916 research outputs found
Detecting paired and counterflow superfluidity via dipole oscillations
We suggest an experimentally feasible procedure to observe paired and
counterflow superfluidity in ultra-cold atom systems. We study the time
evolution of one-dimensional mixtures of bosonic atoms in an optical lattice
following an abrupt displacement of an additional weak confining potential. We
find that the dynamic responses of the paired superfluid phase for attractive
inter-species interactions and the counterflow superfluid phase for repulsive
interactions are qualitatively distinct and reflect the quasi long-range order
that characterizes these states. These findings suggest a clear experimental
procedure to detect these phases, and give an intuitive insight into their
dynamics.Comment: 4 pages,5 figure
Alignment and clustering of phylogenetic markers - implications for microbial diversity studies
<p>Abstract</p> <p>Background</p> <p>Molecular studies of microbial diversity have provided many insights into the bacterial communities inhabiting the human body and the environment. A common first step in such studies is a survey of conserved marker genes (primarily 16S rRNA) to characterize the taxonomic composition and diversity of these communities. To date, however, there exists significant variability in analysis methods employed in these studies.</p> <p>Results</p> <p>Here we provide a critical assessment of current analysis methodologies that cluster sequences into operational taxonomic units (OTUs) and demonstrate that small changes in algorithm parameters can lead to significantly varying results. Our analysis provides strong evidence that the species-level diversity estimates produced using common OTU methodologies are inflated due to overly stringent parameter choices. We further describe an example of how semi-supervised clustering can produce OTUs that are more robust to changes in algorithm parameters.</p> <p>Conclusions</p> <p>Our results highlight the need for systematic and open evaluation of data analysis methodologies, especially as targeted 16S rRNA diversity studies are increasingly relying on high-throughput sequencing technologies. All data and results from our study are available through the JGI FAMeS website <url>http://fames.jgi-psf.org/</url>.</p
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Variable responses of human and non-human primate gut microbiomes to a Western diet
BACKGROUND: The human gut microbiota interacts closely with human diet and physiology. To better understand the mechanisms behind this relationship, gut microbiome research relies on complementing human studies with manipulations of animal models, including non-human primates. However, due to unique aspects of human diet and physiology, it is likely that host-gut microbe interactions operate differently in humans and non-human primates. RESULTS: Here, we show that the human microbiome reacts differently to a high-protein, high-fat Western diet than that of a model primate, the African green monkey, or vervet (Chlorocebus aethiops sabaeus). Specifically, humans exhibit increased relative abundance of Firmicutes and reduced relative abundance of Prevotella on a Western diet while vervets show the opposite pattern. Predictive metagenomics demonstrate an increased relative abundance of genes associated with carbohydrate metabolism in the microbiome of only humans consuming a Western diet. CONCLUSIONS: These results suggest that the human gut microbiota has unique properties that are a result of changes in human diet and physiology across evolution or that may have contributed to the evolution of human physiology. Therefore, the role of animal models for understanding the relationship between the human gut microbiota and host metabolism must be re-focused.P40 OD010965 - NIH HHS; P40 RR019963 - NCRR NIH HHS; P51 OD011132 - NIH HHS; R01 RR016300 - NCRR NIH HHS; 5R01RR016300 - NCRR NIH HH
A Multi-Epoch HST Study of the Herbig-Haro Flow from XZ Tauri
We present nine epochs of Hubble Space Telescope optical imaging of the
bipolar outflow from the pre-main sequence binary XZ Tauri. Our data monitors
the system from 1995-2005 and includes emission line images of the flow. The
northern lobe appears to be a succession of bubbles, the outermost of which
expanded ballistically from 1995-1999 but in 2000 began to deform and
decelerate along its forward edge. It reached an extent of 6" from the binary
in 2005. A larger and fainter southern counterbubble was detected for the first
time in deep ACS images from 2004. Traces of shocked emission are seen as far
as 20" south of the binary. The bubble emission nebulosity has a low excitation
overall, as traced by the [S II]/H-alpha line ratio, requiring a nearly
comoving surrounding medium that has been accelerated by previous ejections or
stellar winds.
