Search for transient ultralight dark matter signatures with networks of precision measurement devices using a Bayesian statistics method

We analyze the prospects of employing a distributed global network of precision measurement devices as a dark matter and exotic physics observatory. In particular, we consider the atomic clocks of the Global Positioning System (GPS), consisting of a constellation of 32 medium-Earth orbit satellites equipped with either Cs or Rb microwave clocks and a number of Earth-based receiver stations, some of which employ highly-stable H-maser atomic clocks. High-accuracy timing data is available for almost two decades. By analyzing the satellite and terrestrial atomic clock data, it is possible to search for transient signatures of exotic physics, such as "clumpy" dark matter and dark energy, effectively transforming the GPS constellation into a 50,000km aperture sensor array. Here we characterize the noise of the GPS satellite atomic clocks, describe the search method based on Bayesian statistics, and test the method using simulated clock data. We present the projected discovery reach using our method, and demonstrate that it can surpass the existing constrains by several order of magnitude for certain models. Our method is not limited in scope to GPS or atomic clock networks, and can also be applied to other networks of precision measurement devices.Comment: See also Supplementary Information located in ancillary file

Assessing the Impact of Vertical Land Motion on Twentieth Century Global Mean Sea Level Estimates

Near-global and continuous measurements from satellite altimetry have provided accurate estimates of global mean sea level in the past two decades. Extending these estimates further into the past is a challenge using the historical tide gauge records. Not only is sampling nonuniform in both space and time, but tide gauges are also affected by vertical land motion (VLM) that creates a relative sea level change not representative of ocean variability. To allow for comparisons to the satellite altimetry estimated global mean sea level (GMSL), typically the tide gauges are corrected using glacial isostatic adjustment (GIA) models. This approach, however, does not correct other sources of VLM that remain in the tide gauge record. Here we compare Global Positioning System (GPS) VLM estimates at the tide gauge locations to VLM estimates from GIA models, and assess the influence of non-GIA-related VLM on GMSL estimates. We find that the tide gauges, on average, are experiencing positive VLM (i.e., uplift) after removing the known effect of GIA, resulting in an increase of 0.24 ± 0.08 mm yr−1 in GMSL trend estimates from 1900 to present when using GPS-based corrections. While this result is likely dependent on the subset of tide gauges used and the actual corrections used, it does suggest that non-GIA VLM plays a significant role in twentieth century estimates of GMSL. Given the relatively short GPS records used to obtain these VLM estimates, we also estimate the uncertainty in the GMSL trend that results from limited knowledge of non-GIA-related VLM

A study of atmospheric neutrinos with the IMB detector

A sample of 401 contained neutrino interactions collected in the 3300 metric ton fiducial mass IMB detector was used to study neutrino oscillations, geomagnetic modulation of the flux and to search for point sources. The majority of these events are attributed to neutrino interactions. For the most part, these neutrinos are believed to originate as tertiary products of cosmic ray interactions in the atmosphere. The neutrinos are a mixture of v sub e and v sub micron

Exploring the use of new school buildings through post-occupancy evaluation and participatory action research

This paper presents the results of the development and testing of an integrated post-occupancy evaluation (POE) approach for teachers, staff, pupils and community members using newly constructed school buildings. It focusses on three cases of UK secondary schools, demonstrating how users can be inspired to engage with the problems of school design and energy use awareness. The cases provided new insights into the engagement of school teachers, staff and young people regarding issues of sustainability, management, functional performance and comfort. The integrative approach adopted in these cases provided a more holistic understanding of these buildings’ performance than could have been achieved by either observational or more traditional questionnaire-based methods. Moreover, the whole-school approach, involving children in POE, provided researchers with highly contextualised information about how a school is used, how to improve the quality of school experiences (both socially and educationally) and how the school community is contributing to the building's energy performance. These POE methods also provided unique opportunities for children to examine the social and cultural factors impeding the adoption of energy-conscious and sustainable behaviours

