The influence of nova nucleosynthesis on the chemical evolution of the Galaxy

We adopt up-to-date yields of 7Li, 13C, 15N from classical novae and use a well tested model for the chemical evolution of the Milky Way in order to predict the temporal evolution of these elemental species in the solar neighborhood. In spite of major uncertainties due to our lack of knowledge of metallicity effects on the final products of explosive nucleosynthesis in nova outbursts, we find a satisfactory agreement between theoretical predictions and observations for 7Li and 13C. On the contrary, 15N turns out to be overproduced by about an order of magnitude.Comment: 8 pages, latex, 3 figures. To appear in "The Chemical Evolution of the Milky Way: Stars versus Clusters", eds. F. Giovannelli and F. Matteucci (Kluwer: Dordrecht

The ESO UVES Advanced Data Products Quasar Sample: Neutral Gas Mass and Metal Abundances in the Universe

Damped Lyα absorbers (DLAs), seen in the spectra of background quasars, are unique probes to select HI-rich galaxies. We selected a dataset of 250 quasars observed with the Ultraviolet Visual Echelle Spectrograph (UVES) and available through the ESO UVES Advanced Data Products (EUADP) archive, to study the gas and metal properties of 150 damped absorbers. These high-redshift absorbers contain information on the physical state and chemical composition of the interstellar medium and the neutral gas mass, a possible indicator of gas consumption as star formation proceeds. We find no evolution of the neutral gas mass density, with sub-DLAs contributing 8-20% (increasing with redshift). The EUADP dataset provides insights into the nucleosynthetic origin of nitrogen, confirming the bimodal behaviour of [N/α], and also confirms the deficiency of argon in DLAs. <P /

Early stages of Nitrogen enrichment in galaxies: Clues from measurements in damped Lyman alpha systems

We present 4 new measurements of nitrogen abundances and one upper limit in damped Lyman alpha absorbers (DLAs) obtained by means of high resolution (FWHM \~ 7 km/s) UVES/VLT spectra. In addition to these measurements we have compiled data from all DLAs with measurements of nitrogen and alpha-capture elements (O, S or Si) available in the literature, including all HIRES/Keck and UVES/VLT data for a total of 33 systems, i.e. the largest sample investigated so far. We find that [N/alpha] ratios are distributed in two groups: 75% of the DLAs show a mean value of [N/alpha] = -0.87 with a scatter of 0.16 dex, while the remaining 25% shows ratios clustered at [N/alpha] = -1.45 with an even lower dispersion of 0.05 dex. The high [N/alpha] plateau is consistent with the one observed in metal-poor HII regions of blue compact dwarf (BCD) galaxies ([N/alpha] = -0.73 +/- 0.13), while the [N/alpha] ~ -1.5 values are the lowest ever observed in any astrophysical site. These low [N/alpha] ratios are real and not due to ionization effects. They provide a crucial evidence against the primary production of N by massive stars as responsible for the plateau at -0.9/-0.7 dex observed in DLAs and BCD galaxies. The transition between the low-N ([N/alpha] ~ -1.5) and high-N ([N/alpha] ~ -0.9) DLAs occurs at a nitrogen abundance of [N/H] ~ -2.8, suggesting that the separation may result from some peculiarity of the nitrogen enrichment history. The [N/alpha] ~ -1.5 values and their low dispersion are consistent with a modest production of primary N in massive stars; however, due to the limited sample, specially for the low-N DLAs, we cannot exclude a primary origin in intermediate mass stars as responsible for the low N abundances observed.Comment: Accepted by A&A. 25 pages, including 9 tables and 10 figure

