A Social Media Give and Take: A Study of What Young Adults Would Give up to Stay Connected

Background: Social media presents both opportunities and risks for young adults. Although they may experience increased connectivity and creativity, excessive use can result in neglect of other aspects of life (e.g., physical activity, sleep). Purpose: Investigate social media usage patterns and addictions among young adults, while exploring what trade-offs they would be willing to make to stay connected on social media. Methods: Participants (N = 750) completed an online survey containing questions concerning demographics, social media usage patterns, relationships with social media, and trade-offs participants would make to remain on social media. A weighted least squares hierarchical multiple linear regression was performed to examine whether usage patterns/addiction predicted total trade-off scores. Results: Most participants (n = 727) had 2+ social media accounts, with Instagram (n = 693) being the most popular. Almost half of the sample (n = 342) reported checking social media 9+ times/day and more than three quarters spend at least one hour/day using social media (n = 626). More participants were willing to make food/drink or hobby-related trade-offs than health or life-related trade-offs. The regression was significant, F(6, 733) = 21.941, p \u3c.001, R2 = .390, with the number of social checks/day (p \u3c 0.05), time/day spent on social media (p \u3c 0.01), and social media addiction (p \u3c 0.001) all predicting increases in the number of trade-offs participants were willing to make. Conclusion: Higher social media usage rates/addiction can increase young adults\u27 willingness to make trade-offs in their personal lives to remain on social media

Student Involvement in Flipped Classroom Course Design

The purpose of this mixed-methods study was to examine changes in content knowledge, clinical reasoning, and metacognition with occupational therapy students involved in course design (collaborative participants), with participants engaged in flipped classroom model only (course participants), and to compare results between the collaborative and course participants. Forty-three occupational therapy students participated in this study. Researchers administered three pre- and post-test questionnaires and completed three focus groups. Results demonstrated both groups experienced growth in active learning and clinical reasoning and changed their perception of student involvement. The collaborative participants demonstrated additional benefits of development of relationships, increased accountability, and improved metacognitive learning

Mesocorticolimbic monoamine correlates of methamphetamine sensitization and motivation.

Methamphetamine (MA) is a highly addictive psychomotor stimulant, with life-time prevalence rates of abuse ranging from 5-10% world-wide. Yet, a paucity of research exists regarding MA addiction vulnerability/resiliency and neurobiological mediators of the transition to addiction that might occur upon repeated low-dose MA exposure, more characteristic of early drug use. As stimulant-elicited neuroplasticity within dopamine neurons innervating the nucleus accumbens (NAC) and prefrontal cortex (PFC) is theorized as central for addiction-related behavioral anomalies, we used a multi-disciplinary research approach in mice to examine the interactions between sub-toxic MA dosing, motivation for MA and mesocorticolimbic monoamines. Biochemical studies of C57BL/6J (B6) mice revealed short- (1 day), as well as longer-term (21 days), changes in extracellular dopamine, DAT and/or D2 receptors during withdrawal from 10, once daily, 2 mg/kg MA injections. Follow-up biochemical studies conducted in mice selectively bred for high vs. low MA drinking (respectively, MAHDR vs. MALDR mice), provided novel support for anomalies in mesocorticolimbic dopamine as a correlate of genetic vulnerability to high MA intake. Finally, neuropharmacological targeting of NAC dopamine in MA-treated B6 mice demonstrated a bi-directional regulation of MA-induced place-conditioning. These results extend extant literature for MA neurotoxicity by demonstrating that even subchronic exposure to relatively low MA doses are sufficient to elicit relatively long-lasting changes in mesocorticolimbic dopamine and that drug-induced or idiopathic anomalies in mesocorticolimbic dopamine may underpin vulnerability/resiliency to MA addiction

Interventions for Persons with Mild Cognitive Impairment (MCI) An Evidence-Based Practice Project

This Evidence-Based Practice (EBP) project addressed the following question: What occupational therapy and multidisciplinary/interprofessional interventions are most effective for addressing mild cognitive impairment (MCI) to improve occupational performance, functional cognition, participation, well-being, quality of life, and caregiver burden

Simulations of Supercollider Physics

The Standard Model of particle physics makes it possible to simulate complete events for physics signatures and their backgrounds in high energy collisions. Knowledge of how the produced particles interact with the materials in a detector makes it possible to simulate the response of any particular detector design to these events and so determine whether the detector could observe the signal. The combination of these techniques has played an important role in the design of new detectors, particularly those for hadron supercolliders where the high rates and small signal cross sections make the experiments very difficult. The technique is reviewed here and illustrated using the simulations of the GEM detector proposed for the Superconducting Super Collider. Although the simulations and results described here are somewhat detector-specific, we believe that they can serve as a useful model for this component of detector design for future hadron supercolliders.Comment: 99 pages, Plain TeX (macros included), includes gzipped tar file with 56/60 EPS figures for dvips. Get complete version from http://penguin.phy.bnl.gov/www/hetpapers.html or ftp://penguin.phy.bnl.gov/pub/papers/gemreview.ps.

Wildfire Risk as a Socioecological Pathology

Wildfire risk in temperate forests has become a nearly intractable problem that can be characterized as a socioecological “pathology”: that is, a set of complex and problematic interactions among social and ecological systems across multiple spatial and temporal scales. Assessments of wildfire risk could benefit from recognizing and accounting for these interactions in terms of socioecological systems, also known as coupled natural and human systems (CNHS). We characterize the primary social and ecological dimensions of the wildfire risk pathology, paying particular attention to the governance system around wildfire risk, and suggest strategies to mitigate the pathology through innovative planning approaches, analytical tools, and policies. We caution that even with a clear understanding of the problem and possible solutions, the system by which human actors govern fire-prone forests may evolve incrementally in imperfect ways and can be expected to resist change even as we learn better ways to manage CNHS

Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1

Multiple sclerosis and its preclinical model, experimental autoimmune encephalomyelitis, are marked by perivascular inflammation and demyelination. Myeloid cells, derived from circulating progenitors, are a prominent component of the inflammatory infiltrate and are believed to directly contribute to demyelination and axonal damage. How the cytotoxic activity of these myeloid cells is regulated is poorly understood. We identify CMRF-35–like molecule-1 (CLM-1) as a negative regulator of autoimmune demyelination. CLM-1 is expressed on inflammatory myeloid cells present in demyelinating areas of the spinal cord after immunization of mice with MOG35-55 (myelin oligodendrocyte glycoprotein) peptide. Absence of CLM-1 resulted in significantly increased nitric oxide and proinflammatory cytokine production, along with increased demyelination and worsened clinical scores, whereas T cell responses in the periphery or in the spinal cord remained unaffected. This study thus identifies CLM-1 as a negative regulator of myeloid effector cells in autoimmune demyelination