Učestalost supkliničkog endometritisa u krava koje se pregone te usporedba učinkovitosti različite antibiotske i biljne intrauterine terapije

The present research work was conducted to investigate the incidence of subclinical endometritis (SE) in repeat breeder dairy cattle, and to study the comparative efficacy of different antimicrobial and polyherbal intrauterine therapies. Repeat breeding crossbred cows (>90 days in milking) with clear cervico-vaginal mucous discharge in spontaneous estrus were examined for uterine cytology by the cytobrush technique. The cows with ≥ 4% polymorphonuclear cells (PMNs) in uterine cytology were considered to be affected with SE. These cows were randomly and equally divided (n=12/group) into 5 groups and treated with the intrauterine medicine Vodine-IU (T1), Metricare-IU (T2), Utriguard-IU (T3), Uraksha (polyherbal preparation) (T4), or left untreated (control/C). In the subsequent estrus, uterine cytology was repeated and the cows were inseminated. The cows that failed to conceive but showed estrus were re-inseminated. The pregnancy status was checked. The incidence of SE was observed to be 36.80% (60/163). The PMNs percentage significantly declined in all the treatment group cows in response to treatment. The highest conception rate was observed in the T4 group (Uraksha treated) cows. It was concluded that the uterine cytobrush technique can be used efficiently for diagnosis of SE in dairy cattle, and polyherbal intrauterine drugs may be a good alternative in intrauterine antimicrobial therapy.Rad je proveden kako bi se istražila učestalost supkliničkog endometritisa (SE) u mliječnih krava koje se pregone. Također, usporedila se učinkovitost različitih antimikrobnih i poliherbalnih intrauterinih terapijskih postupaka. U krava koje se pregone (više od 90 dana u mužnji), s čistim cerviko-vaginalnim iscjetkom iz rodnice u spontanom estrusu, tehnikom citočetkice učinjena je citološka pretraga maternice. Za krave kod kojih je utvrđeno 4% polimorfonuklearnih stanica (PMN) smatralo se da imaju supklinički endometritis. Životinje su nasumično podijeljene u pet skupina s jednakim brojem jedinki (n=12 po skupini) i liječene intrauterino sljedećim lijekovima: Vodine (skupina T1), Metricare (skupina T2), Utriguard (skupina T3), Uraksha (poliherbalni pripravak; skupina T4), dok je peta skupina bila kontrolna skupina (C). U sljedećem estrusu ponovljena je citološka analiza maternice i krave su osjemenjene. Krave nisu ostale gravidne te su u sljedećem estrusu ponovno osjemenjene. Provjeren je status gravidnosti. Incidencija SE-a bila je 36,80 % (60/163). Postotak PMN-a znatno se smanjio u svih krava u tretiranim skupinama kao odgovor na liječenje. Najveća stopa koncepcije zabilježena je u krava u skupini T4 (liječene Urakshom). Zaključeno je da tehnika citočetkica može učinkovito poslužiti u dijagnostici SE-a u mliječnih goveda te da poliherbalni intrauterini lijekovi mogu biti dobra alternativa antimikrobnoj intrauterinoj terapiji

Search for new particles in events with energetic jets and large missing transverse momentum in proton-proton collisions at root s=13 TeV

A search is presented for new particles produced at the LHC in proton-proton collisions at root s = 13 TeV, using events with energetic jets and large missing transverse momentum. The analysis is based on a data sample corresponding to an integrated luminosity of 101 fb(-1), collected in 2017-2018 with the CMS detector. Machine learning techniques are used to define separate categories for events with narrow jets from initial-state radiation and events with large-radius jets consistent with a hadronic decay of a W or Z boson. A statistical combination is made with an earlier search based on a data sample of 36 fb(-1), collected in 2016. No significant excess of events is observed with respect to the standard model background expectation determined from control samples in data. The results are interpreted in terms of limits on the branching fraction of an invisible decay of the Higgs boson, as well as constraints on simplified models of dark matter, on first-generation scalar leptoquarks decaying to quarks and neutrinos, and on models with large extra dimensions. Several of the new limits, specifically for spin-1 dark matter mediators, pseudoscalar mediators, colored mediators, and leptoquarks, are the most restrictive to date.Peer reviewe

Combined searches for the production of supersymmetric top quark partners in proton-proton collisions at root s=13 TeV