First Stars XIV. Sulfur abundances in extremely metal-poor (EMP) stars

Sulfur is important: the site of its formation is uncertain, and at very low metallicity the trend of [S/Fe] against [Fe/H] is controversial. Below [Fe/H]=-2.0, [S/Fe] remains constant or it decreases with [Fe/H], depending on the author and the multiplet used in the analysis. Moreover, although sulfur is not significantly bound in dust grains in the ISM, it seems to behave differently in DLAs and in old metal-poor stars. We aim to determine precise S abundance in a sample of extremely metal-poor stars taking into account NLTE and 3D effects. NLTE profiles of the lines of the multiplet 1 of SI have been computed using a new model atom for S. We find sulfur in EMP stars to behave like the other alpha-elements, with [S/Fe] remaining approximately constant for [Fe/H]<-3. However, [S/Mg] seems to decrease slightly as a function of [Mg/H]. The overall abundance patterns of O, Na, Mg, Al, S, and K are best matched by the SN model yields by Heger & Woosley. The [S/Zn] ratio in EMP stars is solar, as found also in DLAs. We obtain an upper limit on the abundance of sulfur, [S/Fe] < +0.5, for the ultra metal-poor star CS 22949-037. This, along with a previous reported measurement of zinc, argues against the conjecture that the light-element abundances pattern in this star, and, by analogy, the hyper metal-poor stars HE 0107-5240 and HE 1327-2326, are due to dust depletion.Comment: 10 pages, accepted for publication in A&

Clues to the nature of damped Lyman alpha systems from chemical evolution models

The evolution of the metallicity of damped Lyman alpha systems (DLAs) is investigated in order to understand the nature of these systems. The observational data on chemical abundances of DLAs are analysed with robust statistical methods, and the abundances are corrected for dust depletion. The results of this analysis are compared to predictions of several classes of chemical evolution models: one-zone dwarf galaxy models, multizone disk models, and chemodynamical models representing dwarf galaxies. We compare the observational data on the [alpha/Fe] and [N/alpha] ratios to the predictions from the models. In DLAs, these ratios are only partially reproduced by the dwarf galaxy one-zone model and by the disk model. On the other hand, the chemodynamical model for dwarf galaxies reproduces the properties of nearly all DLAs. We derive the formation epoch of dwarf galaxies, and we find that dwarf galaxies make a significant contribution to the total neutral gas density in DLAs, and that this contribution is more important at high redshifts (z > 2-3). We propose a scenario in which the DLA population is dominated by dwarf galaxies at high redshifts and by disks at lower redshifts. We also find that Lyman Break Galaxies (LBGs) may constitute a sequence rather than present a sharp dichotomy between the two populations. We also arise the possibility that we could be missing a whole population of high HI density column objects, with metallicities intermediate between those of DLAs and LBGs. Finally, we discuss the possibility that relying only on the observations of DLAs could lead to an underestimate of the metal content of the high redshift Universe.Comment: 23 pages, 19 figures. Accepted for publication in MNRA

Spectral shape of the UV ionizing background and OVI absorbers at z ~ 1.5 towards HS0747+4259

We report on high resolution spectra of the bright QSO HS0747+4259 (zem = 1.90, V = 15.8) observed to search for intermediate redshift OVI absorption systems. The spectra were obtained by means of the Space Telescope Imaging Spectrograph (STIS) at the Hubble Space Telescope (HST) and the High Resolution Echelle Spectrometer (HIRES) at the W. M. Keck telescope. We identify 16 OVI systems in the range 1.07 <= z <= 1.87. Among them, six systems with zabs = 1.46-1.8 exhibit a sufficient number of lines of different ionic transitions to estimate the shape of the ionizing radiation field in the range 1 Ryd < E < 10 Ryd. All recovered UV ionizing spectra are characterized by the enhanced intensity at E > 3 Ryd compared to the model spectrum of Haardt and Madau (1996). This is in line with the observational evidence of a deficiency of strong Ly-alpha absorbers with N(HI) > 10^{15} cm^{-2}, at z < 2. The UV background shows significant local variations: the spectral shape estimated at z = 1.59 differs from that obtained at z = 1.81 and 1.73. A possible cause of these variations is the presence of a QSO/AGN at z ~= 1.54-1.59 close to the line of sight. No features favoring the input of stellar radiation to the ionizing background are detected, limiting the escape fraction of the galactic UV photons to f_esc < 0.05.Comment: 14 pages, 7 figures, 5 tables; accepted for publication in A&

