Manx traditional songs, rhymes and chants in the repertoire of the last native Manx speakers

The following collection of Manx traditional songs and song-fragments derives from a series of scientific surveys on obsolescence in Manx Gaelic from native Manx speakers undertaken in Man between the years 1886 and 1972. These surveys involved the gathering of linguistic material, whether through phonetic notation of textual readings or questioning, formal questionnaires, and / or sound-recordings, in order to enable a phonological and morphological assessment of the state of Manx Gaelic at the time. Such material also included connected prose-texts in the form of stories and anecdotes, as well as lyric-texts consisting exclusively of traditional songs, rhymes, chants, etc., either complete or in fragmentary form. Though it will be seen that many of the song-texts exist only in fragmentary form, this does not necessarily mean that the informant could not have given more. The reasons for this may be multiple: e.g. the unusual circumstances of the recordings. i.e., in the formal context of an interviewer-interviewee interface whereby the interviewee would likely not have been fully at ease. Nevertheless, the material available to us today is in my view sufficient to give us a good idea of what the informants could offer. The song-texts gathered from the last native Manx speakers are brought together for the first time to enable a concise overview

Rhydderch — Broderick?

The paper focuses on the British family name Broderick that for many years was believed, but never adequately explained, to derive from the British personal name Rhydderch. However, in the recently published Oxford Dictionary of Family Surnames in Britain and Ireland (Oxford University Press, 2016) the editors have changed tack and suggested that the name may in fact be a nickname derived from Middle English meaning ‘broad-backed, broad shouldered’, found also in English place-names in the north of England to mean ‘broad ridge’, etc. The editors supply ample examples of both the family name and the place-name in all its spellings. Whilst the forms may be suitable in place-names the given forms in the context of the family name Broderick seem to be late, as the name itself looks to be of much earlier provenance. In looking at the name the author argues that the family name Broderick in fact derives from the British personal name Rhydderch and seeks to explain the relevant phonological developments.Статья посвящена британской фамилии Broderick, которая, как давно считается (хотя эта версия так и не получила всестороннего адекватного объяснения), является производным от британского личного имени Rhydderch. В недавно опубликованном «Оксфордском словаре фамилий Британии и Ирландии» (Oxford Dictionary of Family Surnames in Britain and Ireland, 2016) редакторы заняли иную позицию, интерпретируя эту фамилию как прозвище, восходящее к среднеанглийскому слову со значением ‘ широкую спину, широкие плечи’, которое также зафиксировано в топонимии севера Англии в значении ‘широкий мост’. Составители словаря дают множество вариантов соответствующих фамилии и топоосновы, приводя примеры их функционирования. И хотя для объяснения топонимных образований приводимые формы вполне пригодны, они не могут объяснить появление фамилии Broderick, которая, по мнению автора, возникла существенно раньше упоминаемых в словаре случаев. Автор отстаивает традиционную точку зрения, согласно которой фамилия Broderick восходит к личному имени Rhydderch, и пытается объяснить соответствующие фонетические переходы

On Stochastic Inequalities and Comparisons of Reliability Measures for Weighted Distributions

Inequalities, relations and stochastic orderings, as well as useful ageing notions for weighted distributions are established. Also presented are preservation and stability results and comparisons for weighted and length-biased distributions. Relations for length-biased and equilibrium distributions as examples of weighted distributions are also presented

Surgical Capabilities for Exploration and Colonization Space Flight - An Exploratory Symposium

Identify realistic and achievable pathways for surgical capabilities during exploration and colonization space operations and develop a list of recommendations to the NASA Human Research Program to address challenges to developing surgical capabilities

The Old Bailey proceedings and the representation of crime and criminal justice in eighteenth-century London