An enhanced integrated water vapour dataset from more than 10 000 global ground-based GPS stations in 2020

We developed a high-quality global integrated water vapour (IWV) dataset from 12 552 ground-based global positioning system (GPS) stations in 2020. It consists of 5 min GPS IWV estimates with a total number of 1 093 591 492 data points. The completeness rates of the IWV estimates are higher than 95 % at 7253 (58 %) stations. The dataset is an enhanced version of the existing operational GPS IWV dataset provided by the Nevada Geodetic Laboratory (NGL). The enhancement is reached by employing accurate meteorological information from the fifth generation of European ReAnalysis (ERA5) for the GPS IWV retrieval with a significantly higher spatiotemporal resolution. A dedicated data screening algorithm is also implemented. The GPS IWV dataset has a good agreement with in situ radiosonde observations at 182 collocated stations worldwide. The IWV biases are within ±3.0 kg m−2 with a mean absolute bias (MAB) value of 0.69 kg m−2. The standard deviations (SD) of IWV differences are no larger than 3.4 kg m−2. In addition, the enhanced IWV product shows substantial improvements compared to NGL\u27s operational version, and it is thus recommended for high-accuracy applications, such as research of extreme weather events and diurnal variations of IWV and intercomparisons with other IWV retrieval techniques. Taking the radiosonde-derived IWV as reference, the MAB and SD of IWV differences are reduced by 19.5 % and 6.2 % on average, respectively. The number of unrealistic negative GPS IWV estimates is also substantially reduced by 92.4 % owing to the accurate zenith hydrostatic delay (ZHD) derived by ERA5. The dataset is available at https://doi.org/10.5281/zenodo.6973528 (Yuan et al., 2022)

Improved estimate of the policy-relevant background ozone in the United States using the GEOS-Chem global model with 1/2° × 2/3° horizontal resolution over North America

The policy-relevant background (PRB) ozone is defined by the US Environmental Protection Agency (EPA) as the surface ozone concentration that would be present over the US in the absence of North American anthropogenic emissions. It is intended to provide a baseline for risk and exposure assessments used in setting the National Ambient Air Quality Standard (NAAQS). We present here three-year statistics (2006–2008) of PRB ozone over the US calculated using the GEOS-Chem global 3-D model of atmospheric composition with 1/2° × 2/3° horizontal resolution over North America and adjacent oceans (2° × 2.5° for the rest of the world). We also provide estimates of the US background (no anthropogenic US emissions) and natural background (no anthropogenic emissions worldwide and pre-industrial methane). Our work improves on previous GEOS-Chem PRB estimates through the use of higher model resolution, 3-year statistics, better representation of stratospheric influence, and updated emissions. PRB is particularly high in the intermountain West due to high elevation, arid terrain, and large-scale subsidence. We present for this region a detailed model evaluation showing that the model is successful in reproducing ozone exceedances up to 70 ppbv. However, the model cannot reproduce PRB-relevant exceptional events associated with wildfires or stratospheric intrusions. The mean PRB estimates for spring–summer are 27 ± 8 ppbv at low-altitude sites and 40 ± 7 ppbv at high-altitude sites. Differences between the PRB simulation and the natural simulation indicate a mean enhancement from intercontinental pollution and anthropogenic methane of 9 ppbv at low-altitude sites and 13 ppbv at high-altitude sites. The PRB is higher than average when ozone exceeds 60 ppbv, particularly in the intermountain West. Our PRB estimates are on average 4 ppbv higher than previous GEOS-Chem studies and we attribute this to higher lighting, increasing Asian emissions, and improved model resolution. Whereas previous studies found no occurrences of PRB exceeding 60 ppbv, we find here some occurrences in the intermountain West. The annual 4th-highest PRB values in the intermountain West are typically 50–60 ppbv, as compared to 35–45 ppbv in the East or on the West Coast. Such high PRB values in the intermountain West suggest that special consideration of this region may be needed if the ozone NAAQS is decreased to a value in the 60–70 ppbv range.Earth and Planetary SciencesEngineering and Applied Science

