Creación de una empresa de neurorehabilitación.

Administración y Dirección de Empresa

Alimony and family housing in marital crisis with children of age

En el presente trabajo, se alude a la protección de los hijos mayores de edad en crisis matrimoniales. Analizaremos diversidad de supuestos donde los hijos comunes tras haber cumplido la mayoría de edad, el Código Civil no recoge con exactitud las cuestiones referidas a la pensión de alimentos y a la vivienda familiar. El estudio de dicho trabajo se realiza desde una perspectiva objetiva, dejando a un lado las opiniones personales. La finalidad de este trabajo consiste en mostrar al lector que, en la mayoría de los casos de hijos mayores de edad, no hay una norma en concreto para determinar una solución, ya que dependerá de cada supuesto y de cada situación personal en la que se encuentren tanto los hijos como los progenitores. La mejor manera de solventar dichas cuestiones es llegar a acuerdos para facilitar tanto la vida de los progenitores como de los hijos mayores de edad.The aim of this paper, the protection of adult children in marital crisis is alluded to. We will analyze a variety of cases where the common children after having reached the age of majority, the Civil Code doesn´t accuralety include the issues related to alimony and family housing. The study of this paper is done from an objective perspective, leaving aside personal opinions. The purpose of this paper is to show the reader that in most cases of children of legal age, there is no specific rule to determine a solution, it will depend on each case and each personal situation in which both the children and the parents find themselves. The best way of solve these problems is to reach agreements to make life easier for both parents and children of age.Máster Universitario en Acceso a la Profesión de Abogado (M155

Implant-Supported Fixed Partial Dentures with Posterior Cantilevers: In Vitro Study of Mechanical Behavior

Rehabilitation with dental implants is not always possible due to the lack of bone quality or quantity, in many cases due to bone atrophy or the morbidity of regenerative treatments. We find ourselves in situations of performing dental prostheses with cantilevers in order to rehabilitate our patients, thus simplifying the treatment. The aim of this study was to analyze the mechanical behavior of four types of fixed partial dentures with posterior cantilevers on two dental implants (convergent collar and transmucosal internal connection) through an in vitro study (compressive loading and cyclic loading). This study comprised four groups (n = 76): in Group 1, the prosthesis was screwed directly to the implant platform (DS; n = 19); in Group 2, the prosthesis was screwed to the telescopic interface on the implant head (INS; n = 19); in Group 3, the prosthesis was cemented to the telescopic abutment (INC; n = 19); and in Group 4, the prosthesis was cemented to the abutment (DC; n = 19). The sets were subjected to a cyclic loading test (80 N load for 240,000 cycles) and compressive loading test (100 KN load at a displacement rate of 0.5 mm/min), applying the load until failure occurred to any of the components at the abutment–prosthesis–implant interface. Subsequently, an optical microscopy analysis was performed to obtain more data on what had occurred in each group. Results: Group 1 (direct screw-retained prosthesis, DS) obtained the highest mean strength value of 663.5 ± 196.0 N. The other three groups were very homogeneous: 428.4 ± 63.1 N for Group 2 (INS), 486.7 ± 67.8 N for Group 3 (INC), and 458.9 ± 38.9 N for Group 4 (DC). The mean strength was significantly dependent on the type of connection (p < 0.001), and this difference was similar for all of the test conditions (cyclic and compressive loading) (p = 0.689). Implant-borne prostheses with convergent collars and transmucosal internal connections with posterior cantilevers screwed directly to the implant connection are a good solution in cases where implant placement cannot avoid extensions.Odontologí

Teoría de Situación Específica de Factores Protectores Socio Ecológicos del Consumo de Alcohol en Jóvenes Universitarios

