A novel content-based image retrieval system based on Bayesian logistic regression

In this work, a novel content-based image retrieval (CBIR) method is presented. It has been implemented and run on “Qatris IManager” [14], a system belonging to SICUBO S.L. (spin-off from University of Extremadura, Spain). The system offers some innovative visual content search tools for image retrieval from databases. It searches, manages and classifies images using four kinds of features: colour, texture, shape and user description. In a typical CBIR system, query results are a set of images sorted by feature similarities with respect to the query. However, images with high feature similarities to the query may be very different from the query in terms of semantics. This discrepancy between low-level features and high-level concepts is known as the semantic gap. The search method presented here, is a novel supervised image retrieval method, based in Bayesian Logistic Regression, which uses the information from the characteristics extracted from the images and from the user’s opinion who sets up the search. The procedure of search and learning is based on a statistical method of aggregation of preferences given by Arias-Nicolás et al. [1] and is useful in problems with both a large number of characteristics and few images. The method could be specially helpful for those professionals who have to make a decision based in images, such as doctors to determine the diagnosis of patients, meteorologists, traffic police to detect license plate, etc

Intrinsic structure of two-phonon states in the interacting boson model

A general study of excitations up to two-phonon states is carried out using the intrinsic-state formalism of the Interacting Boson Model (IBM). Spectra and transitions for the different dynamical symmetries are analyzed and the correspondence with states in the laboratory frame is established. The influence of multi-phonon states is discussed. The approach is useful in problems where the complexity of the IBM spectrum renders the analysis in the laboratory frame difficult.Comment: 22 pages, TeX (ReVTeX). 7 eps figures. Submitted to Nucl. Phys.

Boson-conserving one-nucleon transfer operator in the interacting boson model

The boson-conserving one-nucleon transfer operator in the interacting boson model (IBA) is reanalyzed. Extra terms are added to the usual form used for that operator. These new terms change generalized seniority by one unit, as the ones considered up to now. The results obtained using the new form for the transfer operator are compared with those obtained with the traditional form in a simple case involving the pseudo-spin Bose-Fermi symmetry $U^{B}(6) \otimes U^F(12)$ in its $U^{BF}(5) \otimes U^F(2)$ limit. Sizeable differences are found. These results are of relevance in the study of transfer reactions to check nuclear supersymmetry and in the description of (\beta)-decay within IBA.Comment: 13 pages, 1 table, 0 figures. To be published in Phys. Rev.

The optical system of the Tenerife Microwave Spectrometer: a window for observing the 10-20 GHz sky spectra

The TMS optical system is based on a decentered dual-reflector system in a Gregorian configuration to observe with an angular resolution of less than $2^\circ$. The primary goal of the present study is to evaluate the final design and verify that it satisfies the design requirements. We aim for low cross-polarization (-30 dB), low sidelobe (-25 dB) levels, and a stable beam in terms of shape (low ellipticity) and size over a full octave bandwidth (10-20 GHz). We performed both ray-tracing and full-wave simulations using the CST Studio software in order to investigate the system behaviour. We gave special attention to the beam frequency variation and polarization leakage. We have characterized the effects on the radiation pattern produced by the cryostat window. We present the final design of the TMS optical system, as well as a complete study of the system's performance in terms of cross-polarization, sidelobes, ellipticity and beamwidth. We discuss the effects of sidelobes and study the need for a baffle.Comment: 30 pages, 15 figures. Accepted for publication in JINS

A Microwave Blackbody Target for Cosmic Microwave Background Spectral Measurements in the 10-20GHz range

The Tenerife Microwave Spectrometer (TMS) is a ground-based radio-spectrometer that will take absolute measurements of the sky between 10-20 GHz. To ensure the sensitivity and immunity to systematic errors of these measurements, TMS includes an internal calibration system optimised for the TMS band, and cooled down to 4 K. It consists of an Aluminium core, composed of a baseplate and a bed of pyramidal elements coated with an absorber material and a metallic shield. The absorber coating is made of a commercial resin ECCOSORB CR/MF 117. To achieve the high stability (+/- 1 mK/h), temperature homogeneity (thermal gradients {AT = 0.999) requirements of the reference unit, careful consideration has been given to the RF and thermal properties of the materials, as well as their geometry. In summary, this paper presents a comprehensive account of the design, characterisation, and test results of the TMS reference system.Comment: 45 pages, 36 figures, JINS

Caracterización de parámetros reproductivos y endocrinos en una población de conejas ibicencas

