104 research outputs found
Acute life-threatening extrinsic allergic alveolitis in a paint controller
Background Occupational diisocyanate-induced extrinsic allergic alveolitis (EAA) is a rare and probably underestimated diagnosis. Two acute occupational EAA cases have been described in this context, but neither of them concerned hexamethylene diisocyanate (HDI) exposure. Aims To investigate the cause of a life-threatening EAA arising at work in a healthy 30-year-old female paint quality controller. Methods Occupational medical assessment, workplace evaluation, airborne and biological monitoring and immunodermatological tests. Results Diagnosis of EAA relied on congruent clinical and radiological information, confirmed occupational HDI exposure and positive IgG antibodies and patch tests. The patient worked in a small laboratory for 7 years, only occasionally using HDI-containing hardeners. While working with HDI for 6 h, she developed breathlessness, rapidly progressing to severe respiratory failure. Workplace HDI airborne exposure values ranged from undetectable levels to 4.25 p.p.b. Biological monitoring of urinary hexamethylene diamine in co-workers ranged from <1.0 to 15.4 μg/g creatinine. Patch tests 8 months later showed delayed skin reaction to HDI at 48 h. Subsequent skin biopsy showed spongiotic dermatitis with infiltration of CD4+ and CD8+ T cells. Conclusions We believe this is the first reported case of acute life-threatening EAA following exposure to HDI. Low concentrations of airborne HDI and relatively high urinary hexamethylene diamine suggest significant skin absorption of HDI could have significantly contributed to the development of this acute occupational EA
The EMPIRE Survey: Systematic Variations in the Dense Gas Fraction and Star Formation Efficiency from Full-Disk Mapping of M51
We present the first results from the EMPIRE survey, an IRAM large program
that is mapping tracers of high density molecular gas across the disks of nine
nearby star-forming galaxies. Here, we present new maps of the 3-mm transitions
of HCN, HCO+, and HNC across the whole disk of our pilot target, M51. As
expected, dense gas correlates with tracers of recent star formation, filling
the "luminosity gap" between Galactic cores and whole galaxies. In detail, we
show that both the fraction of gas that is dense, f_dense traced by HCN/CO, and
the rate at which dense gas forms stars, SFE_dense traced by IR/HCN, depend on
environment in the galaxy. The sense of the dependence is that high surface
density, high molecular gas fraction regions of the galaxy show high dense gas
fractions and low dense gas star formation efficiencies. This agrees with
recent results for individual pointings by Usero et al. 2015 but using unbiased
whole-galaxy maps. It also agrees qualitatively with the behavior observed
contrasting our own Solar Neighborhood with the central regions of the Milky
Way. The sense of the trends can be explained if the dense gas fraction tracks
interstellar pressure but star formation occurs only in regions of high density
contrast.Comment: 7 pages, 5 figures, ApJL accepte
GASP XXXIV: Unfolding the thermal side of ram pressure stripping in the jellyfish galaxy JO201
X-ray studies of jellyfish galaxies play a crucial role in understanding the
interactions between the interstellar medium (ISM) and the intracluster medium
(ICM). In this paper, we focused on the jellyfish galaxy JO201. By combining
archival Chandra observations, MUSE H cubes, and maps of the emission
fraction of the diffuse ionised gas, we investigated both its high energy
spectral properties and the spatial correlation between its X-ray and optical
emissions. The X-ray emission of JO201 is provided by both the Compton thick
AGN (L=2.710 erg s, not
corrected for intrinsic absorption) and an extended component
(L1.9-4.510 erg
s) produced by a warm plasma (kT1 keV), whose luminosity is
higher than expected from the observed star formation
(L3.8 erg s). The spectral analysis
showed that the X-ray emission is consistent with the thermal cooling of hot
plasma. These properties are similar to the ones found in other jellyfish
galaxies showing extended X-ray emission. A point-to-point analysis revealed
that this X-ray emission closely follows the ISM distribution, whereas CLOUDY
simulations proved that the ionisation triggered by this warm plasma would be
able to reproduce the [OI]/H excess observed in JO201. We conclude that
the galactic X-ray emitting plasma is originated on the surface of the ISM as a
result of the ICM-ISM interplay. This process would entail the cooling and
accretion of the ICM onto the galaxy, which could additionally fuel the star
formation, and the emergence of [OI]/H excess in the optical spectrum.Comment: 21 pages, 6 figures, 5 tables. Manuscript in press in Ap
GASP XXXIV: Unfolding the thermal side of ram pressure stripping in the jellyfish galaxy JO201
