Basket-Handle Arch and Its Optimum Symmetry Generation as a Structural Element and Keeping the Aesthetic Point of View

The arches were a great advance in construction with respect to the rigid Greek linteled architecture. Its development came from the hand of the great Roman constructions, especially with the semicircular arch. In successive historical periods, different types of arches have been emerging, which in addition to their structural function was taking aesthetic characteristics that are used today to define the architectural style. When, in the construction of a bow, the rise is less than half the springing line, the semicircular arch is no longer used and the segmental arch is used, and then on to another more efficient and aesthetic arch, the basket-handle arch. This study examines the classic geometry of the basket-handle arch also called the three-centered arch. A solution is proposed from a constructive and aesthetic point of view, and this is approached both geometrically and analytically, where the relationship between the radius of the central arch and the radius of the lateral arch is minimized. The solution achieved allows the maximum springing line or clear span to be saved with the minimum rise that preserves the aesthetic point of view, since the horizontal thrust of a bow is greater than the relationship between the springing line of the arch and the rise. This solution has been programmed and the resulting software has made it possible to analyse existing arches in historic buildings or constructions to check if their solutions were close or not from both points of view. Thus, it has been possible to verify that in most of the existing arches analyzed, the proposed solution is reached

J’ai de sérieuses raisons de croire… à la phraséodidactique plurilingue

This article focuses on the analysis of phraseological units in Le Petit Prince by Antoine de Saint-Exupéry, drawing upon the linguistic approach of Explanatory and Combinatorial Lexicology (LEC). The starting point is the concept of phraseological unit, which is described in the selected corpus along two axes, namely, a lexico-semantic axis and a textual one. The present article shows that phrasemes play a fundamental role for the comprehension of the text (in this case in French and Spanish) and provide textual cohesion from inferences during the elaboration of meaning.This article focuses on the analysis of phraseological units in Le Petit Prince by Antoine de Saint-Exupéry, drawing upon the linguistic approach of Explanatory and Combinatorial Lexicology (LEC). The starting point is the concept of phraseological unit, which is described in the selected corpus along two axes, namely, a lexico-semantic axis and a textual one. The present article shows that phrasemes play a fundamental role for the comprehension of the text (in this case in French and Spanish) and provide textual cohesion from inferences during the elaboration of meaning.Dans ce travail, nous nous intéressons à l’analyse des unités phraséologiques dans l’oeuvre de Saint-Exupéry, Le Petit Prince, en nous inspirant de la Lexicologie Explicative et Combinatoire (LEC). Le point de départ est le concept d’unité phraséologique, qui est décrit dans le corpus sélectionné le long de deux axes, à savoir, un axe lexico-sémantique et un axe textuel. L’article montre que les phrasèmes jouent un rôle fondamental dans la compréhension du texte (en l’occurrence en français et en espagnol) et fournissent une cohésion textuelle à partir d’inférences lors de l’élaboration du sens

Basket-Handle Arch and Its Optimum Symmetry Generation as a Structural Element and Keeping the Aesthetic Point of View

The arches were a great advance in construction with respect to the rigid Greek linteled architecture. Its development came from the hand of the great Roman constructions, especially with the semicircular arch. In successive historical periods, different types of arches have been emerging, which in addition to their structural function was taking aesthetic characteristics that are used today to define the architectural style. When, in the construction of a bow, the rise is less than half the springing line, the semicircular arch is no longer used and the segmental arch is used, and then on to another more efficient and aesthetic arch, the basket-handle arch. This study examines the classic geometry of the basket-handle arch also called the three-centered arch. A solution is proposed from a constructive and aesthetic point of view, and this is approached both geometrically and analytically, where the relationship between the radius of the central arch and the radius of the lateral arch is minimized. The solution achieved allows the maximum springing line or clear span to be saved with the minimum rise that preserves the aesthetic point of view, since the horizontal thrust of a bow is greater than the relationship between the springing line of the arch and the rise. This solution has been programmed and the resulting software has made it possible to analyse existing arches in historic buildings or constructions to check if their solutions were close or not from both points of view. Thus, it has been possible to verify that in most of the existing arches analyzed, the proposed solution is reached

Eurom.com.text: etiquetado semántico

Dans ce travail nous présentons l’étiquetage sémantique du projet d’enseignement plurilingue de langues romanes Eurom.com.text. Nous analysons un corpus en quatre langues (le catalan, le français, l’italien et le portugais) avec une typologie textuelle en fonction du type et genre textuels. Ce projet a comme objectif principal la compréhension de ces quatre langues par un locuteur adulte hispanophon

