26 research outputs found
Functional Characteristics of a Highly Specific Integrase Encoded by an LTR-Retrotransposon
- Author
- A Engelman
- AG Holman
- Babacar Faye
- Bernard Dastugue
- Chantal Vaury
- D Esposito
- D Pruss
- DA Wah
- DJ Finnegan
- DL Chalker
- E Baldrich
- E Check
- Emilie Brasset
- EP Johnson
- Eric Peyretaillade
- F Arnaud
- F Bushman
- FD Bushman
- Frederick Arnaud
- J Dai
- J Kirchner
- JD Boeke
- Jean-Nicolas Volff
- JM Coffin
- JM Kim
- KD Taganov
- LF Maxfield
- MK Lewinski
- MK Lewinski
- P Leblanc
- P Leblanc
- PM Pryciak
- PM Pryciak
- RS Mitchell
- S Desset
- SE Devine
- SM Christensen
- SP Goff
- TL Brady
- W Xie
- X Wu
- X Wu
- X Wu
- Y Zhu
- Y Zhu
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2008
- Field of study
Background: The retroviral Integrase protein catalyzes the insertion of linear viral DNA into host cell DNA. Although different retroviruses have been shown to target distinctive chromosomal regions, few of them display a site-specific integration. ZAM, a retroelement from Drosophila melanogaster very similar in structure and replication cycle to mammalian retroviruses is highly site-specific. Indeed, ZAM copies target the genomic 59-CGCGCg-39 consensus-sequences. To enlighten the determinants of this high integration specificity, we investigated the functional properties of its integrase protein denoted ZAM-IN. Principal Findings: Here we show that ZAM-IN displays the property to nick DNA molecules in vitro. This endonuclease activity targets specific sequences that are present in a 388 bp fragment taken from the white locus and known to be a genomic ZAM integration site in vivo. Furthermore, ZAM-IN displays the unusual property to directly bind specific genomic DNA sequences. Two specific and independent sites are recognized within the 388 bp fragment of the white locus: the CGCGCg sequence and a closely apposed site different in sequence. Conclusion: This study strongly argues that the intrinsic properties of ZAM-IN, ie its binding properties and its endonuclease activity, play an important part in ZAM integration specificity. Its ability to select two binding sites and to nick the DNA molecule reminds the strategy used by some site-specific recombination enzymes and forms the basis for site-specifi
Orientation-dependent interaction between Drosophila insulators is a property of this class of regulatory elements
- Author
- A. Kullyev
- Adryan
- Avramova
- Banzhaf
- Blanton
- Bonifer
- Brasset
- Cai
- Cai
- Capelson
- Ciavatta
- Conte
- Cuvier
- D. Chetverina
- Dennis
- Dunaway
- Gaszner
- Geyer
- Geyer
- Glover
- Golic
- Golovnin
- Gruzdeva
- Gyurkovics
- Hart
- Hogga
- Holdridge
- Holohan
- Ishii
- Karess
- Kellum
- Kellum
- Kravchenko
- Kuhn
- Kuhn
- Kuhn
- Ling
- Mohan
- Moon
- Muravyova
- Mutskov
- O. Kyrchanova
- O. Maksimenko
- Oki
- P. Georgiev
- Pai
- Parnell
- Pirrotta
- Qian
- Rodin
- Roseman
- Roseman
- Scott
- Scott
- Siegal
- Sigrist
- Sun
- Udvardy
- Valenzuela
- Vazquez
- Wallace
- Zhao
- Zhao
- Publication venue
- Oxford University Press
- Publication date
- Field of study
Insulators are defined as a class of regulatory elements that delimit independent transcriptional domains within eukaryotic genomes. According to previous data, an interaction (pairing) between some Drosophila insulators can support distant activation of a promoter by an enhancer. Here, we have demonstrated that pairs of well-studied insulators such as scs–scs, scs’–scs’, 1A2–1A2 and Wari–Wari support distant activation of the white promoter by the yeast GAL4 activator in an orientation-dependent manner. The same is true for the efficiency of the enhancer that stimulates white expression in the eyes. In all insulator pairs tested, stimulation of the white gene was stronger when insulators were inserted between the eye enhancer or GAL4 and the white promoter in opposite orientations relative to each other. As shown previously, Zw5, Su(Hw) and dCTCF proteins are required for the functioning of different insulators that do not interact with each other. Here, strong functional interactions have been revealed between DNA fragments containing binding sites for either Zw5 or Su(Hw) or dCTCF protein but not between heterologous binding sites [Zw5–Su(Hw), dCTCF–Su(Hw), or dCTCF–Zw5]. These results suggest that insulator proteins can support selective interactions between distant regulatory elements
The Epigenetic Trans-Silencing Effect in Drosophila Involves Maternally-Transmitted Small RNAs Whose Production Depends on the piRNA Pathway and HP1
- Author
- A Bucheton
- A Girard
- A Pane
- A Pelisson
- A Pelisson
- Anne-Laure Todeschini
- B Brower-Toland
- B Czech
- B Lemaitre
- C Klattenhoff
- C Li
- CD Malone
- CJ O'Kane
- D Coen
- D Fagegaltier
- D Reiss
- D Zilberman
- DC Rio
- DE Cryderman
- E Brasset
- EN Andreyeva
- F Chalvet
- FA Laski
- FK Teixeira
- G Picard
- GH Karpen
- H Biessmann
- H Yin
- HJ Bellen
- J Brennecke
- J Brennecke
- JC Eissenberg
- JP Blumenstiel
- JR Stuart
- JS Tushir
- K Forstemann
- K Mochizuki
- K Noma
- K Okamura
- K Saito
- KJ Haley
- L Marin
- Laure Teysset
- M Pal-Bhadra
- M Savitsky
- Mary Bryk
- MG Kidwell
- MJ Simmons
- MJ Simmons
- MS Klenov
- NL Vastenhouw
- Q Liu
- RC Frydrychova
- RK Slotkin
- S Chambeyron
- S Desset
- S Desset
- S Jensen
- S Ronsseray
- S Ronsseray
- S Ronsseray
- S Ronsseray
- S Ronsseray
- SE Roche
- SI Grewal
- Stéphane Ronsseray
- T Josse
- T Josse
- T Schupbach
- T Sugiyama
- TA Volpe
- Valérie Delmarre
- VV Vagin
- WR Engels
- WR Engels
- WR Engels
- X Dramard
- Z Lippman
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2010
- Field of study
BACKGROUND: The study of P transposable element repression in Drosophila melanogaster led to the discovery of the Trans-Silencing Effect (TSE), a homology-dependent repression mechanism by which a P-transgene inserted in subtelomeric heterochromatin (Telomeric Associated Sequences, "TAS") has the capacity to repress in trans, in the female germline, a homologous P-lacZ transgene located in euchromatin. Phenotypic and genetic analysis have shown that TSE exhibits variegation in ovaries, displays a maternal effect as well as epigenetic transmission through meiosis and involves heterochromatin (including HP1) and RNA silencing. PRINCIPAL FINDINGS: Here, we show that mutations in squash and zucchini, which are involved in the piwi-interacting RNA (piRNA) silencing pathway, strongly affect TSE. In addition, we carried out a molecular analysis of TSE and show that silencing is correlated to the accumulation of lacZ small RNAs in ovaries. Finally, we show that the production of these small RNAs is sensitive to mutations affecting squash and zucchini, as well as to the dose of HP1. CONCLUSIONS AND SIGNIFICANCE: Thus, our results indicate that the TSE represents a bona fide piRNA-based repression. In addition, the sensitivity of TSE to HP1 dose suggests that in Drosophila, as previously shown in Schizosaccharomyces pombe, a RNA silencing pathway can depend on heterochromatin components
Global disparities in surgeons’ workloads, academic engagement and rest periods: the on-calL shIft fOr geNEral SurgeonS (LIONESS) study
- Author
- Abdelkhalek Mohamed
- Abellán Antonio Melero
- Abelló David
- Abu-Arish Hamdoon
- Acevedo Ana Karen Radilla
- Adamina Michel
- Adamovich Dmitry Mikhailovich
- Addeo Pietro
- Adewunmi Olayinka Lukman
- Aeschbacher Pauline
- Afolabi Akinwale Ibrahim
- Agastra Ervis
- Agresta Ferdinando
- Aguilar Juan Carlos Cardozo
- Ahmed Bensaad
- Ahmed Nauman
- Aimal Aimal Khan
- Aiolfi Alberto
- Akay Omer
- al-Najami Issam
- Al-Shehari Mohammed
- Alconchel Felipe
- Alesina Pier Francesco
- Alhazmi Ahmad
- Ali Mahmoud Ibrahim
- Aliyev Vusal
- Alonso Patricia
- Aloun Ali
- Altinel Yuksel
- Altomare Michele
- Alvarez-Gallego Mario
- Ammendola Michele
- Ammerata Giorgio
- Anania Marco
- Anas Abdelhmed
- Andreuccetti Jacopo
- Andriola Valeria
- Andriola Valeria
- Anelli Ferdinando M.
