Radiative energy budget estimates for the 1979 Southwest Summer Monsoon

November, 1986.Includes bibliographical references

GATE phase III mean synoptic-scale radiative convergence profiles

March, 1980.Includes bibliographical references.Sponsored by the Global Atmospheric Research Program, National Science Foundation and the GARP Atlantic Tropical Experiment (GATE) Project Office, NOAA ATM 78-05743.Sponsored by the Global Atmospheric Research Program, National Science Foundation and the GARP Atlantic Tropical Experiment (GATE) Project Office, NOAA ATM 78-12631

Comparison of NOAA-9 ERBE measurements with Cirrus IFO satellite and aircraft measurements

Earth Radiation Budget Experiment (ERBE) measurements onboard the NOAA-9 are compared for consistency with satellite and aircraft measurements made during the Cirrus Intensive Field Observation (IFO) of October 1986. ERBE scene identification is compared with NOAA-9 TIROS Operational Vertical Sounder (TOVS) cloud retrievals; results from the ERBE spectral inversion algorithms are compared with High resolution Interferometer Sounder (HIS) measurements; and ERBE radiant existance measurements are compared with aircraft radiative flux measurements

Sensitivity analyses for effect modifiers not observed in the target population when generalizing treatment effects from a randomized controlled trial: Assumptions, models, effect scales, data scenarios, and implementation details

Background: Randomized controlled trials are often used to inform policy and practice for broad populations. The average treatment effect (ATE) for a target population, however, may be different from the ATE observed in a trial if there are effect modifiers whose distribution in the target population is different that from that in the trial. Methods exist to use trial data to estimate the target population ATE, provided the distributions of treatment effect modifiers are observed in both the trial and target population -- an assumption that may not hold in practice. Methods: The proposed sensitivity analyses address the situation where a treatment effect modifier is observed in the trial but not the target population. These methods are based on an outcome model or the combination of such a model and weighting adjustment for observed differences between the trial sample and target population. They accommodate several types of outcome models: linear models (including single time outcome and pre- and post-treatment outcomes) for additive effects, and models with log or logit link for multiplicative effects. We clarify the methods' assumptions and provide detailed implementation instructions. Illustration: We illustrate the methods using an example generalizing the effects of an HIV treatment regimen from a randomized trial to a relevant target population. Conclusion: These methods allow researchers and decision-makers to have more appropriate confidence when drawing conclusions about target population effects

Investigation of the radiative boundary conditions during the development of the southwest monsoon Saudi Arabian heat low, An

January 1982.Includes bibliographical references.Progress report no. 2 on the cooperative research project between the Department of Atmospheric Science at Colorado State University and the Faculty of Meteorology and Environmental Science at King Abdul-Aziz University in accordance with the CID-ARME TED Project of the University of Arizona. Period covered August 16-November 30, 1981.CID contract #CSU-SA-KAU-02

An Integrated Approach for Characterizing Aerosol Climate Impacts and Environmental Interactions

Aerosols exert myriad influences on the earth's environment and climate, and on human health. The complexity of aerosol-related processes requires that information gathered to improve our understanding of climate change must originate from multiple sources, and that effective strategies for data integration need to be established. While a vast array of observed and modeled data are becoming available, the aerosol research community currently lacks the necessary tools and infrastructure to reap maximum scientific benefit from these data. Spatial and temporal sampling differences among a diverse set of sensors, nonuniform data qualities, aerosol mesoscale variabilities, and difficulties in separating cloud effects are some of the challenges that need to be addressed. Maximizing the long-term benefit from these data also requires maintaining consistently well-understood accuracies as measurement approaches evolve and improve. Achieving a comprehensive understanding of how aerosol physical, chemical, and radiative processes impact the earth system can be achieved only through a multidisciplinary, inter-agency, and international initiative capable of dealing with these issues. A systematic approach, capitalizing on modern measurement and modeling techniques, geospatial statistics methodologies, and high-performance information technologies, can provide the necessary machinery to support this objective. We outline a framework for integrating and interpreting observations and models, and establishing an accurate, consistent, and cohesive long-term record, following a strategy whereby information and tools of progressively greater sophistication are incorporated as problems of increasing complexity are tackled. This concept is named the Progressive Aerosol Retrieval and Assimilation Global Observing Network (PARAGON). To encompass the breadth of the effort required, we present a set of recommendations dealing with data interoperability; measurement and model integration; multisensor synergy; data summarization and mining; model evaluation; calibration and validation; augmentation of surface and in situ measurements; advances in passive and active remote sensing; and design of satellite missions. Without an initiative of this nature, the scientific and policy communities will continue to struggle with understanding the quantitative impact of complex aerosol processes on regional and global climate change and air quality

Intracranial chordoma presenting as acute hemorrhage in a child: Case report and literature review

BACKGROUND: Chordomas are rare, slow-growing malignant neoplasms derived from remnants of the embryological notochord. Pediatric cases comprise only 5% of all chordomas, but more than half of the reported pediatric chordomas are intracranial. For patients of all ages, intracranial chordomas typically present with symptoms such as headaches and progressive neurological deficits occurring over several weeks to many years as they compress or invade local structures. There are only reports of these tumors presenting acutely with intracranial hemorrhage in adult patients. CASE DESCRIPTION: A 10-year-old boy presented with acute onset of headache, emesis, and diplopia. Head computed tomography and magnetic resonance imaging of brain were suspicious for a hemorrhagic mass located in the left petroclival region, compressing the ventral pons. The mass was surgically resected and demonstrated acute intratumoral hemorrhage. Pathologic examination was consistent with chordoma. CONCLUSION: There are few previous reports of petroclival chordomas causing acute intracranial hemorrhage. To the authors' knowledge, this is the first case of a petroclival chordoma presenting as acute intracranial hemorrhage in a pediatric patient. Although uncommon, it is important to consider chordoma when evaluating a patient of any age presenting with a hemorrhagic lesion of the clivus

Anti-inflammatory and safety profile of DuP 697, a novel orally effective prostaglandin synthesis inhibitor

ABBREVIATiONS: NSAID, nonsteroidal anti-inflammatory drugs; PG. prostaglandin; RBF, renal blood flow; All, angiotensin II; POW, phenylquinon

The state of the Martian climate

60°N was +2.0°C, relative to the 1981–2010 average value (Fig. 5.1). This marks a new high for the record. The average annual surface air temperature (SAT) anomaly for 2016 for land stations north of starting in 1900, and is a significant increase over the previous highest value of +1.2°C, which was observed in 2007, 2011, and 2015. Average global annual temperatures also showed record values in 2015 and 2016. Currently, the Arctic is warming at more than twice the rate of lower latitudes