The materials processing research base of the Materials Processing Center

The goals and activities of the center are discussed. The center activities encompass all engineering materials including metals, ceramics, polymers, electronic materials, composites, superconductors, and thin films. Processes include crystallization, solidification, nucleation, and polymer synthesis

Automatic identification of gait events using an instrumented sock

Background: textile-based transducers are an emerging technology in which piezo-resistive properties of materials are used to measure an applied strain. By incorporating these sensors into a sock, this technology offers the potential to detect critical events during the stance phase of the gait cycle. This could prove useful in several applications, such as functional electrical stimulation (FES) systems to assist gait. Methods: we investigated the output of a knitted resistive strain sensor during walking and sought to determine the degree of similarity between the sensor output and the ankle angle in the sagittal plane. In addition, we investigated whether it would be possible to predict three key gait events, heel strike, heel lift and toe off, with a relatively straight-forward algorithm. This worked by predicting gait events to occur at fixed time offsets from specific peaks in the sensor signal. Results: our results showed that, for all subjects, the sensor output exhibited the same general characteristics as the ankle joint angle. However, there were large between-subjects differences in the degree of similarity between the two curves. Despite this variability, it was possible to accurately predict gait events using a simple algorithm. This algorithm displayed high levels of trial-to-trial repeatability. Conclusions: this study demonstrates the potential of using textile-based transducers in future devices that provide active gait assistance

Research in far ultraviolet filtering for space optical systems

Design and fabrication of multilayer interference filters for ultraviole

The influence of the cluster environment on the star formation efficiency of 12 Virgo spiral galaxies

The influence of the environment on gas surface density and star formation efficiency of cluster spiral galaxies is investigated. We extend previous work on radial profiles by a pixel-to pixel analysis looking for asymmetries due to environmental interactions. The star formation rate is derived from GALEX UV and Spitzer total infrared data. As in field galaxies, the star formation rate for most Virgo galaxies is approximately proportional to the molecular gas mass. Except for NGC 4438, the cluster environment does not affect the star formation efficiency with respect to the molecular gas. Gas truncation is not associated with major changes in the total gas surface density distribution of the inner disk of Virgo spiral galaxies. In three galaxies, possible increases in the molecular fraction and the star formation efficiency with respect to the total gas, of factors of 1.5 to 2, are observed on the windward side of the galactic disk. A significant increase of the star formation efficiency with respect to the molecular gas content on the windward side of ram pressure-stripped galaxies is not observed. The ram-pressure stripped extraplanar gas of 3 highly inclined spiral galaxies shows a depressed star formation efficiency with respect to the total gas, and one of them (NGC 4438) shows a depressed rate even with respect to the molecular gas. The interpretation is that stripped gas loses the gravitational confinement and associated pressure of the galactic disk, and the gas flow is diverging, so the gas density decreases and the star formation rate drops. However, the stripped extraplanar gas in one highly inclined galaxy (NGC 4569) shows a normal star formation efficiency with respect to the total gas. We propose this galaxy is different because it is observed long after peak pressure, and its extraplanar gas is now in a converging flow as it resettles back into the disk.Comment: 34 pages, 24 figures, accepted for publication by A&

Structure in the optical absorption edge of amorphous selenium technical note no. 8

Temperature measurement of absorption spectrum near band edge of amorphous selenium on evaporated samples with and without substrate

Remote sensing of Pacific hurricane and radiometric measurements from foam and slicks

There are no author-identified significant results in this report

Ram-pressure stripped molecular gas in the Virgo spiral galaxy NGC 4522

IRAM 30m 12CO(1-0) and 12CO(2-1) HERA observations are presented for the ram-pressure stripped Virgo spiral galaxy NGC 4522. The CO emission is detected in the galactic disk and the extraplanar gas. The extraplanar CO emission follows the morphology of the atomic gas closely but is less extended. The CO maxima do not appear to correspond to regions where there is peak massive star formation as probed by Halpha emission. The presence of molecular gas is a necessary but not sufficient condition for star formation. Compared to the disk gas, the molecular fraction of the extraplanar gas is 30% lower and the star formation efficiency of the extraplanar gas is about 3 times lower. The comparison with an existing dynamical model extended by a recipe for distinguishing between atomic and molecular gas shows that a significant part of the gas is stripped in the form of overdense arm-like structures. It is argued that the molecular fraction depends on the square root of the total large-scale density. Based on the combination of the CO/Halpha and an analytical model, the total gas density is estimated to be about 4 times lower than that of the galactic disk. Molecules and stars form within this dense gas according to the same laws as in the galactic disk, i.e. they mainly depend on the total large-scale gas density. Star formation proceeds where the local large-scale gas density is highest. Given the complex 3D morphology this does not correspond to the peaks in the surface density. In the absence of a confining gravitational potential, the stripped gas arms will most probably disperse; i.e. the density of the gas will decrease and star formation will cease.Comment: 11 pages, 15 figures, A&A accepted for publicatio

