Partial Information And Partial Weight - Two New Information Theoretic Metrics To Help Specify A Data-Based Natural System Model

How to define a system? This is a problem faced routinely in science and engineering, with solutions developed from our understanding of the processes inherent, to assessing the underlying structure based on observational evidence alone. In general, system specification involves identifying a few meaningful predictors (from a large enough set that is plausibly related to the response) and formulating a relation between them and the system response being modeled. For systems where physical relationships are less apparent, and sufficient observational records exist, a range of statistical alternatives have been investigated as a possible way of specifying the underlying form. Here, we introduce partial information (PI) as a new means for specifying the system, its key advantage being the relative lack of major assumptions about the processes being modeled in order to characterize the complete system. In addition to PI which offers a means of identifying the system predictors of interest, we also introduce the concept of partial weights (PW) which use the identified predictors to formulate a predictive model that acknowledges the relative contributions varied predictor variables make to the prediction of the response. We assess the utility of the PI-PW framework using synthetically generated datasets from known linear, non-linear and high-dimensional dynamic yet chaotic systems, and demonstrate the efficacy of the procedure in ascertaining the underlying true system with varying extents of observational evidence available. We highlight how this framework can be invaluable in formulating prediction models for natural systems which are modeled using empirical or semi-empirical alternatives, and discuss current limitations that still need to be overcome

Otorhinolaryngological myiasis: the problem and its presentations in the weak and forgotten

Introduction: Myiasis is common in tropical regions, but now increasing incidence is seen in the west due to international travel. Otorhinolaryngological myiasis is uncommon and is seen in diabetics, alcoholics or patients unable in self-care.Objectives: To study presentations of otorhinolaryngological myiasis, identify associated risk factors and species of flies causing myiasis.Methods: Clinical findings and co-morbidities of 67 myiasis cases were noted. Maggots were identified, manually removed, and patients were managed with topical treatment, systemic ivermectin and antibiotics.Findings: Thirty-three nasal myiasis, 13 aural myiasis and 5 patients with oral myiasis were noted. Seven patients with head neck wounds myiasis and nine patients of tracheostome myiasis were recorded.Discussion: Warm humid climate of tropical regions is a major concern along with co-existing conditions like poor sanitation, alcoholism, psychiatric diseases and neuropathies. Hesitancy is seen in attendants and health care professionals to deal with myiasis.Conclusion: Awareness about risk factors is important in avoiding myiasis along with prompt treatment which reduces morbidity. Tracheostome myiasis is an under-documented entity rather than a rare presentation.Keywords: Myiasis, Ivermectin, screwworm, Chrysomya bezziana, Musca domestica, Lucilia sericata.Funding: Non

Quantifying GCM Simulation Uncertainty And Incorporating Into Water Resources Assessment

Rainfall and temperature, simulated using Global Climate Models (GCMs), serve as key inputs for hydrological models in studying catchment responses to climate scenarios. GCM simulations of rainfall and temperature, however, are uncertain due to model structure, scenarios and initial conditions, which results in biased outcomes if used for hydrological models without due consideration of the uncertainties. In this study, we develop a novel uncertainty metric, square root error variance (SREV), to quantify uncertainties involved in GCM rainfall and temperature simulations as well as illustrate its application for water resources assessment. The uncertainty metric involves converting multiple GCM simulations into their percentile, estimating uncertainties at each quantile and translating these uncertainties into time-series. We apply the method to estimate uncertainties in rainfall and temperature simulations using multiple GCM, scenarios and ensemble runs. The utility of the uncertainty estimate for water resources assessment is illustrated through two case studies: (1) future drought analysis across the world; and (2) water availability study at the Warragamba catchment, Sydney, Australia. In the first case, future drought is estimated using Standard Precipitation Index (SPI) with simulation-extrapolation (an algorithm that reduces parameter bias when input errors are known) being used to reduce biases in SPI parameter. In the second case, an additive error model is proposed to generate rainfall and temperature realizations that are used to simulate streamflow. Future storage requirement of the reservoir is then evaluated with its associated uncertainty using behavior analysis. The results suggest that GCM uncertainty arises mainly from model structural errors, for both rainfall and temperature. Consideration of these uncertainties in drought analysis is vital, as drought values with and without considering the uncertainties are significantly different. It is also found that the existing storage capacity of the Warragamba reservoir suffices the future requirements, although large uncertainty exists in the storage estimates

Continuous rainfall simulation: 2. A regionalized daily rainfall generation approach

