270 research outputs found
Inference algorithms for gene networks: a statistical mechanics analysis
The inference of gene regulatory networks from high throughput gene
expression data is one of the major challenges in systems biology. This paper
aims at analysing and comparing two different algorithmic approaches. The first
approach uses pairwise correlations between regulated and regulating genes; the
second one uses message-passing techniques for inferring activating and
inhibiting regulatory interactions. The performance of these two algorithms can
be analysed theoretically on well-defined test sets, using tools from the
statistical physics of disordered systems like the replica method. We find that
the second algorithm outperforms the first one since it takes into account
collective effects of multiple regulators
Detecting a stochastic gravitational wave background with the Laser Interferometer Space Antenna
The random superposition of many weak sources will produce a stochastic
background of gravitational waves that may dominate the response of the LISA
(Laser Interferometer Space Antenna) gravitational wave observatory. Unless
something can be done to distinguish between a stochastic background and
detector noise, the two will combine to form an effective noise floor for the
detector. Two methods have been proposed to solve this problem. The first is to
cross-correlate the output of two independent interferometers. The second is an
ingenious scheme for monitoring the instrument noise by operating LISA as a
Sagnac interferometer. Here we derive the optimal orbital alignment for
cross-correlating a pair of LISA detectors, and provide the first analytic
derivation of the Sagnac sensitivity curve.Comment: 9 pages, 11 figures. Significant changes to the noise estimate
Direct constraint on the distance of y2 Velorum from AMBER/VLTI observations
In this work, we present the first AMBER observations, of the Wolf-Rayet and
O (WR+O) star binary system y2 Velorum. The AMBER instrument was used with the
telescopes UT2, UT3, and UT4 on baselines ranging from 46m to 85m. It delivered
spectrally dispersed visibilities, as well as differential and closure phases,
with a resolution R = 1500 in the spectral band 1.95-2.17 micron. We interpret
these data in the context of a binary system with unresolved components,
neglecting in a first approximation the wind-wind collision zone flux
contribution. We show that the AMBER observables result primarily from the
contribution of the individual components of the WR+O binary system. We discuss
several interpretations of the residuals, and speculate on the detection of an
additional continuum component, originating from the free-free emission
associated with the wind-wind collision zone (WWCZ), and contributing at most
to the observed K-band flux at the 5% level. The expected absolute separation
and position angle at the time of observations were 5.1±0.9mas and
66±15° respectively. However, we infer a separation of
3.62+0.11-0.30 mas and a position angle of 73+9-11°. Our analysis thus
implies that the binary system lies at a distance of 368+38-13 pc, in agreement
with recent spectrophotometric estimates, but significantly larger than the
Hipparcos value of 258+41-31 pc
Calibration and Characterization of the IceCube Photomultiplier Tube
Over 5,000 PMTs are being deployed at the South Pole to compose the IceCube
neutrino observatory. Many are placed deep in the ice to detect Cherenkov light
emitted by the products of high-energy neutrino interactions, and others are
frozen into tanks on the surface to detect particles from atmospheric cosmic
ray showers. IceCube is using the 10-inch diameter R7081-02 made by Hamamatsu
Photonics. This paper describes the laboratory characterization and calibration
of these PMTs before deployment. PMTs were illuminated with pulses ranging from
single photons to saturation level. Parameterizations are given for the single
photoelectron charge spectrum and the saturation behavior. Time resolution,
late pulses and afterpulses are characterized. Because the PMTs are relatively
large, the cathode sensitivity uniformity was measured. The absolute photon
detection efficiency was calibrated using Rayleigh-scattered photons from a
nitrogen laser. Measured characteristics are discussed in the context of their
relevance to IceCube event reconstruction and simulation efforts.Comment: 40 pages, 12 figure
Search for Relativistic Magnetic Monopoles with IceCube
We present the first results in the search for relativistic magnetic
monopoles with the IceCube detector, a subsurface neutrino telescope located in
the South Polar ice cap containing a volume of 1 km. This analysis
