Evaluating the use of robots to enlarge AAL services

We introduce robots as a tools to enhance Ambient Assisted Living (AAL) services. Robots are a unique opportunity to create new systems to cooperate in reaching better living conditions. Robots offer the possibility of richer interaction with humans, and can perform actions to actively change the environment. The current state-of-art includes skills in various areas, including advanced interaction (natural language, visual attention, object recognition, intention learning), navigation (map learning, obstacle avoidance), manipulation (grasping, use of tools), and cognitive architectures to handle highly unpredictable environments. From our experience in several robotics projects and principally in the RoboCup@Home competition, a new set of evaluation methods is proposed to assess the maturity of the required skills. Such comparison should ideally enable the abstraction from the particular robotic platform and concentrate on the easy comparison of skills. The validity of that low-level skills can be then scaled to more complex tasks, that are composed by several skills. Our conclusion is that effective evaluation methods can be designed with the objective of enabling robots to enlarge AAL services.This research was partly supported by the PATRICIA project (TIN2012-38416-C03-01), MANIPlus project (201350E102), Spanish Ministry of Economy and Competitiveness, and European Found for Regional Development (FEDER).Peer Reviewe

Guest editorial: sensorimotor contingencies for cognitive robotics

© 20xx IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.The sensorimotor approach to cognition states, that the key to bring semantics to the world of a robot, requires making the robot learn the relation between the actions that the robot performs and the change it experiences in its sensed data because of those actions. Those relations are called sensorimotor contingencies (SMCs). This special issue presents a variety of recent developments in SMCs with a particular focus on cognitive robotics applications.Peer ReviewedPostprint (author's final draft

Guest editorial: sensorimotor contingencies for cognitive robotics

© 20xx IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.The sensorimotor approach to cognition states, that the key to bring semantics to the world of a robot, requires making the robot learn the relation between the actions that the robot performs and the change it experiences in its sensed data because of those actions. Those relations are called sensorimotor contingencies (SMCs). This special issue presents a variety of recent developments in SMCs with a particular focus on cognitive robotics applications.Peer ReviewedPostprint (author's final draft

Cytomegalovirus protein m154 perturbs the adaptor protein-1 compartment mediating broad-spectrum immune evasion

Cytomegaloviruses (CMVs) are ubiquitous pathogens known to employ numerous immunoevasive strategies that significantly impair the ability of the immune system to eliminate the infected cells. Here, we report that the single mouse CMV (MCMV) protein, m154, downregulates multiple surface molecules involved in the activation and costimulation of the immune cells. We demonstrate that m154 uses its cytoplasmic tail motif, DD, to interfere with the adaptor protein-1 (AP-1) complex, implicated in intracellular protein sorting and packaging. As a consequence of the perturbed AP-1 sorting, m154 promotes lysosomal degradation of several proteins involved in T cell costimulation, thus impairing virus-specific CD8+ T cell response and virus control in vivo. Additionally, we show that HCMV infection similarly interferes with the AP-1 complex. Altogether, we identify the robust mechanism employed by single viral immunomodulatory protein targeting a broad spectrum of cell surface molecules involved in the antiviral immune response

Risk factors associated with non-alcoholic fatty liver disease in subjects from primary care units. A case-control study

<p>Abstract</p> <p>Background</p> <p>Non alcoholic fatty liver disease (NAFL) consists in the accumulation of fat vacuoles in the cytoplasm of hepatocytes. Many etiologic factors are associated with NAFL, such as, the metabolic syndrome factors, medications, bariatric surgery, nutritional disorders. However, very little information is available on the clinical relevance of this disorder as a health problem in the general population.</p> <p>Methods and design</p> <p>The aim of the study is establish the risk factors most frequently associated with NAFL in a general adult population assigned to the primary care units and to investigate the relationship between each component of the metabolic syndrome and the risk of having a NAFL.</p> <p>A population based case-control, observational and multicenter study will be carried out in 18 primary care units from the "Area de Gestión del Barcelonés Nord y Maresme" (Barcelona) attending a population of 360,000 inhabitants and will include 326 cases and 370 controls. Cases are defined as all subjects fulfilling the inclusion criteria and with evidence of fatty liver in an abdominal ultrasonography performed for any reason. One control will be randomly selected for each case from the population, matched for age, gender and primary care center. Controls with fatty liver or other liver diseases will be excluded.</p> <p>All cases and controls will be asked about previous hepatic diseases, consumption of alcohol, smoking and drugs, and a physical examination, biochemical analyses including liver function tests, the different components of the metabolic syndrome and the HAIR score will also be performed. Paired controls will also undergo an abdominal ultrasonography.</p> <p>Discussion</p> <p>This study will attempt to determine the factors most frequently associated with the presence of NAFL investigate the relationship between the metabolic syndrome and the risk of fatty liver and study the influence of the different primary care professionals in avoiding the evolution of the disease.</p