- Anestiadou Elissavet
- Angrisani Marco
- Antonacci Nicola
- Antonacci Nicola
- Antonelli Amedeo
- Antropoli Carmine
- Aparicio Antonio Carlos Maya
- Apostolou Konstantinos
- Arcudi Claudio
- Aregawi Alazar Berhe
- Argenio Giulio
- Ascari Francesca
- Asfaw Fitsum Terefe
- Athar Rahmatullah
- Atici Semra Demirli
- Au Stephanie
- Augustin Goran
- Avella Pasquale
- Avellaneda Nicolas
- Awad Ahmed K.
- Awad Selmy S.
- Awad Selmy S.
- Ayalew Alem Mekete
- Aytac Erman
- Aytac Erman
- Azevedo José
- Baba Arshad Ahmed
- Bacchiocchi Giulia
- Bagaglini Giulia
- Bagaria Dinesh
- Baili Efstratia
- Bains Lovenish
- Baiocchi Gian Luca
- Bala Miklosh
- Balaphas Alexandre
- Balassone Valerio
- Baldi Caterina
- Baldini Edoardo
- Balla Andrea
- Ballester Cristina
- Bandaru Kalyan Vijay Kumar
- Bandyopadhyay Samik K.
- Bannone Elisa
- Barba Leonardo A.
- Barberis Andrea
- Barone Mirko
- Barranquero Alberto G.
- Barugola Giuliano
- Barzola Ernesto J.
- Batıkan Oğuzkağan
- Bavikatte Akshay Prasannakumar
- Bayileyegn Nebiyou Simegnew
- Bedros Nicole Mary
- Beisani Marc
- Bejiga Gosa Hundie
- Bekana Bekana L.
- Belay Tatek
- Belia Francesco
- Belkacem Acidi
- Bellanova Giovanni
- Bellato Vittoria
- Bellido-luque Juan
- Bellini Maria Irene
- Bellver Pedro Palazón
- Benzoni Enrico
- Benzoni Ilaria
- Bergna Alessandro
- Bhat Pawan Singh
- Bhattacharya Kaushik
- Bhattacharya Neela
- Bhatti Hamza Waqar
- Bianchi Valentina
- Bianco Giuseppe
- Biloslavo Alan
- Biniam Ewnte
- Blanco-Antona Francisco
- Bocchino Antonio
- Bointas Georgios
- Bollino Ruggero
- Bonavina Luigi
- Bondurri Andrea
- Bonilla Fernando
- Bonito Alba Correa
- Bono Dario
- Borges Nuno
- Botelho Pedro
- Bottari Andrea
- Bottcher Sofia Maria Jaume
- Bourguiba Mohamed Aboulkacem
- Bourmpouteli Eirini
- Bouzid Chafik
- Braccio Bartolomeo
- Brady Richard R. W.
- Braholli Eriol
- Brasset Camille
- Brillantino Antonio
- Brillantino Antonio
- Briones Cristhian Gonzalo Aspiazu
- Brisinda Giuseppe
- Brito Ismael
- Brookes Charlotte Elisabeth
- Brucchi Francesco
- Bulte Joris P.
- Buonomo Oreste Claudio
- Butler Rebecca Jayne
- Cacciaguerra Andrea Benedetti
- Caldeira Beatriz
- Calini Giacomo
- Calu Valentin
- Calussi Marco
- Calussi Marco
- Cammarat Roberto
- Cammarata Roberto
- Campagnaro Tommaso
- Campanelli Michela
- Campisi Andrea
- Campus Federica
- Candilio Giuseppe
- Cannavo Maurizio
- Cannistra Marco
- Cannistra Marco
- Cano-Valderrama Oscar
- Canonico Giuseppe
- Cantarino Frederico
- Capitano Sante
- Capolupo Gabriella Teresa
- Cappuccio Micaela
- Capuano Marianna
- Capuano Marianna
- Caputo Damiano
- Carannante Filippo
- Carbone Ludovico
- Cardinali Luca
- Carneros Virginia Jiménez
- Carrabetta Salvatore
- Caruso Riccardo
- Carvas João M.
- Carvas João M. B.
- Casagranda Biagio
- Casas Maria Agustina
- Cascales-Sanchez Pedro
- Cassese Gianluca
- Castaldi Antonio
- Castaldi Antonio
- Castellano Javier Rivera
- Castro Ernest
- Castro Maria J.
- CC Tommaso
- Celentano Valerio
- Celotti Andrea
- Cerdán-Santacruz Carlos
- Cereda Marco Angelo
- Ceresoli Marco
- Cero Mariagiulia Dal
- Cestaro Giovanni
- Cestino Luca
- Chai Feng Yih
- Chalkoo Mushtaq A.
- Charalabopoulos Alexandros
- Charalabopoulos Alexandros
- Charitaki Evgenia
- Chessa Antonella
- Chessa Antonella
- Chevallay Mickael
- Chia Chi Fung
- Chillarge Gauri
- Chimenti Federica
- Chitul Andrei
- Chiu Jennifer H. F.
