Sustainable energy use in houses : will the energy use increase with time? : study of literature and computer estimations

Abstract in UndeterminedThis report is a study of literature found in the field of energy use in single-family houses. It is to be regarded as a first phase, part of the project "Sustainable energy use in houses". The literature examined refers to, predominantly, Swedish conditions, including Swedish building technique and the Nordic climate. The objectives of the report are to present topics of interest, found in literature, regarding: (1) The energy use in houses, especially modern single-family houses. (2) The performance over time for building components and services affecting the energy use in houses. (3) The influence of the residents of the house on the energy use

User-Centric Measures of the Perceived Light Qualities of Lighting Products

Nowadays, lighting planning is predominantly determined by the need to meet physically measurable requirements that are often based on current lighting standards. However, meeting the minimum technical requirements of the standards is no guarantee for a visually appealing light environment. Instead, requirements based on perceived light qualities also need to be included to achieve better user comfort. Taking perception-based qualities into consideration when creating a light environment is, for many, not an easy task. In addition, a common terminology for perceived light qualities is currently lacking, both in industry and in research. The aim of this paper is, therefore, to explore how perceived light qualities of white light sources can be described when employing user-centric measures. The focus was on the qualities of light colour and diffuse and distinct light since these qualities have a great impact on the visual impression of light. The perception was assessed by applying analytical sensory analysis to lighting products, a method found to be promising in previous work. The methodology is based on analytical measurement by the human senses, which is particularly valuable when developing a general terminology. Since sensory analysis is still quite new to the topic of lighting, the applicability of using the methodology to assess lighting in a real context was also investigated. The results of the studies showed that the perception of light qualities can be described using further concepts in addition to those currently used. For light colour, the concepts of reddish, bluish, yellowish, and greenish light colours proved suitable for providing a richer description of the quality. The concepts of diffuse and distinct light satisfactorily captured variations in light contrast produced by shadows, reflections, and sparkles. In addition, the studies revealed that analytical sensory analysis was applicable for assessing the perception of lighting in a real-world context. The latter means that knowledge gained in the laboratory can be translated into real environments. The user-centric measures investigated in this paper have contributed to the terminology related to perceived light qualities. These can complement the physical measures in lighting planning to promote light environments that are not only energy efficient and meet technical requirements, but also cater for increased user comfort. Doi: 10.28991/ESJ-2023-07-02-022 Full Text: PD

Freedom from within : seeking generating sets for free groups

Since the 1870's, mathematicians have had only one real tool to help identify when a group contains free subgroups: the Klein Criterion. While powerful and elegant, there are cases when this theorem does not prove helpful. In order to apply it, we must have a candidate set that could generate a free group. This is no longer the case. The Sunic Criterion is a new theorem discovered by Zoran Sunic in 2013, and it does not require us to have a candidate for a generating set beforehand! In theory, this could allow mathematicians access to a host of groups which until now have been out of reach. In this thesis we use this new theorem to reprove that certain groups contain free subgroups and expand upon it showing that it can also be used to nd explicit generating sets for locally free groups. Having done this, we nd explicit generat- ing sets for locally free subgroups in PSL2(Z) and Aut(R+): We also explore the conditions of this new theorem.

Correlation of the NBME Advanced Clinical Examination in EM and the National EM M4 exams

Introduction Since 2011 two online, validated exams for fourth-year emergency medicine (EM) students have been available (National EM M4 Exams). In 2013 the National Board of Medical Examiners offered the Advanced Clinical Examination in Emergency Medicine (EM-ACE). All of these exams are now in widespread use; however, there are no data on how they correlate. This study evaluated the correlation between the EM-ACE exam and the National EM M4 Exams. Methods From May 2013 to April 2014 the EM-ACE and one version of the EM M4 exam were administered sequentially to fourth-year EM students at five U.S. medical schools. Data collected included institution, gross and scaled scores and version of the EM M4 exam. We performed Pearson’s correlation and random effects linear regression. Results 303 students took the EM-ACE and versions 1 (V1) or 2 (V2) of the EM M4 exams (279 and 24, respectively). The mean percent correct for the exams were as follows: EM-ACE 74.8 (SD-8.83), V1 83.0 (SD-6.41), V2 78.5 (SD-7.70). Pearson’s correlation coefficient for the V1/EM-ACE was 0.51 (0.42 scaled) and for the V2/EM-ACE was 0.59 (0.41 scaled). The coefficient of determination for V1/EM-ACE was 0.72 and for V2/EM-ACE = 0.71 (0.86 and 0.49 for scaled scores). The R-squared values were 0.25 and 0.30 (0.18 and 0.13, scaled), respectively. There was significant cluster effect by institution. Conclusion There was moderate positive correlation of student scores on the EM-ACE exam and the National EM M4 Exams

A network analysis to identify mediators of germline-driven differences in breast cancer prognosis.

