Improvement of Pineapple Production on Tropical Peat Through Fertilizer Use

Information on the agronomic characteristics and nutritional requirements of pineapple (cv. Gandul) is lacking in peat soil. Therefore, studies in the field at two sites (site 1 and site 2), glasshouse and laboratory were carried out to investigate the effects of N, P, K, Ca, Mg and Cu on growth, yield and quality of pineapple and to assess the loss of the applied nutrients through leaching. Six levels of each of N, P, K, Ca, Mg and Cu were studied separately at each site of the field in a RCB design with three replications. In the glasshouse, three levels of each of the above nutrients were studied with soils from both sites. Leaching studies using soil columns were conducted in the laboratory with two levels of each nutrient for a period of 3 0 days. Plant height and leaf number increased with age up to forcing time at both sites. D-leaf length and area were influenced with N application, while the leaf dry weight was influenced with Mg at site 2 . The leaf nutrient concentrations were influenced by N, P, Ca and Mg at site 1 and by N, P and K applications at site 2. Leaf nutrient concentrations increased up to six months of plant age and declined at forcing at both sites. The mean fruit weight of pineapple responded quadratically with N application at both sites and with Ca at site 1 and declined linearly with the increment of P at site 2. There was no significant effect of nutrients on fruit quality except for P on sugar content at site 1 . Fruit yield was positively correlated with leaf N concentrations at both sites and negatively correlated with Cu at site 1

Debranching improves morpho - physiological characters, fruit quality and yield of tomato

Farmers are commercially cultivated tomato with different levels of shoot pruning but this production practice has not been defined clearly. The experiment was conducted under sub-tropical condition to assess the effect of different levels of debranching on morpho-physiological, reproductive and yield contributing characters in determinate tomato cultivar cv. Binatomato-5. The debranching levels were: i) control, ii) only mainstem (MS), iii) MS with 2 branches, iv) MS with 3 branches and v) MS with 4 branches. Based on recommended spacing (50 cm × 50 cm), the higher fruit yield plant⁻¹ as well as ruit yield per hectare were observed in more branch bearing plants of the treatment control (MS with 5-6 branches), MS with 3 branches and MS with 4 branches due to production of higher number of fruits plant⁻¹ with being the highest in MS with 3 branches due to increase fruit size. The lowest fruit yield per plant as well as per hectare was observed in uniculm plants due to lower number of fruits per plant. This study suggests that plants that have MS with three branches may be recommended for commercial cultivation of tomato under sub-tropical condition

Gamma-Ray Bursts: Progress, Problems & Prospects

The cosmological gamma-ray burst (GRB) phenomenon is reviewed. The broad observational facts and empirical phenomenological relations of the GRB prompt emission and afterglow are outlined. A well-tested, successful fireball shock model is introduced in a pedagogical manner. Several important uncertainties in the current understanding of the phenomenon are reviewed, and prospects of how future experiments and extensive observational and theoretical efforts may address these problems are discussed.Comment: 86 pages, 17 figures, 566 references, an invited review for International Journal of Modern Physics A, in pres

Neutrino Mixing and Neutrino Telescopes

Measuring flux ratios of ultra-high energy neutrinos is an alternative method to determine the neutrino mixing angles and the CP phase delta. We conduct a systematic analysis of the neutrino mixing probabilities and of various flux ratios measurable at neutrino telescopes. The considered cases are neutrinos from pion, neutron and muon-damped sources. Explicit formulae in case of mu-tau symmetry and its special case tri-bimaximal mixing are obtained, and the leading corrections due to non-zero theta_{13} and non-maximal theta_{23} are given. The first order correction is universal as it appears in basically all ratios. We study in detail its dependence on theta_{13}, theta_{23} and the CP phase, finding that the dependence on theta_{23} is strongest. The flavor compositions for the considered neutrino sources are evaluated in terms of this correction. A measurement of a flux ratio is a clean measurement of the universal correction (and therefore of theta_{13}, theta_{23} and delta) if the zeroth order ratio does not depend on theta_{12}. This favors pion sources over the other cases, which in turn are good candidates to probe theta_{12}. The only situations in which the universal correction does not appear are certain ratios in case of a neutron and muon-damped source, which depend mainly on theta_{12} and receive only quadratic corrections from the other parameters. We further show that there are only two independent neutrino oscillation probabilities, give the allowed ranges of the considered flux ratios and of all probabilities, and show that none of the latter can be zero or one.Comment: 29 pages, 8 figures. Minor changes, to appear in JCA