Integración de Datos Psicológicos y Sociales en la Historia Clínica Electrónica de Personas con VIH/SIDA

Este artículo realiza un análisis de la situación actual de la enfermedad del SIDA, destacando la necesaria incorporación de aspectos psicológicos y sociales en el tratamiento de las personas infectadas con el objetivo de aumentar su calidad de vida. Esta incorporación nos llevaría a un tratamiento integral de los pacientes mediante el uso de una Historia Clínica Electrónica que incluyese tanto los datos médicos como aquellos que hacen referencia al estado psicológico y social de los mismos. Este análisis ha dado lugar al diseño y desarrollo de un sistema de telemedicina, "Hospital VIHrtual", que entre otras funciones realiza esa integración de datos, fomentando la colaboración entre los profesionales implicados en el tratamiento de los pacientes con el objetivo de mejorar el control de las personas con VIH/SIDA en estado estable y aumentar su calidad de vida

Fundamento y diseño de un proyecto de evaluación de la integración educativa de los niños con necesidades especiales por su deficiencia visual

Este artículo pretende dar a conocer una investigación de evaluación de la educación integrada con niños ciegos y deficientes visuales en España que se está realizando por la O.N.C.E. con un grupo de profesores de la Universidad Autónoma de Madrid. En él se hace un resumen de los objetivos y naturaleza de la investigación evaluativa emprendida, valorativa, iluminativa y formativa, y un análisis del diseño, variables y metodología usada en la investigaciónThis article feports a research work on the evaluation of educational integration with blind and visually handicapped children in Spain. The research is being conducted by the O.N.C.E. in collaboration with a group o teachers of the Universidad Autónoma de Madrid. It outlines the objectives and nature of the evaluative study undertaken (valuative, instructive and formative) and analyzes the design, thé variables and the methodology used in the stud

LPS promotes Th2 dependent sensitisation leading to anaphylaxis in a Pru p 3 mouse model

Pru p 3 is the major peach allergen in the Mediterranean area. It frequently elicits severe reactions, limiting its study in humans, raising the need for animal models to investigate the immunological mechanisms involved. However, no anaphylaxis model exists for Pru p 3. We aimed to develop a model of peach anaphylaxis by sensitising mice with Pru p 3 in combination with lipopolysaccharide (LPS) as an adjuvant. Four groups of mice were sensitised intranasally: untreated; treated with Pru p 3; treated with LPS; treated with Pru p 3 + LPS. After sensitisation mice were intraperitoneally challenged with Pru p 3 and in vivo and in vitro parameters were evaluated. Only mice in the Pru p 3 + LPS group showed anaphylaxis symptoms, including a decrease in temperature. Determination of in vitro parameters showed a Th2 response with an increase of Pru p 3-specific IgE and IgG1. Moreover, at the cellular level, we found increased levels of IgE and IgG1 secreting Pru p 3-specific cells and a proliferative CD4+ T-cell response. These results demonstrate that Pru p 3-specific anaphylaxis can be generated after nasal sensitisation to Pru p 3 in combination with LPS. This is a promising model for evaluating food allergy immunotherapies.Unión Europea, Ministerio de Economía y Competitividad, Instituto de Salud "Carlos III" PI12 / 02481Unión Europea, Ministerio de Economía y Competitividad, Instituto de Salud "Carlos III" PI15 / 00559Unión Europea, Ministerio de Economía y Competitividad, Instituto de Salud "Carlos III" RD 07/0064Unión Europea, Ministerio de Economía y Competitividad, Instituto de Salud "Carlos III" RD12 / 0013/0001Unión Europea, Ministerio de Economía y Competitividad, Instituto de Salud "Carlos III" RD07 / 0064/0003Unión Europea, Ministerio de Economía y Competitividad, Instituto de Salud "Carlos III" RD12 / 0013/0016Unión Europea, Ministerio de Andalucía Economía y Conocimiento CTS-7433Unión Europea, Ministerio de Andalucía Economía y Conocimiento C-0044-2012 SAS2013Unión Europea, Ministerio de Andalucía Economía y Conocimiento Ref. CD14 / 00242Unión Europea, Ministerio de Andalucía Economía y Conocimiento BIO2013- 41403-

Nuraghe project: Strategies for the creation of a digital environment for international coexistence