Prevalence and factors associated with the presence of non alcoholic fatty liver disease in an apparently healthy adult population in primary care units

<p>Abstract</p> <p>Background</p> <p>Fatty liver disease is characterized by the accumulation of fat vacuoles inside of the hepatocytes. Non alcoholic fatty liver is associated with obesity, type 2 diabetes, dyslipemia, the intake of certain drugs and with the so-called metabolic syndrome. However, there is little information on the clinical relevance of this disorder as a healthcare problem in the general population, since the studies published generally include a limited number of patients and the diagnosis is established on the basis of clear biochemical alterations and liver biopsy.</p> <p>Methods/Design</p> <p>The aim of the study is the prevalence of non-alcoholic fatty liver disease in a general adult population by hepatic ultrasonography.</p> <p>A population-based, descriptive, transversal, multicentre study. Eighteen primary care centres of the north of Barcelona and the Maresme Areas of Healthcare Management attending an urban and semi-urban population of 360.000 inhabitants.</p> <p>A randomized sample of 786 subjects of 15 years or older were selected from the population and assigned to the participating centres according to the Primary Care Information System (SIAP): This population is practically the same as the general population of the area.</p> <p>The following determinations will be carried out in all the participants: hepatic ultrasonography to detect fatty liver, a questionnaire concerning liver diseases, alcohol intake, smoking and drug use, physical examination including abdominal perimeter and body mass index and biochemical analysis including liver function tests and parameters related to the metabolic syndrome and the HAIR score.</p> <p>Ultrasonographic diagnosis of fatty liver will be made according to established criteria (American Gastroenterology Association) and diagnosis of metabolic syndrome according to the criteria of the European Group for the Study of Insulin Resistance.</p> <p>Discussion</p> <p>This study will attempt to determine the prevalence of non alcoholic fatty liver disease, as well as, the factors most frequently associated with the presence of this disease to thereby achieve the most appropriate treatment and avoid the evolution of the disease.</p

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

Guest editorial sensorimotor contingencies for cognitive robotics

The sensorimotor approach to cognition states, that the key to bring semantics to the world of a robot, requires making the robot learn the relation between the actions that the robot performs and the change it experiences in its sensed data because of those actions. Those relations are called sensorimotor contingencies (SMCs). This special issue presents a variety of recent developments in SMCs with a particular focus on cognitive robotics applications.Peer Reviewe

Inspection of social care services for older people London Borough of Ealing 4-18 July 2000

SIGLEAvailable from British Library Document Supply Centre-DSC:m00/44061 / BLDSC - British Library Document Supply CentreGBUnited Kingdo

Evaluating the use of robots to enlarge AAL services

We introduce robots as a tools to enhance Ambient Assisted Living (AAL) services. Robots are a unique opportunity to create new systems to cooperate in reaching better living conditions. Robots offer the possibility of richer interaction with humans, and can perform actions to actively change the environment. The current state-of-art includes skills in various areas, including advanced interaction (natural language, visual attention, object recognition, intention learning), navigation (map learning, obstacle avoidance), manipulation (grasping, use of tools), and cognitive architectures to handle highly unpredictable environments. From our experience in several robotics projects and principally in the RoboCup@Home competition, a new set of evaluation methods is proposed to assess the maturity of the required skills. Such comparison should ideally enable the abstraction from the particular robotic platform and concentrate on the easy comparison of skills. The validity of that low-level skills can be then scaled to more complex tasks, that are composed by several skills. Our conclusion is that effective evaluation methods can be designed with the objective of enabling robots to enlarge AAL services