Neutrino signatures of the supernova - gamma ray burst relationship

We calculate the TeV-PeV neutrino fluxes of gamma-ray bursts associated with supernovae, based on the observed association between GRB 030329 and supernova SN 2003dh. The neutrino spectral flux distributions can test for possible delays between the supernova and the gamma-ray burst events down to much shorter timescales than what can be resolved with photons. As an illustrative example, we calculate the probability of neutrino induced muon and electron cascade events in a km scale under-ice detector at the South Pole, from the GRB 030329. Our calculations demonstrate that km scale neutrino telescopes are expected to detect signals that will allow to constrain supernova-GRB models.Comment: 7 pages, 2 figures. Accepted for publication in Phys. Rev.

Blockade of advanced glycation end product formation attenuates bleomycin-induced pulmonary fibrosis in rats

<p>Abstract</p> <p>Background</p> <p>Advanced glycation end products (AGEs) have been proposed to be involved in pulmonary fibrosis, but its role in this process has not been fully understood. To investigate the role of AGE formation in pulmonary fibrosis, we used a bleomycin (BLM)-stimulated rat model treated with aminoguanidine (AG), a crosslink inhibitor of AGE formation.</p> <p>Methods</p> <p>Rats were intratracheally instilled with BLM (5 mg/kg) and orally administered with AG (40, 80, 120 mg/kg) once daily for two weeks. AGEs level in lung tissue was determined by ELISA and pulmonary fibrosis was evaluated by Ashcroft score and hydroxyproline assay. The expression of heat shock protein 47 (HSP47), a collagen specific molecular chaperone, was measured with RT-PCR and Western blot. Moreover, TGFβ1 and its downstream Smad proteins were analyzed by Western blot.</p> <p>Results</p> <p>AGEs level in rat lungs, as well as lung hydroxyproline content and Ashcroft score, was significantly enhanced by BLM stimulation, which was abrogated by AG treatment. BLM significantly increased the expression of HSP47 mRNA and protein in lung tissues, and AG treatment markedly decreased BLM-induced HSP47 expression in a dose-dependent manner (p < 0.05). In addition, AG dose-dependently downregulated BLM-stimulated overexpressions of TGFβ1, phosphorylated (p)-Smad2 and p-Smad3 protein in lung tissues.</p> <p>Conclusion</p> <p>These findings suggest AGE formation may participate in the process of BLM-induced pulmonary fibrosis, and blockade of AGE formation by AG treatment attenuates BLM-induced pulmonary fibrosis in rats, which is implicated in inhibition of HSP47 expression and TGFβ/Smads signaling.</p

Deletion of PTH Rescues Skeletal Abnormalities and High Osteopontin Levels in Klotho−/− Mice

