Artesanía: arte y vida

El TFG se basará en la en la fundamentación teória y puesta en práctica del oficio de artesano desde un análisis del contexto artístico, analizando todos los procesos, desde la obtención de las materias hasta su elaboración como obra artística acabada e incluyendo su exposición al público desde un punto de vista autónomo y autogestionado.Olmo Bresó, ÁD. (2017). Artesanía: arte y vida. http://hdl.handle.net/10251/92793TFG

A Hybrid FCC/HZSM-5 Catalyst for the Catalytic Cracking of a VGO/Bio-Oil Blend in FCC Conditions

The performance of a commercial FCC catalyst (designated as CY) and a physically mixed hybrid catalyst (80 wt.% CY and 20 wt.% HZSM-5-based catalyst, designated as CH) have been compared in the catalytic cracking of a vacuum gasoil (VGO)/bio-oil blend (80/20 wt.%) in a simulated riser reactor (C/O, 6gcatgfeed−1; t, 6 s). The effect of cracking temperature has been studied on product distribution (carbon products, water, and coke) and product lumps: CO+CO2, dry gas, liquified petroleum gases (LPG), gasoline, light cycle oil (LCO), heavy cycle oil (HCO), and coke. Using the CH catalyst, the conversion of the bio-oil oxygenates is ca. 3 wt.% higher, while the conversion of the hydrocarbons in the mixture is lower, yielding more carbon products (83.2–84.7 wt.% on a wet basis) and less coke (3.7–4.8 wt.% on a wet basis) than the CY catalyst. The CH catalyst provides lower gasoline yields (30.7–32.0 wt.% on a dry basis) of a less aromatic and more olefinic nature. Due to gasoline overcracking, enhanced LPG yields were also obtained. The results are explained by the high activity of the HZSM-5 zeolite for the cracking of bio-oil oxygenates, the diffusional limitations within its pore structure of bulkier VGO compounds, and its lower activity towards hydrogen transfer reactions.This work has been conducted with the financial support from the Ministry of Economy and Competitiveness of the Spanish Government (MINECO) (Project RTI2018-096981-B-I00), co-funded with FEDER funds, the Basque Government (Project IT1218-19), and the European Commission (Horizon 2020-MSCA RISE-2018, Contract No. 823745). Idoia Hita is thankful for her postdoctoral grant awarded by the Department of Education, University and Research of the Basque Government (Grant No. POS_2015_1_0035). Álvaro Ibarra is grateful for his PhD grant from the University of the Basque Country (UPV/EHU). Authors would also like to acknowledge Ikerlan/IK-4 for providing the raw bio-oil, as well as Petronor S.A. for providing the VGO and the equilibrated FCC catalyst for this study

Caracterización morfométrica de la cuenca del río Pudio (El Aljarafe, Sevilla). Análisis comparado de los último cincuenta años (1956-2006)

Morphometric caracterization of Pudio River basin (El Aljarafe, Sevilla). Compared analysis during the last fifty years (1956-2006). We analyzed the main morphometric features of the basin and drainage network of Pudio river (El Aljarafe, Sevilla) for the years 1956 and 2006. We compare both situations and show the experienced trend in the basin in the last fifty years. A significant loss of torrencial capacity has been observed , with channel disappearance, more significant at the basin top, and in connection with the above, a decline in the ability of erosive channels

Exposure to particulate matter: direct and indirect role in the COVID-19 pandemic

