35 research outputs found

    O PACIENTE NO SISTEMA CENTRO CIRÚRGICO - UM ESTUDO SOBRE PERCEPÇÕES E OPINIÕES DE PACIENTES EM RELAÇÃO AO PERIODO TRANSOPERATÓRIO

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    The author made a study about the perceptions and opinions of the patient, during the period of transoperatory, in relation with the fisical human surroudings of the surgical system in three hospitals in Londrina.A autora fez um estudo sobre as percepçÔes e opiniĂ”es do paciente, durante o periodo transoperatĂłrio, relacionadas ao ambiente fĂ­sico e humano do sistema centro cirĂșrgico em trĂȘs hospitais de Londrina

    Turismo y Género. Una mirada desde Iberoamérica

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    En las Ășltimas cuatro dĂ©cadas ha crecido el interĂ©s de la academia, gobiernos y organizaciones internacionales por estudiar cĂłmo ha sido, en quĂ© circunstancias y quĂ© efectos ha traĂ­do la incorporaciĂłn de las mujeres al turismo. De esta forma se inicia un debate internacional en el que se cuestionan, por un lado, los efectos negativos de esta actividad en la vida de las mujeres y, por el otro, se realzan beneficios econĂłmicos que mejoran su calidad de vida y la de sus familias. A pesar del interĂ©s y la importante participaciĂłn de mujeres en el sector turĂ­stico, aĂșn son insuficientes los estudios enfocados en explicar y evidenciar su situaciĂłn laboral. En este contexto, surge la idea de publicar un libro que compilara trabajos recientes en torno a las condiciones de las trabajadoras en el sector turĂ­stico de IberoamĂ©rica.Esta obra se compone de tres secciones, Aproximaciones teĂłrico metodolĂłgicas, Mujer y turismo en zonas rurales y La mujer en empresas turĂ­sticas, cuyas investigaciones abordan distintos temas para evidenciar los problemas enfrentados por las mujeres, proponer diversas soluciones y comprender su escenario laboral. En la primera secciĂłn, hay dos capĂ­tulos que proponen marcos teĂłricos para analizar el empoderamiento de las mujeres en el turismo rural. Los resultados de investigaciones de la segunda secciĂłn visibilizan las desigualdades, reflexionan y proponen acciones para mejorar las condiciones de las trabajadoras turĂ­sticas. En la Ășltima, en los tres capĂ­tulos, concentrados en las actividades empresariales, se estudian las desventajas y obstĂĄculos de la empleada en alguna compañía turĂ­stica.Universidad AutĂłnoma del Estado de MĂ©xico

    Diretrizes para Cessação do Tabagismo

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    Universidade Federal do Rio de Janeiro Hospital UniversitĂĄrio Clementino Fraga FilhoUniversidade Federal de Pelotas Faculdade de MedicinaUniversidade Federal da Bahia Faculdade de MedicinaUniversidade Federal de Pernambuco Faculdade de MedicinaUniversidade de BrasĂ­lia Faculdade de MedicinaSecretaria de Estado de SaĂșde Coordenador do Controle do TabagismoUniversidade Federal de SĂŁo Paulo (UNIFESP) Faculdade de MedicinaUniversidade Federal do Rio de Janeiro Faculdade de MedicinaUniversidade Federal do Mato Grosso Faculdade de CiĂȘncias MĂ©dicasMinistĂ©rio da SaĂșde Instituto Nacional do CĂąncerPontifĂ­cia Universidade CatĂłlica Hospital UniversitĂĄrio Faculdade de MedicinaUNESP Faculdade de Medicina de BotucatuSecretaria de Estado de SaĂșde do ParanĂĄ Programa Estadual de Controle de TabagismoUniversidade CatĂłlica do Rio Grande do Sul Faculdade de MedicinaUNIVAG Faculdade de OdontologiaUniversidade Federal de Minas Gerais Faculdade de MedicinaUniversidade Federal do Rio Grande Faculdade de MedicinaHospital de Messejana AmbulatĂłrio de Apoio ao TabagistaHospital do Servidor PĂșblico Estadual de SĂŁo PauloUniversidade Federal do Mato Grosso do SulUNIFESP, Faculdade de MedicinaSciEL

    Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

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    Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have generated broad interest, as evidenced by the steady year-on-year increase in the numbers of scientific publications about EVs. Important advances have been made in EV metrology and in understanding and applying EV biology. However, hurdles remain to realising the potential of EVs in domains ranging from basic biology to clinical applications due to challenges in EV nomenclature, separation from non-vesicular extracellular particles, characterisation and functional studies. To address the challenges and opportunities in this rapidly evolving field, the International Society for Extracellular Vesicles (ISEV) updates its 'Minimal Information for Studies of Extracellular Vesicles', which was first published in 2014 and then in 2018 as MISEV2014 and MISEV2018, respectively. The goal of the current document, MISEV2023, is to provide researchers with an updated snapshot of available approaches and their advantages and limitations for production, separation and characterisation of EVs from multiple sources, including cell culture, body fluids and solid tissues. In addition to presenting the latest state of the art in basic principles of EV research, this document also covers advanced techniques and approaches that are currently expanding the boundaries of the field. MISEV2023 also includes new sections on EV release and uptake and a brief discussion of in vivo approaches to study EVs. Compiling feedback from ISEV expert task forces and more than 1000 researchers, this document conveys the current state of EV research to facilitate robust scientific discoveries and move the field forward even more rapidly

    Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021

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    Background: Future trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and prioritisation. We have expanded and improved upon previous forecasts produced as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) and provide a reference forecast (the most likely future), and alternative scenarios assessing disease burden trajectories if selected sets of risk factors were eliminated from current levels by 2050. Methods: Using forecasts of major drivers of health such as the Socio-demographic Index (SDI; a composite measure of lag-distributed income per capita, mean years of education, and total fertility under 25 years of age) and the full set of risk factor exposures captured by GBD, we provide cause-specific forecasts of mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) by age and sex from 2022 to 2050 for 204 countries and territories, 21 GBD regions, seven super-regions, and the world. All analyses were done at the cause-specific level so that only risk factors deemed causal by the GBD comparative risk assessment influenced future trajectories of mortality for each disease. Cause-specific mortality was modelled using mixed-effects models with SDI and time as the main covariates, and the combined impact of causal risk factors as an offset in the model. At the all-cause mortality level, we captured unexplained variation by modelling residuals with an autoregressive integrated moving average model with drift attenuation. These all-cause forecasts constrained the cause-specific forecasts at successively deeper levels of the GBD cause hierarchy using cascading mortality models, thus ensuring a robust estimate of cause-specific mortality. For non-fatal measures (eg, low back pain), incidence and prevalence were forecasted from mixed-effects models with SDI as the main covariate, and YLDs were computed from the resulting prevalence forecasts and average disability weights from GBD. Alternative future scenarios were constructed by replacing appropriate reference trajectories for risk factors with hypothetical trajectories of gradual elimination of risk factor exposure from current levels to 2050. The scenarios were constructed from various sets of risk factors: environmental risks (Safer Environment scenario), risks associated with communicable, maternal, neonatal, and nutritional diseases (CMNNs; Improved Childhood Nutrition and Vaccination scenario), risks associated with major non-communicable diseases (NCDs; Improved Behavioural and Metabolic Risks scenario), and the combined effects of these three scenarios. Using the Shared Socioeconomic Pathways climate scenarios SSP2-4.5 as reference and SSP1-1.9 as an optimistic alternative in the Safer Environment scenario, we accounted for climate change impact on health by using the most recent Intergovernmental Panel on Climate Change temperature forecasts and published trajectories of ambient air pollution for the same two scenarios. Life expectancy and healthy life expectancy were computed using standard methods. The forecasting framework includes computing the age-sex-specific future population for each location and separately for each scenario. 95% uncertainty intervals (UIs) for each individual future estimate were derived from the 2·5th and 97·5th percentiles of distributions generated from propagating 500 draws through the multistage computational pipeline. Findings: In the reference scenario forecast, global and super-regional life expectancy increased from 2022 to 2050, but improvement was at a slower pace than in the three decades preceding the COVID-19 pandemic (beginning in 2020). Gains in future life expectancy were forecasted to be greatest in super-regions with comparatively low life expectancies (such as sub-Saharan Africa) compared with super-regions with higher life expectancies (such as the high-income super-region), leading to a trend towards convergence in life expectancy across locations between now and 2050. At the super-region level, forecasted healthy life expectancy patterns were similar to those of life expectancies. Forecasts for the reference scenario found that health will improve in the coming decades, with all-cause age-standardised DALY rates decreasing in every GBD super-region. The total DALY burden measured in counts, however, will increase in every super-region, largely a function of population ageing and growth. We also forecasted that both DALY counts and age-standardised DALY rates will continue to shift from CMNNs to NCDs, with the most pronounced shifts occurring in sub-Saharan Africa (60·1% [95% UI 56·8–63·1] of DALYs were from CMNNs in 2022 compared with 35·8% [31·0–45·0] in 2050) and south Asia (31·7% [29·2–34·1] to 15·5% [13·7–17·5]). This shift is reflected in the leading global causes of DALYs, with the top four causes in 2050 being ischaemic heart disease, stroke, diabetes, and chronic obstructive pulmonary disease, compared with 2022, with ischaemic heart disease, neonatal disorders, stroke, and lower respiratory infections at the top. The global proportion of DALYs due to YLDs likewise increased from 33·8% (27·4–40·3) to 41·1% (33·9–48·1) from 2022 to 2050, demonstrating an important shift in overall disease burden towards morbidity and away from premature death. The largest shift of this kind was forecasted for sub-Saharan Africa, from 20·1% (15·6–25·3) of DALYs due to YLDs in 2022 to 35·6% (26·5–43·0) in 2050. In the assessment of alternative future scenarios, the combined effects of the scenarios (Safer Environment, Improved Childhood Nutrition and Vaccination, and Improved Behavioural and Metabolic Risks scenarios) demonstrated an important decrease in the global burden of DALYs in 2050 of 15·4% (13·5–17·5) compared with the reference scenario, with decreases across super-regions ranging from 10·4% (9·7–11·3) in the high-income super-region to 23·9% (20·7–27·3) in north Africa and the Middle East. The Safer Environment scenario had its largest decrease in sub-Saharan Africa (5·2% [3·5–6·8]), the Improved Behavioural and Metabolic Risks scenario in north Africa and the Middle East (23·2% [20·2–26·5]), and the Improved Nutrition and Vaccination scenario in sub-Saharan Africa (2·0% [–0·6 to 3·6]). Interpretation: Globally, life expectancy and age-standardised disease burden were forecasted to improve between 2022 and 2050, with the majority of the burden continuing to shift from CMNNs to NCDs. That said, continued progress on reducing the CMNN disease burden will be dependent on maintaining investment in and policy emphasis on CMNN disease prevention and treatment. Mostly due to growth and ageing of populations, the number of deaths and DALYs due to all causes combined will generally increase. By constructing alternative future scenarios wherein certain risk exposures are eliminated by 2050, we have shown that opportunities exist to substantially improve health outcomes in the future through concerted efforts to prevent exposure to well established risk factors and to expand access to key health interventions