- Chooklin Serge
- Choudhry Asad
- Chouliaras Christos
- Chowdhury Ashim
- Christodoulou Prokopis
- Chrysikos Michael
- Chukwu Isaac Sunday
- Cianci Pasquale
- Ciarleglio Francesco A.
- Cicerchia Pierfranco Maria
- Ciesielski Wojciech J.
- Cigognini Maria
- Cillara Nicola
- Cioffi Stefano Piero Bernardo
- Ciro Mauricio Pedraza
- Clementi Marco
- Clocchiatti Lucrezia
- Colak Elif
- Colás-Ruiz Enrique
- Coletta Diego
- Colombari Renan C.
- Colombo Francesco
- Colucci Gianluca
- Conte Luigi E.
- Conti Luigi
- Coppola Alessandro
- Corallino Diletta
- Corronca Federico
- Corrons Laia Codina
- Corvasce Arianna
- Costantini Giulia
- Costanzo Antonio
- Costea Radu V.
- Cotsoglou Christian
- Cozza Valerio
- Creavin Ben
- Cremona Simone
- Cricrì Michele
- Crosbie Gonzalo Gabriel
- Cuccomarino Salvatore
- Cuk Vladica
- Cunha Miguel
- Curcio Silvia
- Curro Giuseppe
- Dajti Irida
- Daniel Clerc
- Dardanov Dragomir
- Davey Matthew G.
- Davies Justin
- Davis Daniel G.
- De Andrés-Asenjo Beatriz
- De Campos Tercio
- De Carlis Riccardo
- de las Casas Sara Gortázar
- De Luca Alessandro
- De Luca Raffaele
- De Lucia Chiara
- De Nobili Giovanni
- de Oliveira Gabriel Paiva
- De Padua Cristina
- De Rosa Michele
- de Sa Tiago Correia
- de Santos Iglesias Francisco Juan
- De Simone Belinda
- de Vries Hilbert S.
- Debela Bizuneh Sime
- Debena Dawit Gebregiorgis
- Deerenberg Eva B.
- Del Monte Simone Rossi
- del Olmo Juan Carlos Martín
- Delaune Vaihere
- Delgado Ander Timoteo
- Delis Spiros
- Delogu Daniele
- Delvecchio Antonella
- Demir Anıl
- Devriendt Stefanie
- Di Bella Annamaria
- Di Carlo Isidoro
- Di Filippo Giacomo
- Di Franco Gregorio
- Di Lascio Pierpaolo
- Di Marco Federica
- Di Marco Federica
- Di Marco Federica
- Di Martino Marcello
- Di Martino Marcello
- Di Meo Giovanna
- di Mola Fabio F.
- Di Santo Albini Andrea G.
- Di Saverio Salomone
- Di Saverio Salomone
- Di Venere Beatrice
- Diaz-Elizondo Jose Antonio
- Diaz-Elizondo Jose Antonio
- Digne-Malcolm Holly Jane
- Dimitrov Evgeni
- Dinagde Tesfaye Aga
- Díaz Carlos JGómez
- Don Cristine Brooke Pathirannehalage
- Dorovinis Panagiotis
- Douka Eleftheria
- Drogouti Maria
- Dudi-Venkata Nagendra N.
- Dulskas Audrius
- Dulskas Audrius
- Dziakova Jana
- D’Acapito Fabrizio
- D’Ambrosio Marco
- D’Ambrosio Marco
- D’Ugo Stefano
- Efetov Sergey
- Efetov Sergey
- Elfeki Hossam
- Elghadban Hosam Mohamed
- Emile Sameh
- Ercolani Giorgio
- Erdoğan Emre
- Ermias Nebiyou
- Escalante Karol S.
- Espino Eduardo Morales
- Esposito Francesco
- Esposito Giuseppe
- Estaire-Gómez Mercedes
- Fabbri Nicolò
- Fabbrizio Tiziana
- Farazi-Chongouki Christos
- Faro Carmelo Lo
- Faro Carmelo Lo
- Farolfi Tommaso
- Farooqui Marryam Riaz
- Farrarons Sara Sentí
- Farré Silvia Pérez
- Farrukh Maira
- Fazio Federico
- Feituri Nura
- Feleke Tsega Terefe
- Felsenreich Daniel M.
- Fernandez Carmen Cagigas
- Fernández Fernández June
- Fernicola Agostino
- Ferrara Francesco
- Ferrari Davide
- Ferrario Luca
- Ferreira Rodrigo Vaz
- Ferretti Carlotta
- Ferronetti Antonio
- Festa Federico
- Fichera Alessandro
- Fiore Felicia
- Fleming Andrew Martin
- Fleres Francesco
- Florio Gaetano
- Folliero Cristina
- Fonseca Vinicius Cordeiro
- Forcignanò Edoardo
- Foreman Michaael L.
- Formisano Giampaolo
- Fortuna Laura
- Franchi Eloisa
- Francis Fayez Maged
- Francone Elisa
- Francone Elisa
- Fransvea Pietro
- Frazzetta Giuseppe
- Freixa Celia Caula
- Frontali Alice
- Frountzas Maximos
- Funk Geoffrey A.
- Fuschillo Giacomo
- Gachabayov Mahir
- Galeev Shamil I.
- Galiffa Giampaolo
- Gall Malina ECaraiman
- Gallardo Cristian
- Gallo Gaetano
- Garoufalia Zoe
- Garzali Ibrahim Umar
- Gauci Chahaya M.
- Gazia Carlo
- Gerogiannis Ioannis
- Gervasi Maria Clelia
- Gessa Emanuela
- Ghannam Wagih
- Gherardi Dario
- Ghignone Federico
- Gialamas Eleftherios
- Giambusso Mauro
- Gica Nicolae
- Giordano Alessio
- Giordano Marco
- Giovine Gennaro
- Giuffrida Maria Carmela
- Giuffrida Mario
- Giuliani Antonio
- Giuliani Giuseppe
- Glasbey James
- Gomes Carlos Augusto
- Gonfa Kebebe Bekele
- Gonsaga Ricardo Alessandro Teixeira
- Gonzalez Ana
- González Lluis García
- González Tomas Elosua
- Gourgiotis Stavros
- Gómez Marta Jiménez
- Gómez Marta Jiménez
- Göktepe Berk
- Grama Florin A.
- Granata Roberta
- Gravante Gianpiero
- Greco Antonio
- Grimaldi Luciano
- Grossi Ugo
- Guerci Claudio
- Guerrero María Alejandra
- Guevara Jenny
- Guitart Marc Pérez
- Gulcu Baris
- Guler Mert
- Gulmez Mehmet
- Gunay Emre
- Gupta Amit
- Gupta Ashish
- Gussago Stefano
- Gülcü Barış
- Güngör Mert
- Hailemariam Dagnachew H.