Maintenance of normal mineral ion homeostasis is crucial for many biological activities, including proper mineralization of the skeleton. Parathyroid hormone (PTH), Klotho, and FGF23 have been shown to act as key regulators of serum calcium and phosphate homeostasis through a complex feedback mechanism. The phenotypes of Fgf23−/− and Klotho−/− (Kl−/−) mice are very similar and include hypercalcemia, hyperphosphatemia, hypervitaminosis D, suppressed PTH levels, and severe osteomalacia/osteoidosis. We recently reported that complete ablation of PTH from Fgf23−/− mice ameliorated the phenotype in Fgf23−/−/PTH−/− mice by suppressing serum vitamin D and calcium levels. The severe osteomalacia in Fgf23−/− mice, however, persisted, suggesting that a different mechanism is responsible for this mineralization defect. In the current study, we demonstrate that deletion of PTH from Kl−/− (Kl−/−/PTH−/− or DKO) mice corrects the abnormal skeletal phenotype. Bone turnover markers are restored to wild-type levels; and, more importantly, the skeletal mineralization defect is completely rescued in Kl−/−/PTH−/− mice. Interestingly, the correction of the osteomalacia is accompanied by a reduction in the high levels of osteopontin (Opn) in bone and serum. Such a reduction in Opn levels could not be observed in Fgf23−/−/PTH−/− mice, and these mice showed sustained osteomalacia. This significant in vivo finding is corroborated by in vitro studies using calvarial osteoblast cultures that show normalized Opn expression and rescued mineralization in Kl−/−/PTH−/− mice. Moreover, continuous PTH infusion of Kl−/− mice significantly increased Opn levels and osteoid volume, and decreased trabecular bone volume. In summary, our results demonstrate for the first time that PTH directly impacts the mineralization disorders and skeletal deformities of Kl−/−, but not of Fgf23−/− mice, possibly by regulating Opn expression. These are significant new perceptions into the role of PTH in skeletal and disease processes and suggest FGF23-independent interactions of PTH with Klotho

Mass hierarchy, 2-3 mixing and CP-phase with Huge Atmospheric Neutrino Detectors

We explore the physics potential of multi-megaton scale ice or water Cherenkov detectors with low ($\sim 1$ GeV) threshold. Using some proposed characteristics of the PINGU detector setup we compute the distributions of events versus neutrino energy $E_\nu$ and zenith angle $\theta_z$, and study their dependence on yet unknown neutrino parameters. The $(E_\nu - \theta_z)$ regions are identified where the distributions have the highest sensitivity to the neutrino mass hierarchy, to the deviation of the 2-3 mixing from the maximal one and to the CP-phase. We evaluate significance of the measurements of the neutrino parameters and explore dependence of this significance on the accuracy of reconstruction of the neutrino energy and direction. The effect of degeneracy of the parameters on the sensitivities is also discussed. We estimate the characteristics of future detectors (energy and angle resolution, volume, etc.) required for establishing the neutrino mass hierarchy with high confidence level. We find that the hierarchy can be identified at $3\sigma$ -- $10\sigma$ level (depending on the reconstruction accuracies) after 5 years of PINGU operation.Comment: 39 pages, 21 figures. Description of Fig.3 correcte

Fermi observations of high-energy gamma-ray emission from GRB 090217A

The Fermi observatory is advancing our knowledge of Gamma-Ray Bursts (GRBs) through pioneering observations at high energies, covering more than 7 decades in energy with the two on-board detectors, the Large Area Telescope (LAT) and the Gamma-ray Burst Monitor (GBM). Here we report on the observation of the long GRB 090217A which triggered the GBM and has been detected by the LAT with a significance greater than 9 sigma. We present the GBM and LAT observations and on-ground analyses, including the time-resolved spectra and the study of the temporal profile from 8 keV up to 1 GeV. All spectra are well reproduced by a Band model. We compare these observations to the first two LAT-detected, long bursts GRB 080825C and GRB 080916C. These bursts were found to have time-dependent spectra and exhibited a delayed onset of the high-energy emission, which are not observed in the case of GRB 090217A. We discuss some theoretical implications for the high-energy emission of GRBs.Comment: 17 pages, 4 figures. Contact Authors: Fred, Piron; Sara, Cutini; Andreas, von Kienli

The ANTARES Telescope Neutrino Alert System

The ANTARES telescope has the capability to detect neutrinos produced in astrophysical transient sources. Potential sources include gamma-ray bursts, core collapse supernovae, and flaring active galactic nuclei. To enhance the sensitivity of ANTARES to such sources, a new detection method based on coincident observations of neutrinos and optical signals has been developed. A fast online muon track reconstruction is used to trigger a network of small automatic optical telescopes. Such alerts are generated for special events, such as two or more neutrinos, coincident in time and direction, or single neutrinos of very high energy.Comment: 17 pages, 9 figures submitted to Astroparticle Physic