Sonographically Guided Patellar Tendon Fenestration

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/135446/1/jum2013325771.pd

UV-Spectrophotometric Determination of Telmisartan and Hydrochlorothiazide in Combined Tablet Dosage Form Using Simultaneous Equation Method

A UV spectrophotometric method was developed for the estimation of Telmisartan and Hydrochlorothiazide in Combined Tablet Dosage Form Using Simultaneous Equation Method. The drug obeyed the Beers law and shows good correlation near to r 2 = 0.999 for Telmisartan and for Hydrochlorothiazide r 2 =0.999.Absorption maxima of Telmisartan 296.8 nm and Hydrochlorothiazide 271.2 nm. Beers law was obeyed in concentration rang of 5-30 g/ml for Telmisartan and 2-12 g/ml for Hydrochlorothiazide. The method has been validated for linearity, accuracy and precision. The recovery was 99.28 % for Telmisartan and 99.26% for Hydrochlorothiazide. The developed method was found to be accurate, simple, precise, economical, and selective for simultaneous estimation of Telmisartan and Hydrochlorothiazide in tablet formulations

Posterior Interosseous Nerve of the Elbow

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/135289/1/jum2010295691.pd

Usefulness of the Twinkling Artifact in Identifying Implanted Mesh After Inguinal Hernia Repair

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/135644/1/jum20113081059.pd

“We are the soul, pearl and beauty of Hindu Kush Mountains”: exploring resilience and psychological wellbeing of Kalasha, an ethnic and religious minority group in Pakistan

The Kalasha are a marginalized ethnic and religious minority group in northern Pakistan. The Kalasha minority is known for their divergent polytheistic beliefs, and represents the outliers of the collectively monotheistic Muslim population of Pakistan. This study aimed to explore the psychological resilience beliefs and lived experiences of the Kalasha and to identify cultural protective factors and indigenous beliefs that help them maintain psychological wellbeing and resilience. Seven semi-structured interviews and two focus-group discussions were conducted. The total sample consisted of 6 women and 8 men, aged 20–58 years (Mage = 36.29, SD = 12.58). The Interpretative Phenomenological Analysis qualitative method was chosen. Study findings identified that factors contributing to the wellbeing, happiness and resilience enhancement beliefs of Kalasha included five main themes, all influenced by their unique spirituality: contentment, pride in social identity, tolerance, gender collaboration and gratitude. The study also revealed the Kalasha’s perception of their marginalization related to challenges and threats. The Kalasha emphasized bringing these resilience enhancement beliefs into practice, as a mean to buffer against challenges. In conclusion, this study revealed Kalasha’s wellbeing and resilience enhancement factors, which they believed in and practiced as an element of their indigenous culture and religion

Intraperitoneal drain placement and outcomes after elective colorectal surgery: international matched, prospective, cohort study

Despite current guidelines, intraperitoneal drain placement after elective colorectal surgery remains widespread. Drains were not associated with earlier detection of intraperitoneal collections, but were associated with prolonged hospital stay and increased risk of surgical-site infections.Background Many surgeons routinely place intraperitoneal drains after elective colorectal surgery. However, enhanced recovery after surgery guidelines recommend against their routine use owing to a lack of clear clinical benefit. This study aimed to describe international variation in intraperitoneal drain placement and the safety of this practice. Methods COMPASS (COMPlicAted intra-abdominal collectionS after colorectal Surgery) was a prospective, international, cohort study which enrolled consecutive adults undergoing elective colorectal surgery (February to March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included: rate and time to diagnosis of postoperative intraperitoneal collections; rate of surgical site infections (SSIs); time to discharge; and 30-day major postoperative complications (Clavien-Dindo grade at least III). After propensity score matching, multivariable logistic regression and Cox proportional hazards regression were used to estimate the independent association of the secondary outcomes with drain placement. Results Overall, 1805 patients from 22 countries were included (798 women, 44.2 per cent; median age 67.0 years). The drain insertion rate was 51.9 per cent (937 patients). After matching, drains were not associated with reduced rates (odds ratio (OR) 1.33, 95 per cent c.i. 0.79 to 2.23; P = 0.287) or earlier detection (hazard ratio (HR) 0.87, 0.33 to 2.31; P = 0.780) of collections. Although not associated with worse major postoperative complications (OR 1.09, 0.68 to 1.75; P = 0.709), drains were associated with delayed hospital discharge (HR 0.58, 0.52 to 0.66; P < 0.001) and an increased risk of SSIs (OR 2.47, 1.50 to 4.05; P < 0.001). Conclusion Intraperitoneal drain placement after elective colorectal surgery is not associated with earlier detection of postoperative collections, but prolongs hospital stay and increases SSI risk

