linear and to vary by age. FINDINGS: The number of people aged 30-79 years with hypertension doubled from 1990 to 2019, from 331 (95% credible interval 306-359) million women and 317 (292-344) million men in 1990 to 626 (584-668) million women and 652 (604-698) million men in 2019, despite stable global age-standardised prevalence. In 2019, age-standardised hypertension prevalence was lowest in Canada and Peru for both men and women; in Taiwan, South Korea, Japan, and some countries in western Europe including Switzerland, Spain, and the UK for women; and in several low-income and middle-income countries such as Eritrea, Bangladesh, Ethiopia, and Solomon Islands for men. Hypertension prevalence surpassed 50% for women in two countries and men in nine countries, in central and eastern Europe, central Asia, Oceania, and Latin America. Globally, 59% (55-62) of women and 49% (46-52) of men with hypertension reported a previous diagnosis of hypertension in 2019, and 47% (43-51) of women and 38% (35-41) of men were treated. Control rates among people with hypertension in 2019 were 23% (20-27) for women and 18% (16-21) for men. In 2019, treatment and control rates were highest in South Korea, Canada, and Iceland (treatment >70%; control >50%), followed by the USA, Costa Rica, Germany, Portugal, and Taiwan. Treatment rates were less than 25% for women and less than 20% for men in Nepal, Indonesia, and some countries in sub-Saharan Africa and Oceania. Control rates were below 10% for women and men in these countries and for men in some countries in north Africa, central and south Asia, and eastern Europe. Treatment and control rates have improved in most countries since 1990, but we found little change in most countries in sub-Saharan Africa and Oceania. Improvements were largest in high-income countries, central Europe, and some upper-middle-income and recently high-income countries including Costa Rica, Taiwan, Kazakhstan, South Africa, Brazil, Chile, Turkey, and Iran. INTERPRETATION: Improvements in the detection, treatment, and control of hypertension have varied substantially across countries, with some middle-income countries now outperforming most high-income nations. The dual approach of reducing hypertension prevalence through primary prevention and enhancing its treatment and control is achievable not only in high-income countries but also in low-income and middle-income settings. FUNDING: WHO
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants
- Author
- Abarca-Gomez Leandra
- Abdeen Ziad A.
- Abu-Rmeileh Niveen M.
- Acosta-Cazares Benjamin
- Adams Robert J.
- Aekplakorn Wichai
- Afsana Kaosar
- Afzal Shoaib
- Agdeppa Imelda A.
- Aghazadeh-Attari Javad
- Aguilar-Salinas Carlos A.
- Agyemang Charles
- Ahmad Noor Ani
- Ahmadi Ali
- Ahmadi Naser
- Ahmadi Nastaran
- Ahmadizar Fariba
- Ahmed Soheir H.
- Ahrens Wolfgang
- Ajlouni Kamel
- Al Nsour Mohannad
- Al-Raddadi Rajaa
- Alarouj Monira
- AlBuhairan Fadia
- AlDhukair Shahla
- Ali Mohamed M.
- Alkandari Abdullah
- Alkerwi Ala'a
- Allin Kristine
- Aly Eman
- Amarapurkar Deepak N.
- Amougou Norbert
- Amouyel Philippe
- Andersen Lars Bo
- Anderssen Sigmund A.
- Andre Moura-dos-Santos Marcos
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Ansong Daniel
- Aounallah-Skhiri Hajer
- Araujo Joana
- Ariansen Inger
- Aris Tahir
- Arku Raphael E.
- Arlappa Nimmathota
- Aryal Krishna K.
- Aspelund Thor
- Assah Felix K.
- Assuncao Maria Cecilia F.
- Auvinen Juha
- Avdicova Maria
- Azevedo Ana
- Azimi-Nezhad Mohsen
- Azizi Fereidoun
- Azmin Mehrdad
- Babu Bontha V.
