1,142 research outputs found

    Mixing ratios of trace gases in the austral polar atmosphere during August and September of 1987

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    Mixing ratios are presented for a number of long-lived trace gases in the austral polar atmosphere during August and September of 1987. The recent discovery of a 12-year trend of increasing depletion of ozone over the Antarctic Continent in the spring of each year led to numerous theoretical interpretations and several scientific expeditions to the region. The results herein were obtained as part of a major effort involving penetration of the region of ozone depletion by NASA's multi-instrumented aircraft. One of the 14 instruments on the high-altitude ER-2 aircraft collected pressurized air samples between latitudes of 53 degrees and 72 degrees south at pressure altitudes up to 21 km in a series of 12 flights from Punta Arenas, Chile, over the Palmer Peninsula. The sampling system, located in the nose section of ER-2, has an inlet tube in the free airstream, a metal-bellows air pump, and 14 specially treated 1.6 l stainless-steel canisters for containing the pressurized air at 350 kPa. A typical flight profile consisted of a southbound path on the 428 K potential temperature surface, a descent to a pressure altitude of 13.7 km, a climb to the 460 K surface, and return on this surface. Mixing ratios for the trace gases were obtained from gas chromatographic analyses of the pressurized air samples. Of the species measured, the mixing ratios for CH4, CO, N2O, CF2 Cl2, CFCl3, CH3, CCl3, CCl4, and C2F3Cl3 are reported here

    The micrometeoroid complex and evolution of the lunar regolith

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    The interaction of the micrometeoroid complex with the lunar surface is evidenced by numerous glass-lined microcraters on virtually every lunar surface exposed to space. Such craters range in size from less than .1 micron to approximately 2 sq cm diameter. Using small scale laboratory cratering experiments for calibration, the observed crater-sized frequency distributions may be converted into micrometeoroid mass distributions. These lunar mass distributions are in essential agreement with satellite data. Some physical properties of micrometeoroids may be deduced by comparing lunar crater geometries with those obtained in laboratory experiments. The proponderance of circular outlines of lunar microcraters necessitates equidimensional, if not spherical, micrometeoroids

    The Academics Athletics Trade-off: Universities and Intercollegiate Athletics

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    This analysis focuses on several key issues in the Football Bowl Subdivision (FBS). The intrinsic benefits of athletic programs are discussed in the first section. Trends in graduation rates and academic performance among athletes and how they correlate with the general student body are discussed in the second section. Finally, an overview of the revenues and expenses of athletic department budgets are discussed in an effort to gain a better understanding of the allocation of funds to athletics. In spite of recent growth in revenues and expenses, the athletic department budget comprises on average only 5 percent of the entire university budget at an FBS school, though spending and revenues have increased dramatically in recent years. In the grand scheme of things, American higher education faces several other, arguably more pressing, areas of reform. However, athletics is a significant and growing dimension of higher education that warrants in-depth examination

    Simulations of Mixed Morphology Supernova Remnants With Anisotropic Thermal Conduction

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    We explore the role of anisotropic thermal conduction on the evolution of supernova remnants through interstellar media with a range of densities via numerical simulations. We find that a remnant expanding in a dense environment can produce centre-bright hard x-ray emission within 20 kyr, and centre-bright soft x-ray emission within 60 kyr of the supernova event. In a more tenuous environment, the appearance of a centre-bright structure in hard x-rays is delayed until about 60 kyr. The soft x-ray emission from such a remnant may not become centre bright during its observable lifetime. This can explain the observations that show that mixed-morphology supernova remnants preferentially occur close to denser, molecular environments. Remnants expanding into denser environments tend to be smaller, making it easier for thermal conduction to make larger changes in the temperatures of their hot gas bubbles. We show that the lower temperatures make it very favorable to use high-stage ions as diagnostics of the hot gas bubbles in SNRs. In particular, the distribution of O VIII transitions from shell-bright at early epochs to centre-bright at later epochs in the evolution of an SNR expanding in a dense ISM when the physics of thermal conduction is included.Comment: 8 pages, 5 figures, submitted to Monthly Notice

    Theoretical study of the absorption spectra of the sodium dimer

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    Absorption of radiation from the sodium dimer molecular states correlating to Na(3s)-Na(3s) is investigated theoretically. Vibrational bound and continuum transitions from the singlet X Sigma-g+ state to the first excited singlet A Sigma-u+ and singlet B Pi-u states and from the triplet a Sigma-u+ state to the first excited triplet b Sigma-g+ and triplet c Pi-g states are studied quantum-mechanically. Theoretical and experimental data are used to characterize the molecular properties taking advantage of knowledge recently obtained from ab initio calculations, spectroscopy, and ultra-cold atom collision studies. The quantum-mechanical calculations are carried out for temperatures in the range from 500 to 3000 K and are compared with previous calculations and measurements where available.Comment: 19 pages, 8 figures, revtex, eps

    Gender Differences in the Romantic Commitment of Swingers: A Quantitative and Qualitative Analysis

