FIRST RECORD OF CANTHARELLUS MINOR IN VIETNAM

This species of mushroom with orange fruiting bodies and yellow flesh grows in clumps on the forest land in the coordinates 11o56'34.45" N, 108o28'33.56" E in the pine (Pinus kesiya) forest, Da Lat City, Lam Dong Province, Vietnam. The results of analysis on the morphology, both macro- and micro-morphological characteristics of this mushroom showed that, pileus: 5-15 mm wide, infundibuliform; yellowish to orange; margin incurred, wavy-liked margin, non-striate; Pileus surface: smooth, scaleless, yellowish; Lamellae: distant, decurrent, not intervenose, concolorous to pileus; Context: concolourous to the pileus, slight sweetness, aromatic flavor; Stipe: cylindrical shape, surface smooth, concolourous to pileus, 1-2 mm diameter, 20-50 mm length; Basidiospores: 6-11.5 x 4-6.5 μm, ovoid-ellipsoid with smooth surface; Basidia: 65 x 10 μm, cornuted 4-6 spores per basidium. Phylogenetic analysis of nrLSU sequence yielded consistent topology in different taxa of Cantharellus. The phylogenetic position of XC02 was obtained and accepted at sub-generic level: subgenus Parvocantharellus. This clade was suggested to be monophyletic, and separated from other sub-generic levels. Morphologically phylogenetically distinct from the other species of clade 4, such as C. appalachiensis, C. tabernensis, C. aff. Congolensis. The highly supported monophyletic group with referent Cantharellus minor was obtained with the bootstrap value of 99, indicated that XC02 was significant closely to Cantharellus minor. Phylogenetic of nrLSU analysis revealed clades with statistical support corresponding to morphological observation, thus, XC2 was concluded as Cantharellus minor

KHẢ NĂNG LƯU TRỮ CACBON CỦA THẢM CỎ BIỂN TẠI ĐẦM LĂNG CÔ, TỈNH THỪA THIÊN HUẾ

Seagrass beds play an essential role in mitigating climate change by absorbing CO2 from the atmosphere and converting carbon into biomass through photosynthesis. We used remote sensing and GIS technology with field survey data to establish the distribution and above-ground dry biomass maps of seagrass beds in 2021. A Landsat 8 OLI satellite image was used in the interpretation process. An above-ground dry biomass map was established by building the regression function between the above-ground dry biomass and the reflectance spectrum of the image bands. The overall accuracy and the Kappa coefficient of the classification process were 95.5% and 0.94. At Lang Co Lagoon, the seagrass bed area in 2021 was about 36.18 ha, distributed primarily in the area between Lang Co Town and the north of the lagoon; and scattered in the north of the lagoon, Hoi Can, Hoi Dua, and Hoi Mit. In addition, the total carbon stock of seagrasses in Lang Co Lagoon was estimated at 5.54 tons, equivalent to 20.32 tons of CO2, in which the contribution of Halodule uninervis accounted for 61% of the total carbon stock.Thảm cỏ biển đóng vai trò quan trọng trong việc giảm thiểu biến đổi khí hậu thông qua việc hấp thụ CO2 từ khí quyển và chuyển cacbon thành sinh khối nhờ quá trình quang hợp. Chúng tôi đã sử dụng công nghệ viễn thám và GIS, kết hợp với dữ liệu khảo sát thực địa, để thành lập bản đồ phân bố và sinh khối khô trên mặt đất của hệ sinh thái thảm cỏ biển tại Đầm Lăng Cô vào năm 2021. Một ảnh vệ tinh Landsat 8 OLI đã được sử dụng trong quá trình giải đoán. Một bản đồ sinh khối khô trên mặt đất được thành lập thông qua việc xây dựng hàm hồi quy giữa sinh khối khô trên mặt đất và phổ phản xạ của các kênh ảnh Landsat. Độ chính xác tổng thể và hệ số Kappa là 95,5% và 0,94. Tại Đầm Lăng Cô, diện tích thảm cỏ biển năm 2021 chiếm khoảng 36,18 ha, phân bố chủ yếu ở các khu vực giao giữa Thị trấn Lăng Cô và phía Bắc của đầm; rải rác tại phía Bắc của đầm, Hói Cạn, Hói Dừa và Hói Mít. Ngoài ra, tổng trữ lượng cacbon của cỏ biển ở Đầm Lăng Cô là 5,54 tấn cacbon, tương đương với 20,32 tấn CO2; trong đó, sự đóng góp của loài Halodule uninervis chiếm 61% tổng trữ lượng cacbon