Within the broad bubbles there are compact emission knots whose alignments
and proper motions indicate that collimated jets are ejected from each binary
component. The jet from the southern component, XZ Tau A, is aligned with the
outflow axis of the bubbles and has tangential knot velocities of 70-200 km/s.
Knots in the northern flow are seen to slow and brighten as they approach the
forward edge of the outermost bubble. The knots in the jet from the other star,
XZ Tau B, have lower velocities of ~100 km/s
Al2Mo3O12/polyethylene composites with reduced coefficient of thermal expansion
Recently, polymer composites reinforced with low fractions of thermomiotic nanoceramics have triggered a lot of research. The efforts have been focused on achieving considerable reduction of the coefficient of thermal expansion (CTE) of polymeric materials without deterioration of other physical properties. In this context, polyethylene (PE) composites reinforced with different loads of Al2Mo3O12 nanofillers (0.5â4 mass %) were fabricated by micro-compounding. To enhance the interfacial interaction between the two components, chemical functionalization of Al2Mo3O12 was performed with vinyltrimethoxysilane (VTMS) prior to micro-compounding. Infrared spectroscopy and thermogravimetry demonstrated the successful grafting of VTMS on the Al2Mo3O12 surface. The composites showed strongly decreased CTEs, up to 46 % reduction for loadings of 4 mass % compared with neat PE, suggesting intimate fillerâmatrix interactions. The variation of CTEs of the composites in terms of the filler fraction was successfully described by Turnerâs model allowing calculation of the bulk modulus of monoclinic Al2Mo3O12 (13.6 ± 2.6 GPa), in agreement with the value obtained by an ultrasonic method. The thermal stability of the composites was improved, although the addition of functionalized fillers decreased the degree of crystallinity of the PE to a small extent. The Youngâs modulus and yield strength of the composites increased from 6.6 to 19.1 % and 4.0â6.0 %, respectively, supporting the existence of strong fillerâmatrix interactions, contributing to an efficient load transfer. Finite element analysis of thermal stresses indicated absence of plastic deformation of the matrix or fracture of the nanofillers, for a 100 K temperature drop
Towards an Understanding of the Globular Cluster Over--abundance around the Central Giant Elliptical NGC 1399
We investigate the kinematics of a combined sample of 74 globular clusters
around NGC 1399. Their high velocity dispersion, increasing with radius,
supports their association with the gravitational potential of the galaxy
cluster rather than with that of NGC 1399 itself. We find no evidence for
rotation in the full sample, although some indication for rotation in the outer
regions. The data do not allow us to detect differences between the kinematics
of the blue and red sub-populations of globular clusters.
A comparison between the globular cluster systems of NGC 1399 and those of
NGC 1404 and NGC 1380 indicates that the globular clusters in all three
galaxies are likely to have formed via similar mechanisms and at similar
epochs. The only property which distinguishes the NGC 1399 globular cluster
system from these others is that it is ten times more abundant. We summarize
the evidence for associating these excess globulars with the galaxy cluster
rather than with NGC 1399 itself, and suggest that the over-abundance can be
explained by tidal stripping, at an early epoch, of neighboring galaxies and
subsequent accumulation of globulars in the gravitational potential of the
galaxy cluster.Comment: AJ accepted (March issue), 27 pages (6 figures included), AAS style,
two columns. Also available at http://www.eso.org/~mkissle
"Why should I believe this?" Deciphering the qualities of credible online customer reviews
Online customer reviews have been shown to have a powerful impact on the sales of a given product or service. However, the qualities of a âcredibleâ online customer review are still subject to debate. Existing research has highlighted the potential influence of a range of factors on the credibility of an online customer review, but relies heavily on quantitative methods and a âtop downâ approach. In turn, this can reduce our understanding of the influence of these factors into merely discerning whether one pre-determined factor is more influential than another is. This paper adopted a âbottom upâ thematic analysis of individual qualitative interviews with a purposeful sample of consumers who regularly utilised online customer reviews. The findings uncovered a range of factors that influenced the credibility of an online customer review that were attached to a readerâs personal experience and to the content of a specific review, and inferred the existence of a reciprocal relationship between the constructs of review helpfulness and review credibility
