4 research outputs found
Significant benefits of AIP testing and clinical screening in familial isolated and young-onset pituitary tumors
- Author
- Agnieszka Lebek-Szatanska
- Ajith V Kumar
- Akira Matsuno
- Aled Rees
- Alex Bickerton
- Ali Imran
- Alia Munir
- Alper Gürlek
- Amar Agha
- Amy Ronaldson
- Anand Kumar
- Andrew Green
- Andrew Levy
- Angelos Kyriaku
- Anna Aulinas-Masó
- Anna Spada
- Anne Katrin Lampe
- Anthony P Goldstone
- Antonia Brooke
- António Ribeiro de Oliveira
- Aparna Pal
- Ariel Barkan
- Arla Ogilivie
- Ashley B Grossman
- Astrid Weber
- Atik Baborie
- Attila Patócs
- Barbara McGowan
- Barbara Mosterman
- Beatriz S Soares
- Beckers
- Bernard Khoo
- Bijay Vaidya
- Biju Jose
- Blair
- Brede Swantje
- Brew Atkinson
- Britt Edén-Engström
- Caimari
- Candy Sze
- Carmen Bernal-González
- Carmen Georgescu
- Caroline Brain
- Catherine Choong
- Catherine Gilkes
- Catherine Lyons
- Catherine Patterson
- Cathy Kiraly-Borri
- Cazabat
- Celia Rodd
- Chandi Idampitiya
- Charlotte Höybye
- Cheri Deal
- Chris Thompson
- Christian Strasburger
- Christina Daousi
- Christine Burren
- Christof Schöfl
- Chung Thong Lim
- Colin Johnston
- Corin Badiu
- Cuny
- Daly
- Daly
- Daly
- Daly
- Daly
- Damian G Morris
- Daniel Cuthbertson
- Darko Kastelan
- David A Hilton
- David Carty
- David Collier
- David Cove
- de Laat
- Debbie Shears
- Dinesh Nagi
- Dominic Cavlan
- Donato Iacovazzo
- Dragana Miljic
- Dutta
- Edward R Laws
- Elaine Tham
- Eleanor Hay
- Eleanor Lin
- Elena Aflorei
- Elizabeth Crowne
- Elizabeth Forsythe
- Ellard
- Emese Mezősi
- Evelien Gevers
- Farida Chentli
- Federico Roncaroli
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- Hamish Courtney
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- Marques
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- Paul Dimitri
- Pedro Marques
- Peter Bates
- Peter Clayton
- Peter J Trainer
- Peter Pullan
- Peter Shane Hamblin
- Philip Harding
- Philip Yeoh
- Philippa Carter
- Philippe F Backeljauw
- Pierre Bouloux
- Pinaki Dutta
- Prakash Abraham
- Preda
- Péter Igaz
- Rajesh V Thakker
- Ramesh Nair
- Rasa Verkauskiene
- Richard J M Ross
- Richard N Clayton
- Richard Nelson
- Richard Quinton
- Richards
- Robert D Murray
- Robert Skelly
- Robertas Knispelis
- Roberto Salvatori
- Roger Brown
- Ronald M Lechan
- Rosalind Eeles
- Rostomyan
- Sachith Mettananda
- Salenave
- Scott A Akker
- Sema Yarman
- Serban Radian
- Shereen Ezzat
- Shozo Yamada
- Sian Ellard
- Silvia Modenesi
- Simon H Pearce
- Simon Howell
- Simon J Aylwin
- Simona Fica
- Siobhán E McQuaid
- Stefan Fischli
- Stephanie Baldeweg
- Stephen Gallacher
- Steve Ball
- Steve M Orme
- Steven Hunter
- Stylianos Tsagarakis
- Sujatha Jagadeesh
- Susan Stewart
- Susan Webb
- Svetozar Damjanovic
- Sándor Alföldi
- Taffy Makaya
- Takeo Iwata
- Tara Kearney
- Teng-Teng Chung
- Thakker
- Theodore Friedman
- Tichomirowa
- Tim Cheetham
- Trevor A Howlett
- Tristan Richardson
- Vaclav Hana
- Valerie Renals
- Vera Popovic
- Vierimaa
- Vladimir Vaks
- Warrick J Inder
- Wiebke Arlt
- William Drake
- William Foulkes
- Williams
- Winnie Ho
- Wu
- Publication venue
- 'The Endocrine Society'
- Publication date
- 01/06/2020
- Field of study
Context
Germline mutations in the aryl hydrocarbon receptor-interacting protein (AIP) gene are responsible for a subset of familial isolated pituitary adenoma (FIPA) cases and sporadic pituitary neuroendocrine tumors (PitNETs).