A Rare Colonic Metastasis Case from Hepatocellular Carcinoma

BACKGROUND: Hepatocellularcarcinoma (HCC) metastasis include intrahepatic and extrahepatic metastasis. Similar to intrahepatic metastasis, extrahepatic metastases are not unusual in cases with HCC. However, colonic metastasis is infrequent. CASE REPORT: We describe a clinical case, he was diagnosed with HCC a year ago, treated with TACE (transarterialchemoembolisation), re-examined with abdominal pain and defecation disorder. The tests such as CT scan, colorectal endoscopy, fine needle aspiration (FNA) revealed secondary metastatic lesion of HCC in sigmoid colon. This is the first gastrointestinal (GI) tract metastatic we have encountered. CONCLUSION: HCC metastases of the colon are rare, especially cases of hematogenous spread. The prognosis of these patients is often very critical. Indications for surgical removal of the lesion may be used if the general situation of patient is acceptable

Host Transcription Profile in Nasal Epithelium and Whole Blood of Hospitalized Children Under 2 Years of Age With Respiratory Syncytial Virus Infection.

BACKGROUND: Most insights into the cascade of immune events after acute respiratory syncytial virus (RSV) infection have been obtained from animal experiments or in vitro models. METHODS: In this study, we investigated host gene expression profiles in nasopharyngeal (NP) swabs and whole blood samples during natural RSV and rhinovirus (hRV) infection (acute versus early recovery phase) in 83 hospitalized patients <2 years old with lower respiratory tract infections. RESULTS: Respiratory syncytial virus infection induced strong and persistent innate immune responses including interferon signaling and pathways related to chemokine/cytokine signaling in both compartments. Interferon-α/β, NOTCH1 signaling pathways and potential biomarkers HIST1H4E, IL7R, ISG15 in NP samples, or BCL6, HIST2H2AC, CCNA1 in blood are leading pathways and hub genes that were associated with both RSV load and severity. The observed RSV-induced gene expression patterns did not differ significantly in NP swab and blood specimens. In contrast, hRV infection did not as strongly induce expression of innate immunity pathways, and significant differences were observed between NP swab and blood specimens. CONCLUSIONS: We conclude that RSV induced strong and persistent innate immune responses and that RSV severity may be related to development of T follicular helper cells and antiviral inflammatory sequelae derived from high activation of BCL6

Associations of Underlying Health Conditions With Anxiety and Depression Among Outpatients: Modification Effects of Suspected COVID-19 Symptoms, Health-Related and Preventive Behaviors

Objectives: We explored the association of underlying health conditions (UHC) with depression and anxiety, and examined the modification effects of suspected COVID-19 symptoms (S-COVID-19-S), health-related behaviors (HB), and preventive behaviors (PB).Methods: A cross-sectional study was conducted on 8,291 outpatients aged 18–85 years, in 18 hospitals and health centers across Vietnam from 14th February to May 31, 2020. We collected the data regarding participant's characteristics, UHC, HB, PB, depression, and anxiety.Results: People with UHC had higher odds of depression (OR = 2.11; p &lt; 0.001) and anxiety (OR = 2.86; p &lt; 0.001) than those without UHC. The odds of depression and anxiety were significantly higher for those with UHC and S-COVID-19-S (p &lt; 0.001); and were significantly lower for those had UHC and interacted with “unchanged/more” physical activity (p &lt; 0.001), or “unchanged/more” drinking (p &lt; 0.001 for only anxiety), or “unchanged/healthier” eating (p &lt; 0.001), and high PB score (p &lt; 0.001), as compared to those without UHC and without S-COVID-19-S, “never/stopped/less” physical activity, drinking, “less healthy” eating, and low PB score, respectively.Conclusion: S-COVID-19-S worsen psychological health in patients with UHC. Physical activity, drinking, healthier eating, and high PB score were protective factors

Safety and efficacy of fluoxetine on functional outcome after acute stroke (AFFINITY): a randomised, double-blind, placebo-controlled trial