- Bahijri Suhad
- Balakrishna Nagalla
- Balanova Yulia
- Balanova Yulia
- Bamoshmoosh Mohamed
- Banach Maciej
- Banadinovic Maja
- Bandosz Piotr
- Banegas Jose R.
- Bao Khanh Le Nguyen
- Bao Tran Quoc
- Baran Joanna
- Barbagallo Carlo M.
- Barcelo Alberto
- Barkat Amina
- Barreto Marta
- Barros Aluisio J. D.
- Bartosiewicz Anna
- Basit Abdul
- Bastos Joao Luiz D.
- Bata Iqbal
- Batieha Anwar M.
- Batyrbek Assembekov
- Baur Louise A.
- Beaglehole Robert
- Bebakar Wan Mohamad Wan
- Belavendra Antonisamy
- Ben Romdhane Habiba
- Benchekor Sounnia Mediene
- Benet Mikhail
- Bennett James E.
- Bennett James E.
- Benson Lowell S.
- Berkinbayev Salim
- Bernabe-Ortiz Antonio
- Bettiol Heloisa
- Bezerra Jorge
- Bhagyalaxmi Aroor
- Bhargava Santosh K.
- Bia Daniel
- Biasch Katia
- Bikbov Mukharram M.
- Bista Bihungum
- Bjerregaard Peter
- Bjertness Espen
- Bjertness Marius B.
- Bjorkelund Cecilia
- Bloch Katia V.
- Blokstra Anneke
- Bo Simona
- Bobak Martin
- Boeing Heiner
- Boggia Jose G.
- Boissonnet Carlos P.
- Bojesen Stig E.
- Boker Lital Keinan
- Bonet Gorbea Mariano
- Bongard Vanina
- Bonilla-Vargas Alice
- Bopp Matthias
- Borghs Herman
- Bovet Pascal
- Boyer Christopher B.
- Braeckman Lutgart
- Brajkovich Imperia
- Branca Francesco
- Breckenkamp Juergen
- Brenner Hermann
- Brewster Lizzy M.
- Briceno Yajaira
- Brito Miguel
- Bruno Graziella
- Bueno Gloria
- Bueno-de-Mesquita H. Bas
- Bugge Anna
- Burns Con
- Bursztyn Michael
- Cabrera de Leon Antonio
- Cacciottolo Joseph
- Cadena Leticia Hernandez
- Cameron Christine
- Can Gunay
- Candido Ana Paula C.
- Capanzana Mario V.
- Capkova Nadezda
- Capuano Eduardo
- Capuano Vincenzo
- Cardoso Viviane C.
- Carlsson Axel C.
- Carrillo-Larco Rodrigo M.
- Carvalho Joana
- Casanueva Felipe F.
- Censi Laura
- Cervantes-Loaiza Marvin
- Chadjigeorgiou Charalambos A.
- Chamukuttan Snehalatha
- Chan Angelique W.
- Chan Queenie
- Chaturvedi Himanshu K.
- Chaturvedi Nish
- Chee Miao Li
- Chen Chien-Jen
- Chen Fangfang
- Chen Huashuai
- Chen Shuohua
- Chen Zhengming
- Cheng Ching-Yu
- Cheraghian Bahman
- Chetrit Angela
- Chien Kuo-Liong
- Chiolero Arnaud
- Chiou Shu-Ti
- Chirita-Emandi Adela
- Chirlaque Maria-Dolores
- Cho Belong
- Christensen Kaare
- Christofaro Diego G.
- Chudek Jerzy
- Cifkova Renata
- Cifkova Renata
- Cinteza Eliza
- Claessens Frank
- Clarke Janine
- Clays Els
- Cohen Emmanuel
- Collaboration NCD Risk Factor
- Concin Hans
- Cooper Cyrus
- Coppinger Tara C.
- Cordeiro da Silva Bruna Goncalves
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- Wong Norazizah Ibrahim
- Wong Tien Yin
- Wong-McClure Roy A.
- Woo Jean
- Woodward Mark
- Woodward Mark
- Wu Frederick C.