Heavy elements abundances in turn-off stars and early subgiants in NGC 6752

High resolution spectra (R > 40 000) for 9 main sequence turn-off stars and 9 subgiants in the globular cluster NGC 6752 were acquired with UVES on the VLT-Kueyen (UT2). These data have been used to determine the abundances of some heavy elements (strontium, yttrium, barium and europium). This paper presents for the first time accurate results for heavy elements in this globular cluster. We did not find any systematic effect between the abundances found in turn-off stars, subgiants, and giants. We obtain the following mean abundances for these elements in our sample (turn-off stars and subgiants): [Sr/Fe] = 0.06 +/- 0.16, [Y/Fe] = -0.01 +/- 0.12, [Ba/Fe] = 0.18 +/- 0.11, and [Eu/Fe] = 0.41 +/- 0.09. The dispersion in the abundance ratios of the different elements is low and can be totally explained by uncertainties in their derivation. These ratios are in agreement with the values found in field halo stars with the same metallicity. We did not observe any correlation between the [n-capture/Fe] ratios and the star-to-star variations of the O and Na abundances. The [Ba/Eu] and [Sr/Ba] ratios show clearly that this globular cluster has also been uniformly enriched by r- and s-process synthesis.Comment: 10 pages, 8 figures. Accepted for publication in A&

Current and prospective pharmacological targets in relation to antimigraine action

Migraine is a recurrent incapacitating neurovascular disorder characterized by unilateral and throbbing headaches associated with photophobia, phonophobia, nausea, and vomiting. Current specific drugs used in the acute treatment of migraine interact with vascular receptors, a fact that has raised concerns about their cardiovascular safety. In the past, α-adrenoceptor agonists (ergotamine, dihydroergotamine, isometheptene) were used. The last two decades have witnessed the advent of 5-HT1B/1D receptor agonists (sumatriptan and second-generation triptans), which have a well-established efficacy in the acute treatment of migraine. Moreover, current prophylactic treatments of migraine include 5-HT2 receptor antagonists, Ca2+ channel blockers, and β-adrenoceptor antagonists. Despite the progress in migraine research and in view of its complex etiology, this disease still remains underdiagnosed, and available therapies are underused. In this review, we have discussed pharmacological targets in migraine, with special emphasis on compounds acting on 5-HT (5-HT1-7), adrenergic (α1, α2, and β), calcitonin gene-related peptide (CGRP 1 and CGRP2), adenosine (A1, A2, and A3), glutamate (NMDA, AMPA, kainate, and metabotropic), dopamine, endothelin, and female hormone (estrogen and progesterone) receptors. In addition, we have considered some other targets, including gamma-aminobutyric acid, angiotensin, bradykinin, histamine, and ionotropic receptors, in relation to antimigraine therapy. Finally, the cardiovascular safety of current and prospective antimigraine therapies is touched upon

Varying constants, Gravitation and Cosmology

Fundamental constants are a cornerstone of our physical laws. Any constant varying in space and/or time would reflect the existence of an almost massless field that couples to matter. This will induce a violation of the universality of free fall. It is thus of utmost importance for our understanding of gravity and of the domain of validity of general relativity to test for their constancy. We thus detail the relations between the constants, the tests of the local position invariance and of the universality of free fall. We then review the main experimental and observational constraints that have been obtained from atomic clocks, the Oklo phenomenon, Solar system observations, meteorites dating, quasar absorption spectra, stellar physics, pulsar timing, the cosmic microwave background and big bang nucleosynthesis. At each step we describe the basics of each system, its dependence with respect to the constants, the known systematic effects and the most recent constraints that have been obtained. We then describe the main theoretical frameworks in which the low-energy constants may actually be varying and we focus on the unification mechanisms and the relations between the variation of different constants. To finish, we discuss the more speculative possibility of understanding their numerical values and the apparent fine-tuning that they confront us with.Comment: 145 pages, 10 figures, Review for Living Reviews in Relativit