- Halder Subhadip
- Hale Lyman Lansing
- Harvitkar Rafique Umer
- Hassen Khalid Arebo
- Hernandez-Garcia Miguel
- Hernández Edgard Efrén Lozada
- Horesh Nir
- Iacobone Maurizio
- Iannone Immacolata
- Ibáñez Noelia
- Ibrahim Aini Fahriza
- Idiz Ufuk Oguz
- Ielpo Benedetto
- Ielpo Benedetto
- Imana Ruhama Yoseph
- Inama Marco
- Ingallinella Sara
- Ingallinella Sara
- Ioannidis Argyrios
- Ioannidis Orestis
- Iodice Alessandra
- Ioia Giovanna
- Iordache-Petrescu Madalina Ionela
- Iossa Angelo
- Iqbal Muhammad Rafaih
- Iranzo Marina Alarcón
- Isik Arda
- Izzo Giuliano
- Jamiri Al-Radjid
- Jansson Hannes
- Johnson Benjamin E.
- Jordão Daniel Filipe Martins
- Juloski Jovan
- Junior Marcelo A. F. Ribeiro
- Kampouroglou Georgios
- Kapsampelis Panagiotis
- Kara Yasin
- Karamarkovic Aleksandar
- Karamarkovic Aleksandar
- Karamarkovic Aleksandar
- Kaur Mandeep
- Kchaou Ali
- Kebede Kirubel Abebe
- Keci Laura
- Keller Deborah S.
- Kelly Michael E.
- Khan Huma Ahmed
- Khan Jan Sher
- Khan Mansoor
- Khobragade Krunal H.
- Kiros Samuel
- Klib Mohamad
- Klimczak Tomasz Jerzy
- Knickerbocker Chase Barrett
- Kobe Yoshiro
- Koëter Tijmen
- Koh Peng Soon
- Komaei Iman
- Koneti Akshadhar J.
- Konstantoudakis Georgios
- Koppel Darren
- Korkoman Mohammed J.
- Kosir Jurij A.
- Kovacevic Bojan
- Krsicka Petr
- Kucuk Gultekin Ozan
- Kucukarslan Rabia
- Kykalos Stylianos
- La Vaccara Vincenzo
- Labat Miriam Cazador
- Lafranceschina Stefano
- Lancellotti Francesco
- Landaluce-Olavarria Aitor
- Lapolla Pierfrancesco
- Laracca Giovanni Guglielmo
- Lasarte Mateusz PJęckowski Aingeru Sarriuga
- Lasithiotakis Konstantinos
- Lauricella Sara
- Lee Lee Yeong Sing
- Lenz Jorge Godoy
- Leo Cosimo Alex
- Lesko Dusan
- Leventoglu Sezai
- Levi Sandri Giovanni Battista
- Lianos Georgios D.
- Licardie Eugenio
- Lichliter Warren E.
- Linares Neiling Massiel Oviedo
- Lisi Giorgio
- Lisi Giorgio
- Litta Francesco
- Litvin Andrey
- Locci Eleonora
- Lolis Evangelos
- Lopez Maria Martinez
- Lorente-Poch Leyre
- Lorenzo Irving
- Lostoridis Eftychios
- Low Juin
- López María Martínez
- López-López Victor
- López-Soler Guillermo
- Luberto Antonio
- Luglio Gaetano
- Lukmonov Saidrakhim
- Luque Eduardo J.
- Luzzi Andrea Pierre
- Machairas Nikolaos
- Madrid Fausto A.
- Maggi Giulia
- Major Piotr
- Malerba Michele
- Malerba Michele
- Mambrilla Sara
- Mambrilla Sara
- Manatakis Dimitrios K.
- Manfredelli Simone
- Manfredelli Simone
- Mangana Orsalia
- Manigrasso Michele
- Manrique Mario Montes
- Manrique Mario Montes
- Mansour Ahmed Mohammed Farid Mahmoud
- Manto Ottavia
- Manzo Carlo Alberto
- Marafante Chiara
- Marano Alessandra
- Marano Luigi
- Maraska Fatlum
- Marchegiani Francesco
- Marin Jacopo Nicolò
- Marinis Athanasios
- Marino Fabio
- Marino Marco V.
- Maroni Norvana
- Marra Angelo Alessandro
- Marra Ester
- Marrano Enrico
- Marsanic Patrizia
- Marsella Valentina Enrica
- Martines Gennaro
- Martini Francesco
- Martín-Pérez Beatriz
- Martínez Isidro
- Maruccia Michele
- Marwat Muhammad Ibrahim
- Marziali Irene
- Mascherini Matteo
- Mascianà Gianluca
- Masetti Michele
- Masior Łukasz
- Massaro Daniele
- Massey Lisa H.
- Mastella Federica
- Mastronardi Manuela
- Materazzo Marco
- Materazzo Marco
- Mattioli Marco
- Mazzarella Gennaro
- Mc Farlane Sebastian Jeri
- Mccawley Niamh
- Medappil Noushif
- Medas Fabio
- Melberga Liene
- Mendes Beatriz ISilva
- Meneghini Simona
- Menegozzo Carlos Augusto Metidieri
- Menéndez Jaime Iturbe
- Menna Maria Paola
- Menna Maria Paola
- Mercado Octavio Avila
- Merlini David
- Merlini David A.
- Merlini Ilenia
- Merlo Ignacio Guillermo
- Meyer Jeremy
- Michael Michael
- Mifsut Patricia
- Miggino Marco
- Miguel Gustavo Machain
- Migueláñez Isabel Pascual
- Mihailescu Andrei
- Mihailescu Andrei
- Milana Flavio
- Milana Flavio
- Milanesi Maria
- Milito Pamela
- Milne David M.
- Mineccia Michela
- Miotto Marco
- Mitul Ashrarur Rahman
- Moeckli Beat
- Moggia Elisabetta
- Mohamad Mohamad Ikhwan Sani
- Mohammed Abdullahi Ibrahim
- Mohammed Mohammed Mustafa
- Moletta Lucia
- Moncada-Ortega Augusto
- Mondi Isabella
- Montcusí Blanca
- Montiel Carmen Galiana
- Montuori Mauro
- Morales Emilio J.
- Morales Emilio J.
- Morales-Conde Salvador
- Morelli Luca
- Morini Andrea
- Moro-Valdezate David
- Mosca Vinicio
- Mukherjee Indraneil
- Mulita Francesk
- Mulpuri Venu Bhargava
- Muñoz-Cruzado Virginia Durán
- Muriel Maria Emilia
- Murillo Gabriela Aracelly Arroyo
- Murzi Valentina
- Mutlu Arda Ulaş
- Muttillo Edoardo Maria
- Nacion Aeris Jane D.
- Naeem Awais
- Nagarajan Prasanth
- Naik Prashant
- Napetti Sara
- Nardo Bruno
- Nari Gustavo Adrian
- Natalia Savvala N.
- Nava Andrea Kazemi
- Navarro-Sánchez Antonio
- Nazir Fozia
- Nazir Fozia
- Neary Peter M.
- Negasa Tolera A.
- Negoi Ionut
- Neri Ignacio
- Neves Fernanda V. S.
- Newton Carla Joyce
- Nicolaescu Diana C.