An assessment of static Precise Point Positioning using GPS only, GLONASS only, and GPS plus GLONASS

The aim of this paper is to look into the achievable repeatability and accuracy from Precise Point Positioning (PPP) daily solutions when using GPS only (PPP GPS), GLONASS only (PPP GLO), and GPS plus GLONASS (PPP GPS+GLO) for static positioning. As part of the assessment, a comparison with global double difference (DD) GPS daily solutions is presented. It is shown, therefore, that all of the PPP daily solutions can achieve millimetric level repeatability, similar to the global DD GPS solutions. Furthermore, the mean of the biases between the PPP daily solutions and the global DD GPS daily solutions are constellation type dependent, while an improvement is found in the vertical component for PPP GPS+GLO over PPP GLO, as the latter may be more affected by any imperfections in the models for GLONASS antenna phase centre variations. It is concluded that PPP GLO daily solutions have the ability to be used as independent solutions to PPP GPS daily solutions for static positioning, and as an alternative to PPP GPS+GLO or global DD GPS daily solutions

Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing

Background: The presence of histone 3 lysine 9 (H3K9) methylation on the mouse inactive X chromosome has been controversial over the last 15 years, and the functional role of H3K9 methylation in X chromosome inactivation in any species has remained largely unexplored. Results: Here we report the first genomic analysis of H3K9 di- and tri-methylation on the inactive X: we find they are enriched at the intergenic, gene poor regions of the inactive X, interspersed between H3K27 tri-methylation domains found in the gene dense regions. Although H3K9 methylation is predominantly non-genic, we find that depletion of H3K9 methylation via depletion of H3K9 methyltransferase Set domain bifurcated 1 (Setdb1) during the establishment of X inactivation, results in failure of silencing for around 150 genes on the inactive X. By contrast, we find a very minor role for Setdb1-mediated H3K9 methylation once X inactivation is fully established. In addition to failed gene silencing, we observed a specific failure to silence X-linked long-terminal repeat class repetitive elements. Conclusions: Here we have shown that H3K9 methylation clearly marks the murine inactive X chromosome. The role of this mark is most apparent during the establishment phase of gene silencing, with a more muted effect on maintenance of the silent state. Based on our data, we hypothesise that Setdb1-mediated H3K9 methylation plays a role in epigenetic silencing of the inactive X via silencing of the repeats, which itself facilitates gene silencing through alterations to the conformation of the whole inactive X chromosome.Andrew Keniry, Linden J. Gearing, Natasha Jansz, Joy Liu, Aliaksei Z. Holik, Peter F. Hickey, Sarah A. Kinkel, Darcy L. Moore, Kelsey Breslin, Kelan Chen, Ruijie Liu, Catherine Phillips, Miha Pakusch, Christine Biben, Julie M. Sheridan, Benjamin T. Kile, Catherine Carmichael, Matthew E. Ritchie, Douglas J. Hilton and Marnie E. Blewit

De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development

Bosma arhinia microphthalmia syndrome (BAMS) is an extremely rare and striking condition characterized by complete absence of the nose with or without ocular defects. We report here that missense mutations in the epigenetic regulator SMCHD1 mapping to the extended ATPase domain of the encoded protein cause BAMS in all 14 cases studied. All mutations were de novo where parental DNA was available. Biochemical tests and in vivo assays in Xenopus laevis embryos suggest that these mutations may behave as gain-of-function alleles. This finding is in contrast to the loss-of-function mutations in SMCHD1 that have been associated with facioscapulohumeral muscular dystrophy (FSHD) type 2. Our results establish SMCHD1 as a key player in nasal development and provide biochemical insight into its enzymatic function that may be exploited for development of therapeutics for FSHD