Identifying the underlying genetic drivers of the heritability of breast cancer prognosis remains elusive. We adapt a network-based approach to handle underpowered complex datasets to provide new insights into the potential function of germline variants in breast cancer prognosis. This network-based analysis studies ~7.3 million variants in 84,457 breast cancer patients in relation to breast cancer survival and confirms the results on 12,381 independent patients. Aggregating the prognostic effects of genetic variants across multiple genes, we identify four gene modules associated with survival in estrogen receptor (ER)-negative and one in ER-positive disease. The modules show biological enrichment for cancer-related processes such as G-alpha signaling, circadian clock, angiogenesis, and Rho-GTPases in apoptosis

Relevamiento de la Red Federal de Género y Diversidades del CONICET 2021

La creación de la Red Federal de Género y Diversidades busca potenciar la mirada de género en las producciones científicas y tecnológicas de todas las disciplinas y en sus prácticas profesionales, identificar las capacidades existentes generando un espacio de intercambio y planeamiento entre investigadoras e investigadores, becarias/os, tomadores/as de decisiones y gestoras/es de las políticas públicas. También busca canalizar las demandas que llegan al organismo y promover la transferencia de conocimiento, capacidades y desarrollo de tecnología desde el CONICET hacia distintos sectores públicos y privados. Muy especialmente, busca colaborar con los grupos dedicados a la investigación en género y diversidades para facilitar su sostenimiento como interlocutores de referencia temática. El objetivo de este relevamiento fue: Elaborar un mapa federal e interdisciplinario de investigadoras e investigadores, becarias/os y personal del CONICET que problematizan temáticas de género y diversidades, tanto en producciones académicas como en prácticas y experiencias específicas dentro de los ámbitos y disciplinas en las que se desenvuelven.Fil: Gil, Ana Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Ciencias Humanas, Sociales y Ambientales; ArgentinaFil: Hiller, Renata. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Patagonia "San Juan Bosco". Facultad de Humanidades y Ciencias Sociales - Sede Comodoro; ArgentinaFil: Lomascolo, Silvia Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Tucumán. Facultad de Ciencias Naturales e Instituto Miguel Lillo. Laboratorio de Investigaciones Ecológicas de las Yungas; ArgentinaFil: Moisset de Espanes, Ines. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Arquitectura y Urbanismo. Instituto de Espacialidad Humana; ArgentinaFil: Pérez, Moira Patricia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Instituto de Filosofía "Dr. Alejandro Korn"; ArgentinaFil: Spataro, Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Sociales. Instituto de Investigaciones "Gino Germani"; ArgentinaFil: Torricella, Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Humanidades. Instituto de Investigaciones Sobre Sociedades, Territorios y Culturas (istec); ArgentinaFil: Vaggione, Juan Marco. Universidad Nacional de Córdoba. Centro de Investigaciones Jurídicas y Sociales. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones Jurídicas y Sociales; ArgentinaFil: Varela, Cecilia Ines. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Instituto de Ciencias Antropológicas; ArgentinaFil: Vila, Bibiana Leonor. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Sociales; Argentin

Faculty of Social Communication. #2

Los temas de amplían y su tratamineto mejora. La colaboración aumenta, en la medida en la cual la revista deja de ser la posibilidad de quedarse en un fugaz entusiamo pasajero, para convertirse en una publicación periódica.Comunicación social: ¡acceso o participación?. - 7 La vida cotidiana o la muerte de la realidad espiritual. - 12 El pensamiento verbal. - 17 El cura, el pastuso y las tejedoras. - 32 Hablemos sobre la panela. - 36 Los cronistas de tierra firme. - 41 Los temas del universo en Borgues. - 44 Nuestra literatura infantil: ficciones de una historia. - 48 El universo Bumangues. - 54 Reseñas. - 64The themes expand and their treatment improves. The collaboration increases, to the extent that the magazine ceases to be the possibility of staying in a fleeting passing enthusiasm, to become a periodic publication

Genome-wide association study of germline variants and breast cancer-specific mortality.

BackgroundWe examined the associations between germline variants and breast cancer mortality using a large meta-analysis of women of European ancestry.MethodsMeta-analyses included summary estimates based on Cox models of twelve datasets using ~10.4 million variants for 96,661 women with breast cancer and 7697 events (breast cancer-specific deaths). Oestrogen receptor (ER)-specific analyses were based on 64,171 ER-positive (4116) and 16,172 ER-negative (2125) patients. We evaluated the probability of a signal to be a true positive using the Bayesian false discovery probability (BFDP).ResultsWe did not find any variant associated with breast cancer-specific mortality at P < 5 × 10-8. For ER-positive disease, the most significantly associated variant was chr7:rs4717568 (BFDP = 7%, P = 1.28 × 10-7, hazard ratio [HR] = 0.88, 95% confidence interval [CI] = 0.84-0.92); the closest gene is AUTS2. For ER-negative disease, the most significant variant was chr7:rs67918676 (BFDP = 11%, P = 1.38 × 10-7, HR = 1.27, 95% CI = 1.16-1.39); located within a long intergenic non-coding RNA gene (AC004009.3), close to the HOXA gene cluster.ConclusionsWe uncovered germline variants on chromosome 7 at BFDP < 15% close to genes for which there is biological evidence related to breast cancer outcome. However, the paucity of variants associated with mortality at genome-wide significance underpins the challenge in providing genetic-based individualised prognostic information for breast cancer patients

A network analysis to identify mediators of germline-driven differences in breast cancer prognosis

cited By 0Identifying the underlying genetic drivers of the heritability of breast cancer prognosis remains elusive. We adapt a network-based approach to handle underpowered complex datasets to provide new insights into the potential function of germline variants in breast cancer prognosis. This network-based analysis studies similar to 7.3 million variants in 84,457 breast cancer patients in relation to breast cancer survival and confirms the results on 12,381 independent patients. Aggregating the prognostic effects of genetic variants across multiple genes, we identify four gene modules associated with survival in estrogen receptor (ER)-negative and one in ER-positive disease. The modules show biological enrichment for cancer-related processes such as G-alpha signaling, circadian clock, angiogenesis, and Rho-GTPases in apoptosis.Peer reviewe