- Nicolazzi Marco
- Nidaw Melkamu Kibret
- Nigri Giuseppe
- Nigri Giuseppe
- NL Harish
- Ntomi Vasileia
- null null
- Nunziante Marco
- Obiagwu Ndubuisi K.
- Oddis Lidia
- Oddis Lidia
- Oliva Alba
- Olivier James B.
- Olivieri Laura
- Olmi Stefano
- Ortega Irene
- Ortega Nuria
- Ortenzi Monica
- Ossola Paolo
- Pach Radoslaw
- Pachajoa Diana Alejandra Pantoja
- Pacilli Mario
- Palmisano Silvia
- Palomba Giuseppe
- Panaccio Paolo
- Pandanaboyana Sanjay
- Pangeni Anang
- Paniagua-Garcia-Señorans Marta
- Panyko Arpád
- Pañella Clara
- Papadopoulos Aristeidis
- Papatheodorou Panayiotis
- Paradiso Giulia
- Paramasvaran Ganendra
- Paranyak Mykola
- Parreño-Manchado Felipe Carlos
- Pascale Marco Maria
- Pascual Franco
- Pasculli Alessandro
- Paspala Anna
- Pata Francesco
- Pata Francesco
- Pattacini Gianmaria Casoni
- Pavlovic Mladen
- Pavone Giovanna
- Pazos Natalia Suárez
- Pecorelli Nicolò
- Pedrazzani Corrado
- Pelegrina Amalia
- Pellicciaro Marco
- Pellino Gianluca
- Pellino Gianluca
- Peloso Andrea
- Pennisi Damiano
- Perez Guillermo
- Perez-Sanchez Luis E.
- Perfecto Arkaitz
- Perotti Bruno
- Perra Teresa
- Perrone Gennaro
- Pesce Antonio
- Petagna Lorenzo
- Peters Paul Adewunmi
- Petrakis Georgios
- Petropoulou Thalia
- Petrucciani Niccolo
- Pérez Raquel Escalera
- Pérez-Bertólez Sonia
- Pham Thuy Vy
- Picardi Biagio
- Picchetto Andrea
- Piccoli Micaela
- Piccolo Gaetano
- Pierobon Elisa Sefora
- Pilia Tiziana
- Pinotti Enrico
- Pio Luca
- Piozzi Guglielmo N.
- Piras Carla
- Pisaniello Donatella
- Pisano Marcello
- Pisano Michele
- Pisanu Adolfo
- Podda Mauro
- Podda Mauro
- Poillucci Gaetano
- Police Andrea
- Porcellini Iride
- Porcu Alberto
- Potkonjak Dario
- Poto Gianmario Edoardo
- Pouwels Sjaak
- Pozza Gioia
- Pradelle Irene
- Prieto Mikel
- Puccioni Caterina
- Puglisi Silvana Bernadetta
- Queffurus Michael
- Quiroga-Garza Alejandro
- Qureshi Ahmad Uzair
- Rachadell Juan José
- Ramos-De la Medina Antonio
- Rasheed Faaiz
- Rashid Arshad
- Reccia Isabella
- Reid Rebecca
- Reitano Elisa
- Reiti Andrian
- Richards Chris B.
- Rico Douglas
- Rida Khaled
- Ridolfi Cristina
- Rizzuto Antonia
- Roat Rajesh
- Rocca Aldo
- Rodas Edgar B.
- Rodriguez Agustin E.
- Rodriguez-Lopez Mario
- Roesel Raffaello
- Roesel Raffaello
- Rojas-Bonet Noel
- Romano Angela
- Romano Fabrizio
- Romano Francesco Maria
- Romanzi Andrea
- Rompianesi Gianluca
- Ros Emilio Peña
- Rosa Fausto
- Rosa Fausto
- Roscio Francesco
- Rosés Helena Salvador
- Rossi Stefano
- Rosso Edoardo
- Rottoli Matteo
- Rubio Ainhoa Valle
- Rueda Erick
- Rusli Siti Mayuha
- Russo Alfio Alessandro
- Russo Iris Shari
- Rutegård Martin
- Sabbatini Sonia
- Sabia Domenico
- Saeidi Sara
- Sahid Saidah
- Sahnan Kapil
- Sahnan Kapil
- Saladino Edoardo
- Salamea Juan C.
- Salido Andrea Jiménez
- Salimian Nick
- Salinas Roberto Paúl Andrade
- Saliu Fatmir
- Salvador Alan Francisco Alfaro
- Salvans Silvia
- Salvetti Francesco
- Samadov Elgun
- Sammartano Fabrizio
- Santocchi Pietro
- Santoliquido Matteo
- Santos Bárbara Ribeiro
- Saracoglu Can
- Saraiya Swapnil Mukesh
- Sarmiento Ray Inocencio
- Saroglu Azize
- Sartori Alberto
- Sasia Diego
- Saumtally Mohammad Saad
- Sánchez Tatiana Gómez
- Sánchez-Cabús Santiago
- Sánchez-Guillén Luis
- Sbacco Valentina
- Scabini Stefano
- Scaringi Stefano
- Scaringi Stefano
- Schena Carlo Alberto
- Schiavo Ciro
- Schiltz Boris
- Schizas Dimitrios
- Schlottmann Francisco
- Sciaudone Guido
- Scopelliti Michele
- Scotti Mauro Alessandro
- Scotti Mauro Alessandro
- Scotto Bruno
- Segura-Sampedro Juan J.
- Selvaggi Francesco
- Selvaggi Lucio
- Sensi Bruno
- Serena De Fatico Gilda
- Seretis Charalampos
- Sergeant Gregory
- Serrablo Alejandro
- Serradilla-Martín Mario
- Serrano-Navidad Monica
- Sevik Husnu
- Seyfried Steffen
- Shalaby Mostafa
- Shiferaw Desta
- Siagian Dumaria Ketty
- Sibaja-Matamoros Dauber A.
- Sica Giuseppe S.
- Sidiropoulou Zacharoula
- Silvestro Roberto
- Singares Eduardo Smith
- Singh-Ranger Gurpreet
- Siragusa Leandro
- Slesser Alistair A. P.
- Sliwinski Svenja Christin
- Smerieri Elia
- Smerieri Nazareno
- Soares Antonio S.
- Soldini Gabriele
- Sotiropoulou Maria
- Sotiropoulu Maria
- Souadka Amine
- Sousa Xavier
- Souza Hamilton Petry
- Spampinato Marcello Giuseppe
- Sparavigna Marco
- Spartalis Eleftherios
- Spartalis Michael
- Sperotto Beatrice
- Spiezio Giovanni
- Spoletini Gabriele
- Stecca Tommaso
- Stijns Jasper
- Stocco Alberto
- Stringfield Sarah Beth
- Stubbs Benjamin M.
- Subramaniam Ravichandran
- Supit Tommy
- Syed Syed Muhammad Ali
- Syn Nicholas L.
- Synekidou Eirini
- Tadesse Robel
- Taeme Mulugeta
- Taffese Abebe
- Takkenberg Marijn
- Tallon-Aguilar Luis
- Tamini Nicolò
- Tampaki Ekaterini Christina
- Tampakis Athanasios
- Tan Jessica J.
