Marion Waltz

https://digitalcommons.library.umaine.edu/mmb-ps/2766/thumbnail.jp

Effect of Exercise in Preventing Gestational Diabetes Mellitus in Racially Diverse Overweight Pregnant Women

Title: Effect of Exercise in Preventing Gestational Diabetes Mellitus in Racially Diverse Overweight Pregnant Women Authors: Barry Francis1, Ami Eho1, Bre McDonald1, Sadaf Dabeer, Ph.D.2, Juliana Meireles, Ph.D.2, Katherine H. Ingram, Ph.D.(mentor)2 Institution: 1Department of Molecular and Cellular Biology, 2Department of Exercise Science and Sport Management, Kennesaw State University Introduction: With the increase in unhealthy lifestyles in the Western world, obesity and other chronic diseases plague our current society. Gestational diabetes mellitus (GDM) remains a major complication affecting 7-10% of pregnancies. The fetus is affected by GDM which increases chances of having diabetes in their lifetime. Racial and ethnic minority populations especially American Indians and African Americans are at a higher risk of GDM. Some studies postulated that this might be due to the prevalence of obesity in these groups. Exercise has been shown to lower the risk for GDM in overweight pregnant women. Studies reviewed the necessity of exercise pre-pregnancy and during pregnancy, but the correct amount of exercise to see these effects in racially- diverse women remains to be determined. Purpose: The aim of this study is to conduct a systematic review which evaluates the specific exercise volume required to prevent GDM in women of different races who are also overweight. Methods: PubMed, Cochrane Library, EMBASE, and the Kennesaw State University library system will be searched to identify systematic reviews and randomized trials published until 2021. Key terms to be utilized include: pregnancy, GDM, at-risk, obesity, race, and exercise/physical activity. Using these terms but omitting “obesity,” the number of sources available on PubMed narrowed to 21 sources. Of these 21 sources, based on the criteria deemed necessary for the review, different races represented, at-risk women with GDM, and the volume of exercise deemed necessary, only five of those 21 articles matched the necessary guidelines. When key terms overweight, pregnant women, exercise, GDM were entered along with the Boolean operators with terms AND, OR in PubMed, excluding the focus on diet, 78 results were obtained. With the filters of English for language and human for species checked, 10 were deemed fit. Including the five sources from the search focusing on race and the 10 sources found from an obesity focus, 15 total sources were collected. Conclusion: The findings from this study will provide more information about specific exercise volume that should be recommended as part of prenatal care to pregnant women based on their racial differences in order to decrease the prevalence of GDM in these groups

Developing a model of mental health self-care support for children and young people through an integrated evaluation of available types of provision involving systematic review, meta-analysis and case study

Background The mental health of children and young people (CYP) is a major UK public health concern. Recent policy reviews have identified that service provision for CYP with mental health needs is not as effective, responsive, accessible or child-centred as it could be. Following on from a previous National Institute for Health Research (NIHR) study into self-care support for CYP with long-term physical health needs, this study explored self-care support’s potential in CYP’s mental health. Objectives To identify and evaluate the types of mental health self-care support used by, and available to, CYP and their parents, and to establish how such support interfaces with statutory and non-statutory service provision. Design Two inter-related systematic literature reviews (an effectiveness review with meta-analysis and a perceptions review), together with a service mapping exercise and case study. Setting Global (systematic reviews); England and Wales (mapping exercise and case study). Participants (case study) Fifty-two individuals (17 CYP, 16 family members and 19 staff) were interviewed across six sites. Main outcome measures (meta-analysis) A measure of CYP’s mental health symptomatology. Data sources (literature reviews) MEDLINE, Cumulative Index to Nursing and Allied Health Literature (CINAHL), PsycINFO, All Evidence-Based Medicine (EBM) Reviews, Applied Social Sciences Index and Abstracts (ASSIA) and Education Resources Information Center (ERIC). Review methods Titles and abstracts of papers were screened for relevance then grouped into studies. Two independent reviewers extracted data from studies meeting the inclusion criteria. A descriptive analysis and meta-analysis were conducted for the effectiveness review; descriptive analyses were conducted for the perceptions review. These analyses were integrated to elicit a mixed-methods review. Results Sixty-five of 71 included studies were meta-analysable. These 65 studies elicited 71 comparisons which, when meta-analysed, suggested that self-care support interventions were effective at 6-month [standardised mean difference (SMD) = −0.20; 95% confidence interval (CI) −0.28 to −0.11] and 12-month (SMD = −0.12; 95% CI −0.17 to −0.06) follow-ups. However, judged against Cochrane criteria, the studies were mostly low quality. Key elements of self-care support identified in the perceptions review were the acquisition of knowledge and skills, peer support and the relationship with the self-care support agent; CYP also had different perceptions from adults about what is important in self-care support. The mapping exercise identified 27 providers of 33 self-care support services. According to the case study data, effective self-care support services are predicated on flexibility; straightforward access; non-judgemental, welcoming organisations and staff; the provision of time and attention; opportunities to learn and practise skills relevant to self-care; and systems of peer support. Conclusions Mental health self-care support interventions for CYP are modestly effective in the short to medium term. Self-care support can be conceptualised as a process which has overlap with ‘recovery’. CYP and their families want choice and flexibility in the provision of such interventions and a continued relationship with services after the nominal therapy period. Those delivering self-care support need to have specific child-centred attributes. Future work Future work should focus on under-represented conditions (e.g. psychosis, eating disorders, self-harm); the role of technology, leadership and readiness in self-care support; satisfaction in self-care support; the conceptualisation of self-care support in CYP’s mental health; and efficacy and cost-effectiveness