The Proceedings of the Old Bailey, published accounts of felony trials held at London’s central criminal court, were a remarkable publishing phenomenon. First published in 1674, they quickly became a regular periodical, with editions published eight times a year following each session of the court. Despite the huge number of trial reports (some 50,000 in the eighteenth century), the Proceedings, also known as the “Sessions Papers”, have formed the basis of several important studies in social history, dating back to Dorothy George’s seminal London Life in the Eighteenth Century (1925). Their recent publication online, however, has not only made them more widely available, but also changed the way historians consult them, leading to greater use of both quantitative analysis, using the statistics function, and qualitative examination of their language, through keyword searching. In the context of recent renewed interest in the history of crime and criminal justice, for which this is the most important source available in this period, the growing use of the Proceedings raises questions about their reliability, and, by extension, the motivations for their original publication. Historians generally consider the Proceedings to present accurate, if often incomplete, accounts of courtroom proceedings. From this source, along with manuscript judicial records, criminal biographies (including the Ordinary’s Accounts), polemical pamphlets such as Henry Fielding’s Enquiry into the Causes of the Late Increase of Robbers (1751), and of course the satirical prints of William Hogarth, they have constructed a picture of eighteenth-century London as a city overwhelmed by periodic crime waves and of a policing and judicial system which was forced into wide-ranging reforms in order to meet this challenge

Individual Patient Data Subgroup Meta-Analysis of Surgery for Spontaneous Supratentorial Intracerebral Hemorrhage

Peer reviewe

Persistence of serogroup C antibody responses following quadrivalent meningococcal conjugate vaccination in United States military personnel

AbstractSerogroup C meningococcal (MenC) disease accounts for one-third of all meningococcal cases and causes meningococcal outbreaks in the U.S. Quadrivalent meningococcal vaccine conjugated to diphtheria toxoid (MenACYWD) was recommended in 2005 for adolescents and high risk groups such as military recruits. We evaluated anti-MenC antibody persistence in U.S. military personnel vaccinated with either MenACYWD or meningococcal polysaccharide vaccine (MPSV4). Twelve hundred subjects vaccinated with MenACYWD from 2006 to 2008 or MPSV4 from 2002 to 2004 were randomly selected from the Defense Medical Surveillance System. Baseline serologic responses to MenC were assessed in all subjects; 100 subjects per vaccine group were tested during one of the following six post-vaccination time-points: 5–7, 11–13, 17–19, 23–25, 29–31, or 35–37 months. Anti-MenC geometric mean titers (GMT) were measured by rabbit complement serum bactericidal assay (rSBA) and geometric mean concentrations (GMC) by enzyme-linked immunosorbent assay (ELISA). Continuous variables were compared using the Wilcoxon rank sum test and the proportion of subjects with an rSBA titer ≥8 by chi-square. Pre-vaccination rSBA GMT was <8 for the MenACWYD group. rSBA GMT increased to 703 at 5–7 months post-vaccination and decreased by 94% to 43 at 3 years post-vaccination. GMT was significantly lower in the MenACWYD group at 5–7 months post-vaccination compared to the MPSV4 group. The percentage of MenACWYD recipients achieving an rSBA titer of ≥8 decreased from 87% at 5–7 months to 54% at 3 years. There were no significant differences between vaccine groups in the proportion of subjects with a titer of ≥8 at any time-point. GMC for the MenACWYD group was 0.14μg/mL at baseline, 1.07μg/mL at 5–7 months, and 0.66μg/mL at 3 years, and significantly lower than the MPSV4 group at all time-points. Anti-MenC responses wane following vaccination with MenACYWD; a booster dose is needed to maintain protective levels of circulating antibody

Altered Response Hierarchy and Increased T-Cell Breadth upon HIV-1 Conserved Element DNA Vaccination in Macaques

HIV sequence diversity and potential decoy epitopes are hurdles in the development of an effective AIDS vaccine. A DNA vaccine candidate comprising of highly conserved p24 gag elements (CE) induced robust immunity in all 10 vaccinated macaques, whereas full-length gag DNA vaccination elicited responses to these conserved elements in only 5 of 11 animals, targeting fewer CE per animal. Importantly, boosting CE-primed macaques with DNA expressing full-length p55 gag increased both magnitude of CE responses and breadth of Gag immunity, demonstrating alteration of the hierarchy of epitope recognition in the presence of pre-existing CE-specific responses. Inclusion of a conserved element immunogen provides a novel and effective strategy to broaden responses against highly diverse pathogens by avoiding decoy epitopes, while focusing responses to critical viral elements for which few escape pathways exist