Humanin G (HNG) protects age-related macular degeneration (AMD) transmitochondrial ARPE-19 cybrids from mitochondrial and cellular damage.

Age-related macular degeneration (AMD) ranks third among the leading causes of visual impairment with a blindness prevalence rate of 8.7%. Despite several treatment regimens, such as anti-angiogenic drugs, laser therapy, and vitamin supplementation, being available for wet AMD, to date there are no FDA-approved therapies for dry AMD. Substantial evidence implicates mitochondrial damage and retinal pigment epithelium (RPE) cell death in the pathogenesis of AMD. However, the effects of AMD mitochondria and Humanin G (HNG), a more potent variant of the mitochondrial-derived peptide (MDP) Humanin, on retinal cell survival have not been elucidated. In this study, we characterized mitochondrial and cellular damage in transmitochondrial cybrid cell lines that contain identical nuclei but possess mitochondria from either AMD or age-matched normal (Older-normal (NL)) subjects. AMD cybrids showed (1) reduced levels of cell viability, lower mtDNA copy numbers, and downregulation of mitochondrial replication/transcription genes and antioxidant enzyme genes; and (2) elevated levels of genes related to apoptosis, autophagy and ER-stress along with increased mtDNA fragmentation and higher susceptibility to amyloid-β-induced toxicity compared to NL cybrids. In AMD cybrids, HNG protected the AMD mitochondria, reduced pro-apoptosis gene and protein levels, upregulated gp130 (a component of the HN receptor complex), and increased the protection against amyloid-β-induced damage. In summary, in cybrids, damaged AMD mitochondria mediate cell death that can be reversed by HNG treatment. Our results also provide evidence of Humanin playing a pivotal role in protecting cells with AMD mitochondria. In the future, it may be possible that AMD patient's blood samples containing damaged mitochondria may be useful as biomarkers for this condition. In conclusion, HNG may be a potential therapeutic target for treatment of dry AMD, a debilitating eye disease that currently has no available treatment. Further studies are needed to establish HNG as a viable mitochondria-targeting therapy for dry AMD

A dynamical model for the heavily ram pressure stripped Virgo spiral galaxy NGC 4522

A dynamical model including ram pressure stripping is applied to the strongly HI deficient Virgo spiral galaxy NGC 4522. A carefully chosen model snapshot is compared with existing VLA HI observations. The model successfully reproduces the large-scale gas distribution and the velocity field. However it fails to reproduce the large observed HI linewidths in the extraplanar component, for which we give possible explanations. In a second step, we solve the induction equation on the velocity fields of the dynamical model and calculate the large scale magnetic field. Assuming a Gaussian distribution of relativistic electrons we obtain the distribution of polarized radio continuum emission which is also compared with our VLA observations at 6 cm. The observed maximum of the polarized radio continuum emission is successfully reproduced. Our model suggests that the ram pressure maximum occurred only ~50 Myr ago. Since NGC 4522 is located far away from the cluster center (~1 Mpc) where the intracluster medium density is too low to cause the observed stripping if the intracluster medium is static and smooth, two scenarios are envisaged: (i) the galaxy moves very rapidly within the intracluster medium and is not even bound to the cluster; in this case the galaxy has just passed the region of highest intracluster medium density; (ii) the intracluster medium is not static but moving due to the infall of the M49 group of galaxies. In this case the galaxy has just passed the region of highest intracluster medium velocity. This study shows the strength of combining high resolution HI and polarized radio continuum emission with detailed numerical modeling of the evolution of the gas and the large-scale magnetic field.Comment: 15 pages, 11 figures, accepted for publication in A&