X-ray studies of jellyfish galaxies play a crucial role in understanding the interactions between the interstellar medium (ISM) and the intracluster medium (ICM). In this paper, we focused on the jellyfish galaxy JO201. By combining archival Chandra observations, Multi Unit Spectroscopic Explorer Hα cubes, and maps of the emission fraction of the diffuse ionized gas, we investigated both its high-energy spectral properties and the spatial correlation between its X-ray and optical emissions. The X-ray emission of JO201 is provided by both the Compton-thick active galactic nucleus (L0.5X-10keV = 2.7 · 1041 erg s−1, not corrected for intrinsic absorption) and an extended component (L0.5X–10 keV » 1.9–4.5 · 1041 erg s−1) produced by a warm plasma (kT»1 keV), whose luminosity is higher than expected from the observed star formation (LX ~ 3.8 · 1040erg s−1). The spectral analysis showed that the X-ray emission is consistent with the thermal cooling of hot plasma. These properties are similar to the ones found in other jellyfish galaxies showing extended X-ray emission. A point-to-point analysis revealed that this X-ray emission closely follows the ISM distribution, whereas CLOUDY simulations proved that the ionization triggered by this warm plasma would be able to reproduce the [O I]/Hα excess observed in JO201. We conclude that the galactic X-ray emitting plasma originates on the surface of the ISM as a result of the ICM–ISM interplay. This process would entail the cooling and accretion of the ICM onto the galaxy, which could additionally fuel the star formation, and the emergence of [O I]/Hα excess in the optical spectrum
MOKA3D: An innovative approach to 3D gas kinematic modelling. I. Application to AGN ionized outflows
Studying the feedback process of Active Galactic Nuclei (AGN) requires
characterising multiple kinematical components, such as rotating gas and
stellar disks, outflows, inflows, and jets. To compare the observed properties
with theoretical predictions of galaxy evolution and feedback models and to
assess the mutual interaction and energy injection rate into the interstellar
medium (ISM), one usually relies on simplified kinematic models. These models
have several limitations, as they often do not take into account projection
effects, beam smearing and the surface brightness distribution of the emitting
medium. Here, we present MOKA3D, an innovative approach to model the 3D gas
kinematics from integral field spectroscopy observations. In this first paper,
we discuss its application to the case of AGN ionised outflows, whose observed
clumpy emission and apparently irregular kinematics are only marginally
accounted for by existing kinematical models. Unlike previous works, our model
does not assume the surface brightness distribution of the gas, but exploits a
novel procedure to derive it from the observations by reconstructing the 3D
distribution of emitting clouds and providing accurate estimates of the
spatially resolved outflow physical properties (e.g. mass rate, kinetic
energy). As an example, we demonstrate the capabilities of our method by
applying it to three nearby Seyfert-II galaxies observed with MUSE at the VLT
and selected from the MAGNUM survey, showing that the complex kinematic
features observed can be described by a conical outflow with a constant radial
velocity field and a clumpy distribution of clouds.Comment: 17 pages, 14 figure
Sublittoral soft bottom communities and diversity of Mejillones Bay in northern Chile (Humboldt Current upwelling system)
The macrozoobenthos of Mejillones Bay (23°S; Humboldt Current) was quantitatively investigated over a 7-year period from austral summer 1995/1996 to winter 2002. About 78 van Veen grab samples taken at six stations (5, 10, 20 m depth) provided the basis for the analysis of the distribution of 60 species and 28 families of benthic invertebrates, as well as of their abundance and biomass. Mean abundance (2,119 individuals m-2) was in the same order compared to a previous investigation; mean biomass (966 g formalin wet mass m-2), however, exceeded prior estimations mainly due to the dominance of the bivalve Aulacomya ater. About 43% of the taxa inhabited the complete depth range. Mean taxonomic Shannon diversity (H', Log e) was 1.54 ± 0.58 with a maximum at 20 m (1.95 ± 0.33); evenness increased with depth. The fauna was numerically dominated by carnivorous gastropods, polychaetes and crustaceans (48%). About 15% of the species were suspensivorous, 13% sedimentivorous, 11% detritivorous, 7% omnivorous and 6% herbivorous. Cluster analyses showed a significant difference between the shallow and the deeper stations. Gammarid amphipods and the polychaete family Nephtyidae characterized the 5-mzone, the molluscs Aulacomya ater, Mitrella unifasciata and gammarids the intermediate zone, while the gastropod Nassarius gayi and the polychaete family Nereidae were most prominent at the deeper stations. The communities of the three depth zones did not appear to be limited by hypoxia during non-El Niño conditions. Therefore, no typical change in community structure occurred during El Niño 1997–1998, in contrast to what was observed for deeper faunal assemblages and hypoxic bays elsewhere in the coastal Humboldt Current system
(Sub)millimetre interferometric imaging of a sample of COSMOS/AzTEC submillimetre galaxies
We investigate the environment of 23 submillimetre galaxies (SMGs) drawn from a signal-to-noise (S/N)-limited sample of SMGs originally discovered in the James Clerk Maxwell Telescope (JCMT)/AzTEC 1.1 mm continuum survey of a Cosmic Evolution Survey (COSMOS) subfield and then followed up with the Submillimetre Array and Plateau de Bure Interferometer at 890 mu m and 1.3 mm, respectively. These SMGs already have well-defined multiwavelength counterparts and redshifts. We also analyse the environments of four COSMOS SMGs spectroscopically confirmed to lie at redshifts z(spec) > 4 : 5, and one at z(spec) = 2 : 49 resulting in a total SMG sample size of 28. We search for overdensities using the COSMOS photometric redshifts based on over 30 UV-NIR photometric measurements including the new UltraVISTA data release 2 and Spitzer/SPLASH data, and reaching an accuracy of sigma(Delta z/(1+z)) = (1 + z) = 0 : 0067 (0 : 