Objective
To compare prospectively diagnosed AIP mutation-positive (AIPmut) PitNET patients with clinically presenting patients and to compare the clinical characteristics of AIPmut and AIPneg PitNET patients.
Design
12-year prospective, observational study.
Participants & Setting
We studied probands and family members of FIPA kindreds and sporadic patients with disease onset ≤18 years or macroadenomas with onset ≤30 years (n = 1477). This was a collaborative study conducted at referral centers for pituitary diseases.
Interventions & Outcome
AIP testing and clinical screening for pituitary disease. Comparison of characteristics of prospectively diagnosed (n = 22) vs clinically presenting AIPmut PitNET patients (n = 145), and AIPmut (n = 167) vs AIPneg PitNET patients (n = 1310).
Results
Prospectively diagnosed AIPmut PitNET patients had smaller lesions with less suprasellar extension or cavernous sinus invasion and required fewer treatments with fewer operations and no radiotherapy compared with clinically presenting cases; there were fewer cases with active disease and hypopituitarism at last follow-up. When comparing AIPmut and AIPneg cases, AIPmut patients were more often males, younger, more often had GH excess, pituitary apoplexy, suprasellar extension, and more patients required multimodal therapy, including radiotherapy. AIPmut patients (n = 136) with GH excess were taller than AIPneg counterparts (n = 650).
Conclusions
Prospectively diagnosed AIPmut patients show better outcomes than clinically presenting cases, demonstrating the benefits of genetic and clinical screening. AIP-related pituitary disease has a wide spectrum ranging from aggressively growing lesions to stable or indolent disease course
Policing Terrorists in the Community
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Landscape of Familial Isolated and Young-Onset Pituitary Adenomas: Prospective Diagnosis in AIP Mutation Carriers.
- Author
- Ajith V. Kumar
- Akira Matsuno
- Alia Munir
- Alper Gürlek
- Amar Agha
- Anna Aulinas-Masó
- Anna Spada
- Anthony P. Goldstone
- Antônio Ribeiro-Oliveira
- Ariel Barkan
- Arla Ogilvie
- Ashley B. Grossman
- Astrid Weber
- Attila Patócs
- Barbara McGowan
- Beatriz S. Soares
- Bernard Khoo
- Brew Atkinson
- Britt Edén-Engström
- Carmen Bernal-González
- Catherine Patterson
- Cathy Kiraly-Borri
- Celia Rodd
- Charlotte Höybye
- Chris Thompson
- Christian Strasburger
- Christina Daousi
- Christof Schöfl
- Corin Badiu
- Damian G. Morris
- Daniel Cuthbertson
- Daniel Flanagan
- Daniel Tilley
- Darko Kastelan
- Debbie Shears
- Donato Iacovazzo
- Dr Michael O. Thorner
- Dragana Miljic
- Edit Gláz
- Edward R. Laws
- Elaine Tham
- Elena D. Aflorei
- Elizabeth Crowne
- Emese Mezősi
- Evelien Gevers
- Farida Chentli
- Federico Roncaroli
- Felicity Kaplan
- Fiona Ryan
- Francesca Pecori Giraldi
- Francesca Swords
- Francesco Ferraù
- G. Michael Besser
- Giampaolo Trivellin
- Gregory Kaltsas
- Gul Bano
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- Karen Stals
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- Krzysztof Lewandowski
- Larisa Dzeranova
- Laura C. Hernández-Ramírez
- Laura De Marinis
- Lawrence A. Frohman
- Lisa Bradley
- Lisa Nachtigall
- Louise Emmerson
- Louise Izatt
- Lynn Greenhalgh
- Madalina Musat
- Margaret De Castro
- Maria Elfving
- Maria Elisabeth Street
- Maria Fleseriu
- Marianne Elston
- Marija Pfeifer
- Marinella Tzanela
- Mark Cohen
- Mark E. Molitch
- Mark Gurnell
- Mehtap Cakir
- Mehul Dattani
- Michael Buchfelder
- Michael Powell
- Michelle Katz
- Miklos Goth
- Miklós Tóth
- Miles J. Levy
- Milica Medic-Stojanoska
- Mirtha Guitelman
- Moisés Mercado-Atri
- Márta Korbonits
- Mônica R. Gadelha
- Nadezhda Dalantaeva
- Naomi Fersht
- Natalie Canham
- Nicola N. Zammitt
- Nicola Poplawski
- Niki Karavitaki
- Niki Maartens
- Nina Musolino
- Noel Somasundaram
- Pamela U. Freda
- Patricia Gallego
- Patrick J. Morrison
- Paul Carroll
- Peter Igaz
- Peter J. Trainer