Track D Social Science, Human Rights and Political Science

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138414/1/jia218442.pd

Long-term cellular immunity of vaccines for Zaire Ebola Virus Diseases

Recent Ebola outbreaks underscore the importance of continuous prevention and disease control efforts. Authorized vaccines include Merck’s Ervebo (rVSV-ZEBOV) and Johnson & Johnson’s two-dose combination (Ad26.ZEBOV/MVA-BN-Filo). Here, in a five-year follow-up of the PREVAC randomized trial (NCT02876328), we report the results of the immunology ancillary study of the trial. The primary endpoint is to evaluate long-term memory T-cell responses induced by three vaccine regimens: Ad26–MVA, rVSV, and rVSV–booster. Polyfunctional EBOV-specific CD4+ T-cell responses increase after Ad26 priming and are further boosted by MVA, whereas minimal responses are observed in the rVSV groups, declining after one year. In-vitro expansion for eight days show sustained EBOV-specific T-cell responses for up to 60 months post-prime vaccination with both Ad26-MVA and rVSV, with no decline. Cytokine production analysis identify shared biomarkers between the Ad26-MVA and rVSV groups. In secondary endpoint, we observed an elevation of pro-inflammatory cytokines at Day 7 in the rVSV group. Finally, we establish a correlation between EBOV-specific T-cell responses and anti-EBOV IgG responses. Our findings can guide booster vaccination recommendations and help identify populations likely to benefit from revaccination

By the side of sweet Alice, or, The grave of Ben Bolt /

In bound volumes: Copyright Deposits 1820-186

Sarah Bell : song & chorus : as sung with great applause at the concerts of the Heron family /

Mode of access: Internet.From the Thomas A. Edison Collection of American Sheet Music

Ysaie le Triste, an analysis, and a study of the role of the Dwarf, Troncq

The romance is essentially an account of the lives and adventures of two knight-errants, Ysaie le Triste, and his son, Marcq l'Essilliet. In many instances, the author has been content to reproduce conventional Arthurian adventure motifs. His knights set forth on perilous quests, participate in numerous tournaments, and are occasionally permitted to enter the realm of the Fairies which lies on the fringe of their own Arthurian world. By the end of the romance, both knights have won the love of fair princesses. The author has also included in his story the biography of a hideous dwarf-character, named Troncq, who accompanies each of the knights on his quests and acts as his valet. He has permitted this strange character to play the principal role in the numerous comic episodes with which he has interspersed his narrative. The dwarf's role is, in fact, as lengthy as that of either of his masters. Nevertheless, it is only towards the end of the story that the author reveals his true identity. He is a supernatural being who has been obliged by a curse to appear on earth in a grotesque form, so that he might seek there a mortal hero capable of accomplishing various difficult tasks on his behalf. When the knight, Marcq, eventually proves himself equal to these tasks, Troncq experiences metamorphosis and regains his former beauty. The story then concludes with a description of his triumphant return to Fairyland. That the author should have permitted a hideous dwarf-valet to play such an important role in his tale of chivalry represents a drastic departure from Arthurian tradition. A survey of the dwarfs who appear in other romances reveals that they are almost invariably supernumerary characters. It is possible, however, that the author of this romance has given to the role of his dwarf a significance which is not immediately apparent to the modern reader. A study of Troncq's role reveals that his creator was a master of the difficult art of fusing together themes borrowed from very diverse sources. Troncq resembles other Arthurian dwarfs in so far as he is ugly, and plays the humble role of valet. But his true literary counterparts are not to be found in romance, but rather in certain Celtic folklore tales. Like Ysaie le Triste, these tales relate the experiences of supernatural creatures who have been obliged to appear on earth in the form of grotesque dwarfs. Unfortunately, it has not been possible to determine whether the author of the romance borrowed the theme of the ugly dwarf from the Celtic storytellers or whether they were indebted to him for it. For his description of Troncq's experiences on earth, the author has drawn upon his own observation of everyday reality; he has modelled his character after the dwarf-entertainers who are known to have frequented various medieval courts. Interestingly enough, a study of these dwarf-fools reveals that theirs was, in the eyes of their contemporaries, the most degrading function that a man could possibly exercise in society. The significance of Troncq's role is therefore quite obvious. He is a caricature of the human condition. He is a creature of supernatural origin, just as Everyman is a child of God; and the curse which has obliged him to live in exile on earth is symbolic of the mark of Original Sin which Everyman has borne since the Fall. As for his assumption of the humiliating role of entertainer, it represents the state of degradation that all men must endure while they earn their redemption. Troncq's biography and the romance of Ysaie le Triste end upon a note of optimism. The dwarf's triumphant return to the land of the Fairies is obviously intended to symbolize the happy lot awaiting all good Christians on the Day of Judgement.Arts, Faculty ofFrench, Hispanic, and Italian Studies, Department ofGraduat

Parlour waltz /

In bound volumes: Copyright Deposits 1820-186