151 research outputs found

    Effects of Acute Eccentric Exercise on Appetite-Related Hormones and Food Preferences in Men

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    Eccentric exercise has been suggested to improve muscle atrophy, muscle function, and insulin sensitivity. The aim of this study was to examine the effect of acute eccentric exercise on appetite-related hormones, food preferences, and food intake. Fourteen moderately active men were recruited to participate in this study (age 24.2 ± 5.5 years; BMI 23.4 ± 3.3 kg/m2; VO2max 48.9 ± 3.1 ml/kg/min). Three different conditions were implemented; no exercise, flat running “inclination 0” and downhill running “inclination –12%.” Appetite-related hormones, subjective appetite sensations, food preference and reward, and ad libitum food intake were measured at pre-, immediately post-, and 24 h post exercise.There were no significant median changes in total ghrelin or pancreatic peptide concentrations between conditions. There were also no median differences in subjective appetite ratings or energy intake between conditions, but the median change in explicit liking of sweet versus savory foods differed significantly between pre-exercise and 24 h post exercise (p = .013). Post-hoc analysis observed a significant difference in the pre-exercise to 24 h post exercise change between front running and downhill running (p = .023), and indicated greater liking of savory foods over sweet foods in downhill running than front running. However, no further differences were seen between conditions for the remaining food preference parameters, suggesting there were no systematic trends in these data. In conclusion, there was no effect of front and downhill running on eating behavior as compared to a nonexercise control condition, but these data need to be replicated in a larger and more heterogeneous sample

    Ultrasound-based techniques as alternative treatments for chronic wounds: A comprehensive review of clinical applications

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    Ultrasound (US) waves have been recently developed for the treatment of different chronic wounds with promising therapeutic outcomes. However, the clinical efficacy of these techniques is still not fully understood and standard guidelines on dose ranges and possible side effects should be determined. This paper aims to comprehensively review the recent advances in US techniques for chronic wound treatment, their therapeutic efficacies, and clinical considerations and challenges. The databases of PubMed (1985-2017), EMBASE (1985-2017), Web of Sciences (1985-2017), Cochrane central library (1990-2017), and Google Scholar (1980-2017) were searched using the set terms. The obtained results were screened for the title and abstract by two authors and the relevant papers were reviewed for further details. Preclinical and clinical studies have shown strong evidence on the therapeutic efficiency of US in chronic wounds. The main limitation on developing clinical standard protocols of US for treatment of wounds is the lack of definite dose-response for each wound. However, spatial average temporal average is the main parameter for defining US dosage in wound treatment. The range of 0.5 to 3 W/cm2 is a range of dose exerting significant therapeutic outcomes and minimum adverse effects. Low-frequency US waves can accelerate the healing speed of open wounds as well as deep-tissue injuries. In addition, US waves show promising therapeutic efficacy for chronic wounds. To develop clinical US protocol for each wound type, further in vitro and in vivo preclinical and clinical trials are needed to reach an exact dose-response for each wound type

    ADSORPTION OF FOOD COLORING ALLURA RED DYE (E129) FROM AQUEOUS SOLUTIONS USING ACTIVATED CARBON

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    The adsorption behavior of Allura red (E129) from aqueous solutions onto activated carbon was successfully investigated. All factors affecting the adsorption process were carefully studied and the conditions were optimized. Adsorption of E129 onto activated carbon was found to increase by decreasing the mass of activated carbon, pH and ionic strength of the solution and by increasing temperature. The adsorption capacity of the activated carbon for Allura red was relatively high. Under the optimum conditions, the maximum adsorption capacity for E129 dye was 72.85 mg/g. Three adsorption models; Langmuir, Freundlich and Temkin model were investigated regarding the adsorption of E129. The modelsñ€ℱ parameters KL, qm, R2, (n) were determined and found to be 0.0222, 72.85 mg/g, 0.9057-0.9984, and 0.992, respectively. Also, pseudo first and second-order kinetic models were tested to determine the best-fit model to the adsorption of E129 dye onto activated carbon. The results showed that the adsorption of E129 onto activated carbon obeyed both the Freundlich isotherm and pseudo second-order kinetic models. Moreover, thermodynamic studies indicated that the adsorption of E129 dye onto the activated carbon was spontaneous.Â

    Intelligent Optimization Systems for MaintenanceScheduling of Power Plant Generators