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    This research examined whether gender differences in romantic commitment among a swing population are mediated by sexual permissiveness. This study also served as an update to past literature and further exploration into swing culture by using qualitative data„such as examining reasons for entering and leaving swinging, level of involvement in the lifestyle, and safe sex practices. Researchers have found significant correlations between gender and commitment (Cupach & Meets, 1995; Duffy & Rusbult,1985-1986), gender and sexual permissiveness (Hong,1991; LaBeff & Dodder, 1982; Oliver & Hyde, 1993), and sexual permissiveness and commitment (Oliver & Sedikides, 1992; Yela, 2000). However, the role that sexual permissiveness may play as a mediator between gender and commitment has yet to be examined. One hundred fitly swingers recruited through swing club directors completed a battery of surveys online. Independent samples t-tests were used to analyze the results of the primary quantitative portion of this study. Sexual permissiveness did not mediate the relationship between gender and commitment. Qualitative content coding and chi-square tests of independence were used to assess important information about the current swing population such as level of involvement in the lifestyle and safe sex behaviors. Both relationship status and sexual orientation were significantly related to gender. Content coding of open-ended qualitative questions revealed reasons that swingers initially begin swinging mainly to add value to their sex life and to contribute to their relationship. Content coding regarding the positive and negative influences to the relationship due to participating in swinging revealed that participants found more positive influences to the relationship such as swinging adds to the relationship. Chi-square tests of independence revealed no gender differences in voluntary STI testing or rate of STI infection. In addition, content coding demonstrated that both genders have a high rate of utilizing precautionary measures such as condoms to prevent transmission of STIs/HIV

    Effects of sea level rise on economy of the United States

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    We report the first ex post study of the economic impact of sea level rise. We apply two econometric approaches to estimate the past effects of sea level rise on the economy of the USA, viz. Barro type growth regressions adjusted for spatial patterns and a matching estimator. Unit of analysis is 3063 counties of the USA. We fit growth regressions for 13 time periods and we estimated numerous varieties and robustness tests for both growth regressions and matching estimator. Although there is some evidence that sea level rise has a positive effect on economic growth, in most specifications the estimated effects are insignificant. We therefore conclude that there is no stable, significant effect of sea level rise on economic growth. This finding contradicts previous ex ante studies

    Evaluation of a short RNA within Prostate Cancer Gene 3 in the predictive role for future cancer using non-malignant prostate biopsies.

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    BACKGROUND: Prostate Cancer 3 (PCA3) is a long non-coding RNA (ncRNA) upregulated in prostate cancer (PCa). We recently identified a short ncRNA expressed from intron 1 of PCA3. Here we test the ability of this ncRNA to predict the presence of cancer in men with a biopsy without PCa. METHODS: We selected men whose initial biopsy did not identify PCa and selected matched cohorts whose subsequent biopsies revealed PCa or benign tissue. We extracted RNA from the initial biopsy and measured PCA3-shRNA2, PCA3 and PSA (qRT-PCR). RESULTS: We identified 116 men with and 94 men without an eventual diagnosis of PCa in 2-5 biopsies (mean 26 months), collected from 2002-2008. The cohorts were similar for age, PSA and surveillance period. We detected PSA and PCA3-shRNA2 RNA in all samples, and PCA3 RNA in 90% of biopsies. The expression of PCA3 and PCA3-shRNA2 were correlated (Pearson's r = 0.37, p<0.01). There was upregulation of PCA3 (2.1-fold, t-test p = 0.02) and PCA3-shRNA2 (1.5-fold) in men with PCa on subsequent biopsy, although this was not significant for the latter RNA (p = 0.2). PCA3 was associated with the future detection of PCa (C-index 0.61, p = 0.01). This was not the case for PCA3-shRNA2 (C-index 0.55, p = 0.2). CONCLUSIONS: PCA3 and PCA3-shRNA2 expression are detectable in historic biopsies and their expression is correlated suggesting co-expression. PCA3 expression was upregulated in men with PCa diagnosed at a future date, the same did not hold for PCA3-shRNA2. Futures studies should explore expression in urine and look at a time course between biopsy and PCa detection

    Dynamic Group Diffie-Hellman Key Exchange under Standard Assumptions

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    Authenticated Diffie-Hellman key exchange allows two principals communicating over a public network, and each holding public /private keys, to agree on a shared secret value. In this paper we study the natural extension of this cryptographic problem to a group of principals. We begin from existing formal security models and refine them to incorporate major missing details (e.g., strong-corruption and concurrent sessions). Within this model we define the execution of a protocol for authenticated dynamic group Diffie-Hellman and show that it is provably secure under the decisional Diffie-Hellman assumption. Our security result holds in the standard model and thus provides better security guarantees than previously published results in the random oracle model

    Glucosylsphingosine Is a Highly Sensitive and Specific Biomarker for Primary Diagnostic and Follow-Up Monitoring in Gaucher Disease in a Non-Jewish, Caucasian Cohort of Gaucher Disease Patients

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    Gaucher disease (GD) is the most common lysosomal storage disorder (LSD). Based on a deficient β-glucocerebrosidase it leads to an accumulation of glucosylceramide. Standard diagnostic procedures include measurement of enzyme activity, genetic testing as well as analysis of chitotriosidase and CCL18/PARC as biomarkers. Even though chitotriosidase is the most well-established biomarker in GD, it is not specific for GD. Furthermore, it may be false negative in a significant percentage of GD patients due to mutation. Additionally, chitotriosidase reflects the changes in the course of the disease belatedly. This further enhances the need for a reliable biomarker, especially for the monitoring of the disease and the impact of potential treatments.Here, we evaluated the sensitivity and specificity of the previously reported biomarker Glucosylsphingosine with regard to different control groups (healthy control vs. GD carriers vs. other LSDs).Only GD patients displayed elevated levels of Glucosylsphingosine higher than 12 ng/ml whereas the comparison controls groups revealed concentrations below the pathological cut-off, verifying the specificity of Glucosylsphingosine as a biomarker for GD. In addition, we evaluated the biomarker before and during enzyme replacement therapy (ERT) in 19 patients, demonstrating a decrease in Glucosylsphingosine over time with the most pronounced reduction within the first 6 months of ERT. Furthermore, our data reveals a correlation between the medical consequence of specific mutations and Glucosylsphingosine.In summary, Glucosylsphingosine is a very promising, reliable and specific biomarker for GD
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