16 research outputs found
Update on the correlation of the highest energy cosmic rays with nearby extragalactic matter
Data collected by the Pierre Auger Observatory through 31 August 2007 showed
evidence for anisotropy in the arrival directions of cosmic rays above the
Greisen-Zatsepin-Kuz'min energy threshold, \nobreak{eV}. The
anisotropy was measured by the fraction of arrival directions that are less
than from the position of an active galactic nucleus within 75 Mpc
(using the V\'eron-Cetty and V\'eron catalog). An updated
measurement of this fraction is reported here using the arrival directions of
cosmic rays recorded above the same energy threshold through 31 December 2009.
The number of arrival directions has increased from 27 to 69, allowing a more
precise measurement. The correlating fraction is , compared
with expected for isotropic cosmic rays. This is down from the early
estimate of . The enlarged set of arrival directions is
examined also in relation to other populations of nearby extragalactic objects:
galaxies in the 2 Microns All Sky Survey and active galactic nuclei detected in
hard X-rays by the Swift Burst Alert Telescope. A celestial region around the
position of the radiogalaxy Cen A has the largest excess of arrival directions
relative to isotropic expectations. The 2-point autocorrelation function is
shown for the enlarged set of arrival directions and compared to the isotropic
expectation.Comment: Accepted for publication in Astroparticle Physics on 31 August 201
Direct observation and control of near-field radiative energy transfer in a natural hyperbolic material
Heat control is a key issue in nano-electronics, where new efficient energy
transfer mechanisms are highly sought after. In this respect, there is indirect
evidence that high-mobility hexagonal boron nitride (hBN)-encapsulated graphene
exhibits hyperbolic out-of-plane radiative energy transfer when driven
out-of-equilibrium. Here we directly observe radiative energy transfer due to
the hyperbolic phonon polaritons modes of the hBN encapsulant in intrinsic
graphene devices under large bias, using mid-infrared spectroscopy and
pyrometry. By using different hBN crystals of varied crystalline quality, we
engineer the energy transfer efficiency, a key asset for compact thermal
management of electronic circuits.Comment: 21 pages including Supplementary Material (Main text: 10 pages, 4
figures
Acoustic turbulence measurements of near-bed suspended sediment dynamics in highly turbid waters of a macrotidal estuary
Sediment-turbulence interactions near the bed are still poorly understood in highly turbid estuaries, especially in the presence of fluid mud layers. This results primarily from the difficulty in measuring co-located velocity and suspended sediment concentration (SSC) at sufficiently high rate to resolve small turbulent flow scales. In this paper, we show how a set of commercial acoustic and optical bacicscattering systems known as ADCPs, ADVs and OBSs, can be deployed and used in a complementary way to perform large-scale profilings of tidal current and SSC combined with high-resolution velocity and SSC measurements in the highly turbid near-bed zone. The experiment was done in the Gironde estuary (France) which is well known for its turbidity maximum zone characterized by high SSC values, above 1 g l(-1) near the surface. A first simple inversion method is proposed to convert the backscattered acoustic intensity measured with ADV into SSC data in the highly turbid near-bed zone. Near-bed SSC data from the OBS are used to compensate for the important acoustic sediment attenuation effect at an acoustic frequency of 6 MHz. No a priori knowledge of acoustic backscattering properties of mud suspensions is required with this calibration procedure. We obtain an attenuation coefficient for mud suspensions of 0.28 m(2)/kg at 6 MHz leading to a good agreement between the SSC timeseries from the three ADV receivers and the OBS over the entire tidal cycle. The obtained SSC data are then analyzed with respect to the near-bed velocity, Reynolds shear stress and turbulent kinetic energy (TKE) timeseries in order to identify the relevant sediment transport processes during the tidal cycle. Significant differences in bed shear stress and TICE levels are found between ebb and flood stages with effects on near-bed sediment dynamics. During the ebb, maximum levels of tidal current, bed shear stress and TKE are associated with a reduction of near-bed sediment concentration (from 400 kg m(-3) down to 100 kg m(-3)). Bed liquefaction process is assumed to occur at this moment with the presence of highly concentrated mud layer and a possible lutocline at a distance of less than 20 cm above the bed. During the first 1.5 h of flood, turbulent activity remains moderate. The near-bed flood current is then inhibited very abruptly while a sudden increase in SSC occurred above the bed. Assuming that the ADV is able to estimate relevant turbulent erosion fluxes, the co-located velocity and SSC are multiplied and compared with settling flux measurements made onboard under quiescent water conditions. The mean sediment settling fluxes (averaged over 3 min) increase with SSC and are in relative good coherence with fluxes in quiescent water below the hindered regime, for SSC below 15 g l(-1). Reducing averaging time from 3 min to 30 s allows to increase the range of turbulent fluxes and SSC values, up to 99 g l(-1). At this scale, fluxes keep increasing quasi-linearly at higher SSC, suggesting the inhibition (delay or reduction) of the hindered settling regime as previously shown by Gratiot et al. (2005) from laboratory experiments. However, the 3-min averaged concentration field remained too low to conclude definitively on the effectiveness of such a process. Further analysis conducted at higher SSC regimes and under fully verified equilibrium are necessary
Cancer clinical research in Latin America: Current situation and opportunities. Expert opinion from the first ESMO workshop on clinical trials, Lima, 2015
Latin America and the Caribbean have not yet developed strong clinical cancer research programmes. In order to improve this situation two international cancer organisations, the Latin American Society of Clinical Oncology (SLACOM) and the European Society of Medical Oncology (ESMO) worked closely with the Peruvian Cooperative Oncology Group (GECOPERU) and organised a clinical cancer research workshop held in Lima, Peru, in October 2015. Many oncologists from different Latin American countries participated in this gathering. The opportunities for and strengths of clinical oncology research in Latin American and Caribbean countries were identified as the widespread use of the Spanish language, the high cancer burden, growing access to information, improving patient education, access to new drugs for research centres, regional networks and human resources. However, there are still many weaknesses and problems including the long timeline for regulatory approval, lack of economic investment, lack of training and lack of personnel participating in clinical research, lack of cancer registries, insufficient technology and insufficient supplies for the diagnosis and treatment of cancer, few cancer specialists, low general levels of education and the negative attitude of government authorities towards clinical research. © Published by the BMJ Publishing Group Limited