Effect of stellar flares on the upper atmospheres of HD 189733b and HD 209458b

Stellar flares are a frequent occurrence on young low-mass stars around which many detected exoplanets orbit. Flares are energetic, impulsive events, and their impact on exoplanetary atmospheres needs to be taken into account when interpreting transit observations. We have developed a model to describe the upper atmosphere of Extrasolar Giant Planets (EGPs) orbiting flaring stars. The model simulates thermal escape from the upper atmospheres of close-in EGPs. Ionisation by solar radiation and electron impact is included and photochemical and diffusive transport processes are simulated. This model is used to study the effect of stellar flares from the solar-like G star HD209458 and the young K star HD189733 on their respective planets. A hypothetical HD209458b-like planet orbiting the active M star AU Mic is also simulated. We find that the neutral upper atmosphere of EGPs is not significantly affected by typical flares. Therefore, stellar flares alone would not cause large enough changes in planetary mass loss to explain the variations in HD189733b transit depth seen in previous studies, although we show that it may be possible that an extreme stellar proton event could result in the required mass loss. Our simulations do however reveal an enhancement in electron number density in the ionosphere of these planets, the peak of which is located in the layer where stellar X-rays are absorbed. Electron densities are found to reach 2.2 to 3.5 times pre-flare levels and enhanced electron densities last from about 3 to 10 hours after the onset of the flare. The strength of the flare and the width of its spectral energy distribution affect the range of altitudes that see enhancements in ionisation. A large broadband continuum component in the XUV portion of the flaring spectrum in very young flare stars, such as AU Mic, results in a broad range of altitudes affected in planets orbiting this star.Comment: accepted for publication in A&

Feline hypersomatotropism and acromegaly tumorigenesis: a potential role for the AIP gene

Acromegaly in humans is usually sporadic, however up to 20% of familial isolated pituitary adenomas are caused by germline sequence variants of the aryl-hydrocarbon-receptor interacting protein (AIP) gene. Feline acromegaly has similarities to human acromegalic families with AIP mutations. The aim of this study was to sequence the feline AIP gene, identify sequence variants and compare the AIP gene sequence between feline acromegalic and control cats, and in acromegalic siblings. The feline AIP gene was amplified through PCR using whole blood genomic DNA from 10 acromegalic and 10 control cats, and 3 sibling pairs affected by acromegaly. PCR products were sequenced and compared with the published predicted feline AIP gene. A single nonsynonymous SNP was identified in exon 1 (AIP:c.9T > G) of two acromegalic cats and none of the control cats, as well as both members of one sibling pair. The region of this SNP is considered essential for the interaction of the AIP protein with its receptor. This sequence variant has not previously been reported in humans. Two additional synonymous sequence variants were identified (AIP:c.481C > T and AIP:c.826C > T). This is the first molecular study to investigate a potential genetic cause of feline acromegaly and identified a nonsynonymous AIP single nucleotide polymorphism in 20% of the acromegalic cat population evaluated, as well as in one of the sibling pairs evaluated

Estimation of the XUV radiation onto close planets and their evaporation

Context: The current distribution of planet mass vs. incident stellar X-ray flux supports the idea that photoevaporation of the atmosphere may take place in close-in planets. Integrated effects have to be accounted for. A proper calculation of the mass loss rate due to photoevaporation requires to estimate the total irradiation from the whole XUV range. Aims: The purpose of this paper is to extend the analysis of the photoevaporation in planetary atmospheres from the accessible X-rays to the mostly unobserved EUV range by using the coronal models of stars to calculate the EUV contribution to the stellar spectra. The mass evolution of planets can be traced assuming that thermal losses dominate the mass loss of their atmospheres. Methods: We determine coronal models for 82 stars with exoplanets that have X-ray observations available. Then a synthetic spectrum is produced for the whole XUV range (~1-912 {\AA}). The determination of the EUV stellar flux, calibrated with real EUV data, allows us to calculate the accumulated effects of the XUV irradiation on the planet atmosphere with time, as well as the mass evolution for planets with known density. Results: We calibrate for the first time a relation of the EUV luminosity with stellar age valid for late-type stars. In a sample of 109 exoplanets, few planets with masses larger than ~1.5 Mj receive high XUV flux, suggesting that intense photoevaporation takes place in a short period of time, as previously found in X-rays. The scenario is also consistent with the observed distribution of planet masses with density. The accumulated effects of photoevaporation over time indicate that HD 209458b may have lost 0.2 Mj since an age of 20 Myr. Conclusions: Coronal radiation produces rapid photoevaporation of the atmospheres of planets close to young late-type stars. More complex models are needed to explain fully the observations.Comment: Accepted by A&A. 10 pages, 8 figures, 7 Tables (2 online). Additional online material includes 7 pages, 6 figures and 6 tables, all include

