Introducing Texture: An Open Source WYSIWYG Javascript Editor for JATS

Texture is a WYSIWYG editor app that allows users to turn raw content into structured content, and add as much semantic information as needed for the production of scientific publications. Texture is open source software built on top of Substance (http://substance.io), an advanced Javascript content authoring library. While the Substance library is format agnostic, the Texture editor uses JATS XML as a native exchange format. The Substance library that Texture is built on already supports real-time collaborative authoring, and the easy-to-use WYSIWYG interface would make Texture an attractive alternative to Google Docs. For some editors, the interface could be toggled to more closely resemble a professional XML suite, allowing a user to pop out a raw attribute editor for any given element. Textureauthored documents could then be brought into the journal management system directly, skipping the conversion step, and move straight into a document-centric publishing workflow. &nbsp

Free Research Extension to the iCampus-MIT Online Assessment Tool

Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2003.Includes bibliographical references (p. 57).MIT is currently developing a web-based service for the large-scale assessment of student writing (iMOAT.net). This service contains a database of useful data, particularly texts of student essays that should be available for research and collaboration purposes. In this thesis, I propose a high level design for an interface to the iMOAT system called FREiMOAT that will control access to this research data. This information has the potential to be used by both independent researchers as well as current users of the iMOAT system for self evaluation and collaboration purposes. Current users of the iMOAT system (administrators at a number of schools around the country), have requested the ability to view each others materials so they might improve upon their own assessments. (e.g. SMALL UNIVERSITY would like to see how STATE COLLEGE is able to use the service on larger bodies of students) Independent researchers, on the other hand, might want access to the site for purposes of determining if students from different states perform differently on the same assessments. This interface is responsible for two main tasks; access control and maintaining data anonymity.by Jordan Michael Alperin.M.Eng

Envisioning a World Beyond APCs/BPCs

This archival page includes documents and recordings related to the international symposium, “Envisioning a World Beyond APCs/BPCs,” held in Lawrence, Kansas, on Thursday and Friday, November 17-18. The presenters were a group of 18 internationally respected scholars, publishers, university librarians, and executives from foundations and organizations, who were asked to participate in a discussion about current models available for achieving an expansive, inclusive, and balanced worldwide open publishing ecosystem. The symposium was co-sponsored by the University of Kansas Libraries, Open Access Network (a project of K|N Consultants), Allen Press, SPARC, and ARL. The materials included here are the symposium schedule, recordings of Parts 1 and 2 of the Nov. 17 livestream, a transcript of the livestream, and team proposals originating from the Nov. 18 morning session.This symposium was sponsored by the University of Kansas Libraries, Open Access Network (a project of K|N Consultants), Allen Press, and SPARC

Quantum FHE (Almost) As Secure As Classical

Fully homomorphic encryption schemes (FHE) allow to apply arbitrary efficient computation to encrypted data without decrypting it first. In Quantum FHE (QFHE) we may want to apply an arbitrary quantumly efficient computation to (classical or quantum) encrypted data. We present a QFHE scheme with classical key generation (and classical encryption and decryption if the encrypted message is itself classical) with comparable properties to classical FHE. Security relies on the hardness of the learning with errors (LWE) problem with polynomial modulus, which translates to the worst case hardness of approximating short vector problems in lattices to within a polynomial factor. Up to polynomial factors, this matches the best known assumption for classical FHE. Similarly to the classical setting, relying on LWE alone only implies leveled QFHE (where the public key length depends linearly on the maximal allowed evaluation depth). An additional circular security assumption is required to support completely unbounded depth. Interestingly, our circular security assumption is the same assumption that is made to achieve unbounded depth multi-key classical FHE. Technically, we rely on the outline of Mahadev (arXiv 2017) which achieves this functionality by relying on super-polynomial LWE modulus and on a new circular security assumption. We observe a connection between the functionality of evaluating quantum gates and the circuit privacy property of classical homomorphic encryption. While this connection is not sufficient to imply QFHE by itself, it leads us to a path that ultimately allows using classical FHE schemes with polynomial modulus towards constructing QFHE with the same modulus

Methane Clumped Isotopes: Progress and Potential for a New Isotopic Tracer

The isotopic composition of methane is of longstanding geochemical interest, with important implications for understanding petroleum systems, atmospheric greenhouse gas concentrations, the global carbon cycle, and life in extreme environments. Recent analytical developments focusing on multiply substituted isotopologues (‘clumped isotopes’) are opening a valuable new window into methane geochemistry. When methane forms in internal isotopic equilibrium, clumped isotopes can provide a direct record of formation temperature, making this property particularly valuable for identifying different methane origins. However, it has also become clear that in certain settings methane clumped isotope measurements record kinetic rather than equilibrium isotope effects. Here we present a substantially expanded dataset of methane clumped isotope analyses, and provide a synthesis of the current interpretive framework for this parameter. In general, clumped isotope measurements indicate plausible formation temperatures for abiotic, thermogenic, and microbial methane in many geological environments, which is encouraging for the further development of this measurement as a geothermometer, and as a tracer for the source of natural gas reservoirs and emissions. We also highlight, however, instances where clumped isotope derived temperatures are higher than expected, and discuss possible factors that could distort equilibrium formation temperature signals. In microbial methane from freshwater ecosystems, in particular, clumped isotope values appear to be controlled by kinetic effects, and may ultimately be useful to study methanogen metabolism

Meta-analysis of pre-clinical studies of early decompression in acute spinal cord injury:a battle of time and pressure

The use of early decompression in the management of acute spinal cord injury (SCI) remains contentious despite many pre-clinical studies demonstrating benefits and a small number of supportive clinical studies. Although the pre-clinical literature favours the concept of early decompression, translation is hindered by uncertainties regarding overall treatment efficacy and timing of decompression.We performed meta-analysis to examine the pre-clinical literature on acute decompression of the injured spinal cord. Three databases were utilised; PubMed, ISI Web of Science and Embase. Our inclusion criteria consisted of (i) the reporting of efficacy of decompression at various time intervals (ii) number of animals and (iii) the mean outcome and variance in each group. Random effects meta-analysis was used and the impact of study design characteristics assessed with meta-regression.Overall, decompression improved behavioural outcome by 35.1% (95%CI 27.4-42.8; I(2)=94%, p<0.001). Measures to minimise bias were not routinely reported with blinding associated with a smaller but still significant benefit. Publication bias likely also contributed to an overestimation of efficacy. Meta-regression demonstrated a number of factors affecting outcome, notably compressive pressure and duration (adjusted r(2)=0.204, p<0.002), with increased pressure and longer durations of compression associated with smaller treatment effects. Plotting the compressive pressure against the duration of compression resulting in paraplegia in individual studies revealed a power law relationship; high compressive forces quickly resulted in paraplegia, while low compressive forces accompanying canal narrowing resulted in paresis over many hours.These data suggest early decompression improves neurobehavioural deficits in animal models of SCI. Although much of the literature had limited internal validity, benefit was maintained across high quality studies. The close relationship of compressive pressure to the rate of development of severe neurological injury suggests that pressure local to the site of injury might be a useful parameter determining the urgency of decompression