0155) at z 3.5). To identify overdensities we apply the Voronoi tessellation analysis, and estimate the redshift-space overdensity estimator delta(g) as a function of distance from the SMG and/or overdensity centre. We test and validate our approach via simulations, X-ray detected groups or clusters, and spectroscopic verifications using VUDS and zCOSMOS catalogues which show that even with photometric redshifts in the COSMOS field we can e ffi ciently retrieve overdensities out to z approximate to 5. Our results yield that 11 out of 23 (48%) JCMT/AzTEC 1.1 mm SMGs occupy overdense environments. Considering the entire JCMT/AzTEC 1.1 mm S = N >= 4 sample and taking the expected fraction of spurious detections into account, this means that 35-61% of the SMGs in the S/N-limited sample occupy overdense environments. We perform an X-ray stacking analysis in the 0.5-2 keV band using a 32 '' aperture and our SMG positions, and find statistically significant detections. For our z 2 subsample yields an average flux of (1.3 +/- 0.5) x 10(-16) erg s(-1) cm(-2) and a corresponding total mass of M-200 = 2 x 10(13) M-circle dot. Our results suggest a higher occurrence of SMGs occupying overdense environments at z >= 3 than at z <3. This may be understood if highly star-forming galaxies can only be formed in the highest peaks of the density field tracing the most massive dark matter haloes at early cosmic epochs, while at later times cosmic structure may have matured su ffi ciently that more modest overdensities correspond to su ffi ciently massive haloes to form SMGs.Peer reviewe
GASP XXXVIII: The LOFAR-MeerKAT-VLA View on the Nonthermal Side of a Jellyfish Galaxy
Ram pressure stripping is a crucial evolutionary driver for cluster galaxies. It is thought to be able to accelerate the evolution of their star formation, trigger the activity of their central active galactic nucleus (AGN) and the interplay between galactic and environmental gas, and eventually dissipate their gas reservoirs. We explored the outcomes of ram pressure stripping by studying the nonthermal radio emission of the jellyfish galaxy JW100 in the cluster A2626 (z = 0.055), by combining LOw Frequency Array, MeerKAT, and Very Large Array observations from 0.144 to 5.5 GHz. We studied the integrated spectra of the stellar disk, the stripped tail, and the AGN; mapped the spectral index over the galaxy; and constrained the magnetic field intensity to between 11 and 18 μG in the disk and <10 μG in the tail. The stellar disk radio emission is dominated by a radiatively old plasma, likely related to an older phase of a high star formation rate. This suggests that the star formation was quickly quenched by a factor of 4 in a few 107 yr. The radio emission in the tail is consistent with the stripping scenario, where the radio plasma that originally accelerated in the disk is subsequently displaced in the tail. The morphology of the radio and X-ray emissions supports the scenario of the accretion of magnetized environmental plasma onto the galaxy. The AGN nonthermal spectrum indicates that relativistic electron acceleration may have occurred simultaneously with a central ionized gas outflow, thus suggesting a physical connection between the two processes
The clinical relevance of oliguria in the critically ill patient : Analysis of a large observational database
Funding Information: Marc Leone reports receiving consulting fees from Amomed and Aguettant; lecture fees from MSD, Pfizer, Octapharma, 3 M, Aspen, Orion; travel support from LFB; and grant support from PHRC IR and his institution. JLV is the Editor-in-Chief of Critical Care. The other authors declare that they have no relevant financial interests. Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Urine output is widely used as one of the criteria for the diagnosis and staging of acute renal failure, but few studies have specifically assessed the role of oliguria as a marker of acute renal failure or outcomes in general intensive care unit (ICU) patients. Using a large multinational database, we therefore evaluated the occurrence of oliguria (defined as a urine output 16 years) patients in the ICON audit who had a urine output measurement on the day of admission were included. To investigate the association between oliguria and mortality, we used a multilevel analysis. Results: Of the 8292 patients included, 2050 (24.7%) were oliguric during the first 24 h of admission. Patients with oliguria on admission who had at least one additional 24-h urine output recorded during their ICU stay (n = 1349) were divided into three groups: transient - oliguria resolved within 48 h after the admission day (n = 390 [28.9%]), prolonged - oliguria resolved > 48 h after the admission day (n = 141 [10.5%]), and permanent - oliguria persisting for the whole ICU stay or again present at the end of the ICU stay (n = 818 [60.6%]). ICU and hospital mortality rates were higher in patients with oliguria than in those without, except for patients with transient oliguria who had significantly lower mortality rates than non-oliguric patients. In multilevel analysis, the need for RRT was associated with a significantly higher risk of death (OR = 1.51 [95% CI 1.19-1.91], p = 0.001), but the presence of oliguria on admission was not (OR = 1.14 [95% CI 0.97-1.34], p = 0.103). Conclusions: Oliguria is common in ICU patients and may have a relatively benign nature if only transient. The duration of oliguria and need for RRT are associated with worse outcome.publishersversionPeer reviewe
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