A High Reliability Gas-driven Helium Cryogenic Centrifugal Compressor

A helium cryogenic compressor was developed and tested in real conditions in 1996. The achieved objective was to compress 0.018 kg/s Helium at 4 K @ 1000 Pa (10 mbar) up to 3000 Pa (30 mbar). This project was an opportunity to develop and test an interesting new concept in view of future needs. The main features of this new specific technology are described. Particular attention is paid to the gas bearing supported rotor and to the pneumatic driver. Trade off between existing technologies and the present work are presented with special stress on the bearing system and the driver. The advantages are discussed, essentially focused on life time and high reliability without maintenance as well as non pollution characteristic. Practical operational modes are also described together with the experimental performances of the compressor. The article concludes with a brief outlook of future work

Методические особенности управления туристскими потоками в регионе (на примере Автономной Республики Крым)

Экономическая жизнь, начиная от простых жителей сел и городов, до экономики полуострова в целом зависит от количества туристов, приехавших в Крым на отдых и лечениеЕкономічне життя, починаючи від простих мешканців сіл і міст, до економіки півострова в цілому залежить від кількості туристів, що приїхали до Криму на відпочинок і лікуванн

Consideration of the Mechanisms for Tidal Bore Formation in an Idealized Planform Geometry

A tidal bore is a positive wave traveling upstream along the estuary of a river, generated by a relatively rapid rise of the tide, often enhanced by the funneling shape of the estuary. The swell produced by the tide grows and its front steepens as the flooding tide advances inland, promoting the formation of a sharp front wave, i.e., the tidal bore. Because of the many mechanisms and conditions involved in the process, it is difficult to formulate an effective criterion to predict the bore formation. In this preliminary analysis, aimed at bringing out the main processes and parameters that control tidal bore formation, the degrees of freedom of the problem are largely reduced by considering a rectangular channel of constant width with uniform flow, forced downstream by rising the water level at a constant rate. The framework used in this study is extremely simple, yet the problem is still complex and the solution is far from being trivial. From the results of numerical simulations, three distinctive behaviors emerged related to conditions in which a tidal bore forms, a tidal bore does not form, and a weak bore forms; the latter has a weakly steep front and after the bore formed it rapidly vanishes. Based on these behaviors, some criteria to predict the bore formation are proposed and discussed. The more effective criterion, suitably rearranged, is checked against data from real estuaries and the predictions are found to compare favorably with the available data

A splitting approach for the fully nonlinear and weakly dispersive Green-Naghdi model

The fully nonlinear and weakly dispersive Green-Naghdi model for shallow water waves of large amplitude is studied. The original model is first recast under a new formulation more suitable for numerical resolution. An hybrid finite volume and finite difference splitting approach is then proposed. The hyperbolic part of the equations is handled with a high-order finite volume scheme allowing for breaking waves and dry areas. The dispersive part is treated with a classical finite difference approach. Extensive numerical validations are then performed in one horizontal dimension, relying both on analytical solutions and experimental data. The results show that our approach gives a good account of all the processes of wave transformation in coastal areas: shoaling, wave breaking and run-up

Barred-beach morphological control on infragravity motion

A conceptual analysis of the coupling between bars and infragravity waves is performed combining laboratory experiments and numerical modeling. Experiments are carried out in a wave flume with a barred profile. The Boussinesq fully-nonlinear model SERR1D is validated with the laboratory data and a sensitivity analysis is performed next to study the influence on the infragravity wave dynamics of bar amplitude and location, and swash zone slope. A novel technique of incident and reflected motions separation that conserves temporal characteristics is applied. We observe that changing bar characteristics induces substantial variations in trapped energy. Interestingly, a modification of swash zone slope has a large influence on the reflected component, controlling amplitude and phase time-lag, and consequently on the resonant pattern. Variations of trapped infragravity energy induced by changes of swash zone slope reach 25 %. These changes in infragravity pattern consequently affect short-wave dynamics by modifying the breakpoint location and the breaking intensity. Our conceptual investigation suggests the existence of a morphological feedback through the action of evolving morphology on infragravity structures which modulates the action of short-waves on the morphology itself