Interactive effects of the APOE and BDNF polymorphisms on functional brain connectivity: the Tasmanian Healthy Brain Project

Resting-state functional magnetic resonance imaging measures pathological alterations in neurodegenerative diseases, including Alzheimer's disease. Disruption in functional connectivity may be a potential biomarker of ageing and early brain changes associated with AD-related genes, such as APOE and BDNF. The objective of this study was to identify group differences in resting-state networks between individuals with BDNF Val66Met and APOE polymorphisms in cognitively healthy older persons. Dual regression following Independent Components Analysis were performed to examine differences associated with these polymorphisms. APOE ε3 homozygotes showed stronger functional connectivity than APOE ε4 carriers. Males showed stronger functional connectivity between the Default Mode Network (DMN) and grey matter premotor cortex, while females showed stronger functional connectivity between the executive network and lateral occipital cortex and parahippocampal gyrus. Additionally, we found that with increasing cognitive reserve, functional connectivity increased within the Dorsal Attention Network (DAN), but decreased within the DMN. Interaction effects indicated stronger functional connectivity in Met/ε3 carriers than in Met/ε4 and Val/ε4 within both the DMN and DAN. APOE/BDNF interactions may therefore influence the integrity of functional brain connections in older adults, and may underlie a vulnerable phenotype for subsequent Alzheimer's-type dementia

Review On Die Spot Welding Machine

Resistance spot welding is widely used in the fabrication of vehicle bodies andparts of their equipment. The article presents the methodology and the results of non-destructive ultrasonic testing of resistance spot welded joints of thin steel sheet with closed profile. Non-destructive test results were verified on the basis of welded joint area after destructive testing. The obtained results were used to develop an assessment technique for spot welded joints of closed profile with steel sheet, which could be used in factories employing such joints. In addition, the article makes comparison between the costs of the developed assessment technique and currently used destructivemethod.This paper addresses the mechanical properties of ferrite steel resistance spot welds during quasi-static tensile test. The mechanical properties are described in terms of peak load. It was shown that the fusion zone size is the most important. The fusion zone size can control the solidification of the grain which controlling factor of spot weld peak load. The dendritic grain and equiaxial axial grains occurred in the microstructures of the welded specimens joined at various welding currents and electrode forces. The failure mechanism of resistance spot welds during tensile test was studied with the aid of thermography. The thermography gives visible data of temperature changes on the surface of specimen. In light of the failure mechanism, the simple model is proposed to ensure pull out failuremode

Perception regarding impact of social media and cinema on materialism, and social comparison among youth perusing medical & paramedical courses: A cross sectional study

Background: Globalization has increased the significance of materialistic possessions in one’s life. It is the pride one finds in possessing and owning material goods. Social comparison is a form of sociological self-esteem, where we derive our sense of self through comparing ourselves with others. In India majority of the population youth. Both social media and Cinema have tremendous impact on youth influencing their materialistic and social comparison behaviour. Objectives-The proposed study aims to explore the perception of youth impact of social media and cinema on materialism and social comparison & also to explore use and misuse of social media among youth who are pursuing medical & para medical courses. Methodology: A cross-sectional study was conducted among various medical and paramedical colleges in study area. A pre-tested questionnaire was used on causes for materialism and social comparison was via online using Google forms. Descriptive statistics were computed on the socio-demographic parameters. Chi-square test statistics was used to find the association between the variables. A reliability analysis, using Cronbach’s alpha (œ = 0.74), was undertaken to test the reliability of each of the materialism factors