This paper is the second of two in the current issue that presents a framework for simulating continuous (uninterrupted) rainfall sequences at both gaged and ungaged locations. The ultimate objective of the papers is to present a methodology for stochastically generating continuous subdaily rainfall sequences at any location such that the statistics at a range of aggregation scales are preserved. In this paper we complete the regionalized algorithm by adopting a rationale for generating daily sequences at any location by sampling daily rainfall records from "nearby" gages with statistically similar rainfall sequences.The approach consists of two distinct steps: first the identification of a set of locations with daily rainfall sequences that are statistically similar to the location of interest, and second the development of an algorithm to sample daily rainfall from those locations. In the first step, the similarity between all bivariate combinations of 2708 daily rainfall records across Australia were considered, and a logistic regression model was formulated to predict the similarity between stations as a function of a number of physiographic covariates. Based on the model results, a number of nearby locations with adequate daily rainfall records are identified for any ungaged location of interest (the "target" location), and then used as the basis for stochastically generating the daily rainfall sequences. The continuous simulation algorithm was tested at five locations where long historical daily rainfall records are available for comparison, and found to perform well in representing the distributional and dependence attributes of the observed daily record. These daily sequences were then used to disaggregate to a subdaily time step using the rainfall state-based disaggregation approach described in the first paper, and found to provide a good representation of the continuous rainfall sequences at the location of interest. Copyright 2012 by the American Geophysical Union.Rajeshwar Mehrotra, Seth Westra, Ashish Sharma and Ratnasingham Srikantha

"The fruits of independence": Satyajit Ray, Indian nationhood and the spectre of empire

Challenging the longstanding consensus that Satyajit Ray's work is largely free of ideological concerns and notable only for its humanistic richness, this article shows with reference to representations of British colonialism and Indian nationhood that Ray's films and stories are marked deeply and consistently by a distinctively Bengali variety of liberalism. Drawn from an ongoing biographical project, it commences with an overview of the nationalist milieu in which Ray grew up and emphasizes the preoccupation with colonialism and nationalism that marked his earliest unfilmed scripts. It then shows with case studies of Kanchanjangha (1962), Charulata (1964), First Class Kamra (First-Class Compartment, 1981), Pratidwandi (The Adversary, 1970), Shatranj ke Khilari (The Chess Players, 1977), Agantuk (The Stranger, 1991) and Robertsoner Ruby (Robertson's Ruby, 1992) how Ray's mature work continued to combine a strongly anti-colonial viewpoint with a shifting perspective on Indian nationhood and an unequivocal commitment to cultural cosmopolitanism. Analysing how Ray articulated his ideological positions through the quintessentially liberal device of complexly staged debates that were apparently free, but in fact closed by the scenarist/director on ideologically specific notes, this article concludes that Ray's reputation as an all-forgiving, ‘everybody-has-his-reasons’ humanist is based on simplistic or even tendentious readings of his work

An assessment of GCM skill in simulating persistence across multiple time scales

Climate change impact studies for water resource applications, such as the development of projections of reservoir yields or the assessment of likely frequency and amplitude of drought under a future climate, require that the year-to-year persistence in a range of hydrological variables such as catchment average rainfall be properly represented. This persistence is often attributable to low-frequency variability in the global sea surface temperature (SST) field and other large-scale climate variables through a complex sequence of teleconnections. To evaluate the capacity of general circulation models (GCMs) to accurately represent this low-frequency variability, a set of wavelet-based skill measures has been developed to compare GCM performance in representing interannual variability with the observed global SST data, as well as to assess the extent to which this variability is imparted in precipitation and surface pressure anomaly fields. A validation of the derived skill measures is performed using GCM precipitation as an input in a reservoir storage context, with the accuracy of reservoir storage estimates shown to be improved by using GCM outputs that correctly represent the observed low-frequency variability. Significant differences in the performance of different GCMs is demonstrated, suggesting that judicious selection of models is required if the climate impact assessment is sensitive to low-frequency variability. The two GCMs that were found to exhibit the most appropriate representation of global low-frequency variability for individual variables assessed were the Istituto Nazionale di Geofisica e Vulcanologia (INGV) ECHAM4 and L’Institut Pierre-Simon Laplace Coupled Model, version 4 (IPSL CM4); when considering all three variables, the Max Planck Institute (MPI) ECHAM5 performed well. Importantly, models that represented interannual variability well for SST also performed well for the other two variables, while models that performed poorly for SST also had consistently low skill across the remaining variables.Fiona Johnson, Seth Westra, Ashish Sharma and Andrew J. Pitma

Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: A systematic analysis from the Global Burden of Disease Study 2016

Background: A key component of achieving universal health coverage is ensuring that all populations have access to quality health care. Examining where gains have occurred or progress has faltered across and within countries is crucial to guiding decisions and strategies for future improvement. We used the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) to assess personal health-care access and quality with the Healthcare Access and Quality (HAQ) Index for 195 countries and territories, as well as subnational locations in seven countries, from 1990 to 2016. Methods Drawing from established methods and updated estimates from GBD 2016, we used 32 causes from which death should not occur in the presence of effective care to approximate personal health-care access and quality by location and over time. To better isolate potential effects of personal health-care access and quality from underlying risk factor patterns, we risk-standardised cause-specific deaths due to non-cancers by location-year, replacing the local joint exposure of environmental and behavioural risks with the global level of exposure. Supported by the expansion of cancer registry data in GBD 2016, we used mortality-to-incidence ratios for cancers instead of risk-standardised death rates to provide a stronger signal of the effects of personal health care and access on cancer survival. We transformed each cause to a scale of 0-100, with 0 as the first percentile (worst) observed between 1990 and 2016, and 100 as the 99th percentile (best); we set these thresholds at the country level, and then applied them to subnational locations. We applied a principal components analysis to construct the HAQ Index using all scaled cause values, providing an overall score of 0-100 of personal health-care access and quality by location over time. We then compared HAQ Index levels and trends by quintiles on the Socio-demographic Index (SDI), a summary measure of overall development. As derived from the broader GBD study and other data sources, we examined relationships between national HAQ Index scores and potential correlates of performance, such as total health spending per capita. Findings In 2016, HAQ Index performance spanned from a high of 97\ub71 (95% UI 95\ub78-98\ub71) in Iceland, followed by 96\ub76 (94\ub79-97\ub79) in Norway and 96\ub71 (94\ub75-97\ub73) in the Netherlands, to values as low as 18\ub76 (13\ub71-24\ub74) in the Central African Republic, 19\ub70 (14\ub73-23\ub77) in Somalia, and 23\ub74 (20\ub72-26\ub78) in Guinea-Bissau. The pace of progress achieved between 1990 and 2016 varied, with markedly faster improvements occurring between 2000 and 2016 for many countries in sub-Saharan Africa and southeast Asia, whereas several countries in Latin America and elsewhere saw progress stagnate after experiencing considerable advances in the HAQ Index between 1990 and 2000. Striking subnational disparities emerged in personal health-care access and quality, with China and India having particularly large gaps between locations with the highest and lowest scores in 2016. In China, performance ranged from 91\ub75 (89\ub71-93\ub76) in Beijing to 48\ub70 (43\ub74-53\ub72) in Tibet (a 43\ub75-point difference), while India saw a 30\ub78-point disparity, from 64\ub78 (59\ub76-68\ub78) in Goa to 34\ub70 (30\ub73-38\ub71) in Assam. Japan recorded the smallest range in subnational HAQ performance in 2016 (a 4\ub78-point difference), whereas differences between subnational locations with the highest and lowest HAQ Index values were more than two times as high for the USA and three times as high for England. State-level gaps in the HAQ Index in Mexico somewhat narrowed from 1990 to 2016 (from a 20\ub79-point to 17\ub70-point difference), whereas in Brazil, disparities slightly increased across states during this time (a 17\ub72-point to 20\ub74-point difference). Performance on the HAQ Index showed strong linkages to overall development, with high and high-middle SDI countries generally having higher scores and faster gains for non-communicable diseases. Nonetheless, countries across the development spectrum saw substantial gains in some key health service areas from 2000 to 2016, most notably vaccine-preventable diseases. Overall, national performance on the HAQ Index was positively associated with higher levels of total health spending per capita, as well as health systems inputs, but these relationships were quite heterogeneous, particularly among low-to-middle SDI countries. Interpretation GBD 2016 provides a more detailed understanding of past success and current challenges in improving personal health-care access and quality worldwide. Despite substantial gains since 2000, many low-SDI and middle- SDI countries face considerable challenges unless heightened policy action and investments focus on advancing access to and quality of health care across key health services, especially non-communicable diseases. Stagnating or minimal improvements experienced by several low-middle to high-middle SDI countries could reflect the complexities of re-orienting both primary and secondary health-care services beyond the more limited foci of the Millennium Development Goals. Alongside initiatives to strengthen public health programmes, the pursuit of universal health coverage hinges upon improving both access and quality worldwide, and thus requires adopting a more comprehensive view-and subsequent provision-of quality health care for all populations

Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: A systematic analysis from the Global Burden of Disease Study 2016

Copyright © 2018 The Author(s). Published by Elsevier Ltd. Background A key component of achieving universal health coverage is ensuring that all populations have access to quality health care. Examining where gains have occurred or progress has faltered across and within countries is crucial to guiding decisions and strategies for future improvement. We used the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) to assess personal health-care access and quality with the Healthcare Access and Quality (HAQ) Index for 195 countries and territories, as well as subnational locations in seven countries, from 1990 to 2016. Methods Drawing from established methods and updated estimates from GBD 2016, we used 32 causes from which death should not occur in the presence of effective care to approximate personal health-care access and quality by location and over time. To better isolate potential effects of personal health-care access and quality from underlying risk factor patterns, we risk-standardised cause-specific deaths due to non-cancers by location-year, replacing the local joint exposure of environmental and behavioural risks with the global level of exposure. Supported by the expansion of cancer registry data in GBD 2016, we used mortality-to-incidence ratios for cancers instead of risk-standardised death rates to provide a stronger signal of the effects of personal health care and access on cancer survival. We transformed each cause to a scale of 0-100, with 0 as the first percentile (worst) observed between 1990 and 2016, and 100 as the 99th percentile (best); we set these thresholds at the country level, and then applied them to subnational locations. We applied a principal components analysis to construct the HAQ Index using all scaled cause values, providing an overall score of 0-100 of personal health-care access and quality by location over time. We then compared HAQ Index levels and trends by quintiles on the Socio-demographic Index (SDI), a summary measure of overall development. As derived from the broader GBD study and other data sources, we examined relationships between national HAQ Index scores and potential correlates of performance, such as total health spending per capita. Findings In 2016, HAQ Index performance spanned from a high of 97·1 (95% UI 95·8-98·1) in Iceland, followed by 96·6 (94·9-97·9) in Norway and 96·1 (94·5-97·3) in the Netherlands, to values as low as 18·6 (13·1-24·4) in the Central African Republic, 19·0 (14·3-23·7) in Somalia, and 23·4 (20·2-26·8) in Guinea-Bissau. The pace of progress achieved between 1990 and 2016 varied, with markedly faster improvements occurring between 2000 and 2016 for many countries in sub-Saharan Africa and southeast Asia, whereas several countries in Latin America and elsewhere saw progress stagnate after experiencing considerable advances in the HAQ Index between 1990 and 2000. Striking subnational disparities emerged in personal health-care access and quality, with China and India having particularly large gaps between locations with the highest and lowest scores in 2016. In China, performance ranged from 91·5 (89·1-93·6) in Beijing to 48·0 (43·4-53·2) in Tibet (a 43·5-point difference), while India saw a 30·8-point disparity, from 64·8 (59·6-68·8) in Goa to 34·0 (30·3-38·1) in Assam. Japan recorded the smallest range in subnational HAQ performance in 2016 (a 4·8-point difference), whereas differences between subnational locations with the highest and lowest HAQ Index values were more than two times as high for the USA and three times as high for England. State-level gaps in the HAQ Index in Mexico somewhat narrowed from 1990 to 2016 (from a 20·9-point to 17·0-point difference), whereas in Brazil, disparities slightly increased across states during this time (a 17·2-point to 20·4-point difference). Performance on the HAQ Index showed strong linkages to overall development, with high and high-middle SDI countries generally having higher scores and faster gains for non-communicable diseases. Nonetheless, countries across the development spectrum saw substantial gains in some key health service areas from 2000 to 2016, most notably vaccine-preventable diseases. Overall, national performance on the HAQ Index was positively associated with higher levels of total health spending per capita, as well as health systems inputs, but these relationships were quite heterogeneous, particularly among low-to-middle SDI countries. Interpretation GBD 2016 provides a more detailed understanding of past success and current challenges in improving personal health-care access and quality worldwide. Despite substantial gains since 2000, many low-SDI and middle- SDI countries face considerable challenges unless heightened policy action and investments focus on advancing access to and quality of health care across key health services, especially non-communicable diseases. Stagnating or minimal improvements experienced by several low-middle to high-middle SDI countries could reflect the complexities of re-orienting both primary and secondary health-care services beyond the more limited foci of the Millennium Development Goals. Alongside initiatives to strengthen public health programmes, the pursuit of universal health coverage hinges upon improving both access and quality worldwide, and thus requires adopting a more comprehensive view - and subsequent provision - of quality health care for all populations