Proton imaging apparatus for protontherapy application

Radiotherapy with protons, due to the physical properties of these particles, offers several advantages for cancer therapy as compared to the traditional radiotherapy with photons. In the clinical use of proton beams, a pCT (proton Computed Tomography) apparatus can contribute to improve the accuracy of the patient positioning and dose distribution calculation. In this paper a pCT apparatus built by the PRIMA (PRoton IMAging) Italian Collaboration will be presented and the preliminary results will be discussed

The INFN-FBK "Phase-2" R&D program

We report on the 3-year INFN ATLAS-CMS joint research activity in collaboration with FBK, started in 2014, and aimed at the development of new thin pixel detectors for the High Luminosity LHC Phase-2 upgrades. The program is concerned with both 3D and planar active-edge pixel sensors to be made on 6" p-type wafers. The technology and the design will be optimized and qualified for extreme radiation hardness (2×1016 neq cm-2). Pixel layouts compatible with present (for testing) and future (RD53 65nm) front-end chips of ATLAS and CMS are considered. The paper covers the main aspects of the research program, from the sensor design and fabrication technology, to the results of initial tests performed on the first prototypes. © 2015 Elsevier B.V

Data acquisition system for a proton imaging apparatus

New developments in the proton-therapy field for cancer treatments, leaded Italian physics researchers to realize a proton imaging apparatus consisting of a silicon microstrip tracker to reconstruct the proton trajectories and a calorimeter to measure their residual energy. For clinical requirements, the detectors used and the data acquisition system should be able to sustain about 1 MHz proton rate. The tracker read-out, using an ASICs developed by the collaboration, acquires the signals detector and sends data in parallel to an FPGA. The YAG:Ce calorimeter generates also the global trigger. The data acquisition system and the results obtained in the calibration phase are presented and discussed

2D dosimeter based on monolithic silicon sensors for beam verification in conformal radiotherapy

Due to the features of modern radiotherapy techniques, such as Intensity Modulated Radiation Therapy (IMRT), Stereotactic Treatments with photons and proton therapy, where high spatial dose gradient are often present, detectors to be employed for two-dimensional dose verifications must satisfy narrow requirements. In particular, they have to exhibit high spatial resolution. For these applications, in the framework of the European Integrated project MAESTRO (LSHC-CT-2004-503564) and of the INFN experiment PRIMA, we designed a modular system based on a monolithic silicon segmented sensor. A single sensor has been coupled with readout electronics and tested with satisfactory results by using 6, 10 and 25MV X-rays from a LINAC at the University Hospital of Florence and 62MeV protons at INFN LNS Catania, following MAESTRO procedures. For photons, almost all the channels exhibit performances within project specifications (repeatability ≪0.5%, reproducibility ≪1%, deviation from linearity ≪1%, dose rate dependence ≪1%). For protons, the measured Spread Out Bragg Peak is in good agreement with the one measured with a single diode and the detector shows also a good linearity in the range 20–5000 cGy. The output factors are in agreement with those measured with ionization chamber, single diode or film, within experimental errors

Trapping in irradiated p-on-n silicon sensors at fluences anticipated at the HL-LHC outer tracker

The degradation of signal in silicon sensors is studied under conditions expected at the CERN High-Luminosity LHC. 200 $\mu$m thick n-type silicon sensors are irradiated with protons of different energies to fluences of up to $3 \cdot 10^{15}$ neq/cm$^2$. Pulsed red laser light with a wavelength of 672 nm is used to generate electron-hole pairs in the sensors. The induced signals are used to determine the charge collection efficiencies separately for electrons and holes drifting through the sensor. The effective trapping rates are extracted by comparing the results to simulation. The electric field is simulated using Synopsys device simulation assuming two effective defects. The generation and drift of charge carriers are simulated in an independent simulation based on PixelAV. The effective trapping rates are determined from the measured charge collection efficiencies and the simulated and measured time-resolved current pulses are compared. The effective trapping rates determined for both electrons and holes are about 50% smaller than those obtained using standard extrapolations of studies at low fluences and suggests an improved tracker performance over initial expectations

Performance studies of the CMS strip tracker before installation

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CMS physics technical design report : Addendum on high density QCD with heavy ions

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