    Educomunicação em Tempos de Pandemia:

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    Os textos que compĂ”em esta obra sĂŁo oriundos do VIII ColĂłquio Ibero-americano de Educomunicação (VIII CIEducom) e IX ColĂłquio Catarinense de Educomunicação (IX CCEducom), realizados em março de 2021. Em um ano no qual o vĂ­rus SARS-CoV-2 e variantes circularam por diversos territĂłrios, Educomunicação em tempos de pandemia: prĂĄticas e desafios foi o tema discutido nos eventos. Este livro colocado Ă  disposição do pĂșblico Ă© um modo de compartilhar caminhos e convidar pessoas curiosas a percorrerem, por meio das palavras e recursos grĂĄficos, desafios identificados e estratĂ©gias para o enfrentamento deste inesperado perĂ­odo de pandemia

    Long‐term care facilities' response to the COVID ‐19 pandemic: An international, cross‐sectional survey

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    Aims To (i) assess the adherence of long‐term care (LTC) facilities to the COVID‐19 prevention and control recommendations, (ii) identify predictors of this adherence and (iii) examine the association between the adherence level and the impact of the pandemic on selected unfavourable conditions. Design Cross‐sectional survey. Methods Managers (n = 212) and staff (n = 2143) of LTC facilities (n = 223) in 13 countries/regions (Brazil, Egypt, England, Hong Kong, Indonesia, Japan, Norway, Portugal, Saudi Arabia, South Korea, Spain, Thailand and Turkey) evaluated the adherence of LTC facilities to COVID‐19 prevention and control recommendations and the impact of the pandemic on unfavourable conditions related to staff, residents and residents' families. The characteristics of participants and LTC facilities were also gathered. Data were collected from April to October 2021. The study was reported following the STROBE guidelines. Results The adherence was significantly higher among facilities with more pre‐pandemic in‐service education on infection control and easier access to information early in the pandemic. Residents' feelings of loneliness and feeling down were the most affected conditions by the pandemic. More psychological support to residents was associated with fewer residents' aggressive behaviours, and more psychological support to staff was associated with less work–life imbalance. Conclusions Pre‐pandemic preparedness significantly shaped LTC facilities' response to the pandemic. Adequate psychological support to residents and staff might help mitigate the negative impacts of infection outbreaks. Impact This is the first study to comprehensively examine the adherence of LTC facilities to COVID‐19 prevention and control recommendations. The results demonstrated that the adherence level was significantly related to pre‐pandemic preparedness and that adequate psychological support to staff and residents was significantly associated with less negative impacts of the pandemic on LTC facilities' staff and residents. The results would help LTC facilities prepare for and respond to future infection outbreaks. Patient or public contribution No Patient or Public Contribution

    Higiene, tipologia da infùncia e institucionalização da criança pobre no Brasil (1875-1899)

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