Matter, material, architecture. The tectonic conception between spontaneous consciousness and critical consciousness

[EN] Talking about of place and matter as indissoluble terms of architectural practice could at first appear tautological, because of the essential link that makes them participating in the construction of anthropic structures. But nowadays it has become of utmost importance to emphasize it, in the light of the profound changes that concern the architecture in the last decades, during which the importance of technology as a value in itself that summarizes all the meanings of the project has questioned the link always existed among materials, building and language, as expression of a type-morphological world in which to recognize themselves collectively. In this sense it may be useful to analyze some nodal points characterizing developments and discontinuities of this relationship, to investigate the role of memory as a "working theme" of architecture, performed above all through materials, and to highlight the importance to seek a critical link between place and type read in the ontological dimension of the building, that has no nostalgic or historiographical purpose, but on the contrary it is necessary to root the project into a cultural palimpsest that allows the present of construction to be dense of social meanings.Rociola, GF. (2017). Matter, material, architecture. The tectonic conception between spontaneous consciousness and critical consciousness. VITRUVIO - International Journal of Architectural Technology and Sustainability. 2(2):35-53. doi:10.4995/vitruvio-ijats.2017.8745SWORD355322Borsi F., Leon Battista Alberti : Opera completa, Electa, Milano, pp. 221-224. 1973.Brandi C., Teoria del restauro, Einaudi, Torino, p. 45. 1977.Carpenter R., Gli architetti del Partenone, Giulio Einaudi Editore, Torino, pp. 84-85. 1979.Di Stefano E., L'altro sapere : Bello, Arte, Immagine in Leon Battista Alberti, Centro Internazionale Studi di Estetica, Palermo, p. 18. 2000.Frampton K., Storia dell'architettura moderna, Zanichelli Editore, Bologna, pp. 124-125. 1982.Frampton K., Tettonica e architettura : Poetica della forma architettonica nel XIX e XX secolo, Skira, Milano, pp. 21-22. 1999.Gregotti V., Dentro l'architettura, Bollati Boringhieri, Torino, p. 56. 1991.Martin R., Architettura Greca, Electa, Milano, pp. 36-38. 1977.Middleton R., La tradizione razionalista in Francia. In: Middleton R. e Watkin D., Architettura : Ottocento, Electa, Milano, p. 8. 1977.Mies van der Rohe L., Gli scritti e le parole, edited by Pizzigoni V., Piccola Biblioteca Einaudi, p. 8. 2010.Muratori S., Architettura e civiltà in crisi, Centro Studi di Storia Urbanistica, Roma, p. 11. 1963.Purini F., Comporre l'architettura, Editori Laterza, Roma-Bari, p. 93. 2000.Strappa G., Unità dell'organismo architettonico : Note sulla formazione e trasformazione dei caratteri degli edifici, Dedalo, Bari, 1995, pp. 53-64Summerson J., Il linguaggio classico dell'architettura, Giulio Einaudi Editore, Torino, 1970, p. 32Wittkower R., Principî architettonici nell'età dell'Umanesimo, Giulio Einaudi Editore, Torino, 1964, pp. 37-4

The immunological basis of tumor therapy by targeted delivery of TNFa to tumor vessels

ISSN:1742-469

Cardiovascular Post-Acute COVID-19 Syndrome: Definition, Clinical Scenarios, Diagnosis, and Management

Post-acute COVID-19 syndrome (PACS) describes the clinical condition of some SARS-CoV-2-infected patients in which a wide range of signs and symptoms that persist for several months after the acute phase of the disease. Cardiovascular symptoms including chest pain, dyspnea, elevated blood pressure, palpitations, inappropriate tachycardia, fatigue, and exercise intolerance are common in this condition. Some infected patients develop cardiovascular diseases such as myocarditis, pericarditis, new or worsening myocardial ischemia due to obstructive coronary artery disease, microvascular dysfunction, stress cardiomyopathy, thromboembolism, cardiovascular sequelae of pulmonary disease, arrhythmias, while others have cardiovascular symptoms without objective evidence of cardiovascular abnormalities. In the present chapter, definition, spectrum of manifestations, clinical scenarios, diagnosis, management, and therapy of cardiovascular PACS will be discussed

Contrasting styles of (U)HP rock exhumation along the Cenozoic Adria-Europe plate boundary (Western Alps, Calabria, Corsica)

Since the first discovery of ultrahigh pressure (UHP) rocks 30 years ago in the Western Alps, the mechanisms for exhumation of (U)HP terranes worldwide are still debated. In the western Mediterranean, the presently accepted model of synconvergent exhumation (e.g., the channel-flow model) is in conflict with parts of the geologic record. We synthesize regional geologic data and present alternative exhumation mechanisms that consider the role of divergence within subduction zones. These mechanisms, i.e., (i) the motion of the upper plate away from the trench and (ii) the rollback of the lower plate, are discussed in detail with particular reference to the Cenozoic Adria-Europe plate boundary, and along three different transects (Western Alps, Calabria-Sardinia, and Corsica-Northern Apennines). In the Western Alps, (U)HP rocks were exhumed from the greatest depth at the rear of the accretionary wedge during motion of the upper plate away from the trench. Exhumation was extremely fast, and associated with very low geothermal gradients. In Calabria, HP rocks were exhumed from shallower depths and at lower rates during rollback of the Adriatic plate, with repeated exhumation pulses progressively younging toward the foreland. Both mechanisms were active to create boundary divergence along the Corsica-Northern Apennines transect, where European southeastward subduction was progressively replaced along strike by Adriatic northwestward subduction. The tectonic scenario depicted for the Western Alps trench during Eocene exhumation of (U)HP rocks correlates well with present-day eastern Papua New Guinea, which is presented as a modern analog of the Paleogene Adria-Europe plate boundary