Field Observations of Wave-induced Headland Rips

Mouragues, A.; Bonneton, P.; Castelle, B.; Marieu, V.; Barrett, A.; Bonneton, N.; Detand, G.; Martins, K.; McCarroll, J.; Morichon, D.; Poate, T.; Rodriguez Padilla, I.; Scott, T., and Sous, D., 2020. Field observations of wave-induced headland rips. In: Malvárez, G. and Navas, F. (eds.), Global Coastal Issues of 2020. Journal of Coastal Research, Special Issue No. 95, pp. 578-582. Coconut Creek (Florida), ISSN 0749-0208. Most of rip-current field experiments have focused on persistent rips along rip-channeled sandy beaches or transient rips along reasonably alongshore-uniform surf-zone morphology, while experiments on rip flowing against structures are scarce. In October 2018, a 3-week field experiment was performed at Anglet beach, SW France, aiming at examining the dynamics of high-energy rip currents in complex settings. The beach is barred with prominent inherited geology, characterized by the presence of a 500-m headland and a natural submerged reef. A large array of in-situ instruments was deployed to capture the temporal and spatial variability of rip flow circulations, including ADCPs, surf-zone drifters and video monitoring. The latter allowed to identify a wide range of rip-flow patterns. Among these patterns, a high-intensity rip current flowing against the headland was a dominant feature for obliquely incident waves. Such a boundary rip current was driven by the deflection of the longshore current against the headland, peaking at 0.7 m/s (5-min time- and depth-averaged) 800-m offshore in 12-m depth for a moderate storm event with 4-m obliquely incident waves. Very-low-frequency (O(1h) and O(30min)) fluctuations of this rip current were observed around low tide. Measurements of the vertical structure of the rip reveal that the deflection rip was more vertically-sheared as the water depth increases, with higher velocities near the surface, which is typical of a theoretical rip head structure

High‐Energy Surf Zone Currents and Headland Rips at a Geologically Constrained Mesotidal Beach

International audienceWe analyze Eulerian and Lagrangian measurements of wave-induced circulation collected during a 3-week field experiment at a high-energy mesotidal barred beach with the presence of a 500-m headland and a submerged reef. Small changes in wave and tide conditions were found to largely impact circulation patterns. Three main regimes were identified depending on offshore wave obliquity: (1) Under shore-normal configuration, the flow was dominated by cross-shore motions, except for moderate waves at low tide, with the presence of a quasi-steady circulation cell on the reef. (2) Under shadowed configuration, an onshore-directed current flowing away from the headland and a weak oscillating eddy were present outside and inside the shadow region, respectively. (3) Under deflection configuration, a deflection rip flowing against the headland and extending well beyond the surf zone was present, with activity maximized around low tide for moderate waves. Under 4-m oblique waves, the deflection rip was active regardless of the tide with mean depth-averaged velocities up to 0.7 m/s 800-m offshore in 12-m depth, with energetic low-frequency fluctuations. Our results emphasize the ability of deflection rips to transport materials far offshore, suggesting that such rips can transport sediment beyond the depth of closure. This study indicates that a wide variety of wave-driven circulation patterns can occur and sometimes coexist on beaches with prominent geological settings. Changes in the dominant driving mechanism can occur as a result of small changes in wave and tide conditions, resulting in more spatially and temporally variable circulation than along open sandy beaches. Plain Language Summary Most field experiments about wave-induced circulation patterns have been conducted along open sandy beaches, while experiments in geologically constrained environments are scarce. We performed intensive field measurements at a high-energy beach with the presence of a 500-m headland and a submerged natural reef. Three main circulation patterns were identified depending on the offshore wave obliquity. For shore-normal waves, cross-shore motions dominated the nearshore region, while oblique wave configurations resulted in more complex horizontal circulation. In particular, under intense headland-directed longshore current, the flow was deflected seaward against the headland. This deflection resulted in an intense seaward flowing jet (deflection rip) extending well beyond the surf zone edge, particularly during storm conditions. Such findings highlight the ability of these deflection rips to dominate water and sediment exchanges between the nearshore and the inner shelf region. Our study further outlines the more spatially and temporally variable circulation patterns occurring along geologically constrained beaches compared to open sandy beaches, ranging from small recirculating cells across the reef to a large deflection rip extending hundreds of meters beyond the surf zone