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    This paper presents a Genetic Algorithm (GA) and Ant-Colony (AC) optimization model for power plant generators’ maintenance scheduling. Maintenance scheduling of power plant generators is essential for ensuring the reliability and economic operation of a power system. Proper maintenance scheduling prolongs the shelf life of the generators and prevents unexpected failures. To reduce the cost and duration of generator maintenance, these models are built with various constants, fitness functions, and objective functions. The Analytical Hierarchy Process (AHP), a decision-making tool, is implemented to aid the researcher in prioritizing and re-ranking the maintenance activities from the most important to the least. The intelligent optimization models are developed using MATLAB and the developed intelligent algorithms are tested on a case study in a coal power plant located at minjung, Perak, Malaysia. The power plant is owned and operated by Tenaga Nasional Berhad (TNB), the electric utility company in peninsular Malaysia. The results show that GA outperforms ACO since it reduces maintenance costs by 39.78% and maintenance duration by 60%. The study demonstrates that the proposed optimization method is effective in reducing maintenance time and cost while also optimizing power plant operation

    Multi Criteria Optimization Approach for Dressing of Vitrified Grinding Wheel

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    Rotary diamond dressers are widely used for the dressing to improve the efficiency of vitrified grinding wheel. The paper focuses on the process parameters, i.e., feed speed of dresser, depth of cut, grinding wheel velocity, velocity ratio between grinding wheel and rotary dresser, number of pass and dressing method (up-cut or down-cut) in rotary diamond dressing. The objective is to investigate the effect of these process parameters with their interactions for two response parameters, dressing ratio and overlapped dressed area. As far as the response parameters are concerned, the goal is to maximize dressing ratio and minimize overlapped dressed area simultaneously. Thirty-six experiments were designed and performed. Analysis of variance and multi-criteria optimization approach are opted to find out significant process parameters and optimal parameter setting. Finally, the significant process parameters, dressing method and number of pass are identified as well and the optimal parameter setting is also determined

    Parathyroid hormone secretion and receptor expression determine the age-related degree of osteogenic differentiation in dental pulp stem cells

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    Objective: To demonstrate the levels of parathyroid hormone secretion and genetic expres-sions of parathyroid hormone (PTH) and PTH1 receptor (PTH1R) genes in the dental pulp stem cells (DPSCs) from different age groups before and after induction of osteogenic differentiation. In addition, we also wanted to check their correlation with the degree of osteogenic differentiation. Methods: Human primary DPSCs from three age groups (milk tooth (SHEDs), 7–12 years old; young DPSCs (yDPSCs), 20–40 years old; old DPSCs (oDPSCs), 60+ years old) were characterized for mesenchymal stem cell (MSC) markers. DPSCs were subjected to osteogenic differentiation and functional staining. Gene expression levels were analyzed by qRT-PCR. Surface receptor analysis was done by flow cytometry. Comparative protein levels were evaluated by ELISA. Results: All SHEDs, yDPSCs, and oDPSCs were found to be expressing mesenchymal stem cell markers. SHEDs showed more mineralization than yDPSCs and oDPSCs after osteogenic induction. SHEDs exhibited higher expression of PTH and PTH1R before and after osteogenic induction, and after osteogenic induction, SHEDs showed more expression for RUNX2, ALPL, and OCN. Higher levels of PTH were observed in SHEDs and yDPSCs, and the number of PTH1R positive cells was relatively lower in yDPSCs and oDPSCs than in SHEDs. After osteogenic induction, SHEDs were superior in the secretion of OPG, and the secretions of ALPL and PTH and the number of PTH1R positive cells were relatively low in the oDPSCs. Conclusions: The therapeutic quality of dental pulp stem cells is largely based on their ability to retain their stemness characteristics. This study emphasizes the criterion of aging, which affects the secretion of PTH by these cells, which in turn attenuates their osteogenic potential