Knowing the transmission factors and the natural environment that favor the spread of a viral infection is crucial to stop outbreaks and develop effective preventive strategies. This work aims to evaluate the role of Particulate Matter (PM) in the COVID-19 pandemic, focusing especially on that of PM as a vector for SARS-CoV-2. Exposure to PM has been related to new cases and to the clinical severity of people infected by SARS-CoV-2, which can be explained by the oxidative stress and the inflammatory response generated by these particles when entering the respiratory system, as well as by the role of PM in the expression of ACE-2 in respiratory cells in human hosts. In addition, different authors have detected SARS-CoV-2 RNA in PM sampled both in outdoor and indoor environments. The results of various studies lead to the hypothesis that the aerosols emitted by an infected person could be deposited in other suspended particles, sometimes of natural but especially of anthropogenic origin, that form the basal PM. However, the viability of the virus in PM has not yet been demonstrated. Should PM be confirmed as a vector of transmission, prevention strategies ought to be adapted, and PM sampling in outdoor environments could become an indicator of viral load in a specific area.“This work has been carried out within the framework of the project “Air pollution and COVID-19: what can we learn from this pandemic?” of the Call for Grants from the BBVA Foundation to Scientific Research Teams in SARS-CoV-2 and COVID-19, in the area of Ecology and Veterinary Medicine

Mitochondrial activity and forward scatter vary in necrotic, apoptotic and membrane-intact spermatozoan subpopulations

P. 547-556In the present study, we have related mitochondrial membrane potential (ΔΨm) and forward scatter (FSC) to apoptotic-related changes in spermatozoa. Thawed red deer spermatozoa were incubated in synthetic oviductal fluid medium (37°C, 5% CO2), with or without antioxidant (100 μm Trolox). At 0, 3, 6 and 9 h, aliquots were assessed for motility and were stained with a combination of Hoechst 33342, propidium ioide (PI), YO-PRO-1 and Mitotracker Deep Red for flow cytometry. The proportion of spermatozoa YO-PRO-1+ and PI+ (indicating a damaged plasmalemma; DEAD) increased, whereas that of YO-PRO-1– and PI– (INTACT) spermatozoa decreased. The proportion of YO-PRO-1+ and PI– spermatozoa (altered plasmalemma; APOPTOTIC) did not change. Both DEAD and APOPTOTIC spermatozoa had low ΔΨm. Most high-ΔΨm spermatozoa were INTACT, and their proportion decreased with time. The FSC signal also differed between different groups of spermatozoa, in the order APOPTOTIC > DEAD > INTACT/low ΔΨm > INTACT/high ΔΨm; however, the actual meaning of this difference is not clear. APOPTOTIC spermatozoa seemed motile at 0 h, but lost motility with time. Trolox only slightly improved the percentage of INTACT spermatozoa (P < 0.05). The population of APOPTOTIC spermatozoa in the present study may be dying cells, possibly with activated cell death pathways (loss of ΔΨm). We propose that the sequence of spermatozoon death here would be: (1) loss of ΔΨm; (2) membrane changes (YO-PRO-1+ and PI–); and (3) membrane damage (PI+). INTACT spermatozoa with low ΔΨm or altered FSC may be compromised cells. The present study is the first that directly relates membrane integrity, apoptotic markers and mitochondrial status in spermatozoa. The results of the present study may help us understand the mechanisms leading to loss of spermatozoon viability after thawing.S

Implementation of the EIRA 3 Intervention by Targeting Primary Health Care Practitioners : Effectiveness in Increasing Physical Activity

The World Health Organization (WHO) estimated that physical inactivity (PI) is responsible for 20 to 30% of all non-communicable diseases. We aimed to analyze the effectiveness of a multiple health behavior change (MHBC) intervention to increase physical activity (PA) in patients 45 to 75 years old who had at least 2 of 3 unhealthy behaviors (tobacco use, reduced fruit and vegetable consumption, and insufficient PA). The MHBC intervention is based on the Transtheoretical Model and the conceptual framework of the "5 A's" and includes an individually tailored intervention, group sessions, and the use of community resources. We included 3062 participants, 1481 in the intervention group and 1581 in the control group. After 12 months, there were no differences in PA intensity measured by metabolic_equivalent_of_task_minutes/week (adjusted mean difference: 284.093, 95% CI: −298.24, 866.42) nor in the proportion of participants who increased PA levels to moderate or high (OR: 1.02, 95% CI: 0.85, 1.23; p = 0.822), and no differences in blood pressure, weight loss, or waist circumference. We found an increased proportion of patients in the intervention group who followed the WHO recommendations for PA (OR: 1.29; 95% CI: 1.04, 1.60; p = 0.02). We concluded that the intervention did not lead to a significant increase in PA