Introducción: las Teorías de Situación Específica (TSE) abordan un fenómeno relativamente concreto y específico que permite describir, explicar y predecir como ocurre. Su principal función es proporcionar una estructura y una guía para la interpretación de comportamientos, procesos, respuestas humanas y eventos inicialmente desconcer-tantes. Objetivo: generar una TSE que explique los factores protectores socio ecológicos del consumo de alcohol en jóvenes universitarios, producto del análisis del Modelo Socio Ecológico (MSE) de McLeroy. Metodología: se utilizó la estructura Conceptual-Teórico-Empírico (C-T-E) propuesto por Fawcett, el cual consiste en cinco pasos 1) identifi-cación de conceptos, 2) clasificación de los conceptos, 3) identificación y clasificación de las proposiciones, 4) orden jerárquico de proposiciones y 5) construcción del diagrama. Resultados: la TSE es el resultado de la estructura C-T-E, contribuye a la identificación de un fenómeno específico de la disciplina, determina conceptos, relaciones y posibles efectos de los factores protectores sobre la conducta del consumo de alcohol. Conclusión: el método fue apropiado para construir la Teoría de Situación Específica ya que permitió su desarrollo teniendo una base conceptual, teórica e indicadores empíricos con los cuales los conceptos (variables) pueden ser medidos en diversos contextos (inves-tigación y práctica).Introduction: Situation-Specific Theories (SST) address a relatively concrete and specific phenomenon that allow describing, explaining and predicting how it occurs. Their main function is to provide a structure and a guidance for the interpretation of initially puzzling behaviors, processes, human responses and events. Objective: to generate a SST that explains the socio-ecological protective factors of alcohol consumption in young university students based on the analysis of McLeroy’s Socio-Ecological Model (SEM). Methodology: the Conceptual-Theoretical-Empirical (C-T-E) structure proposed by Fawcett was used, which consists of five steps 1) identification of concepts, 2) classi-fication of concepts, 3) identification and classification of propositions, 4) hierarchical order of propositions and 5) construction of the diagram. Results: the SST is the result of the C-T-E structure, contributes to the identification of a discipline-specific phenomenon, and determines concepts, relationships and possible effect of protective factors on drinking behavior. Conclusion: the method was appropriate to build the Situation-Specific Theory as it allowed its development having a conceptual and theoretical basis and empirical indicators with which the concepts (variables) can be measured in different contexts (research and practice)

Validation of predicting transfer instruments in Spain

Purpose: The purpose of this paper is to validate two scales, the factors predicting transfer (FPT) and the effectiveness questionnaire (CdE), in the Spanish Public Administration (SPA). Design/methodology/approach: The FPT was administered at the end of the training, and the CdE four months after training. Participants had attended one of the 62 trainings offered by the SPA. With 1,457 participants, exploratory factor analysis (EFA; n = 728) and confirmatory factory analysis (CFA) (n = 729), randomly assigned, were performed on the FPT, and CFA (n = 726) was applied to the CdE. Findings: A 30-item and four-factor solution emerged for the FPT through the EFA, which was confirmed by a good model fit through the CFA. A seven-item single-factor solution was confirmed for the CdE. Measurement invariance for the mode of instruction and gender was accepted for both instruments. Research limitations/implications: Further research should be done in a more heterogenous sample that includes private organizations, different sectors and sizes. In the human resource development (HRD) field, these results suggest, in line with previous research, the existence of underlying constructs of factors of transfer that migrate across cultures. Practical implications: The potential use of the FPT is the diagnosis of factors of transfer, and for the CdE, evaluation of the transfer of interventions at the behavioral level. The instruments are suitable for research and practice that compares online and in-class training. Originality/value: The study performs the first rigorous analysis of measurement instruments to evaluate factors that predict transfer in Spain.2019-2

Erythrocyte Membrane Nanomechanical Rigidity Is Decreased in Obese Patients

This work intends to describe the physical properties of red blood cell (RBC) membranes in obese adults. The hypothesis driving this research is that obesity, in addition to increasing the amount of body fat, will also modify the lipid composition of membranes in cells other than adipocytes. Forty-nine control volunteers (16 male, 33 female, BMI 21.8 ± 5.6 and 21.5 ± 4.2 kg/m2, respectively) and 52 obese subjects (16 male and 36 female, BMI 38.2± 11.0 and 40.7 ± 8.7 kg/m2, respectively) were examined. The two physical techniques applied were atomic force microscopy (AFM) in the force spectroscopy mode, which allows the micromechanical measurement of penetration forces, and fluorescence anisotropy of trimethylammonium diphenylhexatriene (TMA-DPH), which provides information on lipid order at the membrane polar–nonpolar interface. These techniques, in combination with lipidomic studies, revealed a decreased rigidity in the interfacial region of the RBC membranes of obese as compared to control patients, related to parallel changes in lipid composition. Lipidomic data show an increase in the cholesterol/phospholipid mole ratio and a decrease in sphingomyelin contents in obese membranes. ω-3 fatty acids (e.g., docosahexaenoic acid) appear to be less prevalent in obese patient RBCs, and this is the case for both the global fatty acid distribution and for the individual major lipids in the membrane phosphatidylcholine (PC), phosphatidylethanolamine (PE) and phosphatidylserine (PS). Moreover, some ω-6 fatty acids (e.g., arachidonic acid) are increased in obese patient RBCs. The switch from ω-3 to ω-6 lipids in obese subjects could be a major factor explaining the higher interfacial fluidity in obese patient RBC membranes.This work was supported in part by the Basque Government Department of Economic Development, grant No. KK-2019/00028 (OBINTER); the Basque Government Department of Education, grants No. IT1264-19, IT1281-19, IT1270-19, and IT1625-22; the Basque Government Department of Health, grants No. 2019-222030, 2020-333023; Fundación Ramón Areces; and by Centre for the Development of Industrial Technology (CDTI) of the Spanish Ministry of Science and Innovation under the grant agreement: TECNOMIFOOD project (CER-20191010) and Basque Government: IT1625-22