    Evaluation of air-gap stacked capacitive antennas for lightning remote sensing

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    This paper evaluates the capacitive antenna performance (sensitivity and frequency shifting) as a lightning sensor in different antenna design structures. Two experiments were carried out, Experiment A - using two different structure antennas, an A3 size capacitive antenna and a quarter A4- sized capacitive antenna, capturing the electric field (E-field) generated by the small spark at a distance of 1 meter away from both antennas. The results were taken in a ratio form of the 1st pulse amplitude captured by quarter A4 size antenna verses 1st pulse amplitude of the waveform captured by A3 antenna for each corresponding spark. Same set up and measurement were taken during the Experiment B except for the quarter A4 size antenna was now being slotted with 6 copper plates were slotted within the gap between the top plate and bottom plate. The result from Experiment A showed an average ratio at 0.1957 with a range of 0.0333 to 0.3085 while the results of Experiment B showed the average value laid at 0.2606 within the range of 0.1581 to 0.4510. The comparison results of Experiment A with Experiment B gave an increment of the sensitivity of the quarter A4 antenna from no stack to fully stacked antenna. However, there was also a significant frequency shifting of the quarter A4 antenna with the change of antenna structure (15% for quarter A4 capacitive antenna without stack; 20% for quarter A4 stacked capacitive antenna)

    Global patterns in endemicity and vulnerability of soil fungi

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    Fungi are highly diverse organisms, which provide multiple ecosystem services. However, compared with charismatic animals and plants, the distribution patterns and conservation needs of fungi have been little explored. Here, we examined endemicity patterns, global change vulnerability and conservation priority areas for functional groups of soil fungi based on six global surveys using a high-resolution, long-read metabarcoding approach. We found that the endemicity of all fungi and most functional groups peaks in tropical habitats, including Amazonia, Yucatan, West-Central Africa, Sri Lanka, and New Caledonia, with a negligible island effect compared with plants and animals. We also found that fungi are predominantly vulnerable to drought, heat and land-cover change, particularly in dry tropical regions with high human population density. Fungal conservation areas of highest priority include herbaceous wetlands, tropical forests, and woodlands. We stress that more attention should be focused on the conservation of fungi, especially root symbiotic arbuscular mycorrhizal and ectomycorrhizal fungi in tropical regions as well as unicellular early-diverging groups and macrofungi in general. Given the low overlap between the endemicity of fungi and macroorganisms, but high conservation needs in both groups, detailed analyses on distribution and conservation requirements are warranted for other microorganisms and soil organisms

    Global patterns in endemicity and vulnerability of soil fungi

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    Fungi are highly diverse organisms, which provide multiple ecosystem services. However, compared with charismatic animals and plants, the distribution patterns and conservation needs of fungi have been little explored. Here, we examined endemicity patterns, global change vulnerability and conservation priority areas for functional groups of soil fungi based on six global surveys using a high-resolution, long-read metabarcoding approach. We found that the endemicity of all fungi and most functional groups peaks in tropical habitats, including Amazonia, Yucatan, West-Central Africa, Sri Lanka, and New Caledonia, with a negligible island effect compared with plants and animals. We also found that fungi are predominantly vulnerable to drought, heat and land-cover change, particularly in dry tropical regions with high human population density. Fungal conservation areas of highest priority include herbaceous wetlands, tropical forests, and woodlands. We stress that more attention should be focused on the conservation of fungi, especially root symbiotic arbuscular mycorrhizal and ectomycorrhizal fungi in tropical regions as well as unicellular early-diverging groups and macrofungi in general. Given the low overlap between the endemicity of fungi and macroorganisms, but high conservation needs in both groups, detailed analyses on distribution and conservation requirements are warranted for other microorganisms and soil organisms

    Global patterns in endemicity and vulnerability of soil fungi

    Get PDF
    Fungi are highly diverse organisms, which provide multiple ecosystem services. However, compared with charismatic animals and plants, the distribution patterns and conservation needs of fungi have been little explored. Here, we examined endemicity patterns, global change vulnerability and conservation priority areas for functional groups of soil fungi based on six global surveys using a high-resolution, long-read metabarcoding approach. We found that the endemicity of all fungi and most functional groups peaks in tropical habitats, including Amazonia, Yucatan, West-Central Africa, Sri Lanka, and New Caledonia, with a negligible island effect compared with plants and animals. We also found that fungi are predominantly vulnerable to drought, heat and land-cover change, particularly in dry tropical regions with high human population density. Fungal conservation areas of highest priority include herbaceous wetlands, tropical forests, and woodlands. We stress that more attention should be focused on the conservation of fungi, especially root symbiotic arbuscular mycorrhizal and ectomycorrhizal fungi in tropical regions as well as unicellular early-diverging groups and macrofungi in general. Given the low overlap between the endemicity of fungi and macroorganisms, but high conservation needs in both groups, detailed analyses on distribution and conservation requirements are warranted for other microorganisms and soil organisms
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