GHIA (Grupo de Herramientas Interactivas Avanzadas)

Es este documento se resumen las principales líneas actuales de investigación del grupo GHIA en lo que a informática educativa se refiere, así como su contexto y proyectos de futuro.This document summarizes the main research areas of GHIA regarding computer based learning, as well as its context and future work.En el momento actual, agradecemos su apoyo a los proyectos ASIES (TIN2010-17344) y Go-Lite (TIN2011-24139), financiados por el Ministerio de Educación, y al proyecto e-Madrid (S2009/TIC-1650), financiado por la Comunidad Autónoma de Madrid

EVI-LINHD, un Entorno Virtual de Investigación para la edición digital académica.

EVI-LINHD, un Entorno Virtual de Investigación para la edición digital académica

Cellular and humoral functional responses after BNT162b2 mRNA vaccination differ longitudinally between naive and subjects recovered from COVID-19

We have analyzed BNT162b2 vaccine-induced immune responses in naive subjects and individuals recovered from coronavirus disease 2019 (COVID-19), both soon after (14 days) and later after (almost 8 months) vaccination. Plasma spike (S)-specific immunoglobulins peak after one vaccine shot in individuals recovered from COVID-19, while a second dose is needed in naive subjects, although the latter group shows reduced levels all along the analyzed period. Despite how the neutralization capacity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mirrors this behavior early after vaccination, both groups show comparable neutralizing antibodies and S-specific B cell levels late post-vaccination. When studying cellular responses, naive individuals exhibit higher SARS-CoV-2-specific cytokine production, CD4+ T cell activation, and proliferation than do individuals recovered from COVID-19, with patent inverse correlations between humoral and cellular variables early post-vaccination. However, almost 8 months post-vaccination, SARS-CoV-2-specific responses are comparable between both groups. Our data indicate that a previous history of COVID-19 differentially determines the functional T and B cell-mediated responses to BNT162b2 vaccination over time.C.d.F., J.G.-P., and J.A. are supported by Instituto de Salud Carlos III (ISCII). We thank JM Ligos and Cytek Biosciences for their technical support. Research in E.L.-C.’s lab was supported by Fundación Familia Alonso, Santander Bank, Real Seguros, Fundación Mutua Madrileña, Fundación Uria, Fundación La Caixa, and Ayuntamiento de Madrid.S

Reflexión Política. Volumen 6 No. 11 de 2004

La Asociación Latinoamericana de Ciencia Política ha sido creada con el objetivo de coordinar, hacer más visible y potenciar las actividades de la disciplina de la región. Son miembros fundadores los participantes y asistentes al “1er Congreso Latinoamericano de Ciencia Política”, celebrado en la ciudad de Salamanca, España, los días 9, 10 y 11 de julio de 2002. Tiene como objetivos contribuir al perfeccionamiento de la disciplina en la región latinoamericana, facilitar el intercambio de información (principalmente a través de la publicación periódica de un boletín informativo) y otras formas de cooperación técnica entre sus miembros, apoyar los procesos de reforma y modernización de los sistemas políticos de la región y celebrar Congresos bianuales. La Secretaría de la Asociación tiene su sede en la Universidad de Salamanca. Esta Secretaría procurará establecer una red con los asociados para facilitar el intercambio y flujos de información entre los mismos.The Latin American Association of Political Science has been created with the objective of coordinating, making more visible and enhancing the activities of the discipline in the region. Founding members are the participants and attendees of the “1st Latin American Congress of Political Science”, held in the city of Salamanca, Spain, on July 9, 10 and 11, 2002. Its objectives are to contribute to the improvement of the discipline in the Latin American region, facilitate the exchange of information (mainly through the periodic publication of a newsletter) and other forms of technical cooperation among its members, support the reform and modernization processes of the political systems of the region and hold biannual Congresses. The Association's Secretariat has its headquarters at the University of Salamanca. This The Secretariat will seek to establish a network with partners to facilitate the exchange and flows of information between them