Co-construcción del conocimiento en GrupoLab

En este proyecto pretende dar respuesta a la necesidad de crear sinergias académicas entre alumnado, personal docente e investigador y usuarios de proyectos, cuyo punto en común es el interés en la investigación social y el trabajo social, en concreto en la intervención con grupos. Asimismo, da respuesta a la necesidad del alumnado de crear espacios de aprendizaje donde desarrollar propuestas que favorezcan el impulso de la carrera universitaria y donde se pueda colaborar de forma horizontal con otras personas de forma que se potencie la creatividad y la iniciativa

Delayed viral clearance despite high number of activated T cells during the acute phase in Argentinean patients with hantavirus pulmonary syndrome

Background: The hallmarks of HPS are increase of vascular permeability and endothelial dysfunction. Although an exacerbated immune response is thought to be implicated in pathogenesis, clear evidence is still elusive. As orthohantaviruses are not cytopathic CD8+ T cells are believed to be the central players involved in pathogenesis. Methods: Serum and blood samples from Argentinean HPS patients were collected from 2014 to 2019. Routine white blood cell analyses, quantification and characterization of T-cell phenotypic profile, viral load, neutralizing antibody response and quantification of inflammatory mediators were performed. Findings: High numbers of activated CD4+ and CD8+ T cells were found in all HPS cases independently of disease severity. We found increased levels of some proinflammatory mediators during the acute phase of illness. Nonetheless, viral RNA remained high, showing a delay in clearance from blood up to late convalescence, when titers of neutralizing antibodies reached a high level. Interpretation: The high activated phenotypic profile of T cells seems to be unable to resolve infection during the acute and early convalescent phases, and it was not associated with the severity of the disease. Thus, at least part of the activated T cells could be induced by the dysregulated inflammatory response in an unspecific manner. Viral clearance seems to have been more related to high titers of neutralizing antibodies than to the T-cell response. Funding: This work was supported mainly by the Administración Nacional de Laboratorios e Institutos de Salud (ANLIS) “Dr. Carlos Malbrán”. Further details of fundings sources is included in the appendix.Fil: Iglesias, Ayelén Aluminé. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán"; ArgentinaFil: Periolo, Natalia. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Bellomo, Carla María. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán"; ArgentinaFil: Lewis, Lorena Cecilia. Provincia del Chubut. Servicio de Salud Mental. Hospital Zonal de Esquel; ArgentinaFil: Olivera, Camila Paula. Provincia del Chubut. Servicio de Salud Mental. Hospital Zonal de Esquel; ArgentinaFil: Rosario Anselmo, Constanza. Provincia del Chubut. Servicio de Salud Mental. Hospital Zonal de Esquel; ArgentinaFil: García, Marina. Karolinska Huddinge Hospital. Karolinska Institutet; SueciaFil: Coelho, Rocío María. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán"; ArgentinaFil: Alonso, Daniel Oscar. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán"; ArgentinaFil: Dighero Kemp, Bonnie. National Institute Of Allergy And Infectious Diseases; Estados UnidosFil: Sharma, Heema. National Institute Of Allergy And Infectious Diseases; Estados UnidosFil: Kuhn, Jens H.. National Institute Of Allergy And Infectious Diseases; Estados UnidosFil: Di Paola, Nicholas. Center For Genome Sciences, U.s. Army Medical Research; Estados UnidosFil: Sanchez Lockhart, Mariano. Center For Genome Sciences, U.s. Army Medical Research; Estados UnidosFil: Palacios, Gustavo. Center For Genome Sciences, U.s. Army Medical Research; Estados UnidosFil: Schierloh, Luis Pablo. Universidad Nacional de Entre Ríos. Instituto de Investigación y Desarrollo en Bioingeniería y Bioinformática - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Investigación y Desarrollo en Bioingeniería y Bioinformática; ArgentinaFil: Martinez, Valeria Paula. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbrán"; Argentin

Association Between Insulin‐Like Growth Factor‐1 and Social Cognition in Huntington's Disease

Insulin-like growth factor 1 (IGF-1) seems to be involved in the neural circuits associated with social cognition and brain structure.Study funded by Gerencia Regional de Salud de Castilla y Leon (Sacyl GRS 1768/A/18)