- Tan Jih Huei
- Tandoi Francesco
- Tantravahi Umasankar
- Tarallo Mariarita
- Tartaglia Nicola
- Tasselli Francesco Menegon
- Tasselli Francesco Menegon
- Tatar Cihad
- Tayeh Salim
- Taylor John Vincent
- Ted Tedla Gebretsadik
- Teddy Tewodros Abule Bilata
- Tegegn Ayenachew Getachew
- Tejedor Patricia
- Tekin Oguzhan
- Tellez Clara
- Tenconi Silvia Maria
- Tense Tadesse H.
- Tepelenis Kostas
- Teran Alfonso Ivan Sanchez
- Terés Lara Blanco
- Terwes Natasha Loria
- Tesfay Goytom Knfe
- Thambi Prem
- Tita Agustín
- Tolla Ashenafi Negash
- Tolonen Matti
- Tomada Elisa Paoluzzi
- Tomasicchio Giovanni
- Toscano Marta Jiménez
- Toti Johannes M. A.
- Travers Lawrence Albert Salter
- Tropeano Francesca Paola
- Tryliskyy Yegor
- Tsouknidas Ioannis
- Tufo Andrea
- Tur-Martinez Jaume
- Tur-Martinez Jaume
- Tura Marina Vila
- Turrado-Rodriguez Victor
- Turri Giulia
- Tutino Roberta
- Uccelli Matteo
- Uggeri Fabio
- Uzunoglu Mustafa Yener
- Uzzau Alessandro
- Uzzau Alessandro
- Vailas Michail
- Vailas Michail
- Valadez Michel Hernandez
- Valdivieso Xavier HGarcía
- Valinoti Agustín
- Van Doorn Berend
- van Ramshorst Gabrielle
- Vanerio Patricio
- Vannelli Alberto
- Vanni Gianluca
- Vanni Gianluca
- Varela Cristopher
- Varela Cristopher L.
- Vargas Luis Felipe Cabrera
- Vellei Samantha
- Verdi Daunia
- Veroux Massimiliano
- Veroux Massimiliano
- Vescio Francesca
- Vigorita Vincenzo
- Vilallonga Ramon
- Vincenzi Paolo
- Vinci Danilo
- Vinci Danilo
- Violante Tommaso
- Visag-Castillo Victor
- Voon Kelvin
- Walędziak Maciej
- Wani Ajaz
- Wani Ishfaq Ahmad
- Wani Rauf
- Wassie Chekol
- Wilkins Alex
- Wyroslak-Najs Justyna
- Yallew Gebeyaw Mengist
- Yang Wah
- Yildirim Ali Cihat
- Yildiz Ishak
- Yiu Andrew
- Yiu Andrew
- Younis Muhammad Umar
- Yusoff Ahmad Ramzi
- Zacharis Georgios
- Zafra David Ambrona
- Zaghloul Tarek M.
- Zambon Martina
- Zanus Giacomo
- Zarnescu Narcis Octavian
- Zeb Muhammad
- Zena Alemayehu Shanko
- Zerbo Domenico
- Zuchini Andrés Mendoza
- Zullo Alessia
- Publication venue
- Publication date
- 29/04/2024
- Field of study
: The workload of general surgeons is multifaceted, encompassing not only surgical procedures but also a myriad of other responsibilities. From April to May 2023, we conducted a CHERRIES-compliant internet-based survey analyzing clinical practice, academic engagement, and post-on-call rest. The questionnaire featured six sections with 35 questions. Statistical analysis used Chi-square tests, ANOVA, and logistic regression (SPSS® v. 28). The survey received a total of 1.046 responses (65.4%). Over 78.0% of responders came from Europe, 65.1% came from a general surgery unit; 92.8% of European and 87.5% of North American respondents were involved in research, compared to 71.7% in Africa. Europe led in publishing research studies (6.6 ± 8.6 yearly). Teaching involvement was high in North America (100%) and Africa (91.7%). Surgeons reported an average of 6.7 ± 4.9 on-call shifts per month, with European and North American surgeons experiencing 6.5 ± 4.9 and 7.8 ± 4.1 on-calls monthly, respectively. African surgeons had the highest on-call frequency (8.7 ± 6.1). Post-on-call, only 35.1% of respondents received a day off. Europeans were most likely (40%) to have a day off, while African surgeons were least likely (6.7%). On the adjusted multivariable analysis HDI (Human Development Index) (aOR 1.993) hospital capacity > 400 beds (aOR 2.423), working in a specialty surgery unit (aOR 2.087), and making the on-call in-house (aOR 5.446), significantly predicted the likelihood of having a day off after an on-call shift. Our study revealed critical insights into the disparities in workload, access to research, and professional opportunities for surgeons across different continents, underscored by the HDI
Personality disorders and Axis I comorbidity in adolescent outpatients with ADHD
- Author
- A Brasset-Grundy
- A Caspi
- A Caspi
- A Caspi
- A Dalteg
- A Fossati
- A Philipsen
- A Philipsen
- AE Skodol
- AM Chanen
- AM Chanen
- American Psychiatric Association
- American Psychiatric Association
- B Efron
- BE Johnson JG
- C Salavera
- CJ Miller
- CM Grilo
- CM Grilo
- D Cicchetti
- D Eich
- D Lader
- D Sheehan
- D Wetterborg
- DJ Feenstra
- DV Sheehan
- E Roysamb
- F Fruyt De
- F Levy
- FE Dijk van
- G Polanczyk
- G Polanczyk
- H Blaker
- Hans Ole Korsgaard
- J Staller
- JM Rey
- KW Lange
- L Montejano
- LA Adler
- LA Adler
- M Fischer
- M Kaess
- M Kongerslev
- M Kongerslev
- M Speranza
- M Zimmerman
- MC Zanarini
- MI Helgeland
- MI Helgeland
- MI Helgeland
- MK Singh
- N Kerekes
- NP Gosden
- P Prada
- Pfohl B BNZM
- R Vidal
- Randi Ulberg
- RC Kessler
- RC Kessler
- RL Shiner
- S Torgersen
- S Torgersen
- SL Smalley
- Svenn Torgersen
- TJ Trull
- Tore Wentzel-Larsen
- V Cramer
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
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- Publication venue
- Oxford University Press (OUP)
- Publication date
- 01/07/2023
- Field of study
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
- Author
- Abad-Motos Ane
- Abbas Ahmed M.