El conejo ibicenco o conill pagès d’Eivissa es una población originaria de esta isla que actualmente presenta un escaso número de efectivos, ya que está siendo desplazada por otras razas con mayores rendimientos productivos. La conservación de este tipo de poblaciones precisa de la creación de bancos de germoplasma, con lo que es necesario establecer primeramente sus características reproductivas. Por ello, el objetivo del presente trabajo ha sido caracterizar algunos parámetros reproductivos de hembras ibicencas y compararlos con el cruce comercial de California x Neozelandés blanco, que es el habitualmente utilizado en cunicultura para producción. La fertilidad obtenida fue similar en ambos grupos, siendo de un 76,8% y de un 81,3% para las conejas híbridas e ibicencas, respectivamente. La prolificidad, el peso de la camada a 21 días de vida, la producción de leche, el número de gazapos destetados, el peso de la camada al destete y su ganancia media diaria fue superior en los cruces comerciales que en la población ibicenca, presentando ésta última una mayor duración de la gestación y un mayor peso individual al destete. Los ibicencos tardaron un par de días más en alcanzar el peso de sacrificio que los híbridos comerciales, puesto que su ganancia media diaria fue menor y el índice de conversión fue siempre superior, salvo en la última semana que disminuyó y se equiparó al de los híbridos. Respecto a los parámetros endocrinos, tanto las concentraciones de LH como las de progesterona post-ovulación fueron superiores para las hembras híbridas comerciales. finalmente, los datos de caracterización de la respuesta ovárica muestran que las hembras de cruce comercial presentaron un mayor número de folículos preovulatorios y de oocitos por ovario, así como un mayor número de cuerpos lúteos y embriones recuperados, que presentaron además una mayor velocidad de desarrollo embrionario, que las ibicencas. Por tanto, se ha comprobado experimentalmente que el conejo ibicenco, al ser una especie rústica, no seleccionada, presenta características reproductivas menos mejoradas que las de los cruces comerciales, si bien sigue siendo importante su conservación desde el punto de vista del mantenimiento de la biodiversidad genética

Funcionamiento de la escala de intensidad de apoyos en niños y adolescentes con autismo

Funcionamiento de la escala de intensidad e apoyos SIS-C específicamente en personas con TEA

Novel Mutation Hotspots within Non-Coding Regulatory Regions of the Chronic Lymphocytic Leukemia Genome

Mutations in non-coding DNA regions are increasingly recognized as cancer drivers. These mutations can modify gene expression in cis or by inducing high-order chormatin structure modifications with long-range effects. Previous analysis reported the detection of recurrent and functional non-coding DNA mutations in the chronic lymphocytic leukemia (CLL) genome, such as those in the 3' untranslated region of NOTCH1 and in the PAX5 super-enhancer. In this report, we used whole genome sequencing data produced by the International Cancer Genome Consortium in order to analyze regions with previously reported regulatory activity. This approach enabled the identification of numerous recurrently mutated regions that were frequently positioned in the proximity of genes involved in immune and oncogenic pathways. By correlating these mutations with expression of their nearest genes, we detected significant transcriptional changes in genes such as PHF2 and S1PR2. More research is needed to clarify the function of these mutations in CLL, particularly those found in intergenic regions

Electronic structure analysis of the quasi-one-dimensional oxide Sr6Co5O15 within the LDA+U method

The quasi-one-dimensional cobalt oxide Sr6Co5O15 is studied using first-principles electronic-structure calculations and Boltzmann transport theory. We have been able to describe the electronic structure, characterized by the structural one-dimensionality and a particular type of charge ordering, with unexpected electronic structure of the different Co atoms. The origin of the large unquenched misaligned orbital angular momenta comes out naturally from a correct description of the different crystal-field environments. The evolution with the on-site Coulomb repulsion (U) of the electronic structure and the transport properties is discussed, with a best agreement with experiment found for the smallest value of U that allows to converge the correct in-chain ferrimagnetic ground stateThe authors thank the CESGA for the computing facilities, the Ministerio de Educación y Ciencia (MEC) for the financial support through the project MAT2009-08165, the Ministerio de Ciencia e Innovación (MICINN) for the project MAT2007-60536 and the Xunta de Galicia for the project INCITE08PXIB236052PR. A.S.B. thanks MEC for a FPU grant. M.P. and J.B. thank Isabel Barreto program and Deputación da Coruña, respectively, for financial supportS

Interactions between Nodal and Wnt signalling Drive Robust Symmetry-Breaking and Axial Organisation in<i>Gastruloids</i>(Embryonic Organoids)

Generation of asymmetry within the early embryo is a critical step in the establishment of the three body axes, providing a reference for the patterning of the organism. To study the establishment of asymmetry and the development of the anteroposterior axis (AP) in culture, we utilised our ‘ Gastruloid ’ model system. ‘ Gastruloids ’, highly reproducible embryonic organoids formed from aggregates of mouse embryonic stem cells, display symmetry-breaking, polarised gene expression and axial development, mirroring the processes on a time-scale similar to that of the mouse embyro. Using Gastruloids formed from mouse ESCs containing reporters for Wnt, FGF and Nodal signalling, we were able to quantitatively assess the contribution of these signalling pathways to the establishment of asymmetry through single time-point and live-cell fluorescence microscopy. During the first 24-48h of culture, interactions between the Wnt/ β -Catenin and Nodal/TGF/ β signalling pathways promote the initial symmetry-breaking event, manifested through polarised Brachyury (T/Bra) expression. Neither BMP nor FGF signalling is required for the establishment of asymmetry, however Wnt signalling is essential for the amplification and stability of the initial patterning event. Additionally, low, endogenous levels of FGF (24-48h) has a role in the amplification of the established pattern at later time-points. Our results confirm that Gastruloids behave like epiblast cells in the embryo, leading us to translate the processes and signalling involved in pattern formation of Gastruloids in culture to the development of the embryo, firmly establishing Gastruloids as a highly reproducible, robust model system for studying cell fate decisions and early pattern formation in culture