Background Trials of fluoxetine for recovery after stroke report conflicting results. The Assessment oF FluoxetINe In sTroke recoverY (AFFINITY) trial aimed to show if daily oral fluoxetine for 6 months after stroke improves functional outcome in an ethnically diverse population. Methods AFFINITY was a randomised, parallel-group, double-blind, placebo-controlled trial done in 43 hospital stroke units in Australia (n=29), New Zealand (four), and Vietnam (ten). Eligible patients were adults (aged ≥18 years) with a clinical diagnosis of acute stroke in the previous 2–15 days, brain imaging consistent with ischaemic or haemorrhagic stroke, and a persisting neurological deficit that produced a modified Rankin Scale (mRS) score of 1 or more. Patients were randomly assigned 1:1 via a web-based system using a minimisation algorithm to once daily, oral fluoxetine 20 mg capsules or matching placebo for 6 months. Patients, carers, investigators, and outcome assessors were masked to the treatment allocation. The primary outcome was functional status, measured by the mRS, at 6 months. The primary analysis was an ordinal logistic regression of the mRS at 6 months, adjusted for minimisation variables. Primary and safety analyses were done according to the patient's treatment allocation. The trial is registered with the Australian New Zealand Clinical Trials Registry, ACTRN12611000774921. Findings Between Jan 11, 2013, and June 30, 2019, 1280 patients were recruited in Australia (n=532), New Zealand (n=42), and Vietnam (n=706), of whom 642 were randomly assigned to fluoxetine and 638 were randomly assigned to placebo. Mean duration of trial treatment was 167 days (SD 48·1). At 6 months, mRS data were available in 624 (97%) patients in the fluoxetine group and 632 (99%) in the placebo group. The distribution of mRS categories was similar in the fluoxetine and placebo groups (adjusted common odds ratio 0·94, 95% CI 0·76–1·15; p=0·53). Compared with patients in the placebo group, patients in the fluoxetine group had more falls (20 [3%] vs seven [1%]; p=0·018), bone fractures (19 [3%] vs six [1%]; p=0·014), and epileptic seizures (ten [2%] vs two [<1%]; p=0·038) at 6 months. Interpretation Oral fluoxetine 20 mg daily for 6 months after acute stroke did not improve functional outcome and increased the risk of falls, bone fractures, and epileptic seizures. These results do not support the use of fluoxetine to improve functional outcome after stroke

Lyapunov-Induced Model Predictive Power Control for Grid-Tie Three-Level Neutral-Point-Clamped Inverter With Dead-Time Compensation

International audienceIn this paper, a new power control strategy based on a model predictive power control for the grid-tie three-level neutral point clamped inverter is presented. A dynamical model based on the orientation of grid voltage is used to predict the performance of control variables required for the system. A cost function that includes the tracking power ability, the neutral-point voltage balancing and switching frequency reduction is used to achieve the optimal switching state. A proposed selection scheme of control input is introduced to comprehend the stability of the closed-loop system and reduce the computational cost. At each sampling time, only candidate switching state inputs that guarantee the stability condition through a control Lyapunov function is evaluated in the cost function of the MPC algorithm. Thus, the execution time is remarkably decreased by 26% in comparison with traditional model predictive control. Moreover, the dead-time effect is compensated by incorporating its influence in the proposed prediction model. Simulation and experimental results compared with the traditional model predictive control are used to confirm the effectiveness of the proposed scheme

NTCP S267F variant associates with decreased susceptibility to HBV and HDV infection and decelerated progression of related liver diseases

Objectives To determine potential associations of the rs2296651 variant (c.800C > T, S267F) of NTCP with HBV and HBV plus concomitant HDV infection as well as with the progression of related liver diseases. Methods The S267F variant was genotyped by DNA sequencing in 620 HBV-infected patients and 214 healthy controls (HCs). Among the patients, 450 individuals were tested for HDV by a nested PCR assay. Logistic regression was applied to examine the association. Results The S267F variant was found more frequently among HCs (16%) compared to HBV-infected (6%) and HBV-HDV co-infected patients (3%) (HBV patients vs HC: OR = 0.32, P = 0.00002 and HDV patients vs. HC: OR = 0.17, P = 0.018). The frequency of S267F variant was inversely correlated with CHB, LC or HCC patients compared with HCs (OR = 0.31, P = 0.001; OR = 0.32, P = 0.013; OR = 0.34, P = 0.002, respectively). S267F variant was also associated with decreased risk of the development of advanced liver cirrhosis (LC) and hepatocellular carcinoma (HCC) (Child B and C vs. Child A, OR = 0.26, adjusted P = 0.016; BCLC B,C,D vs. BCLC A, OR = 0.038, P = 0.045, respectively). In addition, patients with the genotype CT had lower levels of AST, ALT, total and direct bilirubin as well as higher platelet counts, indicating an association with a more favorable clinical outcome. Conclusion The NTCP S267F variant of the SLC10A1 gene exhibits protective effects against HBV and HDV infection and is associated with a reduced risk of developing to advanced stages of LC and HCC.Peer Reviewe