[EN] The Nuraghe Project is an international archaeological research and training project in the southwest of Sardinia: the Nuraghe Candelargiu, in San Giovanni Suergiu(SU). As the work progressed, the need to create a common window in which to further develop the project and make the site accessible was highlighted, especially after the COVID pandemic that prevented the archaeology workshop from being held for the last two years, in order to allow a continuous transfer of knowledge based on the activities that characterize it: training, research, cultural exchange and coexistence. From this need was born "Virtual Candelargiu" as an interactive space integrated within the Nuraghe Project website and with the aim of becoming a place of learning and coexistence where the values that distinguish the project are combined, being its fundamental pillar the protection of archaeological heritage from collaborative work.[ES] El Proyecto Nuraghe es un proyecto internacional de investigación y formación arqueológica de uno de los yacimientos más importantes del suroeste de Cerdeña: el Nuraghe Candelargiu, en San Giovanni Suergiu (SU). Con el avance de los trabajos se puso de relieve la necesidad de crear una ventana común en la que poder seguir desarrollando el proyecto y hacer accesible el yacimiento, especialmente tras la pandemia del COVID que impidió la realización del curso de arqueología los dos últimos años, para así permitir una continua transferencia del conocimiento a partir de las actividades que lo caracterizan: la formación, la investigación, el intercambio cultural y la convivencia. De dicha necesidad nace “Candelargiu Virtual” como espacio interactivo integrado dentro de la web del Proyecto Nuraghe y con el objetivo de convertirse en un lugar de aprendizaje y convivencia donde se aúnen los valores que singularizan al proyecto, siendo su pilar fundamental la protección del patrimonio arqueológico a partir del trabajo colaborativo. Rodríguez Azogue, A.; Carranza Peco, LM.; Gómez Díaz, A.; Puddu, M.; Rodríguez Gutiérrez, O.; Fernández Flores, Á. (2022). Proyecto Nuraghe: Estrategias para la creación de un entorno digital de convivencia internacional. En CIMED22 - II Congreso internacional de museos y estrategias digitales. Editorial Universitat Politècnica de València. 353-368. https://doi.org/10.4995/CIMED22.2022.1558535336

Expressed sequence tags (ESTs) from immune tissues of turbot (Scophthalmus maximus) challenged with pathogens

Background: The turbot (Scophthalmus maximus; Scophthalmidae; Pleuronectiformes) is a flatfish species of great relevance for marine aquaculture in Europe. In contrast to other cultured flatfish, very few genomic resources are available in this species. Aeromonas salmonicida and Philasterides dicentrarchi are two pathogens that affect turbot culture causing serious economic losses to the turbot industry. Little is known about the molecular mechanisms for disease resistance and hostpathogen interactions in this species. In this work, thousands of ESTs for functional genomic studies and potential markers linked to ESTs for mapping (microsatellites and single nucleotide polymorphisms (SNPs)) are provided. This information enabled us to obtain a preliminary view of regulated genes in response to these pathogens and it constitutes the basis for subsequent and more accurate microarray analysis. Results: A total of 12584 cDNAs partially sequenced from three different cDNA libraries of turbot (Scophthalmus maximus) infected with Aeromonas salmonicida, Philasterides dicentrarchi and from healthy fish were analyzed. Three immune-relevant tissues (liver, spleen and head kidney) were sampled at several time points in the infection process for library construction. The sequences were processed into 9256 high-quality sequences, which constituted the source for the turbot EST database. Clustering and assembly of these sequences, revealed 3482 different putative transcripts, 1073 contigs and 2409 singletons. BLAST searches with public databases detected significant similarity (e-value ≤ 1e-5) in 1766 (50.7%) sequences and 816 of them (23.4%) could be functionally annotated. Two hundred three of these genes (24.9%), encoding for defence/immunerelated proteins, were mostly identified for the first time in turbot. Some ESTs showed significant differences in the number of transcripts when comparing the three libraries, suggesting regulation in response to these pathogens. A total of 191 microsatellites, with 104 having sufficient flanking sequences for primer design, and 1158 putative SNPs were identified from these EST resources in turbot. Conclusion: A collection of 9256 high-quality ESTs was generated representing 3482 unique turbot sequences. A large proportion of defence/immune-related genes were identified, many of them regulated in response to specific pathogens. Putative microsatellites and SNPs were identified. These genome resources constitute the basis to develop a microarray for functional genomics studies and marker validation for genetic linkage and QTL analysis in turbot.This study was supported by a Consellería de Pesca e Asuntos Marítimos and the Dirección Xeral de I+D – Xunta de Galicia project (2004/CP480)S