- Abbas Mostafa
- Abbasi Mujeeb
- Abbott Tom
- Abd Karim Muhammad Fairuz Shah
- Abdalaal Ibrahim
- Abdel-Galil Khalid
- Abdelemam Rania
- Abdelgawad Abdalrahman
- Abdelkarim Maryam
- Abdelkhalek Mohamed
- Abdelmageed Abdelfatah
- Abdelmawgoud Sherif
- Abdelmohsen Sarah
- Abdelrahman Ahmed Saber
- Abdelrahman Mostafa
- Abdelwahab Khaled
- Abdou Hossam
- Abdulai Darling Ramatu
- Abdulkhaleq Marwa
- Abdullah Bahiyah
- Abdulsalam Khalifa
- Abdulsalam Shuaib
- Abdur-Rahman Lukman
- Abdus-Salam Rukiyat
- Abdussalam Hameedat Opeyemi
- Abebrese John Tabiri
- Abeldaño Ariel
- Abou-Khalil Jad
- Abou-Taleb Hisham
- Abozid Anwaar
- Abozied Hesham
- Abrate Alberto
- Abu-Zaid Ahmed
- Abubakar Mohammed Kabir
- Abud Burçin
- Abuzaid Mohammed
- Adam Albushra Altayeb
- Adamina Michel
- Adamou Harissou
- Adamu Auwal
- Adamu Kabir Musa
- Adanu Kekeli
- Adebara Idowu
- Adebola Oluwaseyi
- Ademuyiwa Adesoji
- Adeniran Abiodun
- Adepiti Akinfolarin
- Aderogba Adeleke Akeem
- Adesunkanmi Abdulhafiz
- Adeyeye Ademola
- Adisa Adewale
- Adjeso Theophilus Justus Kofi
- Ads Adel Mohamed
- Ads Alaa Mohamed
- Adu-Aryee Nii Armah
- Adumah Collins
- Afzal Irrum
- Agapov Mikhail
- Agarwal Gaurav
- Agarwal Ravi
- Agbeko Anita Eseenam
- Agbeno Evans Kofi
- Agbonrofo Peter
- Agboola Oluseyi
- Aggarwal Gaurav
- Aghadi Ifeanyi
- Aghtarafi Natasha
- Agrawal Amit
- Agresta Ferdinando
- Aguado Héctor J.
- Aguilera-Arevalo Maria-Lorena
- Aherne Thomas
- Ahmad Aline
- Ahmad Maleeha
- Ahmad Misbahu
- Ahmad Sarwat
- Ahmad Shahzaib
- Ahmad Shoaib
- Ahmed Hayat Tarig Abdelhafiz
- Ahmed Khalid
- Ahmed Sharwany
- Ahmed Shima
- Ahmed Usama
- Aisuodionoe-Shadrach Oseremen
- Aitken Sarah
- Ajenifuja Kayode
- Ajiya Abdulrazak
- Akeel Nouf
- Akin Emrah
- Akinajo Opeyemi
- Akinyemi Tosin
- Akrida Ioanna
- Aktokmakyan Talar Vartanoglu
- Akwaisah Ayoub
- Al Bettar Osama
- Al-Badawi Ismail A.
- Al-Juaifari Maytham
- Al-Khyatt Waleed
- Al-Mallah Abdullah
- Al-Nusairi Ahmed
- Al-Saadi Nina
- Al-Sayaghi Khaled
- Al-Shaiji Tariq
- Al-Shehari Mohammed
- Al-Touny Aiman
- Al-Touny Shimaa A.
- Aladawi Omar
- Aladna Abdallah
- Alali Mahmoud
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- Alexander Philip
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- Algahtany Khaled
- Algarni Kamal
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- Alharmi Rawan A. Rahman
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- Ali Mohamed Shafi Mahboob
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- Allan Anna
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- Almhimid Ali
- Almiqlash Bushray
- Almoshantaf Mohammad Badr
- Almutairi Abdulmjeed
- Alnsour Abed Alfattah Mahmoud
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- Alonso Jesús Aarón Martínez
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- Sebai Amine
- Seeliger Barbara
- Seenivasagam Rajkumar Kottayasamy
- Segalini Edoardo
- Segaren Neil
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- Shah Vinay
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- Shoukrie Shoukrie I. M.
- Shrestha Rashmit
- Siboe Mark
- Sica Giuseppe
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- Singer Georg
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- Sleem Adham
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- Smith A.
- Smolle-Juettner Freyja-Maria
- Sodhai Vivek
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- Sokolov Manol
- Solaini Leonardo
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- Sole-Sedeno Josep M.
- Soljic Martina
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- Soon Wai Cheong
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- Sparavigna Marco
- Spartalis Michael
- Spellar Kayleigh
- Spiers Harry V. M.
- Spina Alfio
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- Squiers John
- Stabler Robert
- Stamatakis Emmanouil
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- Starr Nichole
- Stather Philip
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- Stevenson Andrew
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- Stijns Jasper
- Stogowski Piotr Tomasz
- Stoleriu Mircea Gabriel
- Stoyanov Vladislav
- Street John
- Strotmann Johanna Josefine
- Stroumpoulis Konstantinos
- Su Yu-Xiong
- Suarez Sara Busto
- Subramani Yamini
- Subramaniam Sentilnathan
- Sue-Chue-Lam Colin
- Suer Muhammed Salih
- Sulaiman Bilal
- Sultania Mahesh
- Sundarraju Shalini
- Sungurtekin Hulya
- Suresh Sreelakshmi
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- Swed Sarya
- Syllaios Athanasios
- Symeonidis Dimitrios
- Szabómihályová Katarína
- Szakmany Tamas
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- Szyluk Karol
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- Sánchez-Guillén Luis
- Süleyman Marlen
- Tadic Boris
- Taha Anas
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- Tailor Bhavesh
- Taj Eldeen Samaher Taj Eldeen Hassan
- Takeda Flavio Roberto
- Takkenberg Marijn
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- Tallon-Aguilar Luis
- Talwar Rishi
- Tamayo Beatriz Villota
- Tamburello Sara
- Tamini Nicolò
- Tammo Ömer
- Tamoos Khalil
- Tampaki Ekaterini Christina
- Tampakis Athanasios
- Tan Chih Ying
- Tan Shawn Jia Hwang
- Tanal Mert
- Tanas Yousef
- Tang Alethea
- Tang Yita
- Tani Sobhana Iftekhar
- Tantraworasin Apichat
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- Tapia-Herrero Ana-María
- Tarek Ahmed
- Tariq Aiman
- Tarle Marko
- Tarsitano Achille
- Tartaglia Dario
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- Tashkandi Wail
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- Tatar Cihad
- Tatsis Dimitris
- Tawalbeh Ra'Fat
- Tawiah Augustine
- Tebha Sameer
- Techapongsatorn Suphakarn
- Teixeira Pedro
- Tejero-Pintor Francisco J.