The nuclear receptors of Biomphalaria glabrata and Lottia gigantea: Implications for developing new model organisms

© 2015 Kaur et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are creditedNuclear receptors (NRs) are transcription regulators involved in an array of diverse physiological functions including key roles in endocrine and metabolic function. The aim of this study was to identify nuclear receptors in the fully sequenced genome of the gastropod snail, Biomphalaria glabrata, intermediate host for Schistosoma mansoni and compare these to known vertebrate NRs, with a view to assessing the snail's potential as a invertebrate model organism for endocrine function, both as a prospective new test organism and to elucidate the fundamental genetic and mechanistic causes of disease. For comparative purposes, the genome of a second gastropod, the owl limpet, Lottia gigantea was also investigated for nuclear receptors. Thirty-nine and thirty-three putative NRs were identified from the B. glabrata and L. gigantea genomes respectively, based on the presence of a conserved DNA-binding domain and/or ligand-binding domain. Nuclear receptor transcript expression was confirmed and sequences were subjected to a comparative phylogenetic analysis, which demonstrated that these molluscs have representatives of all the major NR subfamilies (1-6). Many of the identified NRs are conserved between vertebrates and invertebrates, however differences exist, most notably, the absence of receptors of Group 3C, which includes some of the vertebrate endocrine hormone targets. The mollusc genomes also contain NR homologues that are present in insects and nematodes but not in vertebrates, such as Group 1J (HR48/DAF12/HR96). The identification of many shared receptors between humans and molluscs indicates the potential for molluscs as model organisms; however the absence of several steroid hormone receptors indicates snail endocrine systems are fundamentally different.The National Centre for the Replacement, Refinement and Reduction of Animals in Research, Grant Ref:G0900802 to CSJ, LRN, SJ & EJR [www.nc3rs.org.uk]

Molecular Evolution of Ultraspiracle Protein (USP/RXR) in Insects

Ultraspiracle protein/retinoid X receptor (USP/RXR) is a nuclear receptor and transcription factor which is an essential component of a heterodimeric receptor complex with the ecdysone receptor (EcR). In insects this complex binds ecdysteroids and plays an important role in the regulation of growth, development, metamorphosis and reproduction. In some holometabolous insects, including Lepidoptera and Diptera, USP/RXR is thought to have experienced several important shifts in function. These include the acquisition of novel ligand-binding properties and an expanded dimerization interface with EcR. In light of these recent hypotheses, we implemented codon-based likelihood methods to investigate if the proposed shifts in function are reflected in changes in site-specific evolutionary rates across functional and structural motifs in insect USP/RXR sequences, and if there is any evidence for positive selection at functionally important sites. Our results reveal evidence of positive selection acting on sites within the loop connecting helices H1 and H3, the ligand-binding pocket, and the dimer interface in the holometabolous lineage leading to the Lepidoptera/Diptera/Trichoptera. Similar analyses conducted using EcR sequences did not indicate positive selection. However, analyses allowing for variation across sites demonstrated elevated non-synonymous/synonymous rate ratios (dN/dS), suggesting relaxed constraint, within the dimerization interface of both USP/RXR and EcR as well as within the coactivator binding groove and helix H12 of USP/RXR. Since the above methods are based on the assumption that dS is constant among sites, we also used more recent models which relax this assumption and obtained results consistent with traditional random-sites models. Overall our findings support the evolution of novel function in USP/RXR of more derived holometabolous insects, and are consistent with shifts in structure and function which may have increased USP/RXR reliance on EcR for cofactor recruitment. Moreover, these findings raise important questions regarding hypotheses which suggest the independent activation of USP/RXR by its own ligand