- Wu Shouling
- Wyszynska Justyna
- Xu Haiquan
- Xu Liang
- Yaacob Nor Azwany
- Yan Weili
- Yang Ling
- Yang Xiaoguang
- Yang Yang
- Yasuharu Tabara
- Ye Xingwang
- Yiallouros Panayiotis K.
- Yoosefi Moein
- Yoshihara Akihiro
- You San-Lin
- Younger-Coleman Novie O.
- Yusoff Ahmad Faudzi
- Yusoff Muhammad Fadhli Mohd
- Zainuddin Ahmad A.
- Zakavi Seyed Rasoul
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zaw Ko Ko
- Zdrojewski Tomasz
- Zdrojewski Tomasz
- Zejglicova Kristyna
- Zeng Yi
- Zhang Luxia
- Zhang Zhen-Yu
- Zhao Dong
- Zhao Ming-Hui
- Zhen Shiqi
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhu Dan
- Zins Marie
- Zitt Emanuel
- Zocalo Yanina
- Zoghlami Nada
- Zuniga Cisneros Julio
- Publication venue
- ELSEVIER SCIENCE INC
- Publication date
- 01/01/2021
- Field of study
Background Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories. Methods We used data from 1990 to 2019 on people aged 30-79 years from population-representative studies with measurement of blood pressure and data on blood pressure treatment. We defined hypertension as having systolic blood pressure 140 mm Hg or greater, diastolic blood pressure 90 mm Hg or greater, or taking medication for hypertension. We applied a Bayesian hierarchical model to estimate the prevalence of hypertension and the proportion of people with hypertension who had a previous diagnosis (detection), who were taking medication for hypertension (treatment), and whose hypertension was controlled to below 140/90 mm Hg (control). The model allowed for trends over time to be non-linear and to vary by age. Findings The number of people aged 30-79 years with hypertension doubled from 1990 to 2019, from 331 (95% credible interval 306-359) million women and 317 (292-344) million men in 1990 to 626 (584-668) million women and 652 (604-698) million men in 2019, despite stable global age-standardised prevalence. In 2019, age-standardised hypertension prevalence was lowest in Canada and Peru for both men and women; in Taiwan, South Korea, Japan, and some countries in western Europe including Switzerland, Spain, and the UK for women; and in several low-income and middle-income countries such as Eritrea, Bangladesh, Ethiopia, and Solomon Islands for men. Hypertension prevalence surpassed 50% for women in two countries and men in nine countries, in central and eastern Europe, central Asia, Oceania, and Latin America. Globally, 59% (55-62) of women and 49% (46-52) of men with hypertension reported a previous diagnosis of hypertension in 2019, and 47% (43-51) of women and 38% (35-41) of men were treated. Control rates among people with hypertension in 2019 were 23% (20-27) for women and 18% (16-21) for men. In 2019, treatment and control rates were highest in South Korea, Canada, and Iceland (treatment >70%; control >50%), followed by the USA, Costa Rica, Germany, Portugal, and Taiwan. Treatment rates were less than 25% for women and less than 20% for men in Nepal, Indonesia, and some countries in sub-Saharan Africa and Oceania. Control rates were below 10% for women and men in these countries and for men in some countries in north Africa, central and south Asia, and eastern Europe. Treatment and control rates have improved in most countries since 1990, but we found little change in most countries in sub-Saharan Africa and Oceania. Improvements were largest in high-income countries, central Europe, and some upper-middle-income and recently high-income countries including Costa Rica, Taiwan, Kazakhstan, South Africa, Brazil, Chile, Turkey, and Iran. Interpretation Improvements in the detection, treatment, and control of hypertension have varied substantially across countries, with some middle-income countries now outperforming most high-income nations. The dual approach of reducing hypertension prevalence through primary prevention and enhancing its treatment and control is achievable not only in high-income countries but also in low-income and middle-income settings. Copyright (C) 2021 World Health Organization; licensee Elsevier
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