145 research outputs found

    Issues with Voluntary Reporting by Train Drivers and Their Impact on the Railway

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    For organisations to take preventive measures and eliminate potential accidents, the information gained through voluntary reporting is essential. Employees do not, however, report voluntarily for a number of reasons. In this study, we examine why train drivers, who are vital to maintaining rail safety, fail to report hazardous occurrences, leading to employee silence. The measurement tool, which has already been developed specifically for aviation employees, has been applied to 346 train drivers working on Turkish Railways. The scale used for research purposes has proven to be valid and reliable for organisations involved in railways. As a result, it was determined that the drivers did not participate in voluntary reporting due to relational and prosocial, disengaged, quiescence and acquiescence and fear and defensive factors. The highest score for the reasons for non-reporting was observed in the dimension of quiescence and acquiescence. The results of the correlation analysis between dimensions, which are assumed to be the reasons for non-reporting, point to strong positive relationships between each dimension

    Thrombospondin-1 and VEGF in inflammatory bowel disease

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    Background and aim: Angiogenesis is an important process in the pathogenesis of chronic inflammation. We aimed to study the angiogeneic balance in inflammatory bowel disease (IBD) by evaluating the expression of vascular endothelial growth factor (VEGF) and thrombospondin-1 (TSP-1) on colonic epithelial cells, together with the expression of inducible nitric oxide synthase (iNOS). Methods: Twenty-one ulcerative colitis (UC), 14 Crohn’s disease (CD), 11 colorectal cancer patients, and 11 healthy controls colonic biopsy samples were evaluated immunohistochemically. Results: The expressions of TSP-1, VEGF, and iNOS in UC and CD groups were higher than expression in healthy control group, all with statistical significance. However, in colorectal cancer group, VEGF and iNOS expressions were increased importantly, but TSP-1 expression was not statistically different from healthy control group’s expression. Both TSP-1 and VEGF expressions were correlated with iNOS expression distinctly but did not correlate with each other. Conclusions: Both pro-angiogeneic VEGF and antiangiogeneic TSP-1 expressions were found increased in our IBD groups, but in colorectal cancer group, only VEGF expression was increased. TSP-1 increases in IBD patients as a response to inflammatory condition, but this increase was not enough to suppress pathologic angiogenesis and inflammation in IBD.Keywords: inflammatory bowel disease; thrombospondin-1; VEGF; iNOS; colon cance

    Uterine primitive neuroectodermal tumor with adenosarcoma: a case report

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    <p>Abstract</p> <p>Introduction</p> <p>Primitive neuroectodermal tumor of the uterus is extremely rare. They occur as either pure primitive neuroectodermal tumors or admixed with neoplasms of mullerian origin.</p> <p>Case presentation</p> <p>A case of uterine primitive neuroectodermal tumor with adenosarcoma in a 50-year-old Asian Indian woman is presented. Histologically, the neoplasm displayed perivascular pseudorosettes and occasional Homer-Wright rosettes. A strong positivity for neuronspecific enolase and synaptophysin was noted, while chromogranin and CD99 were negative. Merging imperceptibly with the neuroectodermal components were the areas of adenosarcoma.</p> <p>Conclusion</p> <p>To the best of our knowledge, this report represents the second case of a uterine primitive neuroectodermal tumor with an admixed adenosarcoma.</p

    Clinical presentation of abdominal tuberculosis in HIV seronegative adults

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    BACKGROUND: The accurate diagnosis of abdominal tuberculosis usually takes a long time and requires a high index of suspicion in clinic practice. Eighty-eight immune-competent patients with abdominal tuberculosis were grouped according to symptoms at presentation and followed prospectively in order to investigate the effect of symptomatic presentation on clinical diagnosis and prognosis. METHODS: Based upon the clinical presentation, the patients were divided into groups such as non-specific abdominal pain & less prominent in bowel habit, ascites, alteration in bowel habit, acute abdomen and others. Demographic, clinical and laboratory features, coexistence of pulmonary tuberculosis, diagnostic procedures, definitive diagnostic tests, need for surgical therapy, and response to treatment were assessed in each group. RESULTS: According to clinical presentation, five groups were constituted as non-specific abdominal pain (n = 24), ascites (n = 24), bowel habit alteration (n = 22), acute abdomen (n = 9) and others (n = 9). Patients presenting with acute abdomen had significantly higher white blood cell counts (p = 0.002) and abnormalities in abdominal plain radiographs (p = 0.014). Patients presenting with alteration in bowel habit were younger (p = 0.048). The frequency of colonoscopic abnormalities (7.5%), and need for therapeutic surgery (12.5%) were lower in patients with ascites, (p = 0.04) and (p = 0.001), respectively. There was no difference in gender, disease duration, diagnostic modalities, response to treatment, period to initial response, and mortality between groups (p > 0.05). Gastrointestinal tract alone was the most frequently involved part (38.5%), and this was associated with acid-fast bacteria in the sputum (p = 0.003). CONCLUSION: Gastrointestinal tract involvement is frequent in patients with active pulmonary tuberculosis. Although different clinical presentations of patients with abdominal tuberculosis determine diagnostic work up and need for therapeutic surgery, evidence based diagnosis and consequences of the disease does not change

    Quality standards in upper gastrointestinal endoscopy: a position statement of the British Society of Gastroenterology (BSG) and Association of Upper Gastrointestinal Surgeons of Great Britain and Ireland (AUGIS)

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    AVRUPA BİRLİĞİ'NDE KOOPERATİF BANKACILIĞI VE TÜRKİYE'DE UYGULANABİLİRLİĞİ

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    Kooperatifler, bireylerin tek başlarına yapamayacakları işleri yapabilmek için gönüllü olarak bir araya gelerek oluşturdukları demokratik sistemdir. Kooperatifler, belirli gruplar tarafından kendi aralarında işbirliği yaparak, ortak ihtiyaçlarını karşılayabilmek amacıyla oluşturulmaktadırlar. Türkiye'de çeşit ve sayı olarak fazlaca bulunan kooperatiflerin öz kaynak, kredi ve sermaye yetersizliği gibi birtakım sorunları vardır. Kooperatifler bu sorunlar yüzünden ne yazık ki istenilen ölçüde gelişememişlerdir. Kooperatifçilik hareketinin sorunlarının çözülmesi, kendisinden beklenen ekonomik ve sosyal görevleri yerine getirebilmesi için Türkiye'de kooperatiflerin finansal sorunlarının çözümü gerekmektedir. Kooperatif Bankaları, kooperatiflerin finansman sorununu çözmede etkin araç olarak görülmektedir. Kooperatif Bankaları, kooperatif ve üst örgütleri tarafından kurulup işletilen, onlar tarafından sahip olunan ve onlara kredi veren bir kuruluştur. Kooperatif bankacılığı sistemi ise kısaca kooperatiflere kredi veren ve kooperatifler üst örgütleri tarafından yönetilen bankalardır. Avrupa Birliği'nde Kooperatif Bankacılığı ve Türkiye'de uygulanabilirliği isimli tez çalışmamızın birinci bölümünde; kooperatifler ve kooperatif bankacılığı hakkında genel bilgiler verilmiştir. İkinci bölümde; Avrupa Birliği'ne üye ülkelerde Kooperatif Bankacılığı'nın tarihsel gelişimi ve Kooperatifler Bankası uygulamaları incelenmiştir. Üçüncü ve son bölümde ise; Türkiye'de kurulması istenen Kooperatifler Bankası'nın mevcut şartlarda kurulup kurulamayacağı ve kurulması için gerekli olan şartlar ve Türkiye için model önerileri incelenmiştir
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