A combination of searches for top squark pair production using proton-proton collision data at a center-of-mass energy of 13 TeV at the CERN LHC, corresponding to an integrated luminosity of 137 fb(-1) collected by the CMS experiment, is presented. Signatures with at least 2 jets and large missing transverse momentum are categorized into events with 0, 1, or 2 leptons. New results for regions of parameter space where the kinematical properties of top squark pair production and top quark pair production are very similar are presented. Depending on themodel, the combined result excludes a top squarkmass up to 1325 GeV for amassless neutralino, and a neutralinomass up to 700 GeV for a top squarkmass of 1150 GeV. Top squarks with masses from 145 to 295 GeV, for neutralino masses from 0 to 100 GeV, with a mass difference between the top squark and the neutralino in a window of 30 GeV around the mass of the top quark, are excluded for the first time with CMS data. The results of theses searches are also interpreted in an alternative signal model of dark matter production via a spin-0 mediator in association with a top quark pair. Upper limits are set on the cross section for mediator particle masses of up to 420 GeV

Probing effective field theory operators in the associated production of top quarks with a Z boson in multilepton final states at root s=13 TeV

Peer reviewe

Measurement of the W gamma Production Cross Section in Proton-Proton Collisions at root s=13 TeV and Constraints on Effective Field Theory Coefficients

A fiducial cross section for W gamma production in proton-proton collisions is measured at a center-of-mass energy of 13 TeV in 137 fb(-1) of data collected using the CMS detector at the LHC. The W -> e nu and mu nu decay modes are used in a maximum-likelihood fit to the lepton-photon invariant mass distribution to extract the combined cross section. The measured cross section is compared with theoretical expectations at next-to-leading order in quantum chromodynamics. In addition, 95% confidence level intervals are reported for anomalous triple-gauge couplings within the framework of effective field theory.Peer reviewe

Search for lepton-flavor violating decays of the Higgs boson in the mu tau and e tau final states in proton-proton collisions at root s=13 TeV

A search is presented for lepton-flavor violating decays of the Higgs boson to mu t and et. The dataset corresponds to an integrated luminosity of 137 fb(-1) collected at the LHC in proton-proton collisions at a center-of-mass energy of 13 TeV. No significant excess has been found, and the results are interpreted in terms of upper limits on lepton-flavor violating branching fractions of the Higgs boson. The observed (expected) upper limits on the branching fractions are, respectively, B(H -> mu t) e tau) < 0.22(0.16)% at 95% confidence level.Peer reviewe

Observation of tW production in the single-lepton channel in pp collisions at root s=13 TeV

A measurement of the cross section of the associated production of a single top quark and a W boson in final states with a muon or electron and jets in proton-proton collisions at root s = 13 TeV is presented. The data correspond to an integrated luminosity of 36 fb(-1) collected with the CMS detector at the CERN LHC in 2016. A boosted decision tree is used to separate the tW signal from the dominant t (t) over bar background, whilst the subleading W+jets and multijet backgrounds are constrained using data-based estimates. This result is the first observation of the tW process in final states containing a muon or electron and jets, with a significance exceeding 5 standard deviations. The cross section is determined to be 89 +/- 4 (stat) +/- 12 (syst) pb, consistent with the standard model.Peer reviewe

Search for long-lived particles decaying to jets with displaced vertices in proton-proton collisions at root s=13 Te V

A search is presented for long-lived particles produced in pairs in proton-proton collisions at the LHC operating at a center-of-mass energy of 13 TeV. The data were collected with the CMS detector during the period from 2015 through 2018, and correspond to a total integrated luminosity of 140 fb(-1). This search targets pairs of long-lived particles with mean proper decay lengths between 0.1 and 100 mm, each of which decays into at least two quarks that hadronize to jets, resulting in a final state with two displaced vertices. No significant excess of events with two displaced vertices is observed. In the context of R-parity violating supersymmetry models, the pair production of long-lived neutralinos, gluinos, and top squarks is excluded at 95% confidence level for cross sections larger than 0.08 fb, masses between 800 and 3000 GeV, and mean proper decay lengths between 1 and 25 mm.Peer reviewe

Search for top squark production in fully hadronic final states in proton-proton collisions at root s=13 TeV

A search for production of the supersymmetric partners of the top quark, top squarks, is presented. The search is based on proton-proton collision events containing multiple jets, no leptons, and large transverse momentum imbalance. The data were collected with the CMS detector at the CERN LHC at a center-of-mass energy of 13 TeV, and correspond to an integrated luminosity of 137 fb(-1). The targeted signal production scenarios are direct and gluino-mediated top squark production, including scenarios in which the top squark and neutralino masses are nearly degenerate. The search utilizes novel algorithms based on deep neural networks that identify hadronically decaying top quarks and W bosons, which are expected in many of the targeted signal models. No statistically significant excess of events is observed relative to the expectation from the standard model, and limits on the top squark production cross section are obtained in the context of simplified supersymmetric models for various production and decay modes. Exclusion limits as high as 1310 GeVare established at the 95% confidence level on the mass of the top squark for direct top squark production models, and as high as 2260 GeV on the mass of the gluino for gluino-mediated top squark production models. These results represent a significant improvement over the results of previous searches for supersymmetry by CMS in the same final state.Peer reviewe