- Peter Pullan
- Philip Yeoh
- Philippe F. Backeljauw
- Pierre Bouloux
- Pinaki Dutta
- Plamena Gabrovska
- Rajesh V. Thakker
- Rasa Verkauskiene
- Richard N. Clayton
- Richard Quinton
- Robert D. Murray
- Robertas Knispelis
- Roberto Salvatori
- Ronald M. Lechan
- Rosalind Eeles
- Scott A. Akker
- Sema Yarman
- Serban Radian
- Shozo Yamada
- Sian Ellard
- Silvia Modenesi
- Simon H. Pearce
- Simon J. Aylwin
- Simona Fica
- Siobhán E. McQuaid
- Stefan Fischli
- Stephanie Baldeweg
- Steve M. Orme
- Steven Hunter
- Stylianos Tsagarakis
- Sujatha Jagadeesh
- Susan M. Webb
- Susan Stewart
- Sándor Alföldi
- Takeo Iwata
- Tara Kearney
- Theodore Friedman
- Tim Cheetham
- Trevor A. Howlett
- Trevor Cole
- Vera Popovic
- Vladimir Vaks
- Warrick J. Inder
- Wiebke Arlt
- William Drake
- Publication venue
- 'The Endocrine Society'
- Publication date
- 01/01/2015
- Field of study
Familial isolated pituitary adenoma (FIPA) due to aryl hydrocarbon receptor interacting protein (AIP) gene mutations is an autosomal dominant disease with incomplete penetrance. Clinical screening of apparently unaffected AIP mutation (AIPmut) carriers could identify previously unrecognized disease.This article is freely available via PubMed Central. Click on the 'Additional Link' above to access the full text
1994 Annual Selected Bibliography: Asian American Studies and the Crisis of Practice
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- Abe Jennifer
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- Guillaumin Colette
- Haddad
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- Hansen Arthur A
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- Hau
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- Hawaii Business
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- Hawaii Hongwanji Ministers
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- History
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- Holt Grace D
- Hom Alice Y
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- Hong Jean Y
- Hong Minne
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- Hood Marlowe
- Hori Victor Sogen
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- Huang
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- Huang Karen
- Huang Larke Nahme
- Huggan Graham
- Hughes Diane
- Huie Wing Young
- Hundal Sukhwant S
- Hutchison Ray
- Huttlinger Kathleen
- Hyer Eric
- Ichioka Yuji
- Igoa Cristina
- Iino Masako
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- Immigration America's Newcomers
- Industry
- Ingrassia Michele
- Interracial Identity
- Ip D. F.
- Irizarry Karen Kathleen
- Irwin Richard A
- Isajiw Wsevolod W
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- Islam Naheed
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- Joshi Aida A
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- Ka
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- Kahn Joan R
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- Kivisto Peter
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- Kleiber Margrethe S. C.
- Klootwijk Eeuwout
- Knox Robert J
- Kodama Masaaki
- Koehn Sharon Denise
- Koh Howard Kyongju
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- Korean YellowPages
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- Kwa Lydia
- Kwong Peter
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- Lai Walton Look
- Lam Andrew
- Lam K.-C.
- Lam Leo L
- Lam Maivbn Clech
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- Lange Cynthia Juarez
- Lary Diana
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- Lau Evelyn
- Lau Wendy
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- Le Tri Huu
- Lee
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- Lee Clifford
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- Lee Elisa
- Lee Elisa
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- Lee Gus
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- Leong Frederick T. L.