searches data taken on the partially completed detector during 2007 when
roughly 0.2 km of ice was instrumented. The lack of candidate events
leads to an upper limit on the flux of relativistic magnetic monopoles of
\Phi_{\mathrm{90%C.L.}}\sim 3\e{-18}\fluxunits for . This is a
factor of 4 improvement over the previous best experimental flux limits up to a
Lorentz boost below . This result is then interpreted for a
wide range of mass and kinetic energy values.Comment: 11 pages, 11 figures. v2 is minor text edits, no changes to resul
Lateral Distribution of Muons in IceCube Cosmic Ray Events
In cosmic ray air showers, the muon lateral separation from the center of the
shower is a measure of the transverse momentum that the muon parent acquired in
the cosmic ray interaction. IceCube has observed cosmic ray interactions that
produce muons laterally separated by up to 400 m from the shower core, a factor
of 6 larger distance than previous measurements. These muons originate in high
pT (> 2 GeV/c) interactions from the incident cosmic ray, or high-energy
secondary interactions. The separation distribution shows a transition to a
power law at large values, indicating the presence of a hard pT component that
can be described by perturbative quantum chromodynamics. However, the rates and
the zenith angle distributions of these events are not well reproduced with the
cosmic ray models tested here, even those that include charm interactions. This
discrepancy may be explained by a larger fraction of kaons and charmed
particles than is currently incorporated in the simulations
An improved method for measuring muon energy using the truncated mean of dE/dx
The measurement of muon energy is critical for many analyses in large
Cherenkov detectors, particularly those that involve separating
extraterrestrial neutrinos from the atmospheric neutrino background. Muon
energy has traditionally been determined by measuring the specific energy loss
(dE/dx) along the muon's path and relating the dE/dx to the muon energy.
Because high-energy muons (E_mu > 1 TeV) lose energy randomly, the spread in
dE/dx values is quite large, leading to a typical energy resolution of 0.29 in
log10(E_mu) for a muon observed over a 1 km path length in the IceCube
detector. In this paper, we present an improved method that uses a truncated
mean and other techniques to determine the muon energy. The muon track is
divided into separate segments with individual dE/dx values. The elimination of
segments with the highest dE/dx results in an overall dE/dx that is more
closely correlated to the muon energy. This method results in an energy
resolution of 0.22 in log10(E_mu), which gives a 26% improvement. This
technique is applicable to any large water or ice detector and potentially to
large scintillator or liquid argon detectors.Comment: 12 pages, 16 figure
All-particle cosmic ray energy spectrum measured with 26 IceTop stations
We report on a measurement of the cosmic ray energy spectrum with the IceTop
air shower array, the surface component of the IceCube Neutrino Observatory at
the South Pole. The data used in this analysis were taken between June and
October, 2007, with 26 surface stations operational at that time, corresponding
to about one third of the final array. The fiducial area used in this analysis
was 0.122 km^2. The analysis investigated the energy spectrum from 1 to 100 PeV
measured for three different zenith angle ranges between 0{\deg} and 46{\deg}.
Because of the isotropy of cosmic rays in this energy range the spectra from
all zenith angle intervals have to agree. The cosmic-ray energy spectrum was
determined under different assumptions on the primary mass composition. Good
agreement of spectra in the three zenith angle ranges was found for the
assumption of pure proton and a simple two-component model. For zenith angles
{\theta} < 30{\deg}, where the mass dependence is smallest, the knee in the
cosmic ray energy spectrum was observed between 3.5 and 4.32 PeV, depending on
composition assumption. Spectral indices above the knee range from -3.08 to
-3.11 depending on primary mass composition assumption. Moreover, an indication
of a flattening of the spectrum above 22 PeV were observed.Comment: 38 pages, 17 figure
The IceCube Neutrino Observatory Part VI: Ice Properties, Reconstruction and Future Developments
Papers on ice properties, reconstruction and future developments submitted to
the 33nd International Cosmic Ray Conference (Rio de Janeiro 2013) by the
IceCube Collaboration.Comment: 28 pages, 38 figures; Papers submitted to the 33nd International
Cosmic Ray Conference, Rio de Janeiro 2013; version 2 corrects errors in the
author lis
- …