Sea-level rise and archaeological site destruction: An example from the southeastern United States using DINAA (Digital Index of North American Archaeology)
The impact of changing climate on terrestrial and underwater archaeological sites, historic buildings, and cultural landscapes can be examined through quantitatively-based analyses encompassing large data samples and broad geographic and temporal scales. The Digital Index of North American Archaeology (DINAA) is a multi-institutional collaboration that allows researchers online access to linked heritage data from multiple sources and data sets. The effects of sea-level rise and concomitant human population relocation is examined using a sample from nine states encompassing much of the Gulf and Atlantic coasts of the southeastern United States. A 1 m rise in sea-level will result in the loss of over \u3e13,000 recorded historic and prehistoric archaeological sites, as well as over 1000 locations currently eligible for inclusion on the National Register of Historic Places (NRHP), encompassing archaeological sites, standing structures, and other cultural properties. These numbers increase substantially with each additional 1 m rise in sea level, with \u3e32,000 archaeological sites and \u3e2400 NRHP properties lost should a 5 m rise occur. Many more unrecorded archaeological and historic sites will also be lost as large areas of the landscape are flooded. The displacement of millions of people due to rising seas will cause additional impacts where these populations resettle. Sea level rise will thus result in the loss of much of the record of human habitation of the coastal margin in the Southeast within the next one to two centuries, and the numbers indicate the magnitude of the impact on the archaeological record globally. Construction of large linked data sets is essential to developing procedures for sampling, triage, and mitigation of these impacts
Rebirth of a nation or 'The incomparable toothbrush': the origin story and narrative regeneration in Sri Lanka
I examine the post-Independence role of Sri Lankaâs origin story, revealing the ways in which the foundational myth of the Mahavamsa functions as a conflicted site of cultural âencompassmentâ (Kapferer) in literary and political discourse. Through an analysis of the fiction of Tissa Abeysekara, Carl Muller and the assassinated president Ranasinghe Premadasa, I show how the scripting of this myth in fiction reveals a shift from the celebratory drives of nationalism to a critique of patriotism in a way that both reflects and anticipates a broader paradigmatic shift in the construction of belonging and the outsider found in post-war Sri Lanka
Uncovering treatment burden as a key concept for stroke care: a systematic review of qualitative research
<b>Background</b> Patients with chronic disease may experience complicated management plans requiring significant personal investment. This has been termed âtreatment burdenâ and has been associated with unfavourable outcomes. The aim of this systematic review is to examine the qualitative literature on treatment burden in stroke from the patient perspective.<p></p>
<b>Methods and findings</b> The search strategy centred on: stroke, treatment burden, patient experience, and qualitative methods. We searched: Scopus, CINAHL, Embase, Medline, and PsycINFO. We tracked references, footnotes, and citations. Restrictions included: English language, date of publication January 2000 until February 2013. Two reviewers independently carried out the following: paper screening, data extraction, and data analysis. Data were analysed using framework synthesis, as informed by Normalization Process Theory. Sixty-nine papers were included. Treatment burden includes: (1) making sense of stroke management and planning care, (2) interacting with others, (3) enacting management strategies, and (4) reflecting on management. Health care is fragmented, with poor communication between patient and health care providers. Patients report inadequate information provision. Inpatient care is unsatisfactory, with a perceived lack of empathy from professionals and a shortage of stimulating activities on the ward. Discharge services are poorly coordinated, and accessing health and social care in the community is difficult. The study has potential limitations because it was restricted to studies published in English only and data from low-income countries were scarce.<p></p>
<b>Conclusions</b> Stroke management is extremely demanding for patients, and treatment burden is influenced by micro and macro organisation of health services. Knowledge deficits mean patients are ill equipped to organise their care and develop coping strategies, making adherence less likely. There is a need to transform the approach to care provision so that services are configured to prioritise patient needs rather than those of health care systems
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