- Leong Frederick T. L.
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- Leong Russell C
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- Leung S. Alvin
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- Li
- Li Guangming
- Li X. L.
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- Light I.
- Light I.
- Lim Gerard
- Lim Shirley
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- Lippi-Green Rosina
- Lipske Mike
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- Little Gom-Benn
- Liu Aimee E
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- Lo S. D.
- Lopez I. F.
- Los Angeles County
- Lott Juanita Tamayo
- Louie
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- Madden Ryan
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- Mak Anita S
- Malicky Grace V
- Maltz Earl M
- Manalansan Martin F. IV.
- Mandell Phyllis Levy
- Mangaoang Gil
- Manley Theodoric Jr
- Marable Manning
- Marie Calude-Valentin
- Marignay Bisola
- Martin
- Martinez Ramiro
- Mason Jim
- Massey Douglas S
- Masson Mireille Andree
- Matejko Alexander J
- Mathis Darlene
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- Menton
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- Multicultural History Society on Ontario 12
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- National Asian American Telecommunications Association.
- National Asian Pacific American Legal Consortium.
- Naturalization Service
- Nautu Dorri
- Nayyar Deepak
- Nee Victor
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- San Juan E. Jr.
- San Juan E. Jr.
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- Santos Bienvenido
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- Schoenberger Karl
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- Selected Bibliography
- Sensitivity
- Serran Tony
- Serxner Seth
- Sev'er Aysan
- Sexton
- Sexton Ken
- Sexton Ken
- Shaffer Donald R
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- Shah N.
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- Shimabukuro Bob
- Shimizu Yon
- Shin Kyung Rim
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- Sovereignty
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- Taylor Lawrence Douglas H
- TDR
- Tehranian Katharine
- Tehranian Majid
- The Filipino Directory
- The Peoples Multicultural Almanac
- the United States
- The Western Massachusetts Vietnamese Association Directory (Springfield Massachusetts
- Thobani Sunera
- Tien Liang
- Tirrito Terry
- Tobin Jeffrey
- Tohmatsu Akiko Judith
- Tong Benson
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- Tran Thanh V
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- Trevison Catherine
- Truong Monique
- Tsang Daniel C
- Tseng Yen-Fen
- Tsuchida John Nobuya
- Turner Marlene
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- Tworkov Helen
- U.S. Department of State
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- Ueda Reed
- Uehara Edwina S
- Ueki Teruyo
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- Vander Kathryn
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- Vera Arleen
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- Vietnamese Consumers
- Villalba
- Volpp Leti
- Wake Barbara
- Waldinger Roger
- Waldinger Roger
- Waldinger Roger
- Wallace Patricia
- Walter Pierre
- Walz Eric
- Wang
- Wang Gungwu
- Wang Linna
- Wang Ping
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- Wetherell
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- Wial Howard
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- Wilkinson Alec
- Willard Walter
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- Wolf Eric R
- Wong Cynthia
- Wong Deborah
- Wong Gil
- Wong L. Mun.
- Wong William
- Wong-Liane Eirene Ming
- Woo Alan H
- Woods Nancy Fugate
- Workplace
- Wright Debbie Hippolite
- Wright Robert E
- Wu Edna
- Wu Jenai
- Wu T. C.
- Xiong Phua
- Ya Va Thai
- Yamamoto Hisaye
- Yamamoto Joe
- Yamamoto Yasushi
- Yamanaka Keiko
- Yamanaka Lois-Ann
- Yamashita Kanshi Stanley
- Yamato Alexander
- Yamauchi Wakako
- Yan Wenfan
- Yang Dao
- Yang Jeff
- Yang P.
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- Yang Philip Q
- Yang Xiaoyun
- Yasmin Marziya
- Yau Jenny
- Ye Weili
- Yee A. H.
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- Yeh May
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- Yu Diana
- Yu Eui-Young
- Yu M. C.
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- Zaharlick Amy
- Zane Nolan
- Zane Nolan
- Zane Nolan
- Zhou Min
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- Zlotkin Hania
- Zuvekas Ann
- Publication venue
- 'UCLA American Indian Studies Center'
- Publication date
- Field of study