340 research outputs found

    The Threat of Capital Drain: A Rationale for Public Banks?

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    This paper yields a rationale for why subsidized public banks may be desirable from a regional perspective in a financially integrated economy. We present a model with credit rationing and heterogeneous regions in which public banks prevent a capital drain from poorer to richer regions by subsidizing local depositors, for example, through a public guarantee. Under some conditions, cooperative banks can perform the same function without any subsidization; however, they may be crowded out by public banks. We also discuss the impact of the political structure on the emergence of public banks in a political-economy setting and the role of interregional mobility

    Observed 1970-2005 cooling of summer daytime temperatures in coastal California

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    This study evaluated 1950–2005 summer [June–August (JJA)] mean monthly air temperatures for two California air basins: the South Coast Air Basin (SoCAB) and the San Francisco Bay Area (SFBA). The study focuses on the more rapid post-1970 warming period, and its daily minima temperature Tmin and maxima temperature Tmax values were used to produce average monthly values and spatial distributions of trends for each air basin. Additional analyses included concurrent SSTs, 40-yr European Centre for Medium-Range Weather Forecasts (ECMWF) Re-Analysis (ERA-40) sea level coastal pressure gradients, and GCM-downscaled average temperature Tave values. Results for all 253 California National Weather Service (NWS) Cooperative Observer Program (COOP) sites together showed increased Tave values (0.23°C decade−1); asymmetric warming, as Tmin values increase faster than Tmax values (0.27° versus 0.04°C decade−1) and thus decreased daily temperature range (DTR) values (0.15°C decade−1). The spatial distribution of observed SoCAB and SFBA Tmax values exhibited a complex pattern, with cooling (−0.30°C decade−1) in low-elevation coastal areas open to marine air penetration and warming (0.32°C decade−1) in inland areas. Results also showed that decreased DTR values in the basins arose from small increases at inland sites (0.16°C decade−1) combined with large decreases (−0.58°C decade−1) at coastal sites. It is also possible that some of the current observed temperature trends could be associated with low-frequency decadal variability, expected even with a constant radiative forcing. Previous studies suggest that cooling JJA Tmax values in coastal California were a result of increased irrigation, coastal upwelling, or cloud cover. The current hypothesis is that they arise (as a possible “reverse reaction”) from the global warming of inland areas, which results in increased sea-breeze flow activity. GCM model Tave warming decreased from 0.13°C decade−1 at inland sites to 0.08°C decade−1 in coastal areas. Sea level pressure increased in the Pacific high and decreased in the thermal low. The corresponding gradient thus showed a trend of 0.04 hPa 100 km−1 decade−1, supportive of the hypothesis of increased sea-breeze activity

    Archivi digitali d\u2019autore: ipotesi di lavoro

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    Il panel mira ad attraversare su pi\uf9 livelli il tema della conservazione del digitale nativo nell\u2019ambito degli archivi di persona, con particolare riguardo alla conservazione e gestione dei materiali di autori contemporanei. L\u2019intento \ue8 quello di avviare una riflessione condivisa con la comunit\ue0 scientifica su metodologie e strumenti da adottare in questo campo di indagine non del tutto esplorato e ancora carico di criticit\ue0 teoriche e operative. Se \ue8 chiaro ormai che la conservazione degli archivi nativi digitali \ue8 una sfida sempre pi\uf9 importante nei pi\uf9 diversi settori della nostra societ\ue0 (l\u2019ambito della pubblica amministrazione e quello forense sono tra gli esempi pi\uf9 noti), \ue8 altrettanto vero che per gli archivi di persona, nel contesto specifico della produzione letteraria, i casi di studio a nostra disposizione sono ancora sporadici e non sufficienti per individuare del tutto delle buone pratiche. Pare dunque necessario un confronto all\u2019interno della comunit\ue0 scientifica delle DH, non tanto per condividere risultati quanto per illustrare le problematiche maggiori e individuare delle ipotesi di lavoro. Il panel vuole aprirsi al dibattito con un approccio multidisciplinare, cercando di affrontare le questioni archivistiche pi\uf9 importanti relative all\u2019acquisizione e conservazione dei fondi, alla loro archiviazione, gestione e fruizione. Verr\ue0 dato particolare rilievo alla scelta di formati e standard, alla qualit\ue0 dei dati e dei servizi, ai numerosi aspetti critici sotto il profilo giuridico, alla gestione del versioning e agli strumenti per la ricerca e la didattica. Nel corso della sessione saranno esaminate due esperienze italiane: il lavoro sull\u2019archivio ibrido di Massimo Vannucci e il progetto PAD \u2013 Pavia Archivi Digitali, che ha avviato nel 2010 un percorso di sperimentazione su archivi di scrittori contemporanei, perfezionando negli anni alcune strategie per le fasi di preparazione dei conferimenti e acquisizione dei materiali

    CARB-ES-19 Multicenter Study of Carbapenemase-Producing Klebsiella pneumoniae and Escherichia coli From All Spanish Provinces Reveals Interregional Spread of High-Risk Clones Such as ST307/OXA-48 and ST512/KPC-3.

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    CARB-ES-19 is a comprehensive, multicenter, nationwide study integrating whole-genome sequencing (WGS) in the surveillance of carbapenemase-producing K. pneumoniae (CP-Kpn) and E. coli (CP-Eco) to determine their incidence, geographical distribution, phylogeny, and resistance mechanisms in Spain. Methods: In total, 71 hospitals, representing all 50 Spanish provinces, collected the first 10 isolates per hospital (February to May 2019); CPE isolates were first identified according to EUCAST (meropenem MIC > 0.12 mg/L with immunochromatography, colorimetric tests, carbapenem inactivation, or carbapenem hydrolysis with MALDI-TOF). Prevalence and incidence were calculated according to population denominators. Antibiotic susceptibility testing was performed using the microdilution method (EUCAST). All 403 isolates collected were sequenced for high-resolution single-nucleotide polymorphism (SNP) typing, core genome multilocus sequence typing (cgMLST), and resistome analysis. Results: In total, 377 (93.5%) CP-Kpn and 26 (6.5%) CP-Eco isolates were collected from 62 (87.3%) hospitals in 46 (92%) provinces. CP-Kpn was more prevalent in the blood (5.8%, 50/853) than in the urine (1.4%, 201/14,464). The cumulative incidence for both CP-Kpn and CP-Eco was 0.05 per 100 admitted patients. The main carbapenemase genes identified in CP-Kpn were bla OXA-48 (263/377), bla KPC-3 (62/377), bla VIM-1 (28/377), and bla NDM-1 (12/377). All isolates were susceptible to at least two antibiotics. Interregional dissemination of eight high-risk CP-Kpn clones was detected, mainly ST307/OXA-48 (16.4%), ST11/OXA-48 (16.4%), and ST512-ST258/KPC (13.8%). ST512/KPC and ST15/OXA-48 were the most frequent bacteremia-causative clones. The average number of acquired resistance genes was higher in CP-Kpn (7.9) than in CP-Eco (5.5). Conclusion: This study serves as a first step toward WGS integration in the surveillance of carbapenemase-producing Enterobacterales in Spain. We detected important epidemiological changes, including increased CP-Kpn and CP-Eco prevalence and incidence compared to previous studies, wide interregional dissemination, and increased dissemination of high-risk clones, such as ST307/OXA-48 and ST512/KPC-3
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