Prospective evaluation of a protocol for transitioning porcine lente insulintreated diabetic cats to human recombinant protamine zinc insulin

Objectives The objective was to evaluate a nadir-led protocol for transitioning porcine lente insulin suspension (PLIS)-treated diabetic cats onto human recombinant protamine zinc insulin (PZIR). Methods Recently diagnosed (<5 months) diabetic cats, treated with PLIS q12h for 6 weeks, were recruited. Fructosamine, 24 h blood glucose curve (BGC), quality of life assessment (DIAQoL-pet score) and Diabetic Clinical Score (DCS) were assessed at enrolment (PLIS-treated) and 2, 4 and 12 weeks after transitioning to PZIR (starting dose 0.2-0.7 U/kg q12h). Short duration of insulin action was defined as <9 h. Linear mixed effects modelling assessed for change in fructosamine, mean blood glucose (MBG) during BGCs, DIAQoL-pet score, DCS and q12h insulin dose. McNemar's tests compared the proportion of cats with hypoglycaemia at week 0 (PLIS-treated) and week 4 (PZIR-treated). Results Twenty-two cats were recruited. Median PLIS dose at enrolment was 0.5 U/kg (interquartile range 0.3-0.7 U/kg) q12h, equalling median PZIR starting dose (0.5 U/kg; interquartile range 0.3-0.7 U/kg q12h). Transitioning was followed by significant decreases in fructosamine (P = 0.00007), insulin dose (P = 0.02), DCS (P = 8.1 x 10(-8)) and DIAQoL-pet score (P = 0.003), indicating improved quality of life. MBG did not alter significantly (P = 0.1). Five cats (22.7%) achieved remission. Hypoglycaemia was recorded in 30/190 12 h BGCs (15.8%) and five cats experienced clinical hypoglycaemia. The proportion of cats with hypoglycaemia did not differ between PLIS (week 0) and PZIR (week 4) (P = 1.0). Duration of action was analysed in 19 cats. Six cats (31.6%) showed short duration of action on PLIS, compared with two cats (10.5%) after 4 weeks on PZIR. All six cats with short PLIS duration showed duration of 9 h on PZIR. Conclusions and relevance Used alongside a low-carbohydrate diet, transitioning to PZIR was associated with significantly improved clinical signs and quality of life, with some cats achieving remission. Transition to PZIR should be considered for cats with short duration of action on PLIS

The flaring and quiescent components of the solar corona

The solar corona is a template to understand stellar activity. The Sun is a moderately active star, and its corona differs from active stars: active stellar coronae have a double-peaked EM(T) with the hot peak at 8-20 MK, while the non flaring solar corona has one peak at 1-2 MK. We study the average contribution of flares to the solar EM(T) to investigate indirectly the hypothesis that the hot peak of the EM(T) of active stellar coronae is due to a large number of unresolved solar-like flares, and to infer properties on the flare distribution from nano- to macro-flares. We measure the disk-integrated time-averaged emission measure, EM_F(T), of an unbiased sample of solar flares analyzing uninterrupted GOES/XRS light curves over time intervals of one month. We obtain the EM_Q(T) of quiescent corona for the same time intervals from the Yohkoh/SXT data. To investigate how EM_F(T) and EM_Q(T) vary with the solar cycle, we evaluate them at different phases of the cycle (from Dec. 1991 to Apr. 1998). Irrespective of the solar cycle phase, EM_F(T) appears like a peak of the distribution significantly larger than the values of EM_Q(T) for T~5-10 MK. As a result the time-averaged EM(T) of the whole solar corona is double-peaked, with the hot peak, due to time-averaged flares, located at temperature similar of that of active stars, but less enhanced. The EM_F(T) shape supports the hypothesis that the hot EM(T) peak of active coronae is due to unresolved solar-like flares. If this is the case, quiescent and flare components should follow different scaling laws for increasing stellar activity. In the assumption that the heating of the corona is entirely due to flares, from nano- to macro-flares, then either the flare distribution or the confined plasma response to flares, or both, are bimodal.Comment: 8 pages, 7 postscript figures, accepted for publication in Astronomy and Astrophysic

