Utah State University Youth Conservatory Spring Graduation

An event for all the participants in the Utah State University Youth Conservatory to perform piano pieces that they practiced and mastered in the months prior. The Utah State University Youth Conservatory accepts youth up to age 18 and provides them private lessons to develop their piano skills.https://digitalcommons.usu.edu/music_programs/1114/thumbnail.jp

Panentheism and the undoing of disenchantment

In this article I draw on historical and conceptual arguments to show, first, that disenchantment and the influential view of the relationship between science and religion to which disenchantment gives rise are rooted in the metaphysics of theism. I then introduce the alternative metaphysical position of panentheism and identify Jungian psychology as an important, if implicit, mid-twentieth-century instance of panentheistic thought. Using the example of Jungian psychology, I demonstrate how the viewpoint of panentheism undoes the implications of disenchantment for the relationship between science and religion, promoting greater opportunities for dialogue and reconciliation between science and religion. I note, however, that these closer relations may depend on understanding science and religion differently from how they are understood under disenchantment. While the original tension between science and religion is eased, another tension – between panentheistic and disenchanted understandings of science and religion – is exposed. I conclude by reflecting on some implications of this discussion for sociology

Using Location-Allocation Algorithms to Distribute Multioutlet Hydrants in Irrigation Networks Design

Location-allocation algorithms allow for situating services in an efficient way in zones where the demand is dispersed across the area. In the present work, the minisum location-allocation algorithm is used to optimize the placement multioutlet hydrants, which are needed to supply irrigation to the region. The objective function aims to minimize the total access costs of the service. Because the total number of hydrants is the same as what currently exists the results can be compared with the presented solution. The proposed model reduces the total distance run to access the service, from 16,177 m to 13,560 m (16.17%), and the objective function (proportional to the cost) by 28.95%. © 2012 American Society of Civil Engineers.González Villa, FJ.; García Prats, A. (2011). Using Location-Allocation Algorithms to Distribute Multioutlet Hydrants in Irrigation Networks Design. Journal of Irrigation and Drainage Engineering. 274-283. doi:10.1061/(ASCE)IR.1943-4774.0000405S27428

An FPGA-based track finder for the L1 trigger of the CMS experiment at the high luminosity LHC

A new tracking system is under development for operation in the CMS experiment at the High Luminosity LHC. It includes an outer tracker which will construct stubs, built by correlating clusters in two closely spaced sensor layers for the rejection of hits from low transverse momentum tracks, and transmit them off-detector at 40 MHz. If tracker data is to contribute to keeping the Level-1 trigger rate at around 750 kHz under increased luminosity, a crucial component of the upgrade will be the ability to identify tracks with transverse momentum above 3 GeV/c by building tracks out of stubs. A concept for an FPGA-based track finder using a fully time-multiplexed architecture is presented, where track candidates are identified using a projective binning algorithm based on the Hough Transform. A hardware system based on the MP7 MicroTCA processing card has been assembled, demonstrating a realistic slice of the track finder in order to help gauge the performance and requirements for a full system. This paper outlines the system architecture and algorithms employed, highlighting some of the first results from the hardware demonstrator and discusses the prospects and performance of the completed track finder

Emulation of a prototype FPGA track finder for the CMS Phase-2 upgrade with the CIDAF emulation framework

The CMS collaboration is preparing a major upgrade of its detector, so it can operate during the high luminosity run of the LHC from 2026. The upgraded tracker electronics will reconstruct the trajectories of charged particles within a latency of a few microseconds, so that they can be used by the level-1 trigger. An emulation framework, CIDAF, has been developed to provide a reference for a proposed FPGA-based implementation of this track finder, which employs a Time-Multiplexed (TM) technique for data processing.The research leading to these results has received funding from the People Programme (Marie Curie Actions) of the European Unions Seventh Framework Programme FP7/2007- 2013/ under REA grant agreement n [317446] INFIERI “Intelligent Fast Interconnected and Efficient Devices for Frontier Exploitation in Research and Industry”. This work was supported in part by the the UK Science and Technology Facilities Council, we gratefully acknowledge their support

Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk.

Common variants in the hepatocyte nuclear factor 1 homeobox B (HNF1B) gene are associated with the risk of Type II diabetes and multiple cancers. Evidence to date indicates that cancer risk may be mediated via genetic or epigenetic effects on HNF1B gene expression. We previously found single-nucleotide polymorphisms (SNPs) at the HNF1B locus to be associated with endometrial cancer, and now report extensive fine-mapping and in silico and laboratory analyses of this locus. Analysis of 1184 genotyped and imputed SNPs in 6608 Caucasian cases and 37 925 controls, and 895 Asian cases and 1968 controls, revealed the best signal of association for SNP rs11263763 (P = 8.4 × 10(-14), odds ratio = 0.86, 95% confidence interval = 0.82-0.89), located within HNF1B intron 1. Haplotype analysis and conditional analyses provide no evidence of further independent endometrial cancer risk variants at this locus. SNP rs11263763 genotype was associated with HNF1B mRNA expression but not with HNF1B methylation in endometrial tumor samples from The Cancer Genome Atlas. Genetic analyses prioritized rs11263763 and four other SNPs in high-to-moderate linkage disequilibrium as the most likely causal SNPs. Three of these SNPs map to the extended HNF1B promoter based on chromatin marks extending from the minimal promoter region. Reporter assays demonstrated that this extended region reduces activity in combination with the minimal HNF1B promoter, and that the minor alleles of rs11263763 or rs8064454 are associated with decreased HNF1B promoter activity. Our findings provide evidence for a single signal associated with endometrial cancer risk at the HNF1B locus, and that risk is likely mediated via altered HNF1B gene expression