- Tellez Karla Susana Martin
- Tellez Luis Garcia-Sancho
- Thaha Mohamed Adhnan
- Thakar Sumit
- Thaw May Htoo
- Theivendran Kanthan
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- Theodoropoulos George
- Theophilidou Elena
- Thereska Dariel
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- Thomas Bradley
- Thomas Jerin Jose
- Thuduvage Vasanthika
- Thumbadoo Ruben
- Tian Sarah
- Tidjane Anisse
- Tirloni Luca
- Toia Francesca
- Tokidis Evripidis
- Tokocin Merve
- Tolani Musliu Adetola
- Toma Elena Adelina
- Tomasicchio Giovanni
- Tomlinson James
- Tonini Valeria
- Torre Beatrice
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- Tousidonis Manuel
- Trabulsi Nora
- Tranca Sebastian
- Trebol Jacobo
- Trejo-Avila Mario
- Triantafyllou Alexandra
- Triantafyllou Tania
- Trifunovski Aleksandar
- Tripathi Manjul
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- Trostchansky Ivan
- Trulson Alexander
- Trungu Sokol
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- Tsakiridis Ioannis
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- Tsoulfas Georgios
- Tucker Olga
- Tuech Jean Jacques
- Turan Alparslan
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- Ulas Ali Bilal
- Uldry Emilie
- Ulgur Hanife Seyda
- Ulkucu Attila
- Ulman Elif Akbas
- Ulman Hilmican
- Ulutaş Mehmet Eşref
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- Unsworth Richard
- Uprak Tevfik Kivilcim
- Urriza Pablo Vallés
- Usman Muhammad
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- Van Goor Harry
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- Vas Aurelia
- Vasarhelyi Edward
- Vaschetti Roberto
- Vassiliu Panteleimon
- Vatansever Dogan
- Vatish Jamie
- Vaughan-Shaw Peter G.
- Vaysburg Dennis
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- Velten Markus
- Velázquez Maria Jose Martinez
- Venkatappa Sunil Kumar
- Venketeswaran Meenakshi
- Venskutonis Donatas
- Verbic Milena Senica
- Verdi Daunia
- Vergara-Fernandez Omar
- Verhoeff Kevin
- Veroux Massimiliano
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- Verre Luigi
- Vida Lucian
- Vidya Raghavan
- Viglietta Edoardo
- Vijay Vardhini
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- Vilaró Blanca Capdevila
- Villanueva Julio
- Vilz Tim O.
- Vincent Elizabeth
- Vinci Danilo
- Viola Simona
- Violante Tommaso
- Vishnoi Jeewan Ram
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- Vivancos Laura Guillamon
- Vives Josep Maria Muñoz
- Vizzielli Giuseppe
- Vohra Lubna
- Vokshi Ismail
- Vosinakis Christos
- Vásquez Javier Alberto Gutiérrez
- Vázquez Gil
- Vázquez Irene Ortega
- Vǎcǎraşu Andrei Bogdan
- Wade Ryckie
- Wafi Omar
- Wagner Gabriela
- Wallis Christopher
- Wanjara Samuel
- Waqar Shahzad Hussain
- Warden Claire
- Warner Christian
- Wasim D.
- Wason Shaun
- Wasserman Isaac
- Watcyn-Jones Tom
- Waterson Ben
- Watson David
- Watson Matthew
- Weber Clemens
- Wheatstone P.
- Wheeler James
- Wheldon Luke
- White Michelle
- White Stuart
- White William
- Wickramasinghe Dakshitha
- Widmer Lukas Werner
- Wiedemann Dominik
- Wiesinger Clemens Georg
- Wijekoon Naveen
- Wijenayake Wasantha
- Wijeyaratne Manuk
- Wijeysundera Duminda
- Wiles Matthew
- Wilkin Richard
- Wilkins Alex
- Wilkins James
- William Tinka George
- Williams Omolara Modupe
- Williams Shekinah
- Windsor John
- Winnand Philipp
- Wittmann Maria
- Wolde Amanuel
- Wolfenden John W. D.
- Wong Benjamin Ngie Xiong
- Wong Enoch
- Wong Evan G.
- Wong George Kwok Chu
- Wong Ho Ying Flora
- Wong Kai Yuen
- Wormald Justin
- Wright Deborah
- Wright Joshua
- Wu Fiona
- Wurm Markus
- Xenaki Sofia
- Yadev Ip
- Yahaya Ahmad Shuib
- Yakubu Mustapha
- Yang Wah
- Yanik Özge
- Yanowsky-Reyes Guillermo
- Yassin Abubaker
- Yates Elizabeth
- Yebes Alvaro
- Yenli Edwin Mwintiereh Ta-Ang
- Yeoh Tien
- Yeung Justin
- Yiallourou Anneza
- Yigit Banu
- Yildirim Asif
- Yim Guang
- Yiu Andrew
- Yonekura Hiroshi
- Yotsov Tsanko
- Younis Muhammad Umar
- Yunus Alif
- Yusefi Hossein
- Zabaleta Jon
- Zabkiewicz Catheriner
- Zaccaria Giulia
- Zacharia Bincy
- Zafar Syed Nabeel
- Zago Mauro
- Zaheen Zakia
- Zahid Zahra
- Zaimis Tilemachos
- Zakaria Andee Dzulkarnaen
- Zambon Martina
- Zamora Lindsey
- Zampogna Biagio
- Zancana Giuseppa
- Zani Augusto
- Zanin Luca
- Zanini Nicola
- Zapardiel Ignacio
- Zapata Carlos Shiraishi
- Zarif Pierre
- Zaránd Attila
- Zehnder Philipp
- Zenger Serkan
- Zenha Horácio
- Zhu Michael Z. L.
- Ziemann Sebastian
- Zimak Danijela Mrazovac
- Zimak Zoran
- Zivkovic Dragana
- Zizzo Maurizio
- Zucker Benjamin
- Zwain Yasir
- Zyskowski Michael
- Ávila Clara Castro
- Älgå Andreas
- Çakici Mehmet Çaǧlar
- Çelik Enes
- Çelik Meryem Nur
- Özçay Necdet
- Şevik Hüsnü
- Šantak Goran
- Šimko Kristián
- Žatecký Jan
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2023
- Field of study
Abstract
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
Scaling and spatial dynamics in plant–pathogen systems: from individuals to populations
- Publication venue
- 'The Royal Society'
- Publication date
- Field of study
Resilience in the European Union external action
- Author
- A Howell
- A Howell
- A Juncos
- ALNAP
- B Evans
- B Evans
- C Aradau
- C Aradau
- D Bulley
- D Chandler
- D Chandler
- D Chandler
- D Chandler
- D Chandler
- D Hilhorst
- E Cusumano
- F Lentzos
- HWJ Rittel
- I Manners
- J Brasset
- J Brasset
- J Coaffee
- J Coaffee
- J Coaffee
- J Coaffee
- J Joseph
- J Joseph
- J Pospisil
- J Reid
- J Ryan
- J Schmidt
- J Walker
- M Duffield
- M Duffield
- M Kaufmann
- MD Cavelty
- N Tocci
- N Tocci
- P Bourbeau
- P Bourbeau
- P O’Malley
- P Rogers
- R Paris
- R Paris
- S Flynn
- S Walklate
- V Jennison
- W Wagner
- Publication venue
- Palgrave
- Publication date
- 01/01/2020
- Field of study
Epigenetic Research in Cancer Epidemiology: Trends, Opportunities, and Challenges
- Author
- Publication venue
- 'American Association for Cancer Research (AACR)'
- Publication date
- 01/01/1869
- Field of study
general view, located in Highland Park in the Fort Hill neighborhood, 198