A scenario of planet erosion by coronal radiation

Context: According to theory, high-energy emission from the coronae of cool stars can severely erode the atmospheres of orbiting planets. No observational tests of the long term effects of erosion have yet been made. Aims: To analyze the current distribution of planetary mass with X-ray irradiation of the atmospheres in order to make an observational assessment of the effects of erosion by coronal radiation. Methods: We study a large sample of planet-hosting stars with XMM-Newton, Chandra and ROSAT; make a careful identification of X-ray counterparts; and fit their spectra to make accurately measurements of the stellar X-ray flux. Results: The distribution of the planetary masses with X-ray flux suggests that erosion has taken place: most surviving massive planets, (M_p sin i >1.5 M_J), have been exposed to lower accumulated irradiation. Heavy erosion during the initial stages of stellar evolution is followed by a phase of much weaker erosion. A line dividing these two phases could be present, showing a strong dependence on planet mass. Although a larger sample will be required to establish a well-defined erosion line, the distribution found is very suggestive. Conclusions: The distribution of planetary mass with X-ray flux is consistent with a scenario in which planet atmospheres have suffered the effects of erosion by coronal X-ray and EUV emission. The erosion line is an observational constraint to models of atmospheric erosion.Comment: A&A 511, L8 (2010). 4 pages, 3 figures, 1 online table (included). Language edited; corrected a wrong unit conversion (g/s -> M_J/Gyr); corrected values in column 12 of Table 1 (slightly underestimated in first version), and Figure 2 updated accordingl

The Soft X-ray Lightcurves of Partially Eclipsed Stellar Flares

Most stellar flares' soft X-ray lightcurves possess a `typical' morphology, which consists of a rapid rise followed by a slow exponential decay. However, a study of 216 of the brightest flares on 161 pre-main sequence stars, observed during the Chandra Orion-Ultradeep Project (COUP), showed that many flare lightcurves depart from this typical morphology. While this can be attributed to the superposition of multiple typical flares, we explore the possibility that the time-variable eclipsing of flares by their host stars may also be an important factor. We assume each flare is contained within a single, uniform plasma density magnetic loop and specify the intrinsic variation of the flare's emission measure with time. We consider rotational eclipse by the star itself, but also by circumstellar discs and flare-associated prominences. Based on this simple model, we generate a set of flares similar to those observed in the COUP database. Many eclipses simply reduce the flare's maximum emission measure or decay time. We conclude therefore that eclipses often pass undetected, but usually have only a modest influence on the flare emission measure profile and hence the derived loop lengths. We show that eclipsing can easily reproduce the observed atypical flare morphologies. The number of atypical modelled flare morphologies is however much less than that found in the COUP sample. The large number of observed atypical flare morphologies, therefore, must be attributed to other processes such as multiple flaring loops.Comment: 11 pages, 9 figure

Fracturas abiertas de pelvis: seguimiento a largo plazo

Presentamos una serie de fracturas abiertas de pelvis atendidas en nuestro centro. Para su estudio hemos revisado las historias clínicas de los pacientes, evaluando los resultados por medio de entrevista telefónica. La proporción de este tipo de fracturas, especialmente grave, con respecto a todas las fracturas de pelvis ingresadas es de algo más del 2%. Con especial atención analizamos las lesiones asociadas, las complicaciones y la necesidad de transfusión. Así mismo presentamos el tratamiento efectuado. La mortalidad de nuestra serie es del 6,6%. Parece evidente la necesidad de un tratamiento agresivo, que incluya la temprana estabilización de la fractura, así como la colaboración con otros especialistas quirúrgicos.A series of open pelvis fractures were restrospectively studied using the clinical records and telephone interview. This specially severe fractures account for a 2% of all pelvis fractures admitted to our hospital. We emphasised our review on associated injuries, complications and indication for transfusion. The treatment indicated is presented. The mortality was 6,7%. It is evident the need of an aggressive treatment including early fracture stabilization with a multidisciplinary approach